Suppressive effects of a pyrazole derivative of curcumin on airway inflammation and remodeling

Experimental and Molecular Pathology

Volumn 93, Issue 1, 2012, Pages 18-25

  Narumoto, Osamu ^a,b   Matsuo, Yukiko ^a   Sakaguchi, Masahiro ^c   Shoji, Shunsuke ^d   Yamashita, Naohide ^e   Schubert, David ^f   Abe, Kazuho ^a   Horiguchi, Kazuhide ^g   Nagase, Takahide ^b   Yamashita, Naomi ^a  

^a MUSASHINO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c AZABU UNIVERSITY   (Japan)

^d NATIONAL HOSPITAL ORGANIZATION   (Japan)

^e THE UNIVERSITY OF TOKYO   (Japan)

^f SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^g UNIVERSITY OF FUKUI   (Japan)

Author keywords

Airway remodeling; Asthma; Curcumin derivative; EMT

Indexed keywords

CNB 001; CURCUMIN; DEXAMETHASONE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 13; INTERLEUKIN 6; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; POLYINOSINIC POLYCYTIDYLIC ACID; PYRAZOLE DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN;

AIRWAY REMODELING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; BRONCHUS MUCOSA; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOASSAY; IN VITRO STUDY; IN VIVO STUDY; LUNG LAVAGE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY TRACT INFLAMMATION;

AIRWAY REMODELING; ANIMALS; ASTHMA; BRONCHI; CADHERINS; CURCUMIN; CYTOKINES; DEXAMETHASONE; FEMALE; GLUCOCORTICOIDS; HUMANS; MICE; MICE, INBRED BALB C; PLASMINOGEN ACTIVATOR INHIBITOR 1; PYRAZOLES; RNA, DOUBLE-STRANDED;

MURINAE;

EID: 84860787059     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2012.04.011     Document Type: Article

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