Strychnine activates neuronal α7 nicotinic receptors after mutations in the leucine ring and transmitter binding site domains

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 23, 1999, Pages 13421-13426

  Palma, Eleonora ^a   Fucile, Sergio ^a   Barabino, Benedetta ^a   Miledi, Ricardo ^b,c   Eusebi, Fabrizio ^a,d  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CENTRO DE FÍSICA APLICADA Y TECNOLOGÍA AVANZADA   (Mexico)

^d Dipartimento di Medicina Sperimentale e Patologia   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BUNGAROTOXIN; COMPLEMENTARY DNA; CYSTEINE; GLYCINE RECEPTOR; LEUCINE; NEUROTRANSMITTER; NICOTINIC AGENT; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; STRYCHNINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DRUG BINDING SITE; MEMBRANE CONDUCTANCE; MEMBRANE CURRENT; MUTATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR AFFINITY; XENOPUS LAEVIS;

ANIMALS; BASE SEQUENCE; BINDING SITES; CHICKENS; DNA PRIMERS; ION CHANNEL GATING; LEUCINE; MUTAGENESIS, SITE-DIRECTED; NEURONS; NEUROTRANSMITTER AGENTS; NICOTINIC AGONISTS; RECEPTORS, NICOTINIC; STRYCHNINE; XENOPUS;

ANIMALIA; STRYCHNOS TOXIFERA; XENOPUS LAEVIS;

EID: 0033539686     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.23.13421     Document Type: Article

References (29)

1. Garcia-Colunga, J. & Miledi, R. (1994) Proc. Natl. Acad. Sci. USA 96, 4113-4118.
2. Matsuhayashi, H., Alkondon, M., Pereira, E. F., Swanson, K. L. & Albuquerque, E. X. (1998) J. Pharmacol. Exp. Ther. 284, 904-913.
3. Anand, R., Peng, X. & Lindstrom J. (1993) FEBS Lett. 327, 241-246.
4. Anand, R., Peng, X., Ballesta J. & Lindstrom J. (1993) Mol. Pharmacol. 44, 1046-1050.
5. Gerzanich, V., Anand, R. & Lindstrom, J. (1994) Mol. Pharmacol. 45, 212-220.
6. Peng, X., Katz, M., Gerzanich, V., Anand, R. & Lindstrom, J. (1994) Mol. Pharmacol. 45, 546-554.
7. Rothlin, C. V., Katz, E., Verbitsky, M. & Elgoyhen, A. B. (1999) Mol. Pharmacol 55, 248-254.
8. Zhang, Z., Vijayaraghavan, S. & Berg, D. K. (1994) Neuron 12, 167-177.
9. Revah, F., Bertrand, D., Galzi, J. L., Devillers-Thiery, A., Mulle, C., Hussy, N., Bertrand S., Ballivet, M. & Changeux J. P. (1991) Nature (London) 353, 846-849.
10. Bertrand, D., Devillers-Thiery, A., Revah, F., Galzi, J. L., Hussy, N., Mulle, C., Bertrand, S., Ballivet, M. & Changeux, J. P. (1992) Proc. Natl. Acad. Sci. USA 89, 1261-1265.
11. Palma, E., Mileo, A. M., Eusehi, F. & Miledi, R. (1996) Proc. Natl. Acad. Sci. USA 93, 11231-11235.
12. Maggi, L., Palma, E., Miledi, R. & Eusebi, F. (1998) Mol. Psychiatry 3, 350-355.
13. Karlin, A. (1993) Curr Biol. 3, 299-309.
14. Galzi, J.-L. & Changeux, J.-P. (1994) Curr. Biol. 4, 554-565.
15. Lindstrom, J. (1996) in Ion Channels, ed. Narahashi, T. (Plenum, Chicago), pp. 377-450.
16. Palma, E., Bertrand, S., Binzoni, T. & Bertrand, D. (1996) J. Physiol. (London) 491, 151-161.
17. Bertrand, S., Devillers-Thiery, A., Palma, E., Buisson, B., Edelstein, S. J., Corringer, P. J., Changeux, J. P. & Bertrand, D. (1997) NeuroReport 8, 3591-3596.
18. Miledi, R., Parker, I. & Sumikawa, K. (1983) Proc. R. Soc. London Ser. B 218, 481-484.
19. Palma, E., Maggi, L., Miledi R. & Eusebi, F. (1998) Proc. Natl. Acad. Sci. USA 95, 10246-10250.
20. Palma, E., Maggi, L., Eusebi, F. & Miledi, R. (1997) Proc. Natl. Acad. Sci. USA 94, 9915-9919.
21. Palma, E., Maggi, L., Barabino, B., Eusebi, F. & Ballivet, M. (1999) J. Biol. Chem. 274, 18335-18340.
22. Colquhoun, D. & Ogden, D. C. (1988) J. Physiol. (London) 395, 131-159.
23. Role, L. W. & Berg., D. K. (1996) Neuron 16, 1077-1085.
24. Karlin, A. & Akabas, M. H. (1995) Neuron 15, 1231-1244.
25. Galzi, J.-L., Bertrand, D., Devillers-Thiery A., Revah, F., Bertrand, S. & Changeux, J. P. (1991) FEBS Lett. 294, 198-202.
26. Bertazzon, A., Conti-Tronconi, B. M. & Raftery, M. A. (1992) Proc. Natl. Acad. Sci. USA 89, 9632-9636.
27. Lal, R. & Yu, L. (1993) Proc. Natl. Acad. Sci. USA 90, 7280-7284.
28. Anand, R., Conroy, W. G., Schoepfer, R., Whiting, P. & Lindstrom, J. (1991) J. Biol. Chem. 17, 11192-11198.
29. Cooper, E., Couturier S. & Ballivet, M. (1991) Nature (London) 350, 235-238.