Intra-airway administration of small interfering RNA targeting plasminogen activator inhibitor-1 attenuates allergic asthma in mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 301, Issue 6, 2011, Pages

  Miyamoto, Shintaro ^a   Hattori, Noboru ^a   Senoo, Tadashi ^a   Onari, Yojiro ^a   Iwamoto, Hiroshi ^a   Kanehara, Masashi ^a   Ishikawa, Nobuhisa ^a   Fujitaka, Kazunori ^a   Haruta, Yoshinori ^a   Murai, Hiroshi ^a   Yokoyama, Akihito ^b   Kohno, Nobuoki ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b KOCHI UNIVERSITY   (Japan)

Author keywords

Airway hyperresponsiveness; Airway remodeling; Allergic airway inflammation; Plasminogen activator inhibitors

Indexed keywords

OVALBUMIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA;

ADOLESCENT; ADULT; ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE DURATION; GENE SILENCING; HUMAN; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SCHOOL CHILD; SPUTUM;

AIRWAY REMODELING; ANIMALS; ASTHMA; BRONCHITIS; BRONCHOALVEOLAR LAVAGE FLUID; DRUG EVALUATION, PRECLINICAL; FEMALE; HEPATOCYTE GROWTH FACTOR; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR TARGETED THERAPY; OVALBUMIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; PULMONARY EOSINOPHILIA; RNA INTERFERENCE; RNA, SMALL INTERFERING; SPUTUM;

EID: 82855167217     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00115.2011     Document Type: Article

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