-
1
-
-
0021168136
-
Pathogenesis of serratial infection: activation of the Hageman factor-prekallikrein cascade by serratial protease
-
Matsumoto, K., Yamamoto, T., Kamata, R. and Maeda, H. (1984) Pathogenesis of serratial infection: activation of the Hageman factor-prekallikrein cascade by serratial protease. J. Biochem. 96, 739-749.
-
(1984)
J. Biochem.
, vol.96
, pp. 739-749
-
-
Matsumoto, K.1
Yamamoto, T.2
Kamata, R.3
Maeda, H.4
-
2
-
-
0021847045
-
A serratial protease causes vascular permeability reaction by activation of the Hageman factor-dependent pathway in guinea pigs
-
Kamata, R., Yamamoto, T., Matsumoto, K. and Maeda, H. (1985) A serratial protease causes vascular permeability reaction by activation of the Hageman factor-dependent pathway in guinea pigs. Infect. Immun. 48, 747-753.
-
(1985)
Infect. Immun.
, vol.48
, pp. 747-753
-
-
Kamata, R.1
Yamamoto, T.2
Matsumoto, K.3
Maeda, H.4
-
3
-
-
0024340635
-
Activation of Hageman factor and prekallikrein and generation of kinin by various microbial proteinases
-
Molla, A., Yamamoto, T., Akaike, T., Miyoshi, S. and Maeda, H. (1989) Activation of Hageman factor and prekallikrein and generation of kinin by various microbial proteinases. J. Biol. Chem. 264, 10589-10594.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 10589-10594
-
-
Molla, A.1
Yamamoto, T.2
Akaike, T.3
Miyoshi, S.4
Maeda, H.5
-
4
-
-
0027305768
-
Effect of microbial and mite proteases on low and high molecular weight kininogens
-
Maruo, K., Akaike, T., Inada, Y., Ohkubo, I., Ono, T. and Maeda, H. (1993) Effect of microbial and mite proteases on low and high molecular weight kininogens. J. Biol. Chem. 268, 17711-17715.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 17711-17715
-
-
Maruo, K.1
Akaike, T.2
Inada, Y.3
Ohkubo, I.4
Ono, T.5
Maeda, H.6
-
5
-
-
77952562433
-
Microbial proteinases and pathogenesis of infection
-
(ed. Creighton, T.E.). John Wiley & Sons, New York
-
Maeda, H. (2002) Microbial proteinases and pathogenesis of infection. In The Encyclopedia of Molecular Medicine, vol. 4 (ed. Creighton, T.E.). John Wiley & Sons, New York, pp. 2663-2668.
-
(2002)
The Encyclopedia of Molecular Medicine
, vol.4
, pp. 2663-2668
-
-
Maeda, H.1
-
6
-
-
0029907110
-
Role of microbial proteases in pathogenesis
-
Maeda, H. (1996) Role of microbial proteases in pathogenesis. Microbiol. Immunol. 40, 685-699.
-
(1996)
Microbiol. Immunol.
, vol.40
, pp. 685-699
-
-
Maeda, H.1
-
7
-
-
0023821387
-
3]-bradykinin in ascitic fluid from a patient with gastric cancer
-
3]-bradykinin in ascitic fluid from a patient with gastric cancer. J. Biol. Chem. 263, 16051-16054.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 16051-16054
-
-
Maeda, H.1
Matsumura, Y.2
Kato, H.3
-
8
-
-
0024151625
-
Involvement of the kiningenerating cascade and enhanced vascular permeability in tumor tissue
-
Matsumura, Y., Kimura, M., Yamamoto, T. and Maeda, H. (1988) Involvement of the kiningenerating cascade and enhanced vascular permeability in tumor tissue. Jpn. J. Cancer Res. 79, 1327-1334.
-
(1988)
Jpn. J. Cancer Res.
, vol.79
, pp. 1327-1334
-
-
Matsumura, Y.1
Kimura, M.2
Yamamoto, T.3
Maeda, H.4
-
9
-
-
0025806374
-
Kinin-generating cascade in advanced cancer patients and in vitro study
-
Matsumura, Y., Maruo, K., Kimura, M., Yamamoto, T., Konno, T. and Maeda, H. (1991) Kinin-generating cascade in advanced cancer patients and in vitro study. Jpn. J. Cancer Res. 82, 732-741.
-
(1991)
Jpn. J. Cancer Res.
, vol.82
, pp. 732-741
-
-
Matsumura, Y.1
Maruo, K.2
Kimura, M.3
Yamamoto, T.4
Konno, T.5
Maeda, H.6
-
10
-
-
0032755487
-
Kallikrein-kinin in infection and cancer
-
Maeda, H., Wu, J., Okamoto, T., Maruo, K. and Akaike, T. (1999) Kallikrein-kinin in infection and cancer. Immunopharmacology 43, 115-128.
-
(1999)
Immunopharmacology
, vol.43
, pp. 115-128
-
-
Maeda, H.1
Wu, J.2
Okamoto, T.3
Maruo, K.4
Akaike, T.5
-
11
-
-
0028227005
-
Enhanced vascular permeability in solid tumor is mediated by nitric oxide and inhibited by both new nitric oxide scavenger and nitric oxide synthase inhibitor
-
Maeda, H., Noguchi, Y., Sato, K. and Akaike, T. (1994) Enhanced vascular permeability in solid tumor is mediated by nitric oxide and inhibited by both new nitric oxide scavenger and nitric oxide synthase inhibitor. Jpn. J. Cancer Res. 85, 331-334.
-
(1994)
Jpn. J. Cancer Res.
, vol.85
, pp. 331-334
-
-
Maeda, H.1
Noguchi, Y.2
Sato, K.3
Akaike, T.4
-
12
-
-
0035001708
-
Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinase
-
Wu, J., Akaike, T., Hayashida, K., Okamoto, T., Okuyama, A. and Maeda, H. (2001) Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinase. Jpn. J. Cancer Res. 92, 439-451.
-
(2001)
Jpn. J. Cancer Res.
, vol.92
, pp. 439-451
-
-
Wu, J.1
Akaike, T.2
Hayashida, K.3
Okamoto, T.4
Okuyama, A.5
Maeda, H.6
-
13
-
-
0031964923
-
Modulation of enhanced vascular permeability in tumors by a bradykinin antagonist, a cyclooxygenase inhibitor, and a nitric oxide scavenger
-
Wu, J., Akaike, T. and Maeda, H. (1998) Modulation of enhanced vascular permeability in tumors by a bradykinin antagonist, a cyclooxygenase inhibitor, and a nitric oxide scavenger. Cancer Res. 58, 159-165.
-
(1998)
Cancer Res
, vol.58
, pp. 159-165
-
-
Wu, J.1
Akaike, T.2
Maeda, H.3
-
14
-
-
0031570730
-
Activation of human neutrophil procollagenase by nitrogen dioxide and peroxynitrite: a novel mechanism for procollagenase activation involving nitric oxide
-
Okamoto, T., Akaike, T., Nagano, T., Miyajima, S., Suga, M., Ando, M., Ichimori, K. and Maeda, H. (1997) Activation of human neutrophil procollagenase by nitrogen dioxide and peroxynitrite: a novel mechanism for procollagenase activation involving nitric oxide. Arch. Biochem. Biophys. 342, 261-274.
-
(1997)
Arch. Biochem. Biophys.
, vol.342
, pp. 261-274
-
-
Okamoto, T.1
Akaike, T.2
Nagano, T.3
Miyajima, S.4
Suga, M.5
Ando, M.6
Ichimori, K.7
Maeda, H.8
-
15
-
-
0037334516
-
Vascular permeability enhancement in solid tumor: various factors, mechanisms involved and its implications
-
Maeda, H., Fang, J., Inutsuka, T. and Kitamoto, Y. (2003) Vascular permeability enhancement in solid tumor: various factors, mechanisms involved and its implications. Int. Immunopharmacol. 3, 319-328.
-
(2003)
Int. Immunopharmacol.
, vol.3
, pp. 319-328
-
-
Maeda, H.1
Fang, J.2
Inutsuka, T.3
Kitamoto, Y.4
-
16
-
-
0030175877
-
Bradykinin and nitric oxide in infectious disease and cancer
-
Maeda, H., Akaike, T., Wu, J., Noguchi, Y. and Sakata, Y. (1996) Bradykinin and nitric oxide in infectious disease and cancer. Immunopharmacology 33, 222-230.
-
(1996)
Immunopharmacology
, vol.33
, pp. 222-230
-
-
Maeda, H.1
Akaike, T.2
Wu, J.3
Noguchi, Y.4
Sakata, Y.5
-
17
-
-
0018287715
-
A lipophilic derivative of neocarzinostatin: A polymer conjugation of an antitumor protein antibiotic
-
Maeda, H., Takeshita, J. and Kanamaru, R. (1979) A lipophilic derivative of neocarzinostatin: A polymer conjugation of an antitumor protein antibiotic. Int. J. Pept. Protein Res. 14, 81-87.
-
(1979)
Int. J. Pept. Protein Res.
, vol.14
, pp. 81-87
-
-
Maeda, H.1
Takeshita, J.2
Kanamaru, R.3
-
18
-
-
0021908189
-
Conjugation of poly(styrene-co-maleic acid) derivatives to the antitumor protein neocarzinostatin: Pronounced improvements in pharmacological properties
-
Maeda, H., Ueda, M., Morinaga, T. and Matsumoto, T. (1985) Conjugation of poly(styrene-co-maleic acid) derivatives to the antitumor protein neocarzinostatin: Pronounced improvements in pharmacological properties. J. Med. Chem. 28, 455-461.
-
(1985)
J. Med. Chem.
, vol.28
, pp. 455-461
-
-
Maeda, H.1
Ueda, M.2
Morinaga, T.3
Matsumoto, T.4
-
19
-
-
0021349643
-
Use of oily contrast medium for selective drug targeting to tumor: enhanced therapeutic effect and X-ray image
-
Iwai, K., Maeda, H. and Konno, T. (1984) Use of oily contrast medium for selective drug targeting to tumor: enhanced therapeutic effect and X-ray image. Cancer Res. 44, 2115-2121.
-
(1984)
Cancer Res
, vol.44
, pp. 2115-2121
-
-
Iwai, K.1
Maeda, H.2
Konno, T.3
-
20
-
-
0023280718
-
Tumor targeting by arterial administration of lipids: rabbit model with VX2 carcinoma in the liver
-
Iwai, K., Maeda, H., Konno, T., Matsumura, Y., Yamashita, R., Yamasaki, K., Hirayama, S. and Miyauchi, Y. (1987) Tumor targeting by arterial administration of lipids: rabbit model with VX2 carcinoma in the liver. Anticancer Res. 7, 321-328.
-
(1987)
Anticancer Res
, vol.7
, pp. 321-328
-
-
Iwai, K.1
Maeda, H.2
Konno, T.3
Matsumura, Y.4
Yamashita, R.5
Yamasaki, K.6
Hirayama, S.7
Miyauchi, Y.8
-
21
-
-
0002289558
-
The origin of lipoproteins in lymph
-
(ed. Mayerson). Charles C Thomas Publisher, Springfield, IL
-
Courtice, F.C. (1996) The origin of lipoproteins in lymph. In Lymph and Lymphatic System (ed. Mayerson). Charles C Thomas Publisher, Springfield, IL, pp. 89-126.
-
(1996)
Lymph and Lymphatic System
, pp. 89-126
-
-
Courtice, F.C.1
-
22
-
-
0018889386
-
Lymphotropic accumulation of an antitumor antibiotic protein, neocarzinostatin
-
Maeda, H., Takeshita, J. and Yamashita, A. (1980) Lymphotropic accumulation of an antitumor antibiotic protein, neocarzinostatin. Eur. J. Cancer 16, 723-731.
-
(1980)
Eur. J. Cancer
, vol.16
, pp. 723-731
-
-
Maeda, H.1
Takeshita, J.2
Yamashita, A.3
-
23
-
-
0019948596
-
In vitro mode of action, pharmacokinetics, and organ specificity of poly (maleic acid-styrene)-conjugated neocarzinostatin
-
Takeshita, J., Maeda, H. and Kanamaru, R. (1982) In vitro mode of action, pharmacokinetics, and organ specificity of poly (maleic acid-styrene)-conjugated neocarzinostatin, SMANCS. Gann 73, 278-284.
-
(1982)
SMANCS. Gann
, vol.73
, pp. 278-284
-
-
Takeshita, J.1
Maeda, H.2
Kanamaru, R.3
-
24
-
-
0020525867
-
Effect of arterial administration of high-molecular-weight anticancer agent SMANCS with lipid lymphographic agent on hepatoma: a preliminary report
-
Konno, T., Maeda, H., Iwai, K., Tashiro, S., Maki, S., Morinaga, T., Mochinaga, M., Hiraoka, T. and Yokoyama, I. (1983) Effect of arterial administration of high-molecular-weight anticancer agent SMANCS with lipid lymphographic agent on hepatoma: a preliminary report. Eur. J. Cancer Clin. Oncol. 19, 1053-1065.
-
(1983)
Eur. J. Cancer Clin. Oncol.
, vol.19
, pp. 1053-1065
-
-
Konno, T.1
Maeda, H.2
Iwai, K.3
Tashiro, S.4
Maki, S.5
Morinaga, T.6
Mochinaga, M.7
Hiraoka, T.8
Yokoyama, I.9
-
25
-
-
0021687244
-
Selective targeting of anticancer drug and simultaneous image enhancement in solid tumors by arterially administered lipid contrast medium
-
Konno, T., Maeda, H., Iwai, K., Maki, S., Tashiro, S., Uchida, M. and Miyauchi, Y. (1984) Selective targeting of anticancer drug and simultaneous image enhancement in solid tumors by arterially administered lipid contrast medium. Cancer 54, 2367-2374.
-
(1984)
Cancer
, vol.54
, pp. 2367-2374
-
-
Konno, T.1
Maeda, H.2
Iwai, K.3
Maki, S.4
Tashiro, S.5
Uchida, M.6
Miyauchi, Y.7
-
26
-
-
0021968171
-
Image enhancement in computerized tomography for sensitive diagnosis of liver cancer and semiquantitation of tumor selective drug targeting with oily contrast medium
-
Maki, S., Konno, T. and Maeda, H. (1985) Image enhancement in computerized tomography for sensitive diagnosis of liver cancer and semiquantitation of tumor selective drug targeting with oily contrast medium. Cancer 56, 751-757.
-
(1985)
Cancer
, vol.56
, pp. 751-757
-
-
Maki, S.1
Konno, T.2
Maeda, H.3
-
27
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS
-
Matsumura, Y. and Maeda, H. (1986) A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS. Cancer Res. 46, 6387-6392.
-
(1986)
Cancer Res
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
28
-
-
0031959490
-
Early phase tumor accumulation of macromolecules: a great difference in clearance rate between tumor and normal tissues
-
Noguchi, Y., Wu, J., Duncan, R., Strohalm, J., Ulbrich, K., Akaike, T. and Maeda, H. (1998) Early phase tumor accumulation of macromolecules: a great difference in clearance rate between tumor and normal tissues. Jpn. J. Cancer Res. 89, 307-314.
-
(1998)
Jpn. J. Cancer Res.
, vol.89
, pp. 307-314
-
-
Noguchi, Y.1
Wu, J.2
Duncan, R.3
Strohalm, J.4
Ulbrich, K.5
Akaike, T.6
Maeda, H.7
-
29
-
-
0029039418
-
Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier
-
Seymour, L.W., Miyamoto, Y., Maeda, H., Brereton, M., Strohalm, J., Ulbrich, K. and Duncan, R. (1995) Influence of molecular weight on passive tumour accumulation of a soluble macromolecular drug carrier. Eur. J. Cancer 31, 766-770.
-
(1995)
Eur. J. Cancer
, vol.31
, pp. 766-770
-
-
Seymour, L.W.1
Miyamoto, Y.2
Maeda, H.3
Brereton, M.4
Strohalm, J.5
Ulbrich, K.6
Duncan, R.7
-
30
-
-
0034000453
-
Tumor vascular permeability and the EPR effect in macromolecular therapeutics
-
Maeda, H., Wu, J., Sawa, T., Matsumura, Y. and Hori, K. (2000) Tumor vascular permeability and the EPR effect in macromolecular therapeutics. J. Control. Release 65, 271-284.
-
(2000)
J. Control. Release
, vol.65
, pp. 271-284
-
-
Maeda, H.1
Wu, J.2
Sawa, T.3
Matsumura, Y.4
Hori, K.5
-
31
-
-
0035816204
-
Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS
-
Maeda, H., Sawa, T. and Konno, T. (2001) Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS. J. Control. Release 74, 47-61.
-
(2001)
J. Control. Release
, vol.74
, pp. 47-61
-
-
Maeda, H.1
Sawa, T.2
Konno, T.3
-
32
-
-
0034993240
-
The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting
-
Maeda, H. (2001) The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv. Enzyme Regul. 41, 189-207.
-
(2001)
Adv. Enzyme Regul.
, vol.41
, pp. 189-207
-
-
Maeda, H.1
-
33
-
-
0024839642
-
Tumoritropic and lymphotropic principles of macromolecular drugs
-
Maeda, H. and Matsumura, Y. (1989) Tumoritropic and lymphotropic principles of macromolecular drugs. Crit. Rev. Ther. Drug Carrier Syst. 6, 193-210.
-
(1989)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.6
, pp. 193-210
-
-
Maeda, H.1
Matsumura, Y.2
-
34
-
-
60749108001
-
Polymeric drugs and nanomedicines for efficient tumor targeted drug delivery based on EPReffect
-
Maeda, H., Bharate, G.Y. and Daruwalla, J. (2009) Polymeric drugs and nanomedicines for efficient tumor targeted drug delivery based on EPReffect. Eur. J. Pharm. Biopharm. 71, 409-419.
-
(2009)
Eur. J. Pharm. Biopharm.
, vol.71
, pp. 409-419
-
-
Maeda, H.1
Bharate, G.Y.2
Daruwalla, J.3
-
35
-
-
77952575335
-
Tumor-selective delivery of macromolecular drugs via the EPR effect: background and future prospects
-
Maeda, H. (2010) Tumor-selective delivery of macromolecular drugs via the EPR effect: background and future prospects. Bioconjug. Chem. 21, 797-802.
-
(2010)
Bioconjug. Chem.
, vol.21
, pp. 797-802
-
-
Maeda, H.1
-
36
-
-
84869501324
-
The EPR-effect in relation to tumor targeting
-
(eds. Kratz, F., Senter, P. and Steinhagen, H.). Wiley-VCH Verlag GmbH & Co. KG, Weinheim, Germany
-
Maeda, H. (2011) The EPR-effect in relation to tumor targeting. In Drug Delivery in Oncology. From Basic Research to Cancer Therapy (eds. Kratz, F., Senter, P. and Steinhagen, H.). Wiley-VCH Verlag GmbH & Co. KG, Weinheim, Germany, pp. 65-86.
-
(2011)
Drug Delivery in Oncology. From Basic Research to Cancer Therapy
, pp. 65-86
-
-
Maeda, H.1
-
37
-
-
0018888153
-
Selective localization and growth of Bifidobacterium bifidum in mouse tumors following intravenous administration
-
Kimura, N., Taniguchi, S., Aoki, K. and Baba, T. (1980) Selective localization and growth of Bifidobacterium bifidum in mouse tumors following intravenous administration. Cancer Res. 40, 2061-2068.
-
(1980)
Cancer Res
, vol.40
, pp. 2061-2068
-
-
Kimura, N.1
Taniguchi, S.2
Aoki, K.3
Baba, T.4
-
38
-
-
14144251067
-
Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium
-
Zhao, M., Yang, M., Li, X.M., Jiang, P., Baranov, E., Li, S., Xu, M., Penman, S. and Hoffman, R.M. (2005) Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium. Proc. Natl. Acad. Sci. U.S.A. 102, 755-760.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 755-760
-
-
Zhao, M.1
Yang, M.2
Li, X.M.3
Jiang, P.4
Baranov, E.5
Li, S.6
Xu, M.7
Penman, S.8
Hoffman, R.M.9
-
39
-
-
69249212582
-
Tumor-targeting amino acid auxotrophic Salmonella typhimurium
-
Hoffman, R.M. (2009) Tumor-targeting amino acid auxotrophic Salmonella typhimurium. Amino Acids 37, 509-521.
-
(2009)
Amino Acids
, vol.37
, pp. 509-521
-
-
Hoffman, R.M.1
-
40
-
-
0029551759
-
Microvascular corrosion casting in the study of tumor vascularity: a review
-
Konerding, M.A., Miodonski, A.J. and Lametschwandtner, A. (1995) Microvascular corrosion casting in the study of tumor vascularity: a review. Scanning Microsc. 9, 1233-1244.
-
(1995)
Scanning Microsc
, vol.9
, pp. 1233-1244
-
-
Konerding, M.A.1
Miodonski, A.J.2
Lametschwandtner, A.3
-
41
-
-
0033839080
-
Openings between defective endothelial cells explain tumor vessel leakiness
-
Hashizume, H., Baluk, P., Morikawa, S., McLean, J.W., Thurston, G., Roberge, S., Jain, R.K. and McDonald, D.M. (2000) Openings between defective endothelial cells explain tumor vessel leakiness. Am. J. Pathol. 1561, 1363-1380.
-
(2000)
Am. J. Pathol.
, vol.1561
, pp. 1363-1380
-
-
Hashizume, H.1
Baluk, P.2
Morikawa, S.3
McLean, J.W.4
Thurston, G.5
Roberge, S.6
Jain, R.K.7
McDonald, D.M.8
-
42
-
-
0025255160
-
Microvascular architecture of experimental colon tumors in the rat
-
Skinner, S.A., Tutton, P.J. and O'Brien, P.E. (1990) Microvascular architecture of experimental colon tumors in the rat. Cancer Res. 50, 2411-2417.
-
(1990)
Cancer Res
, vol.50
, pp. 2411-2417
-
-
Skinner, S.A.1
Tutton, P.J.2
O'Brien, P.E.3
-
43
-
-
0034906627
-
Combretastatin A4 prodrug study of effect on the growth and the microvasculature of colorectal liver metastases in a murine model
-
Malcontenti-Wilson, C., Muralidharan, V., Skinner, S., Christophi, C., Sherris, D. and O'Brien, P.E. (2001) Combretastatin A4 prodrug study of effect on the growth and the microvasculature of colorectal liver metastases in a murine model. Clin. Cancer Res. 7, 1052-1060.
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 1052-1060
-
-
Malcontenti-Wilson, C.1
Muralidharan, V.2
Skinner, S.3
Christophi, C.4
Sherris, D.5
O'Brien, P.E.6
-
44
-
-
77954837315
-
In vitro and in vivo evaluation of tumor targeting styrenemaleic acid-pirarubicin micelles: survival improvement and inhibition of liver metastases
-
Daruwalla, J., Nikfarjam, M., Greish, K., Malcontenti-Wilson, C., Muralidharan, V., Christophi, C. and Maeda, H. (2010) In vitro and in vivo evaluation of tumor targeting styrenemaleic acid-pirarubicin micelles: survival improvement and inhibition of liver metastases. Cancer Sci. 101, 1866-1874.
-
(2010)
Cancer Sci
, vol.101
, pp. 1866-1874
-
-
Daruwalla, J.1
Nikfarjam, M.2
Greish, K.3
Malcontenti-Wilson, C.4
Muralidharan, V.5
Christophi, C.6
Maeda, H.7
-
45
-
-
85013312416
-
Tumor angiogenesis: therapeutic implications
-
Folkman, J. (1971) Tumor angiogenesis: therapeutic implications. N. Engl. J. Med. 285, 1182-1186.
-
(1971)
N. Engl. J. Med.
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
46
-
-
0025141337
-
What is the evidence that tumors are angiogenesis dependent?
-
Folkman, J. (1990) What is the evidence that tumors are angiogenesis dependent? J. Natl. Cancer Inst. 82, 4-6.
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 4-6
-
-
Folkman, J.1
-
47
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
Folkman, J. (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1, 27-31.
-
(1995)
Nat. Med.
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
48
-
-
0021111648
-
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid
-
Senger, D.R., Galli, S.J., Dvorak, A.M., Perruzzi, C.A., Harvey, V.S. and Dvorak, H.F. (1983) Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219, 983-985.
-
(1983)
Science
, vol.219
, pp. 983-985
-
-
Senger, D.R.1
Galli, S.J.2
Dvorak, A.M.3
Perruzzi, C.A.4
Harvey, V.S.5
Dvorak, H.F.6
-
49
-
-
0023788067
-
Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules
-
Dvorak, H.F., Nagy, J.A., Dvorak, J.T. and Dvorak, A.M. (1988) Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules. Am. J. Pathol. 133, 95-109.
-
(1988)
Am. J. Pathol.
, vol.133
, pp. 95-109
-
-
Dvorak, H.F.1
Nagy, J.A.2
Dvorak, J.T.3
Dvorak, A.M.4
-
50
-
-
0029004025
-
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
-
Dvorak, H.F., Brown, L.F., Detmar, M. and Dvorak, A.M. (1995) Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am. J. Pathol. 146, 1029-1039.
-
(1995)
Am. J. Pathol.
, vol.146
, pp. 1029-1039
-
-
Dvorak, H.F.1
Brown, L.F.2
Detmar, M.3
Dvorak, A.M.4
-
51
-
-
0024818355
-
Vascular endothelial growth factor is a secreted angiogenic mitogen
-
Leung, D.W., Cachianes, G., Kuang, W.J., Goeddel, D.V. and Ferrara, N. (1989) Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246, 1306-1309.
-
(1989)
Science
, vol.246
, pp. 1306-1309
-
-
Leung, D.W.1
Cachianes, G.2
Kuang, W.J.3
Goeddel, D.V.4
Ferrara, N.5
-
52
-
-
0028145249
-
Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model
-
Miller, J.W., Adamis, A.P., Shima, D.T., D'Amore, P.A., Moulton, R.S., O'Reilly, M.S., Folkman, J., Dvorak, H.F., Brown, L.F., Berse, B., Yeo, T.K. and Yeo, K.T. (1994) Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model. Am. J. Pathol. 145, 574-584.
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 574-584
-
-
Miller, J.W.1
Adamis, A.P.2
Shima, D.T.3
D'Amore, P.A.4
Moulton, R.S.5
O'Reilly, M.S.6
Folkman, J.7
Dvorak, H.F.8
Brown, L.F.9
Berse, B.10
Yeo, T.K.11
Yeo, K.T.12
-
53
-
-
0032889698
-
Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis
-
Dvorak, H.F., Nagy, J.A., Feng, D., Brown, L.F. and Dvorak, A.M. (1999) Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis. Curr. Top. Microbiol. Immunol. 237, 97-132.
-
(1999)
Curr. Top. Microbiol. Immunol.
, vol.237
, pp. 97-132
-
-
Dvorak, H.F.1
Nagy, J.A.2
Feng, D.3
Brown, L.F.4
Dvorak, A.M.5
-
54
-
-
0024375781
-
Oxygen radicals in influenza-induced pathogenesis and treatment with pyran polymer-conjugated SOD
-
Oda, T., Akaike, T., Hamamoto, T., Suzuki, F., Hirano, T. and Maeda, H. (1989) Oxygen radicals in influenza-induced pathogenesis and treatment with pyran polymer-conjugated SOD. Science 244, 974-976.
-
(1989)
Science
, vol.244
, pp. 974-976
-
-
Oda, T.1
Akaike, T.2
Hamamoto, T.3
Suzuki, F.4
Hirano, T.5
Maeda, H.6
-
55
-
-
0025193910
-
- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice
-
- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice. J. Clin. Invest. 85, 739-745.
-
(1990)
J. Clin. Invest.
, vol.85
, pp. 739-745
-
-
Akaike, T.1
Ando, M.2
Oda, T.3
Doi, T.4
Ijiri, S.5
Araki, S.6
Maeda, H.7
-
56
-
-
0026050165
-
Oxygen free radicals as pathogenic molecules in viral diseases
-
Maeda, H. and Akaike, T. (1991) Oxygen free radicals as pathogenic molecules in viral diseases. Proc. Soc. Exp. Biol. Med. 198, 721-727.
-
(1991)
Proc. Soc. Exp. Biol. Med.
, vol.198
, pp. 721-727
-
-
Maeda, H.1
Akaike, T.2
-
57
-
-
0029958972
-
Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals
-
Akaike, T., Noguchi, Y., Ijiri, S., Setoguchi, K., Suga, M., Zheng, Y.M., Dietzschold, B. and Maeda, H. (1996) Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals. Proc. Natl. Acad. Sci. U.S.A. 93, 2448-2453.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 2448-2453
-
-
Akaike, T.1
Noguchi, Y.2
Ijiri, S.3
Setoguchi, K.4
Suga, M.5
Zheng, Y.M.6
Dietzschold, B.7
Maeda, H.8
-
58
-
-
17544375439
-
Viral mutation accelerated by nitric oxide production during infection in vivo
-
Akaike, T., Fujii, S., Kato, A., Yoshitake, J., Miyamoto, Y., Sawa, T., Okamoto, S., Suga, M., Asakawa, M., Nagai, Y. and Maeda, H. (2000) Viral mutation accelerated by nitric oxide production during infection in vivo. FASEB J. 14, 1447-1454.
-
(2000)
FASEB J
, vol.14
, pp. 1447-1454
-
-
Akaike, T.1
Fujii, S.2
Kato, A.3
Yoshitake, J.4
Miyamoto, Y.5
Sawa, T.6
Okamoto, S.7
Suga, M.8
Asakawa, M.9
Nagai, Y.10
Maeda, H.11
-
59
-
-
0002217831
-
Pathophysiological effects of high-output production of nitric oxide
-
(ed. Ignarro, L.J.). Academic Press, San Diego
-
Akaike, T. and Maeda, H. (2000) Pathophysiological effects of high-output production of nitric oxide. In Nitric Oxide (ed. Ignarro, L.J.). Academic Press, San Diego, pp. 733-745.
-
(2000)
Nitric Oxide
, pp. 733-745
-
-
Akaike, T.1
Maeda, H.2
-
60
-
-
0031983652
-
Free radicals in viral pathogenesis: molecular mechanisms involving superoxide and NO
-
Akaike, T., Suga, M. and Maeda, H. (1998) Free radicals in viral pathogenesis: molecular mechanisms involving superoxide and NO. Proc. Soc. Exp. Biol. Med. 217, 64-73.
-
(1998)
Proc. Soc. Exp. Biol. Med.
, vol.217
, pp. 64-73
-
-
Akaike, T.1
Suga, M.2
Maeda, H.3
-
61
-
-
0030915245
-
Induction of nitric oxide synthesis and xanthine oxidase and their role in the antimicrobial mechanism against Salmonella typhimurium in mice
-
Umezawa, K., Akaike, T., Fujii, S., Suga, M., Setoguchi, K., Ozawa, A. and Maeda, H. (1997) Induction of nitric oxide synthesis and xanthine oxidase and their role in the antimicrobial mechanism against Salmonella typhimurium in mice. Infect. Immun. 65, 2932-2940.
-
(1997)
Infect. Immun.
, vol.65
, pp. 2932-2940
-
-
Umezawa, K.1
Akaike, T.2
Fujii, S.3
Suga, M.4
Setoguchi, K.5
Ozawa, A.6
Maeda, H.7
-
62
-
-
3543111961
-
Nitric oxide as an endogenous mutagen for Sendai virus without antiviral activity
-
Yoshitake, J., Akaike, T., Akuta, T., Tamura, F., Ogura, T., Esumi, H. and Maeda, H. (2004) Nitric oxide as an endogenous mutagen for Sendai virus without antiviral activity. J. Virol. 78, 8709-8719.
-
(2004)
J. Virol.
, vol.78
, pp. 8709-8719
-
-
Yoshitake, J.1
Akaike, T.2
Akuta, T.3
Tamura, F.4
Ogura, T.5
Esumi, H.6
Maeda, H.7
-
63
-
-
0029998870
-
Excessive production of nitric oxide in rat solid tumor and its implication in rapid tumor growth
-
Doi, K., Akaike, T., Horie, H., Noguchi, Y., Fujii, S., Beppu, T., Ogawa, M. and Maeda, H. (1996) Excessive production of nitric oxide in rat solid tumor and its implication in rapid tumor growth. Cancer 77, 1598-1604.
-
(1996)
Cancer
, vol.77
, pp. 1598-1604
-
-
Doi, K.1
Akaike, T.2
Horie, H.3
Noguchi, Y.4
Fujii, S.5
Beppu, T.6
Ogawa, M.7
Maeda, H.8
-
64
-
-
3142581964
-
Antioxidative and antimutagenic activities of 4-vinyl-2,6-dimethoxyphenol (canolol) isolated from canola oil
-
Kuwahara, H., Kanazawa, A., Wakamatsu, D., Morimura, S., Kida, K., Akaike, T. and Maeda, H. (2004) Antioxidative and antimutagenic activities of 4-vinyl-2,6-dimethoxyphenol (canolol) isolated from canola oil. J. Agric. Food Chem. 52, 4380-4387.
-
(2004)
J. Agric. Food Chem.
, vol.52
, pp. 4380-4387
-
-
Kuwahara, H.1
Kanazawa, A.2
Wakamatsu, D.3
Morimura, S.4
Kida, K.5
Akaike, T.6
Maeda, H.7
-
65
-
-
61749098693
-
Generation of drug-resistant mutants of Helicobacter pylori in the presence of peroxynitrite, a derivative of nitric oxide at pathophysiological concentration
-
Kuwahara, H., Kariu, T., Fang, J. and Maeda, H. (2009) Generation of drug-resistant mutants of Helicobacter pylori in the presence of peroxynitrite, a derivative of nitric oxide at pathophysiological concentration. Microbiol. Immunol. 53, 1-7.
-
(2009)
Microbiol. Immunol.
, vol.53
, pp. 1-7
-
-
Kuwahara, H.1
Kariu, T.2
Fang, J.3
Maeda, H.4
-
66
-
-
31544453292
-
Nitrative DNA damage in inflammation and its possible role in carcinogenesis
-
Sawa, T. and Oshima, H. (2006) Nitrative DNA damage in inflammation and its possible role in carcinogenesis. Nitric Oxide 14, 91-100.
-
(2006)
Nitric Oxide
, vol.14
, pp. 91-100
-
-
Sawa, T.1
Oshima, H.2
-
67
-
-
31544432817
-
Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: structures and mechanisms of product formation
-
Niles, J.C., Wishnok, J.S. and Tannenbaum, S.R. (2006) Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: structures and mechanisms of product formation. Nitric Oxide 14, 109-121.
-
(2006)
Nitric Oxide
, vol.14
, pp. 109-121
-
-
Niles, J.C.1
Wishnok, J.S.2
Tannenbaum, S.R.3
-
69
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
Sjöblom, T., Jones, S., Wood, L., Parsons, D.W., Lin, J., Barber, T.D., Mandelker, D., Leary, R.J., Ptak, J., Silliman, N., Szabo, S., Buckhaults, P., Farrell, C., Meeh, P., Markowitz, S.D., Willis, J., Dawson, D., Willson, J.K.V., Gazdar, A.F., Hartigan, J., Wu, L., Liu, C., Parmigiani, G., Park, B.H., Bachman, K.E., Papadopoulos, N., Vogelstein, B., Kinzler, K.W. and Velculescu, V.E. (2006) The consensus coding sequences of human breast and colorectal cancers. Science 314, 268-274.
-
(2006)
Science
, vol.314
, pp. 268-274
-
-
Sjöblom, T.1
Jones, S.2
Wood, L.3
Parsons, D.W.4
Lin, J.5
Barber, T.D.6
Mandelker, D.7
Leary, R.J.8
Ptak, J.9
Silliman, N.10
Szabo, S.11
Buckhaults, P.12
Farrell, C.13
Meeh, P.14
Markowitz, S.D.15
Willis, J.16
Dawson, D.17
Willson, J.K.V.18
Gazdar, A.F.19
Hartigan, J.20
Wu, L.21
Liu, C.22
Parmigiani, G.23
Park, B.H.24
Bachman, K.E.25
Papadopoulos, N.26
Vogelstein, B.27
Kinzler, K.W.28
Velculescu, V.E.29
more..
-
70
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
Wood, L.D., Parsons, D.W., Jones, S., Lin, J., Sjöblom, T., Leary, R.J., Shen, D., Boca, S.M., Barber, T., Ptak, J., Silliman, N., Szabo, S., Dezso, Z., Ustyanksky, V., Nikolskaya, T., Nikolsky, Y., Karchin, R., Wilson, P.A., Kaminker, J.S., Zhang, Z., Croshaw, R., Willis, J., Dawson, D., Shipitsin, M., Willson, J.K.V., Sukumar, S., Polyak, K., Park, B.H., Pethiyagoda, C.L., Pant, P.V.K., Ballinger, D.G., Sparks, A.B., Hartigan, J., Smith, D.R., Suh, E., Papadopoulos, N., Buckhaults, P., Markowitz, S.D., Parmigiani, G., Kinzler, K.W., Velculescu, V.E. and Vogelstein, B. (2007) The genomic landscapes of human breast and colorectal cancers. Science 318, 1108-1113.
-
(2007)
Science
, vol.318
, pp. 1108-1113
-
-
Wood, L.D.1
Parsons, D.W.2
Jones, S.3
Lin, J.4
Sjöblom, T.5
Leary, R.J.6
Shen, D.7
Boca, S.M.8
Barber, T.9
Ptak, J.10
Silliman, N.11
Szabo, S.12
Dezso, Z.13
Ustyanksky, V.14
Nikolskaya, T.15
Nikolsky, Y.16
Karchin, R.17
Wilson, P.A.18
Kaminker, J.S.19
Zhang, Z.20
Croshaw, R.21
Willis, J.22
Dawson, D.23
Shipitsin, M.24
Willson, J.K.V.25
Sukumar, S.26
Polyak, K.27
Park, B.H.28
Pethiyagoda, C.L.29
Pant, P.V.K.30
Ballinger, D.G.31
Sparks, A.B.32
Hartigan, J.33
Smith, D.R.34
Suh, E.35
Papadopoulos, N.36
Buckhaults, P.37
Markowitz, S.D.38
Parmigiani, G.39
Kinzler, K.W.40
Velculescu, V.E.41
Vogelstein, B.42
more..
-
71
-
-
70349969478
-
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
-
Shah, S.P., Morin, R.D., Khattra, J., Prentice, L., Pugh, T., Burleigh, A., Delaney, A., Gelmon, K., Guliany, R., Senz, J., Steidl, C., Holt, R.A., Jones, S., Sun, M., Leung, G., Moore, R., Severson, T., Taylor, G.A., Teschendorff, A.E., Tse, K., Turashvili, G., Varhol, R., Warren, R.L., Watson, P., Zhao, Y., Caldas, C., Huntsman, D., Hirst, M., Marra, M.A. and Aparicio, S. (2009) Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature 461, 809-813.
-
(2009)
Nature
, vol.461
, pp. 809-813
-
-
Shah, S.P.1
Morin, R.D.2
Khattra, J.3
Prentice, L.4
Pugh, T.5
Burleigh, A.6
Delaney, A.7
Gelmon, K.8
Guliany, R.9
Senz, J.10
Steidl, C.11
Holt, R.A.12
Jones, S.13
Sun, M.14
Leung, G.15
Moore, R.16
Severson, T.17
Taylor, G.A.18
Teschendorff, A.E.19
Tse, K.20
Turashvili, G.21
Varhol, R.22
Warren, R.L.23
Watson, P.24
Zhao, Y.25
Caldas, C.26
Huntsman, D.27
Hirst, M.28
Marra, M.A.29
Aparicio, S.30
more..
-
72
-
-
68249134187
-
How much is life worth: cetuximab, non-small cell lung cancer, and the $440 billion question
-
Fojo, T. and Grady, C. (2009) How much is life worth: cetuximab, non-small cell lung cancer, and the $440 billion question. J. Natl. Cancer Inst. 101, 1044-1048.
-
(2009)
J. Natl. Cancer Inst.
, vol.101
, pp. 1044-1048
-
-
Fojo, T.1
Grady, C.2
-
73
-
-
59749089432
-
Targeted therapy for advanced colorectal cancer-more is not always better
-
Mayer, R. (2009) Targeted therapy for advanced colorectal cancer-more is not always better. N. Engl. J. Med. 360, 623-625.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 623-625
-
-
Mayer, R.1
-
74
-
-
49849096922
-
Welcome clinical leadership at NICE
-
Anonymous
-
Anonymous (2008) Welcome clinical leadership at NICE. Lancet 372, 601.
-
(2008)
Lancet
, vol.372
, pp. 601
-
-
-
75
-
-
59749091477
-
Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
-
Tol, J., Koopman, M., Cats, A., Rodenburg, C.J., Creemers, G.J.M., Schrama, J.G., Erdkamp, F.L.G., Vos, A.H., van Groeningen, C.J., Sinnige, H.A.M., Richel, D.J., Voest, E.E., Dijkstra, J.R., Vink-Börger, M.E., Antonini, N.F., Mol, L., van Krieken, J.H.J.M., Dalesio, O. and Punt, C.J.A. (2009) Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N. Engl. J. Med. 360, 563-572.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 563-572
-
-
Tol, J.1
Koopman, M.2
Cats, A.3
Rodenburg, C.J.4
Creemers, G.J.M.5
Schrama, J.G.6
Erdkamp, F.L.G.7
Vos, A.H.8
van Groeningen, C.J.9
Sinnige, H.A.M.10
Richel, D.J.11
Voest, E.E.12
Dijkstra, J.R.13
Vink-Börger, M.E.14
Antonini, N.F.15
Mol, L.16
van Krieken, J.H.J.M.17
Dalesio, O.18
Punt, C.J.A.19
-
76
-
-
33847635618
-
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-β signaling
-
Kano, M.R., Bae, Y., Iwata, C., Morishita, Y., Yashiro, M., Oka, M., Fujii, T., Komuro, A., Kiyono, K., Kaminishi, M., Hirakawa, K., Ouchi, Y., Nishiyama, N., Kataoka, K. and Miyazono, K. (2007) Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-β signaling. Proc. Natl. Acad. Sci. U.S.A. 104, 3460-3465.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 3460-3465
-
-
Kano, M.R.1
Bae, Y.2
Iwata, C.3
Morishita, Y.4
Yashiro, M.5
Oka, M.6
Fujii, T.7
Komuro, A.8
Kiyono, K.9
Kaminishi, M.10
Hirakawa, K.11
Ouchi, Y.12
Nishiyama, N.13
Kataoka, K.14
Miyazono, K.15
-
77
-
-
0034306969
-
Blockade of nuclear factor-κB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8
-
Huang, S., Robinson, J.B., Deguzman, A., Bucana, C.D. and Fidler, I.J. (2000) Blockade of nuclear factor-κB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8. Cancer Res. 60, 5334-5339.
-
(2000)
Cancer Res
, vol.60
, pp. 5334-5339
-
-
Huang, S.1
Robinson, J.B.2
Deguzman, A.3
Bucana, C.D.4
Fidler, I.J.5
-
78
-
-
0037732561
-
2 analogue beraprost sodium
-
2 analogue beraprost sodium. J. Drug Target. 11, 45-52.
-
(2003)
J. Drug Target.
, vol.11
, pp. 45-52
-
-
Tanaka, S.1
Akaike, T.2
Wu, J.3
Fang, J.4
Sawa, T.5
Ogawa, M.6
Beppu, T.7
Maeda, H.8
-
79
-
-
0032778341
-
Induction of haem oxygenase-1 by nitric oxide and ischaemia in experimental solid tumours and implications for tumour growth
-
Doi, K., Akaike, T., Fujii, S., Tanaka, S., Ikebe, N., Beppu, T., Shibahara, S., Ogawa, M. and Maeda, H. (1999) Induction of haem oxygenase-1 by nitric oxide and ischaemia in experimental solid tumours and implications for tumour growth. Br. J. Cancer 80, 1945-1954.
-
(1999)
Br. J. Cancer
, vol.80
, pp. 1945-1954
-
-
Doi, K.1
Akaike, T.2
Fujii, S.3
Tanaka, S.4
Ikebe, N.5
Beppu, T.6
Shibahara, S.7
Ogawa, M.8
Maeda, H.9
-
80
-
-
84874098069
-
Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and retention (EPR) effect of solid tumor
-
(in press available online, Jan. 2012)
-
Fang, J., Qin, H., Nakamura, H., Tsukigawa, K. and Maeda, H. (2012) Carbon monoxide, generated by heme oxygenase-1, mediates the enhanced permeability and retention (EPR) effect of solid tumor. Cancer Sci. 103 (in press available online, Jan. 2012).
-
(2012)
Cancer Sci
, vol.103
-
-
Fang, J.1
Qin, H.2
Nakamura, H.3
Tsukigawa, K.4
Maeda, H.5
-
81
-
-
0036740180
-
Pegylated zinc protoporphyrin: a water-soluble heme oxygenase inhibitor with tumor-targeting capacity
-
Sahoo, S.K., Sawa, T., Fang, J., Tanaka, S., Miyamoto, Y., Akaike, T. and Maeda, H. (2002) Pegylated zinc protoporphyrin: a water-soluble heme oxygenase inhibitor with tumor-targeting capacity. Bioconjug. Chem. 13, 1031-1038.
-
(2002)
Bioconjug. Chem.
, vol.13
, pp. 1031-1038
-
-
Sahoo, S.K.1
Sawa, T.2
Fang, J.3
Tanaka, S.4
Miyamoto, Y.5
Akaike, T.6
Maeda, H.7
-
82
-
-
0038418359
-
In vivo antitumor activity of pegylated zinc protoporphyrin: targeted inhibition of heme oxygenase in solid tumor
-
Fang, J., Sawa, T., Akaike, T., Akuta, T., Greish, K., Hamada, A. and Maeda, H. (2003) In vivo antitumor activity of pegylated zinc protoporphyrin: targeted inhibition of heme oxygenase in solid tumor. Cancer Res. 63, 3567-3574.
-
(2003)
Cancer Res
, vol.63
, pp. 3567-3574
-
-
Fang, J.1
Sawa, T.2
Akaike, T.3
Akuta, T.4
Greish, K.5
Hamada, A.6
Maeda, H.7
-
83
-
-
1442326158
-
Antiapoptotic role of heme oxygenase and its potential as an anticancer target
-
Fang, J., Akaike, T. and Maeda, H. (2004) Antiapoptotic role of heme oxygenase and its potential as an anticancer target. Apoptosis 9, 27-35.
-
(2004)
Apoptosis
, vol.9
, pp. 27-35
-
-
Fang, J.1
Akaike, T.2
Maeda, H.3
-
84
-
-
54449095986
-
Styrene maleic acid-pirarubicin disrupts tumor microcirculation and enhances the permeability of colorectal liver metastases
-
Daruwalla, J., Greish, K., Wilson, C.M., Muralidharan, V., Iyer, A., Maeda, H. and Christophi, C. (2009) Styrene maleic acid-pirarubicin disrupts tumor microcirculation and enhances the permeability of colorectal liver metastases. J. Vasc. Res. 46, 218-228.
-
(2009)
J. Vasc. Res.
, vol.46
, pp. 218-228
-
-
Daruwalla, J.1
Greish, K.2
Wilson, C.M.3
Muralidharan, V.4
Iyer, A.5
Maeda, H.6
Christophi, C.7
-
85
-
-
0019478990
-
A new approach to cancer chemotherapy: selective enhancement of tumor blood flow with angiotensin II
-
Suzuki, M., Hori, K., Abe, I., Saito, S. and Sato, H. (1981) A new approach to cancer chemotherapy: selective enhancement of tumor blood flow with angiotensin II. J. Natl. Cancer Inst. 67, 663-669.
-
(1981)
J. Natl. Cancer Inst.
, vol.67
, pp. 663-669
-
-
Suzuki, M.1
Hori, K.2
Abe, I.3
Saito, S.4
Sato, H.5
-
86
-
-
0026079974
-
Fluctuations in tumor blood flow under normotension and the effect of angiotensin II-induced hypertension
-
Hori, K., Suzuki, M., Tanda, S., Saito, S., Shinozaki, M. and Zhang, Q.H. (1991) Fluctuations in tumor blood flow under normotension and the effect of angiotensin II-induced hypertension. Jpn. J. Cancer Res. 82, 1309-1316.
-
(1991)
Jpn. J. Cancer Res.
, vol.82
, pp. 1309-1316
-
-
Hori, K.1
Suzuki, M.2
Tanda, S.3
Saito, S.4
Shinozaki, M.5
Zhang, Q.H.6
-
87
-
-
0027299899
-
Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure
-
Li, C.J., Miyamoto, Y., Kojima, Y. and Maeda, H. (1993) Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure. Br. J. Cacner 67, 975-980.
-
(1993)
Br. J. Cacner
, vol.67
, pp. 975-980
-
-
Li, C.J.1
Miyamoto, Y.2
Kojima, Y.3
Maeda, H.4
-
88
-
-
70449374917
-
Elevating blood pressure as a strategy to increase tumor targeted delivery of macromolecular drug SMANCS: cases of advanced solid tumors
-
Nagamitsu, A., Greish, K. and Maeda, H. (2009) Elevating blood pressure as a strategy to increase tumor targeted delivery of macromolecular drug SMANCS: cases of advanced solid tumors. Jpn. J. Clin. Oncol. 39, 756-766.
-
(2009)
Jpn. J. Clin. Oncol.
, vol.39
, pp. 756-766
-
-
Nagamitsu, A.1
Greish, K.2
Maeda, H.3
-
89
-
-
70649088695
-
Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglycerin application
-
Seki, T., Fang, J. and Maeda, H. (2009) Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglycerin application. Cancer Sci. 100, 2426-2430.
-
(2009)
Cancer Sci
, vol.100
, pp. 2426-2430
-
-
Seki, T.1
Fang, J.2
Maeda, H.3
-
90
-
-
77349118467
-
Nitroglycerin enhances vascular blood flow and drug delivery in hypoxic tumor tissues: analogy between angina pectoris and solid tumors and enhancement of the EPR effect
-
Maeda, H. (2010) Nitroglycerin enhances vascular blood flow and drug delivery in hypoxic tumor tissues: analogy between angina pectoris and solid tumors and enhancement of the EPR effect. J. Control. Release 142, 296-298.
-
(2010)
J. Control. Release
, vol.142
, pp. 296-298
-
-
Maeda, H.1
-
91
-
-
0023277458
-
Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase
-
Feelisch, M. and Noack, E. (1987) Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase. Eur. J. Pharmacol. 139, 19-30.
-
(1987)
Eur. J. Pharmacol.
, vol.139
, pp. 19-30
-
-
Feelisch, M.1
Noack, E.2
-
92
-
-
0002555527
-
The chemical properties of nitric oxide and related nitrogen oxides
-
(ed. Ignarro, L.J.). Academic Press, San Diego
-
Fukuto, J.M., Cho, J.Y. and Switzer, C.H. (2000) The chemical properties of nitric oxide and related nitrogen oxides. In Nitric Oxide: Biology and Pathobiology (ed. Ignarro, L.J.). Academic Press, San Diego, pp. 23-39.
-
(2000)
Nitric Oxide: Biology and Pathobiology
, pp. 23-39
-
-
Fukuto, J.M.1
Cho, J.Y.2
Switzer, C.H.3
-
93
-
-
0027145634
-
Hypoxic mammalian cell radiosensitization by nitric oxide
-
Mitchell, J.B., Wink, D.A., DeGraff, W., Gamson, J., Keefer, L.K. and Krishna, M.C. (1993) Hypoxic mammalian cell radiosensitization by nitric oxide. Cancer Res. 53, 5845-5848.
-
(1993)
Cancer Res
, vol.53
, pp. 5845-5848
-
-
Mitchell, J.B.1
Wink, D.A.2
DeGraff, W.3
Gamson, J.4
Keefer, L.K.5
Krishna, M.C.6
-
94
-
-
33644838950
-
Randomized phase II trial comparing nitroglycerin plus vinorelbine and cisplatin with vinorelbine and cisplatin alone in previously untreated stage IIIB/IV non-small cell lung cancer
-
Yasuda, H., Yamaya, M., Nakayama, K., Sasaki, T., Ebihara, S., Kanda, A., Asada, M., Inoue, D., Suzuki, T., Okazaki, T., Takahashi, H., Yoshida, M., Kaneta, T., Ishizawa, K., Yamanda, S., Tomita, N., Yamasaki, M., Kikuchi, A., Kubo, H. and Sasaki, H. (2006) Randomized phase II trial comparing nitroglycerin plus vinorelbine and cisplatin with vinorelbine and cisplatin alone in previously untreated stage IIIB/IV non-small cell lung cancer. J. Clin. Oncol. 24, 688-694.
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 688-694
-
-
Yasuda, H.1
Yamaya, M.2
Nakayama, K.3
Sasaki, T.4
Ebihara, S.5
Kanda, A.6
Asada, M.7
Inoue, D.8
Suzuki, T.9
Okazaki, T.10
Takahashi, H.11
Yoshida, M.12
Kaneta, T.13
Ishizawa, K.14
Yamanda, S.15
Tomita, N.16
Yamasaki, M.17
Kikuchi, A.18
Kubo, H.19
Sasaki, H.20
more..
-
95
-
-
33845303951
-
Nitroglycerin treatment may increase response to docetaxel and carboplatin regimen via inhibitions of hypoxia-inducible factor-1 pathway and P-glycoprotein in patients with lung adenocarcinoma
-
Yasuda, H., Nakayama, K., Watanabe, M., Suzuki, S., Fuji, H., Okinaga, S., Kanda, A., Zayazu, K., Sasaki, T., Asada, M., Suzuki, T., Yoshida, M., Yamanda, S., Inoue, D., Kaneta, T., Kondo, T., Takai, Y., Sasaki, H., Yanagihara, K. and Yamaya, M. (2006) Nitroglycerin treatment may increase response to docetaxel and carboplatin regimen via inhibitions of hypoxia-inducible factor-1 pathway and P-glycoprotein in patients with lung adenocarcinoma. Clin. Cancer Res. 12, 6748-6757.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 6748-6757
-
-
Yasuda, H.1
Nakayama, K.2
Watanabe, M.3
Suzuki, S.4
Fuji, H.5
Okinaga, S.6
Kanda, A.7
Zayazu, K.8
Sasaki, T.9
Asada, M.10
Suzuki, T.11
Yoshida, M.12
Yamanda, S.13
Inoue, D.14
Kaneta, T.15
Kondo, T.16
Takai, Y.17
Sasaki, H.18
Yanagihara, K.19
Yamaya, M.20
more..
-
96
-
-
84860741403
-
Therapeutic applications of nitric oxide for malignant tumor in animal models and human studies
-
(ed. Bonavida, B.). Springer Science, New York
-
Yasuda, H., Yanagihara, K., Nakayama, K., Mio, T., Sasaki, T., Asada, M., Yamaya, M. and Fukushima, M. (2010) Therapeutic applications of nitric oxide for malignant tumor in animal models and human studies. In Nitric Oxide and Cancer (ed. Bonavida, B.). Springer Science, New York, pp. 419-441.
-
(2010)
Nitric Oxide and Cancer
, pp. 419-441
-
-
Yasuda, H.1
Yanagihara, K.2
Nakayama, K.3
Mio, T.4
Sasaki, T.5
Asada, M.6
Yamaya, M.7
Fukushima, M.8
-
97
-
-
70349466391
-
Phase II study of nitric oxide donor for men with increasing prostate-specific antigen level after surgery or radiotherapy for prostate cancer
-
Siemens, D.R., Heaton, J.P.W., Adams, M.A., Kawakami, J. and Graham, C.H. (2009) Phase II study of nitric oxide donor for men with increasing prostate-specific antigen level after surgery or radiotherapy for prostate cancer. Urology 74, 878-883.
-
(2009)
Urology
, vol.74
, pp. 878-883
-
-
Siemens, D.R.1
Heaton, J.P.W.2
Adams, M.A.3
Kawakami, J.4
Graham, C.H.5
-
98
-
-
0034267721
-
Changes in tumor oxygenation/perfusion induced by the no donor, isosorbide dinitrate, in comparison with carbogen: monitoring by EPR and MRI
-
Jordan, B.F., Misson, P.D., Remeure, R., Baudelet, C., Beghein, N. and Gallez, B. (2000) Changes in tumor oxygenation/perfusion induced by the no donor, isosorbide dinitrate, in comparison with carbogen: monitoring by EPR and MRI. Int. J. Radiat. Oncol. Biol. Phys. 48, 565-570.
-
(2000)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.48
, pp. 565-570
-
-
Jordan, B.F.1
Misson, P.D.2
Remeure, R.3
Baudelet, C.4
Beghein, N.5
Gallez, B.6
-
99
-
-
0026520905
-
Enhanced tumor localization of monoclonal antibody by treatment with kininase II inhibitor and angiotensin II
-
Noguchi, A., Takahashi, T., Yamaguchi, T., Kitamura, K., Noguchi, A., Tsurumi, H., Takashina, K. and Maeda, H. (1992) Enhanced tumor localization of monoclonal antibody by treatment with kininase II inhibitor and angiotensin II. Jpn. J. Cancer Res. 83, 240-243.
-
(1992)
Jpn. J. Cancer Res.
, vol.83
, pp. 240-243
-
-
Noguchi, A.1
Takahashi, T.2
Yamaguchi, T.3
Kitamura, K.4
Noguchi, A.5
Tsurumi, H.6
Takashina, K.7
Maeda, H.8
-
100
-
-
0034009815
-
Tumor-selective blood flow decrease induced by an angiotensin converting enzyme inhibitor, temocapril hydrochloride
-
Hori, K., Saito, S., Takahashi, H., Sato, H., Maeda, H. and Sato, Y. (2000) Tumor-selective blood flow decrease induced by an angiotensin converting enzyme inhibitor, temocapril hydrochloride. Jpn. J. Cancer Res. 91, 261-269.
-
(2000)
Jpn. J. Cancer Res.
, vol.91
, pp. 261-269
-
-
Hori, K.1
Saito, S.2
Takahashi, H.3
Sato, H.4
Maeda, H.5
Sato, Y.6
|