Human cataract mutations in EPHA2 SAM domain alter receptor stability and function

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Park, Jeong Eun ^a   Son, Alexander I ^a   Hua, Rui ^b   Wang, Lianqing ^b   Zhang, Xue ^b   Zhou, Renping ^a  

^a RUTGERS UNIVERSITY   (United States)

^b INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

EPHRIN A5; EPHRIN RECEPTOR A2; LIGAND; MUTANT PROTEIN; PROTEASOME; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CATARACT; CELL MIGRATION; CHROMOSOME 1P; CONTROLLED STUDY; ENZYME ACTIVATION; EPHA2 GENE; EPITHELIUM CELL; GENE; GENE FUNCTION; GENE MUTATION; GENETIC DISORDER; HUMAN; HUMAN CELL; LENS EPITHELIUM; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; WILD TYPE;

ANIMALS; CATARACT; CELL LINE; CELL MOVEMENT; ENZYME ACTIVATION; EPHRIN-A5; GENE ORDER; HUMANS; MICE; MICE, KNOCKOUT; MUTATION; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STABILITY; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPHA2; SIGNAL TRANSDUCTION; TYROSINE; UBIQUITIN;

EID: 84860531878     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036564     Document Type: Article

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