Use of transcriptional regulatory elements of the MUC-1 and ERBB2 genes to drive tumour-selective expression of a prodrug activating enzyme

Gene Therapy

Volumn 4, Issue 10, 1997, Pages 1045-1052

  Ring, C J A ^a   Blouin, P ^a   Martin, L A ^a   Hurst, H C ^a   Lemoine, N R ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

ERBB2; HER2 neu; MUC1 promoter; Retroviral vectors; Suicide gene; Tumor selective expression

Indexed keywords

DRUG METABOLIZING ENZYME; GANCICLOVIR; MUCIN; PRODRUG; RECOMBINANT DNA; THYMIDINE KINASE;

ANTIBIOTIC SENSITIVITY; ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; DRUG TARGETING; GENE THERAPY; GENETIC TRANSDUCTION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; ONCOGENE NEU; PRIORITY JOURNAL; PROMOTER REGION; RETROVIRUS; TRANSCRIPTION REGULATION; TUMOR; VIRUS RECOMBINANT;

HERPES; SIMPLEXVIRUS; TUMOR VIRUS; UNIDENTIFIED RETROVIRUS;

EID: 0030730794     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300510     Document Type: Article

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