Regulation of a disintegrin and metalloprotease-33 expression by transforming growth factor-β

American Journal of Respiratory Cell and Molecular Biology

Volumn 46, Issue 5, 2012, Pages 633-640

  Yang, Youwen ^a   Wicks, James ^a   Haitchi, Hans Michael ^a   Powell, Robert M ^a   Manuyakorn, Wiparat ^a   Howarth, Peter H ^a   Holgate, Stephen T ^a   Davies, Donna E ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

A disintegrin and metalloprotease 33; Histone modification; Myofibroblast; Transforming growth factor

Indexed keywords

A DISINTEGRIN AND METALLOPROTEASE 33 PROTEIN; ADAM PROTEIN; HISTONE H3; LYSINE; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG;

ADULT; ARTICLE; ASTHMA; BRONCHUS; BRONCHUS BIOPSY; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CELL GROWTH; CHROMATIN CONDENSATION; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEACETYLATION; DNA METHYLATION; DOWN REGULATION; EPITHELIUM CELL; FEMALE; FIBROBLAST; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC VARIABILITY; HISTONE MODIFICATION; HUMAN; HUMAN CELL; MALE; MYOFIBROBLAST; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN METABOLISM; PROTEIN METHYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; WESTERN BLOTTING;

ACETYLATION; ADAM PROTEINS; ADULT; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; FEMALE; HUMANS; MALE; METHYLATION; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; RNA SPLICING; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 84860511178     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2011-0030OC     Document Type: Article

References (55)

1. Juniper EF, Kline PA, Vanzieleghem MA, Ramsdale EH, O'Byrne PM, Hargreave FE. Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness and clinical asthma in nonsteroid-dependent asthmatics. Am Rev Respir Dis 1990; 142:832-836. (Pubitemid 20344653)
2. Van Eerdewegh P, Little RD, Dupuis J, Del Mastro RG, Falls K, Simon J, Torrey D, Pandit S, McKenny J, Brausnschweiger K, et al. Association of the ADAM-33 gene with asthma and bronchial hyperresponsiveness. Nature 2002;418:426-430. (Pubitemid 34826843)
3. Holgate ST, Yang Y, Haitchi HM, Powell RM, Holloway JW, Yoshisue H, Pang YY, Cakebread J, Davies DE. The genetics of asthma: ADAM33 as an example of a susceptibility gene. Proc Am Thorac Soc 2006;3:440-443. (Pubitemid 44033360)
4. Blakey J, Halapi E, Bjornsdottir US, Wheatley A, Kristinsson S, Upmanyu R, Stefansson K, Hakonarson H, Hall IP. The contribution of ADAM 33 polymorphisms to the population risk of asthma. Thorax 2005;60:274-276. (Pubitemid 40522361)
5. Li X, Zhang Y, Zhang J, Xiao Y, Huang J, Tian C, He C, Deng Y, Yang Y, Fan H. Asthma susceptible genes in Chinese population: a meta-analysis. Respir Res 2010;11:129.
6. Michel S, Liang L, Depner M, Klopp N, Ruether A, Kumar A, Schedel M, Vogelberg C, von Mutius E, von Berg A, et al. Unifying candidate gene and GWAS approaches in asthma. PLoS One 2010;5:e13894.
7. Simpson A, Maniatis N, Jury F, Cakebread JA, Lowe LA, Holgate ST, Woodcock A, Ollier WE, Collins A, Custovic A, et al. Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function. Am J Respir Crit Care Med 2005;172:55-60. (Pubitemid 40923314)
8. Jongepier H, Boezen HM, Dijkstra A, Howard TD, Vonk JM, Koppelman GH, Zheng SL, Meyers DA, Bleecker ER, Postma DS. Polymorphisms of the ADAM33 gene are associated with accelerated lung function decline in asthma. Clin Exp Allergy 2004;34:757-760. (Pubitemid 38736791)
9. van Diemen CC, Postma DS, Vonk JM, Bruinenberg M, Schouten JP, Boezen HMA, Disintegrin A. Metalloprotease 33 polymorphisms and lung function decline in the general population. Am J Respir Crit Care Med 2005;172:329-333. (Pubitemid 41026143)
10. Gosman MM, Boezen HM, van Diemen CC, Snoeck-Stroband JB, Lapperre TS, Hiemstra PS, Ten Hacken NH, Stolk J, Postma DS. A disintegrin and metalloproteinase 33 and chronic obstructive pulmonary disease pathophysiology. Thorax 2007;62:242-247. (Pubitemid 46579805)
11. Xiao J, Han J, Wang X, Hua D, Su D, Bao Y, Lv F. Association of ADAM33 gene with susceptibility to COPD in Tibetan population of China. Mol Biol Rep 2011;38:4941-4945.
12. van Goor H, Melenhorst WB, Turner AJ, Holgate ST. Adamalysins in biology and disease. J Pathol 2009;219:277-286.
13. Haitchi HM, Powell RM, Shaw TJ, Howarth PH, Wilson SJ, Wilson DI, Holgate ST, Davies DE. ADAM33 expression in asthmatic airways and human embryonic lungs. Am J Respir Crit Care Med 2005;171:958-965. (Pubitemid 40616943)
14. Yang Y, Haitchi HM, Cakebread J, Sammut D, Harvey A, Powell RM, Holloway JW, Howarth P, Holgate ST, Davies DE. Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells. J Allergy Clin Immunol 2008;121:1393-1399.
15. Powell RM, Wicks J, Holloway JW, Holgate ST, Davies DE. The splicing and fate of ADAM33 transcripts in primary human airways fibroblasts. Am J Respir Cell Mol Biol 2004;31:13-21. (Pubitemid 38888034)
16. Ito I, Laporte JD, Fiset PO, Asai K, Yamauchi Y, Martin JG, Hamid Q. Downregulation of a disintegrin and metalloproteinase 33 by IFN-gamma in human airway smooth muscle cells. J Allergy Clin Immunol 2007;119:89-97. (Pubitemid 46037804)
17. Dijkstra A, Postma DS, Noordhoek JA, LodewijkME, Kauffman HF, Ten Hacken NH, Timens W. Expression of ADAMs ("a disintegrin and metalloprotease" ) in the human lung. Virchows Arch 2009;454:441-449.
18. Foley SC, Mogas AK, Olivenstein R, Fiset PO, Chakir J, Bourbeau J, Ernst P, Lemiere C, Martin JG, Hamid Q. Increased expression of ADAM33 and ADAM8 with disease progression in asthma. J Allergy Clin Immunol 2007;119:863-871. (Pubitemid 46527832)
19. Erbek SS, Erinanc H, Erbek S, Topal O, Kiyici H. Expression of a disintegrin and metalloproteinase 33 protein in nasal polyposis: an immunohistochemical study. Am J Rhinol Allergy 2010;24:79-82.
20. Lee JY, Park SW, Chang HK, Kim HY, Rhim T, Lee JH, Jang AS, Koh ES, Park CS. A disintegrin and metalloproteinase 33 protein in patients with asthma: relevance to airflow limitation. Am J Respir Crit Care Med 2006;173:729-735.
21. Puxeddu I, Pang YY, Harvey A, Haitchi HM, Nicholas B, Yoshisue H, Ribatti D, Clough G, Powell RM, Murphy G, et al. The soluble form of a disintegrin and metalloprotease 33 promotes angiogenesis: implications for airway remodeling in asthma. J Allergy Clin Immunol 2008;121:1400-1406.
22. Redington AE, Madden J, Frew AJ, Djukanovic R, Roche WR, Holgate ST, Howarth PH. Transforming growth factor-β1 in asthma: measurement in bronchoalveolar lavage fluid. Am J Respir Crit Care Med 1997;156:642-647. (Pubitemid 27352007)
23. Wicks J, Haitchi HM, Holgate ST, Davies DE, Powell RM. Enhanced upregulation of smooth muscle related transcripts by TGF beta2 in asthmatic (myo) fibroblasts. Thorax 2006;61:313-319.
24. Hurd SZ. Workshop summary and guidelines: investigative use of bronchoscopy, lavage, and bronchial biopsies in asthma and other airway diseases. J Allergy Clin Immunol 1991;88:808-814.
25. Holgate ST, Davies DE, Lackie PM, Wilson SJ, Puddicombe SM, Lordan JL. Epithelial-mesenchymal interactions in the pathogenesis of asthma. J Allergy Clin Immunol 2000;105:193-204. (Pubitemid 30109029)
26. Puddicombe SM, Polosa R, Richter A, Krishna MT, Howarth PH, Holgate ST, Davies DE. Involvement of the epidermal growth factor receptor in epithelial repair in asthma. FASEB J 2000;14:1362-1374. (Pubitemid 30439745)
27. Green MR, Yoon H, Boss JM. Epigenetic regulation during B cell differentiation controls CIITA promoter accessibility. J Immunol 2006; 177:3865-3873. (Pubitemid 44359921)
28. Honda H, Pazin MJ, Ji H,Wernyj RP, Morin PJ. Crucial roles of Sp1 and epigenetic modifications in the regulation of the CLDN4 promoter in ovarian cancer cells. J Biol Chem 2006;281:21433-21444. (Pubitemid 44115482)
29. Barth TK, Imhof A. Fast signals and slow marks: the dynamics of histone modifications. Trends Biochem Sci 2010;35:618-626.
30. Lau JC, Hanel ML, Wevrick R. Tissue-specific and imprinted epigenetic modifications of the human NDN gene. Nucleic Acids Res 2004;32: 3376-3382. (Pubitemid 39117453)
31. Rao S, Procko E, Shannon MF. Chromatin remodeling, measured by a novel real-time polymerase chain reaction assay, across the proximal promoter region of the IL-2 gene. J Immunol 2001;167:4494-4503. (Pubitemid 32954327)
32. Lan RY, Selmi C, Gershwin ME. The regulatory, inflammatory, and T cell programming roles of interleukin-2 (IL-2). J Autoimmun 2008; 31:7-12.
33. Grainger DJ, Mosedale DE, Metcalfe JC, Weissberg PL, Kemp PR. Active and acid-activatable TGF-beta in human sera, platelets and plasma. Clin Chim Acta 1995;235:11-31.
34. Balzar S, Chu HW, Silkoff P, Cundall M, Trudeau JB, Strand M, Wenzel S. Increased TGF-beta2 in severe asthma with eosinophilia. J Allergy Clin Immunol 2005;115:110-117. (Pubitemid 40075429)
35. Howat WJ, Holgate ST, Lackie PM. TGF-beta isoform release and activation during in vitro bronchial epithelial wound repair. Am J Physiol Lung Cell Mol Physiol 2002;282:L115-L123. (Pubitemid 34654188)
36. Roghani M, Becherer JD, Moss ML, Atherton RE, Erdjument-Bromage H, Arribas J, Blackburn RK, Weskamp G, Tempst P, Blobel CP. Metalloprotease- disintegrin MDC9: intracellular maturation and catalytic activity. J Biol Chem 1999;274:3531-3540. (Pubitemid 29077194)
37. Lum L, Reid MS, Blobel CP. Intracellular maturation of the mouse metalloprotease disintegrin MDC15. J Biol Chem 1998;273:26236-26247. (Pubitemid 28475862)
38. Soond SM, Everson B, Riches DW, Murphy G. ERK-mediated phosphorylation of Thr735 in TNFalpha-converting enzyme and its potential role in TACE protein trafficking. J Cell Sci 2005;118:2371-2380. (Pubitemid 40873077)
39. Lee DH, Goldberg AL. Proteasome inhibitors: valuable new tools for cell biologists. Trends Cell Biol 1998;8:397-403. (Pubitemid 28458705)
40. Warburton D, Bellusci S, De Langhe S, Del Moral PM, Fleury V, Mailleux A, Tefft D, Unbekandt M, Wang K, Shi W. Molecular mechanisms of early lung specification and branching morphogenesis. Pediatr Res 2005;57:26R-37R. (Pubitemid 40593243)
41. Derynck R, Zhang Y, Feng XH. Smads: transcriptional activators of TGF-beta responses. Cell 1998;95:737-740. (Pubitemid 29014453)
42. Schmierer B, Hill CS. TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol 2007;8: 970-982. (Pubitemid 350174642)
43. Garcia-Cao M, O'Sullivan R, Peters AH, Jenuwein T, Blasco MA. Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. Nat Genet 2004;36: 94-99. (Pubitemid 38056214)
44. West AG, Attikum H. Chromatin at the crossroads. Meeting on Signalling to Chromatin Epigenetics. EMBO Rep 2006;7:1206-1210. (Pubitemid 44835086)
45. Cloos PA, Christensen J, Agger K, Maiolica A, Rappsilber J, Antal T, Hansen KH, Helin K. The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3. Nature 2006;442:307-311. (Pubitemid 44114906)
46. Chen Y, Yang Y, Wang F, Wan K, Yamane K, Zhang Y, Lei M. Crystal structure of human histone lysine-specific demethylase 1 (LSD1). Proc Natl Acad Sci USA 2006;103:13956-13961. (Pubitemid 44452964)
47. Forneris F, Binda C, Dall'aglio A, Fraaije MW, Battaglioli E, Mattevi A. A highly specific mechanism of histone H3-K4 recognition by histone demethylase LSD1. J Biol Chem 2006;281:35289-35295. (Pubitemid 46036567)
48. Cha TL, Zhou BP, Xia W, Wu Y, Yang CC, Chen CT, Ping B, Otte AP, Hung MC. Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3. Science 2005;310:306-310. (Pubitemid 41457195)
49. Tan NY, Khachigian LM. Sp1 phosphorylation and its regulation of gene transcription. Mol Cell Biol 2009;29:2483-2488.
50. Doetzlhofer A, Rotheneder H, Lagger G, Koranda M, Kurtev V, Brosch G, Wintersberger E, Seiser C. Histone deacetylase 1 can repress transcription by binding to Sp1. Mol Cell Biol 1999;19:5504-5511. (Pubitemid 29339908)
51. Su RC, Brown KE, Saaber S, Fisher AG, Merkenschlager M, Smale ST. Dynamic assembly of silent chromatin during thymocyte maturation. Nat Genet 2004;36:502-506. (Pubitemid 38620036)
52. Siegfried Z, Eden S, Mendelsohn M, Feng X, Tsuberi BZ, Cedar H. DNA methylation represses transcription in vivo. Nat Genet 1999;22: 203-206. (Pubitemid 29264820)
53. Haitchi H-M, Bassett D, Bucchieri F, Gao X, Powell R, Hanley NA, Wilson DI, Holgate ST, Davies DE. Induction of a disintegrin and metalloprotease 33 during embryonic lung development and the influence of IL-13 or maternal allergy. J Allergy Clin Immunol 2009;124: 590-597.
54. Richter A, Puddicombe SM, Lordan JL, Bucchieri F, Wilson SJ, Djukanovic R, Dent G, Holgate ST, Davies DE. The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma. Am J Respir Cell Mol Biol 2001;25:385-391. (Pubitemid 32918922)
55. Haitchi HM, Yang Y, Wicks J, Murphy G, Powell RM, Howarth P, Holgate ST, Davies DE. TGF-β down regulates ADAM33 expression during myofibroblast differentiation via histone modification [abstract]. Eur Respir J 2009;28:E3096.