Cell therapy enhances function of remote non-infarcted myocardium

Journal of Molecular and Cellular Cardiology

Volumn 47, Issue 5, 2009, Pages 603-613

  Moreno Gonzalez, Alicia ^a   Korte, F Steven ^a   Dai, Jin ^a   Chen, Kent ^b   Ho, Bryan ^a   Reinecke, Hans ^b   Murry, Charles E ^a,b   Regnier, Michael ^a,b  

^a University of Washington   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cardiomyocytes; Cell Therapy; Myocardial infarction; Myofibrillar proteins; Phosphorylation

Indexed keywords

CALCIUM; ISOPROTEIN; MUSCLE PROTEIN; MYOSIN; MYOSIN LIGHT CHAIN 2; TROPOMYOSIN; TROPONIN T;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY OCCLUSION; ARTICLE; CELL THERAPY; CELL TRANSPLANTATION; CONTROLLED STUDY; HEART CONTRACTION; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE COMPLIANCE; HEART VENTRICLE FUNCTION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MUSCLE FIBER CONTRACTION; MUSCLE FIBRIL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SCAR;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CARDIAC MYOSINS; CELLS, CULTURED; ECHOCARDIOGRAPHY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MICROSCOPY, ELECTRON, TRANSMISSION; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; MYOSIN LIGHT CHAINS; PHOSPHORYLATION; RATS; TISSUE THERAPY; TROPOMYOSIN;

RATTUS;

EID: 70349739456     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.07.030     Document Type: Article

References (51)

1. Reffelmann T., and Kloner R.A. Cellular cardiomyoplasty-cardiomyocytes, skeletal myoblasts, or stem cells for regenerating myocardium and treatment of heart failure?. Cardiovasc. Res. 58 2 (2003 May 1) 358-368
2. Murry C.E., Field L.J., and Menasche P. Cell-based cardiac repair: reflections at the 10-year point. Circulation 112 20 (2005 Nov. 15) 3174-3183
3. Laflamme M.A., and Murry C.E. Regenerating the heart. Nat. Biotechnol. 23 7 (2005 Jul.) 845-856
4. Li R.K., Jia Z.Q., Weisel R.D., Mickle D.A., Zhang J., Mohabeer M.K., et al. Cardiomyocyte transplantation improves heart function. Ann. Thorac. Surg. 62 3 (1996 Sep.) 654-660 discussion 60-1
5. Sakai T., Li R.K., Weisel R.D., Mickle D.A., Jia Z.Q., Tomita S., et al. Fetal cell transplantation: a comparison of three cell types. J. Thorac. Cardiovasc. Surg. 118 4 (1999 Oct) 715-724
6. Muller-Ehmsen J., Peterson K.L., Kedes L., Whittaker P., Dow J.S., Long T.I., et al. Rebuilding a damaged heart: long-term survival of transplanted neonatal rat cardiomyocytes after myocardial infarction and effect on cardiac function. Circulation 105 (2002) 1720-1726
7. Laflamme M.A., Zbinden S., Epstein S.E., and MC E. Cell-based therapy for myocardial ischemia and infarction: pathophysiological mechanisms. Annu. Rev. Pathol. Mech. Dis. 2 (2007) 307-339
8. Reinecke H., and Murry C.E. Cell grafting for cardiac repair. Methods in Molecular Biology 219 (2003) 97-112
9. Ismail J.A., Poppa V., Kemper L.E., Scatena M., Giachelli C.M., Coffin J.D., et al. Immunohistologic labeling of murine endothelium. Cardiovasc. Pathol. 12 2 (2003 Mar.-Apr.) 82-90
10. Etzion S., Battler A., Barbash I.M., Cagnano E., Zarin P., Granot Y., et al. Influence of embryonic cardiomyocyte transplantation on the progression of heart failure in a rat model of extensive myocardial infarction. J. Mol. Cell Cardiol. 33 7 (2001 Jul.) 1321-1330
11. Laflamme M.A., Chen K.Y., Naumova A.V., Muskheli V., Fugate J.A., Dupras S.K., et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat. Biotechnol. 25 9 (2007 Sep.) 1015-1024
12. Chase P.B., and Kushmerick M.J. Effects of pH on contraction of rabbit fast and slow skeletal muscle fibers. Biophys. J 53 6 (1988 Jun.) 935-946
13. Regnier M., Rivera A.J., Wang C.K., Bates M.A., Chase P.B., and Gordon A.M. Thin filament near-neighbour regulatory unit interactions affect rabbit skeletal muscle steady-state force-Ca(2+) relations. J. Physiol. 540 Pt 2 (2002 Apr. 15) 485-497
14. Messer A.E., Jacques A.M., and Marston S.B. Troponin phosphorylation and regulatory function in human heart muscle: dephosphorylation of Ser23/24 on troponin I could account for the contractile defect in end-stage heart failure. J. Mol. Cell Cardiol. 42 1 (2007 Jan.) 247-259
15. Muller-Ehmsen J., Whittaker P., Kloner R.A., Dow J.S., Sakoda T., Long T.I., et al. Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardium. J. Mol. Cell Cardiol. 34 2 (2002 Feb.) 107-116
16. Scorsin M., Hagege A.A., Marotte F., Mirochnik N., Copin H., Barnoux M., et al. Does transplantation of cardiomyocytes improve function of infarcted myocardium?. Circulation 96 9 Suppl. (1997 Nov. 4) II-188-II-193
17. Huwer H., Winning J., Vollmar B., Welter C., Lohbach C., Menger M.D., et al. Long-term cell survival and hemodynamic improvements after neonatal cardiomyocyte and satellite cell transplantation into healed myocardial cryoinfarcted lesions in rats. Cell Transplant. 12 7 (2003) 757-767
18. Prakash Y.S., Cody M.J., Housmans P.R., Hannon J.D., and Sieck G.C. Comparison of cross-bridge cycling kinetics in neonatal vs. adult rat ventricular muscle. J. Muscle Res. Cell Motil. 20 7 (1999 Oct.) 717-723
19. Reiser P.J., Westfall M.V., Schiaffino S., and Solaro R.J. Tension production and thin-filament protein isoforms in developing rat myocardium. Am. J. Physiol. 267 4 Pt 2 (1994 Oct.) H1589-H1596
20. Korte F.S., Herron T.J., Rovetto M.J., and McDonald K.S. Power output is linearly related to MyHC content in rat skinned myocytes and isolated working hearts. Am. J. Physiol. Heart Circ. Physiol 289 2 (2005 August 1, 2005) H801-H812
21. Fitzsimons D.P., Patel J.R., and Moss R.L. Role of myosin heavy chain composition in kinetics of force development and relaxation in rat myocardium. J. Physiol. Lond. 513 (1998) 171-183
22. Cappelli V., Bottinelli R., Poggesi C., Moggio R., and Reggiani C. Shortening velocity and myosin and myofibrillar ATPase activity related to myosin isoenzyme composition during postnatal development in rat myocardium. Circ. Res 65 2 (1989 Aug.) 446-457
23. Schillinger W., and Kogler H. Altered phosphorylation and Ca2+-sensitivity of myofilaments in human heart failure. Cardiovasc. Res 57 1 (2003 Jan.) 5-7
24. van der Velden J., Papp Z., Zaremba R., Boontje N.M., de Jong J.W., Owen V.J., et al. Increased Ca2+-sensitivity of the contractile apparatus in end-stage human heart failure results from altered phosphorylation of contractile proteins. Cardiovasc. Res. 57 1 (2003 Jan.) 37-47
25. Bilchick K.C., Duncan J.G., Ravi R., Takimoto E., Champion H.C., Gao W.D., et al. Heart failure-associated alterations in troponin I phosphorylation impair ventricular relaxation-afterload and force-frequency responses and systolic function. Am. J. Physiol. Heart Circ. Physiol. 292 1 (2007 Jan.) H125-H318
26. Noland Jr. T.A., and Kuo J.F. Phosphorylation of cardiac myosin light chain 2 by protein kinase C and myosin light chain kinase increases Ca(2+)-stimulated actomyosin MgATPase activity. Biochem. Biophys. Res. Commun. 193 1 (1993 May 28) 254-260
27. Lahmers S., Wu Y., Call D.R., Labeit S., and Granzier H. Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium. Circ. Res. 94 4 (2004 Mar. 5) 505-513
28. Whittaker P. Collagen organization in wound healing after myocardial injury. Basic Res. Cardiol. 93 Suppl. 3 (1998) 23-25
29. Sicard R.E., and Werner J.C. Dexamethasone-induced histopathology of neonatal rat myocardium. In Vivo 8 3 (1994 May-Jun.) 353-358
30. Cleutjens J.P., and Creemers E.E. Integration of concepts: cardiac extracellular matrix remodeling after myocardial infarction. J. Card. Fail 8 6 Suppl. (2002 Dec.) S344-S348
31. E. Page, H.A. Fozzard, R.J. Solaro, Handbook of Physiology, Section 2: The Cardiovascular System, Vol I: The Heart. 1st edition ed: An American Physiological Society Book; 2001.
32. Wang J., Liu X., Sentex E., Takeda N., and Dhalla N.S. Increased expression of protein kinase C isoforms in heart failure due to myocardial infarction. Am. J. Physiol. Heart Circ. Physiol. 284 6 (2003 Jun.) H2277-H2287
33. Bowling N., Walsh R.A., Song G., Estridge T., Sandusky G.E., Fouts R.L., et al. Increased protein kinase C activity and expression of Ca2+-sensitive isoforms in the failing human heart. Circulation 99 3 (1999 Jan. 26) 384-391
34. Murphy S., and Frishman W.H. Protein kinase C in cardiac disease and as a potential therapeutic target. Cardiology in review 13 1 (2005 Jan.-Feb.) 3-12
35. Van der Velden J., Merkus D., Klarenbeek B.R., James A.T., Boontje N.M., Dekkers D.H.W., et al. Alterations in myofilament function contribute to left ventricular dysfunction in pigs early after myocardial infarction. Circ. Res. 95 (2004) e85-e95
36. Belin R.J., Sumandea M.P., Kobayashi T., Walker L.A., Rundell V.L., Urboniene D., et al. Left ventricular myofilament dysfunction in rat experimental hypertrophy and congestive heart failure. Am. J. Physiol. Heart Circ. Physiol. 291 5 (2006) H2344-H2353
37. de Waard M.C., van der Velden J., Bito V., Ozdemir S., Biesmans L., Boontje N.M., et al. Early exercise training normalized myofilament function and attenuates left ventricular pump dysfunction in mice with a large myocardial infarction. Circ. Res. 100 7 (2007) 1079-1088
38. Mou Y.A., Reboul C., Andre L., Lacampagne A., and Cazorla O. Late exercise training improves non-uniformity of transmural myocardial function in rats with ischaemic heart failure. Cardiovascular Research 81 3 (2009) 555-564
39. Li P., Hofmann P.A., Li B., Malhotra A., Cheng W., Sonnenblick E.H., et al. Myocardial infarction alters myofilament calcium sensitivity and mechanical behavior of myocytes. American Journal of Physiology 272 1 (1997) H360-H370
40. Wagner K.D., Theres H., Born A., Strube S., Wunderlich N., Pfitzer G., et al. Contractile function of papillary muscle from rats with different infarct size after beta-adrenergic blockade and ACE-inhibition. J. Mol. Cell Cardiol. 29 11 (1997 Nov.) 2941-2951
41. Geenen D.L., White T.P., and Lampman R.M. Papillary mechanics and cardiac morphology of infarcted rat hearts after training. J. Appl. Physiol. 63 1 (1987) 92-96
42. Gupta M.P., Samant S.A., Smith S.H., and Shroff S.G. HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity. J. Biol. Chem. 283 15 (2008) 10135-10146
43. Martin A.F., Ball K., Gao L.Z., Kumar P., and Solaro R.J. Identification and functional significance of troponin I isoforms in neonatal rat heart myofibrils. Circ. Res. 69 5 (1991 Nov) 1244-1252
44. Granzier H.L., and Irving T.C. Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filaments. Biophys. J. 68 (1995) 1027-1044
45. Berry M.F., Engler A.J., Woo Y.J., Pirolli T.J., Bish L.T., Jayasankar V., et al. Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance. American Journal of Physiology 290 (2006) H2196-H2203
46. Whittaker P., Muller-Ehmsen J., Dow J.S., Kedes L.H., and Kloner R.A. Development of abnormal tissue architecture in transplanted neonatal rat myocytes. Ann. Thorac. Surg. 75 5 (2003 May) 1450-1456
47. Wall S.T., Walker J.C., Healy K.E., Ratcliffe M.B., and Guccione J.M. Theoretical impact of the injection of material into the myocardium: a finite element model simulation. Circulation 114 24 (2006 Dec. 12) 2627-2635
48. Hutcheson K.A., Atkins B.Z., Hueman M.T., Hopkins M.B., Glower D.D., and Taylor D.A. Comparison of benefits on myocardial performance of cellular cardiomyoplasty with skeletal myoblasts and fibroblasts. Cell Transplant 9 3 (2000 May-Jun.) 359-368
49. Fujii T., Yau T.M., Weisel R.D., Ohno N., Mickle D.A., Shiono N., et al. Cell transplantation to prevent heart failure: a comparison of cell types. Ann. Thorac Surg. 76 6 (2003 Dec.) 2062-2070 discussion 70
50. Berry M.F., Engler A.J., Woo Y.J., Pirolli T.J., Bish L.T., Jayasankar V., et al. Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance. Am. J. Physiol. Heart Circ. Physiol. 290 6 (2006 Jun) H2196-H2203
51. Sakai T., Li R.K., Weisel R.D., Mickle D.A., Kim E.J., Tomita S., et al. Autologous heart cell transplantation improves cardiac function after myocardial injury. Ann. Thorac Surg. 68 6 (1999 Dec.) 2074-2080 discussion 80-1