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Volumn 302, Issue 9, 2012, Pages

Transcription factor CHF1/Hey2 regulates EC coupling and heart failure in mice through regulation of FKBP12.6

Author keywords

Cardiac failure; Gene regulation; Hypertrophy; Transcription factors

Indexed keywords

BINDING PROTEIN; RYANODINE RECEPTOR; TACROLIMUS; TRANSCRIPTION FACTOR;

EID: 84860540848     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00702.2011     Document Type: Article
Times cited : (10)

References (44)
  • 1
    • 0030878260 scopus 로고    scopus 로고
    • Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo
    • Agah R, Frenkel PA, French BA, Michael LH, Overbeek PA, Schneider MD. Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo. J Clin Invest 100: 169-179, 1997.
    • (1997) J Clin Invest , vol.100 , pp. 169-179
    • Agah, R.1    Frenkel, P.A.2    French, B.A.3    Michael, L.H.4    Overbeek, P.A.5    Schneider, M.D.6
  • 2
    • 0038578664 scopus 로고    scopus 로고
    • Calcium and heart failure: The cycle game
    • Chien KR, Ross J Jr, Hoshijima M. Calcium and heart failure: the cycle game. Nat Med 9: 508-509, 2003.
    • (2003) Nat Med , vol.9 , pp. 508-509
    • Chien, K.R.1    Ross Jr., J.2    Hoshijima, M.3
  • 3
    • 0034011764 scopus 로고    scopus 로고
    • Cardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular system
    • Chin MT, Maemura K, Fukumoto S, Jain MK, Layne MD, Watanabe M, Hsieh CM, Lee ME. Cardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular system. J Biol Chem 275: 6381-6387, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 6381-6387
    • Chin, M.T.1    Maemura, K.2    Fukumoto, S.3    Jain, M.K.4    Layne, M.D.5    Watanabe, M.6    Hsieh, C.M.7    Lee, M.E.8
  • 4
    • 0037125957 scopus 로고    scopus 로고
    • Tetralogy of Fallot and other congenital heart defects in Hey2 mutant mice
    • Donovan J, Kordylewska A, Jan YN, Utset MF. Tetralogy of Fallot and other congenital heart defects in Hey2 mutant mice. Curr Biol 12: 1605-1610, 2002.
    • (2002) Curr Biol , vol.12 , pp. 1605-1610
    • Donovan, J.1    Kordylewska, A.2    Jan, Y.N.3    Utset, M.F.4
  • 8
    • 77953812124 scopus 로고    scopus 로고
    • Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks
    • Guo T, Cornea RL, Huke S, Camors E, Yang Y, Picht E, Fruen BR, Bers DM. Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks. Circ Res 106: 1743-1752, 2010.
    • (2010) Circ Res , vol.106 , pp. 1743-1752
    • Guo, T.1    Cornea, R.L.2    Huke, S.3    Camors, E.4    Yang, Y.5    Picht, E.6    Fruen, B.R.7    Bers, D.M.8
  • 9
    • 33748323383 scopus 로고    scopus 로고
    • Regulation of cardiac hypertrophy by intracellular signalling pathways
    • Heineke J, Molkentin JD. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 7: 589-600, 2006.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 589-600
    • Heineke, J.1    Molkentin, J.D.2
  • 12
    • 34147188988 scopus 로고    scopus 로고
    • CHF1/Hey2 plays a pivotal role in left ventricular maturation through suppression of ectopic atrial gene expression
    • Koibuchi N, Chin MT. CHF1/Hey2 plays a pivotal role in left ventricular maturation through suppression of ectopic atrial gene expression. Circ Res 100: 850-855, 2007.
    • (2007) Circ Res , vol.100 , pp. 850-855
    • Koibuchi, N.1    Chin, M.T.2
  • 14
    • 48549085587 scopus 로고    scopus 로고
    • 2+ binding properties and regulatory unit interactions alter kinetics of tension development and relaxation in rabbit skeletal muscle
    • 2+ binding properties and regulatory unit interactions alter kinetics of tension development and relaxation in rabbit skeletal muscle. J Physiol 586: 3683-3700, 2008.
    • (2008) J Physiol , vol.586 , pp. 3683-3700
    • Kreutziger, K.L.1    Piroddi, N.2    Scellini, B.3    Tesi, C.4    Poggesi, C.5    Regnier, M.6
  • 15
    • 0033166951 scopus 로고    scopus 로고
    • Hey genes: A novel subfamily of hairy- and enhancer of split related genes specifically expressed during mouse embryogenesis
    • Leimeister C, Externbrink A, Klamt B, Gessler M. Hey genes: a novel subfamily of hairy- and enhancer of split related genes specifically expressed during mouse embryogenesis. Mech Dev 85: 173-177, 1999.
    • (1999) Mech Dev , vol.85 , pp. 173-177
    • Leimeister, C.1    Externbrink, A.2    Klamt, B.3    Gessler, M.4
  • 16
    • 0030002580 scopus 로고    scopus 로고
    • The progression from hypertension to congestive heart failure
    • Levy D, Larson MG, Vasan RS, Kannel WB, Ho KK. The progression from hypertension to congestive heart failure. JAMA 275: 1557-1562, 1996.
    • (1996) JAMA , vol.275 , pp. 1557-1562
    • Levy, D.1    Larson, M.G.2    Vasan, R.S.3    Kannel, W.B.4    Ho, K.K.5
  • 17
    • 0037109094 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of GLUT1 prevents the development of heart failure attributable to pressure overload in mice
    • Liao R, Jain M, Cui L, D'Agostino J, Aiello F, Luptak I, Ngoy S, Mortensen RM, Tian R. Cardiac-specific overexpression of GLUT1 prevents the development of heart failure attributable to pressure overload in mice. Circulation 106: 2125-2131, 2002.
    • (2002) Circulation , vol.106 , pp. 2125-2131
    • Liao, R.1    Jain, M.2    Cui, L.3    D'Agostino, J.4    Aiello, F.5    Luptak, I.6    Ngoy, S.7    Mortensen, R.M.8    Tian, R.9
  • 19
    • 77952632689 scopus 로고    scopus 로고
    • The bHLH transcription factor CHF1/Hey2 regulates susceptibility to apoptosis and heart failure after pressure overload
    • Liu Y, Yu M, Wu L, Chin MT. The bHLH transcription factor CHF1/Hey2 regulates susceptibility to apoptosis and heart failure after pressure overload. Am J Physiol Heart Circ Physiol 298: H2082-H2092, 2010.
    • (2010) Am J Physiol Heart Circ Physiol , vol.298
    • Liu, Y.1    Yu, M.2    Wu, L.3    Chin, M.T.4
  • 20
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2[-delta delta C(T)] method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2[-delta delta C(T)] method. Methods 25: 402-408, 2001.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 25
    • 0032715827 scopus 로고    scopus 로고
    • HRT1, HRT2, and HRT3: A new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments
    • Nakagawa O, Nakagawa M, Richardson JA, Olson EN, Srivastava D. HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments. Dev Biol 216: 72-84, 1999.
    • (1999) Dev Biol , vol.216 , pp. 72-84
    • Nakagawa, O.1    Nakagawa, M.2    Richardson, J.A.3    Olson, E.N.4    Srivastava, D.5
  • 26
    • 0035793341 scopus 로고    scopus 로고
    • Overexpression of FK506-binding protein FKBP12.6 in cardiomyocytes reduces ryanodine receptor-mediated Ca(2+) leak from the sarcoplasmic reticulum and increases contractility
    • Prestle J, Janssen PM, Janssen AP, Zeitz O, Lehnart SE, Bruce L, Smith GL, Hasenfuss G. Overexpression of FK506-binding protein FKBP12.6 in cardiomyocytes reduces ryanodine receptor-mediated Ca(2+) leak from the sarcoplasmic reticulum and increases contractility. Circ Res 88: 188-194, 2001.
    • (2001) Circ Res , vol.88 , pp. 188-194
    • Prestle, J.1    Janssen, P.M.2    Janssen, A.P.3    Zeitz, O.4    Lehnart, S.E.5    Bruce, L.6    Smith, G.L.7    Hasenfuss, G.8
  • 28
    • 0037058935 scopus 로고    scopus 로고
    • Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2
    • Sakata Y, Kamei CN, Nakagami H, Bronson R, Liao JK, Chin MT. Ventricular septal defect and cardiomyopathy in mice lacking the transcription factor CHF1/Hey2. Proc Natl Acad Sci U S A 99: 16197-16202, 2002.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 16197-16202
    • Sakata, Y.1    Kamei, C.N.2    Nakagami, H.3    Bronson, R.4    Liao, J.K.5    Chin, M.T.6
  • 29
    • 31444450744 scopus 로고    scopus 로고
    • The spectrum of cardiovascular anomalies in CHF1/Hey2 deficient mice reveals roles in endocardial cushion, myocardial and vascular maturation
    • Sakata Y, Koibuchi N, Xiang F, Youngblood JM, Kamei CN, Chin MT. The spectrum of cardiovascular anomalies in CHF1/Hey2 deficient mice reveals roles in endocardial cushion, myocardial and vascular maturation. J Mol Cell Cardiol 40: 267-273, 2006.
    • (2006) J Mol Cell Cardiol , vol.40 , pp. 267-273
    • Sakata, Y.1    Koibuchi, N.2    Xiang, F.3    Youngblood, J.M.4    Kamei, C.N.5    Chin, M.T.6
  • 30
    • 8344241891 scopus 로고    scopus 로고
    • Transcription factor CHF1/Hey2 regulates neointimal formation in vivo and vascular smooth muscle proliferation and migration in vitro
    • Sakata Y, Xiang F, Chen Z, Kiriyama Y, Kamei CN, Simon DI, Chin MT. Transcription factor CHF1/Hey2 regulates neointimal formation in vivo and vascular smooth muscle proliferation and migration in vitro. Arterioscler Thromb Vasc Biol 24: 2069-2074, 2004.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 2069-2074
    • Sakata, Y.1    Xiang, F.2    Chen, Z.3    Kiriyama, Y.4    Kamei, C.N.5    Simon, D.I.6    Chin, M.T.7
  • 34
    • 1542319162 scopus 로고    scopus 로고
    • Mouse cardiac surgery: Comprehensive techniques for the generation of mouse models of human diseases and their application for genomic studies
    • Tarnavski O, McMullen JR, Schinke M, Nie Q, Kong S, Izumo S. Mouse cardiac surgery: comprehensive techniques for the generation of mouse models of human diseases and their application for genomic studies. Physiol Genomics 16: 349-360, 2004.
    • (2004) Physiol Genomics , vol.16 , pp. 349-360
    • Tarnavski, O.1    McMullen, J.R.2    Schinke, M.3    Nie, Q.4    Kong, S.5    Izumo, S.6
  • 36
    • 77957889301 scopus 로고    scopus 로고
    • Transcription factor CHF1/Hey2 regulates coronary vascular maturation
    • Watanabe T, Koibuchi N, Chin MT. Transcription factor CHF1/Hey2 regulates coronary vascular maturation. Mech Dev 127: 418-427, 2010.
    • (2010) Mech Dev , vol.127 , pp. 418-427
    • Watanabe, T.1    Koibuchi, N.2    Chin, M.T.3
  • 37
    • 4444382387 scopus 로고    scopus 로고
    • Calcium-calcineurin signaling in the regulation of cardiac hypertrophy
    • Wilkins BJ, Molkentin JD. Calcium-calcineurin signaling in the regulation of cardiac hypertrophy. Biochem Biophys Res Commun 322: 1178-1191, 2004.
    • (2004) Biochem Biophys Res Commun , vol.322 , pp. 1178-1191
    • Wilkins, B.J.1    Molkentin, J.D.2
  • 40
    • 34249932672 scopus 로고    scopus 로고
    • Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function
    • Xin M, Small EM, van Rooij E, Qi X, Richardson JA, Srivastava D, Nakagawa O, Olson EN. Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function. Proc Natl Acad Sci U S A 104: 7975-7980, 2007.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 7975-7980
    • Xin, M.1    Small, E.M.2    van Rooij, E.3    Qi, X.4    Richardson, J.A.5    Srivastava, D.6    Nakagawa, O.7    Olson, E.N.8
  • 41
    • 33846395496 scopus 로고    scopus 로고
    • In vitro and in vivo effects of bone marrow stem cells on cardiac structure and function
    • Xu M, Uemura R, Dai Y, Wang Y, Pasha Z, Ashraf M. In vitro and in vivo effects of bone marrow stem cells on cardiac structure and function. J Mol Cell Cardiol 42: 441-448, 2007.
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 441-448
    • Xu, M.1    Uemura, R.2    Dai, Y.3    Wang, Y.4    Pasha, Z.5    Ashraf, M.6
  • 42
    • 73149104185 scopus 로고    scopus 로고
    • CHF1/Hey2 promotes physiological hypertrophy in response to pressure overload through selective repression and activation of specific transcriptional pathways
    • Yu M, Liu Y, Xiang F, Li Y, Cullen D, Liao R, Beyer RP, Bammler TK, Chin MT. CHF1/Hey2 promotes physiological hypertrophy in response to pressure overload through selective repression and activation of specific transcriptional pathways. OMICS 13: 501-511, 2009.
    • (2009) OMICS , vol.13 , pp. 501-511
    • Yu, M.1    Liu, Y.2    Xiang, F.3    Li, Y.4    Cullen, D.5    Liao, R.6    Beyer, R.P.7    Bammler, T.K.8    Chin, M.T.9
  • 43
    • 77953652449 scopus 로고    scopus 로고
    • Transcription factor CHF1/Hey2 regulates specific pathways in serum stimulated primary cardiac myocytes: Implications for cardiac hypertrophy
    • Yu M, Xiang F, Beyer RP, Farin FM, Bammler TK, Chin MT. Transcription factor CHF1/Hey2 regulates specific pathways in serum stimulated primary cardiac myocytes: implications for cardiac hypertrophy. Curr Genomics 11: 287-296, 2010.
    • (2010) Curr Genomics , vol.11 , pp. 287-296
    • Yu, M.1    Xiang, F.2    Beyer, R.P.3    Farin, F.M.4    Bammler, T.K.5    Chin, M.T.6
  • 44
    • 65549134641 scopus 로고    scopus 로고
    • Local control of excitationcontraction coupling in human embryonic stem cell-derived cardiomyocytes
    • Zhu WZ, Santana LF, Laflamme MA. Local control of excitationcontraction coupling in human embryonic stem cell-derived cardiomyocytes. PLos One 4: e5407, 2009.
    • (2009) PLos One , vol.4
    • Zhu, W.Z.1    Santana, L.F.2    Laflamme, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.