Tightening of the ATP-binding sites induces the opening of P2X receptor channels

EMBO Journal

Volumn 31, Issue 9, 2012, Pages 2134-2143

  Jiang, Ruotian ^a   Taly, Antoine ^a   Lemoine, Damien ^a   Martz, Adeline ^a   Cunrath, Olivier ^a   Grutter, Thomas ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

allosteric mechanism; ligand gated ion channels; normal mode analysis; purinergic receptors zinc binding sites

Indexed keywords

ADENOSINE TRIPHOSPHATE; ION CHANNEL; PURINERGIC P2X2 RECEPTOR; ZINC;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN STRUCTURE;

ADENOSINE TRIPHOSPHATE; BINDING SITES; HEK293 CELLS; HUMANS; PROTEIN BINDING; PURINERGIC P2X RECEPTOR AGONISTS; PURINERGIC P2X RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2X2; ZINC;

EID: 84860540831     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.75     Document Type: Article

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