Generation of drug-resistant mutants of Helicobacter pylori in the presence of peroxynitrite, a derivative of nitric oxide, at pathophysiological concentration

Microbiology and Immunology

Volumn 53, Issue 1, 2009, Pages 1-7

  Kuwahara, Hideo ^a   Kariu, Tohru ^b   Fang, Jun ^b   Maeda, Hiroshi ^b  

^a KUMAMOTO HEALTH SCIENCE UNIVERSITY   (Japan)

^b SOJO UNIVERSITY   (Japan)

Author keywords

23S rRNA; Drug resistant mutant; Free radical; Peroxynitrite

Indexed keywords

CLARITHROMYCIN; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; RNA 23S; ANTIINFECTIVE AGENT; BACTERIAL DNA; BACTERIAL PROTEIN; DRUG DERIVATIVE; NITRIC OXIDE; PEROXYNITROUS ACID;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM MUTANT; CHEMICAL MODIFICATION; CONTROLLED STUDY; DNA SEQUENCE; HELICOBACTER PYLORI; IMMUNE RESPONSE; INFLAMMATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RNA SEQUENCE; DRUG EFFECT; ENZYMOLOGY; GENETICS; HELICOBACTER INFECTION; HUMAN; METABOLISM; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MUTATION;

BACTERIA (MICROORGANISMS); HELICOBACTER PYLORI;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXYNITROUS ACID; RNA, RIBOSOMAL, 23S;

EID: 61749098693     PISSN: 03855600     EISSN: 13480421     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2008.00089.x     Document Type: Article

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