S-allylmercaptocysteine reduces carbon tetrachloride-induced hepatic oxidative stress and necroinflammation via nuclear factor kappa B-dependent pathways in mice

European Journal of Nutrition

Volumn 51, Issue 3, 2012, Pages 323-333

  Xiao, Jia ^a   Liong, Emily C ^a   Ling, Ming Tat ^b   Ching, Yick Pang ^a   Fung, Man Lung ^a   Tipoe, George L ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

Carbon tetrachloride; Liver injury; Necroinflammation; Nuclear factor B; Oxidative stress; S allylmercaptocysteine

Indexed keywords

ALANINE AMINOTRANSFERASE; CARBON TETRACHLORIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MALONALDEHYDE; NITRIC OXIDE; PLANT MEDICINAL PRODUCT; PROTEIN P50; S ALLYLMERCAPTOCYSTEINE; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; FEMALE; GARLIC; GENE EXPRESSION REGULATION; HEPATITIS; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER NECROSIS; LIVER REGENERATION; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; CARBON TETRACHLORIDE; CYSTEINE; DRUG-INDUCED LIVER INJURY; FEMALE; INFLAMMATION; LIPID PEROXIDATION; LIVER; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED C57BL; NF-KAPPA B; NITRIC OXIDE; OXIDATIVE STRESS;

ALLIUM SATIVUM; MUS;

EID: 84860671363     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-011-0217-0     Document Type: Article

References (42)

1. Muriel P (1998) Nitric oxide protection of rat liver from lipid peroxidation, collagen accumulation, and liver damage induced by carbon tetrachloride. Biochem Pharmacol 56:773-779 (Pubitemid 28454589)
2. Weber LW, Boll M, Stampfl A (2003) Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model. Crit Rev Toxicol 33:105-136. doi:10.1080/713611034 (Pubitemid 36432872)
3. Fleischauer AT, Arab L (2001) Garlic and cancer: a critical review of the epidemiologic literature. J Nutr 131:1032S-1040S (Pubitemid 32197292)
4. Xiao D, Pinto JT, Soh JW, Deguchi A, Gundersen GG, Palazzo AF, Yoon JT, Shirin H, Weinstein IB (2003) Induction of apoptosis by the garlic-derived compound S-allylmercaptocys-teine (SAMC) is associated with microtubule depolymerization and c-Jun. NH (2)-terminal kinase 1 activation. Cancer Res 63:6825-6837 (Pubitemid 37322965)
5. Ban JO, Yuk DY, Woo KS, Kim TM, Lee US, Jeong HS, Kim DJ, Chung YB, Hwang BY, Oh KW, Hong JT (2007) Inhibition of cell growth and induction of apoptosis via inactivation of NF-kappaB by a sulfur compound isolated from garlic in human colon cancer cells. J Pharmacol Sci 104:374-383
6. Lee Y (2008) Induction of apoptosis by S-allylmercapto-L-cys-teine, a biotransformed garlic derivative, on a human gastric cancer cell line. Int J Mol Med 21:765-770
7. Howard EW, Ling MT, Chua CW, Cheung HW, Wang X, Wong YC (2007) Garlic-derived S-allylmercaptocysteine is a novel in vivo antimetastatic agent for androgen-independent prostate cancer. Clin Cancer Res 13:1847-1856. doi:10.1158/1078-0432. CCR-06-2074 (Pubitemid 46952955)
8. Pedraza-Chaverri J, Barrera D, Maldonado PD, Chirino YI, Macias-Ruvalcaba NA, Medina-Campos ON, Castro L, Salcedo MI, Hernandez-Pando R (2004) S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates genta-micin-induced oxidative and nitrosative stress and renal damage in vivo. BMC Clin Pharmacol 4:5. doi:10.1186/1472-6904-4-5 (Pubitemid 38751349)
9. Sumioka I, Matsura T, Yamada K (2001) Therapeutic effect of S-allylmercaptocysteine on acetaminophen-induced liver injury in mice. Eur J Pharmacol 433:177-185 (Pubitemid 34045178)
10. Nakagawat S, Kasuga S, Matsuura H (1989) Prevention of liver damage by aged garlic extract and its components in mice. Phytother Res 3:50-53. doi:10.1002/ptr.2650030203 (Pubitemid 19195462)
11. Sumioka I, Matsura T, Kasuga S, Itakura Y, Yamada K (1998) Mechanisms of protection by S-allylmercaptocysteine against acetaminophen-induced liver injury in mice. Jpn J Pharmacol 78:199-207 (Pubitemid 28508409)
12. Tipoe GL, Leung TM, Hung MW, Fung ML (2007) Green tea polyphenols as an anti-oxidant and anti-inflammatory agent for cardiovascular protection. Cardiovasc Hematol Disord Drug Target 7:135-144 (Pubitemid 47024129)
13. Leung TM, Tipoe GL, Liong EC, Lau TY, Fung ML, Nanji AA (2008) Endothelial nitric oxide synthase is a critical factor in experimental liver fibrosis. Int J Exp Pathol 89:241-250. doi:10.1111/j.1365-2613.2008.00590.x (Pubitemid 352019180)
14. Taieb D, Malicet C, Garcia S, Rocchi P, Arnaud C, Dagorn JC, Iovanna JL, Vasseur S (2005) Inactivation of stress protein p8 increases murine carbon tetrachloride hepatotoxicity via preserved CYP2E1 activity. Hepatology 42:176-182. doi:10.1002/hep. 20759 (Pubitemid 40911325)
15. Marra F (2002) Chemokines in liver inflammation and fibrosis. Front Biosci 7: d1899-d1914
16. Slater TF, Cheeseman KH, Ingold KU (1985) Carbon tetrachlo-ride toxicity as a model for studying free-radical mediated liver injury. Philos Trans R Soc Lond B Biol Sci 311:633-645
17. Shaker ME, Houssen ME, Abo-Hashem EM, Ibrahim TM (2009) Comparison of vitamin E, L-carnitine and melatonin in ameliorating carbon tetrachloride and diabetes induced hepatic oxidative stress. J Physiol Biochem 65:225-233. doi:10.1007/BF03180575
18. Tipoe GL, Leung TM, Liong EC, Lau TY, Fung ML, Nanji AA (2010) Epigallocatechin-3-gallate (EGCG) reduces liver inflammation, oxidative stress and fibrosis in carbon tetrachloride (CCl4)-induced liver injury in mice. Toxicology 273:45-52. doi:10.1016/j.tox.2010.04.014
19. Shim JY, Kim MH, Kim HD, Ahn JY, Yun YS, Song JY (2010) Protective action of the immunomodulator ginsan against carbon tetrachloride-induced liver injury via control of oxidative stress and the inflammatory response. Toxicol Appl Pharmacol 242:318-325. doi:10.1016/j.taap. 2009.11.005
20. Shi H, Dong L, Zhang Y, Bai Y, Zhao J, Zhang L (2010) Protective effect of a coffee preparation (Nescafe pure) against carbon tetrachloride-induced liver fibrosis in rats. Clin Nutr 29:399-405. doi:10.1016/j.clnu.2009.12.007
21. Popovic M, Vukmirovic S, Stilinovic N, Capo I, Jakovljevic V (2010) Anti-oxidative activity of an aqueous suspension of commercial preparation of the mushroom Coprinus comatus. Molecules 15:4564-4571. doi:10.3390/ molecules15074564
22. Larrey D (2000) Drug-induced liver diseases. J Hepatol 32:77-88 (Pubitemid 30123626)
23. Lieber CS (2000) Alcoholic liver disease: new insights in path-ogenesis lead to new treatments. J Hepatol 32:113-128 (Pubitemid 30123629)
24. Ozer J, Ratner M, Shaw M, Bailey W, Schomaker S (2008) The current state of serum biomarkers of hepatotoxicity. Toxicology 245:194-205. doi:10.1016/j.tox.2007.11.021
25. Rhee SG, Chang TS, Bae YS, Lee SR, Kang SW (2003) Cellular regulation by hydrogen peroxide. J Am Soc Nephrol 14:S211-S215 (Pubitemid 36903927)
26. Edwards MJ, Keller BJ, Kauffman FC, Thurman RG (1993) The involvement of Kupffer cells in carbon tetrachloride toxicity. Toxicol Appl Pharmacol 119:275-279. doi:10.1006/taap. 1993. 1069 (Pubitemid 23122838)
27. Streetz KL, Wustefeld T, Klein C, Manns MP, Trautwein C (2001) Mediators of inflammation and acute phase response in the liver. Cell Mol Biol (Noisy-le-grand) 47:661-673
28. Smart DE, Vincent KJ, Arthur MJ, Eickelberg O, Castellazzi M, Mann J, Mann DA (2001) JunD regulates transcription of the tissue inhibitor of metalloproteinases-1 and interleukin-6 genes in activated hepatic stellate cells. J Biol Chem 276:24414-24421. doi:10.1074/jbc. M101840200
29. Roberts RA, James NH, Cosulich S, Hasmall SC, Orphanides G (2001) Role of cytokines in non-genotoxic hepatocarcinogenesis: cause or effect? Toxicol Lett 120:301-306 (Pubitemid 32375096)
30. Zhu RZ, Xiang D, Xie C, Li JJ, Hu JJ, He HL, Yuan YS, Gao J, Han W, Yu Y (2010) Protective effect of recombinant human IL-1Ra on CCl4-induced acute liver injury in mice. World J Gastroenterol 16:2771-2779
31. Hoek JB, Pastorino JG (2002) Ethanol, oxidative stress, and cytokine-induced liver cell injury. Alcohol 27:63-68 (Pubitemid 34626486)
32. Wahl SM, McCartney-Francis N, Chan J, Dionne R, Ta L, Orenstein JM (2003) Nitric oxide in experimental joint inflammation. Benefit or detriment? Cells Tissues Organs 174:26-33. doi:10.1159/000070572 (Pubitemid 36677091)
33. Tsuchiyama T, Nakamoto Y, Sakai Y, Mukaida N, Kaneko S (2008) Optimal amount of monocyte chemoattractant protein-1 enhances antitumor effects of suicide gene therapy against hepatocellular carcinoma by M1 macrophage activation. Cancer Sci 99:2075-2082. doi:10.1111/j.1349-7006.2008.00951.x
34. Bautista AP (1997) Chronic alcohol intoxication induces hepatic injury through enhanced macrophage inflammatory protein-2 production and intercellular adhesion molecule-1 expression in the liver. Hepatology 25:335-342. doi:10.1002/hep. 510250214 (Pubitemid 27069052)
35. Chen X (2010) Protective effects of quercetin on liver injury induced by ethanol. Pharmacogn Mag 6:135-141. doi:10.4103/0973-1296.62900
36. Gewiese-Rabsch J, Drucker C, Malchow S, Scheller J, Rose-John S (2010) Role of IL-6 trans-signaling in CCl (4) induced liver damage. Biochim Biophys Acta 1802:1054-1061. doi:10.1016/j.bbadis.2010.07.023
37. Zuinen R, Yamaji K, Aoki M, Chikuma T, Hojo H (2007) Early induced, high-level interleukin-6 expression in the rat peritoneal cavity into which a hepatotoxicant carbon tetrachloride was administered. Toxicol Lett 170:42-48. doi:10.1016/j.toxlet.2007. 02.003 (Pubitemid 46498904)
38. Tsuchiya S, Tsukamoto Y, Taira E, La Marre J (2007) Involvement of transforming growth factor-beta in the expression of gicerin, a cell adhesion molecule, in the regeneration of hepato-cytes. Int J Mol Med 19:381-386
39. Bonizzi G, Karin M (2004) The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol 25:280-288. doi:10.1016/j.it.2004.03.008 (Pubitemid 38610351)
40. Gloire G, Legrand-Poels S, Piette J (2006) NF-kappaB activation by reactive oxygen species: fifteen years later. Biochem Pharmacol 72:1493-1505. doi:10.1016/j.bcp. 2006.04.011 (Pubitemid 44666727)
41. Liaudet L, Soriano FG, Szabo C (2000) Biology of nitric oxide signaling. Crit Care Med 28: N37-N52 (Pubitemid 30262046)
42. Takada Y, Mukhopadhyay A, Kundu GC, Mahabeleshwar GH, Singh S, Aggarwal BB (2003) Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase. J Biol Chem 278:24233-24241. doi:10.1074/jbc. M212389200 (Pubitemid 36830260)