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Volumn 7, Issue 4, 2012, Pages

Transcriptome sequencing revealed significant alteration of cortical promoter usage and splicing in schizophrenia

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLECORTIN LIKE KINASE 1; NEUROLEPTIC AGENT; PHOSPHOTRANSFERASE; TRANSCRIPTOME; UNCLASSIFIED DRUG; DCLK1 PROTEIN, HUMAN; MESSENGER RNA; PROTEIN SERINE THREONINE KINASE; RNA ISOFORM; SIGNAL PEPTIDE;

EID: 84860430130     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036351     Document Type: Article
Times cited : (85)

References (82)
  • 2
    • 0036308284 scopus 로고    scopus 로고
    • Schizophrenia as a disorder of neurodevelopment
    • Lewis DA, Levitt P, (2002) Schizophrenia as a disorder of neurodevelopment. Annu Rev Neurosci 25: 409-432.
    • (2002) Annu Rev Neurosci , vol.25 , pp. 409-432
    • Lewis, D.A.1    Levitt, P.2
  • 3
    • 0034207818 scopus 로고    scopus 로고
    • The neurodevelopmental hypothesis of schizophrenia: following a trail of evidence from cradle to grave
    • Marenco S, Weinberger DR, (2000) The neurodevelopmental hypothesis of schizophrenia: following a trail of evidence from cradle to grave. Dev Psychopathol 12: 501-527.
    • (2000) Dev Psychopathol , vol.12 , pp. 501-527
    • Marenco, S.1    Weinberger, D.R.2
  • 4
    • 0035836642 scopus 로고    scopus 로고
    • Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia
    • Hakak Y, Walker JR, Li C, Wong WH, Davis KL, et al. (2001) Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proc Natl Acad Sci U S A 98: 4746-4751.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4746-4751
    • Hakak, Y.1    Walker, J.R.2    Li, C.3    Wong, W.H.4    Davis, K.L.5
  • 5
    • 12744278205 scopus 로고    scopus 로고
    • Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis
    • Iwamoto K, Bundo M, Kato T, (2005) Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis. Hum Mol Genet 14: 241-253.
    • (2005) Hum Mol Genet , vol.14 , pp. 241-253
    • Iwamoto, K.1    Bundo, M.2    Kato, T.3
  • 6
    • 0036550998 scopus 로고    scopus 로고
    • Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia
    • Middleton FA, Mirnics K, Pierri JN, Lewis DA, Levitt P, (2002) Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia. J Neurosci 22: 2718-2729.
    • (2002) J Neurosci , vol.22 , pp. 2718-2729
    • Middleton, F.A.1    Mirnics, K.2    Pierri, J.N.3    Lewis, D.A.4    Levitt, P.5
  • 7
    • 0033637841 scopus 로고    scopus 로고
    • Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex
    • Mirnics K, Middleton FA, Marquez A, Lewis DA, Levitt P, (2000) Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex. Neuron 28: 53-67.
    • (2000) Neuron , vol.28 , pp. 53-67
    • Mirnics, K.1    Middleton, F.A.2    Marquez, A.3    Lewis, D.A.4    Levitt, P.5
  • 8
    • 0035426751 scopus 로고    scopus 로고
    • Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse
    • Mirnics K, Middleton FA, Lewis DA, Levitt P, (2001) Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse. Trends Neurosci 24: 479-486.
    • (2001) Trends Neurosci , vol.24 , pp. 479-486
    • Mirnics, K.1    Middleton, F.A.2    Lewis, D.A.3    Levitt, P.4
  • 9
    • 0041328892 scopus 로고    scopus 로고
    • Oligodendrocyte dysfunction in schizophrenia and bipolar disorder
    • Tkachev D, Mimmack ML, Ryan MM, Wayland M, Freeman T, et al. (2003) Oligodendrocyte dysfunction in schizophrenia and bipolar disorder. Lancet 362: 798-805.
    • (2003) Lancet , vol.362 , pp. 798-805
    • Tkachev, D.1    Mimmack, M.L.2    Ryan, M.M.3    Wayland, M.4    Freeman, T.5
  • 10
    • 0035061298 scopus 로고    scopus 로고
    • Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia
    • Mirnics K, Middleton FA, Stanwood GD, Lewis DA, Levitt P, (2001) Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia. Mol Psychiatry 6: 293-301.
    • (2001) Mol Psychiatry , vol.6 , pp. 293-301
    • Mirnics, K.1    Middleton, F.A.2    Stanwood, G.D.3    Lewis, D.A.4    Levitt, P.5
  • 11
    • 0036843296 scopus 로고    scopus 로고
    • Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study
    • Vawter MP, Crook JM, Hyde TM, Kleinman JE, Weinberger DR, et al. (2002) Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study. Schizophr Res 58: 11-20.
    • (2002) Schizophr Res , vol.58 , pp. 11-20
    • Vawter, M.P.1    Crook, J.M.2    Hyde, T.M.3    Kleinman, J.E.4    Weinberger, D.R.5
  • 12
    • 23444444014 scopus 로고    scopus 로고
    • Variations in differential gene expression patterns across multiple brain regions in schizophrenia
    • Katsel P, Davis KL, Gorman JM, Haroutunian V, (2005) Variations in differential gene expression patterns across multiple brain regions in schizophrenia. Schizophr Res 77: 241-252.
    • (2005) Schizophr Res , vol.77 , pp. 241-252
    • Katsel, P.1    Davis, K.L.2    Gorman, J.M.3    Haroutunian, V.4
  • 13
    • 18344369874 scopus 로고    scopus 로고
    • Gene expression analysis in schizophrenia: reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22
    • Mimmack ML, Ryan M, Baba H, Navarro-Ruiz J, Iritani S, et al. (2002) Gene expression analysis in schizophrenia: reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22. Proc Natl Acad Sci U S A 99: 4680-4685.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 4680-4685
    • Mimmack, M.L.1    Ryan, M.2    Baba, H.3    Navarro-Ruiz, J.4    Iritani, S.5
  • 14
    • 0035878139 scopus 로고    scopus 로고
    • Application of cDNA microarrays to examine gene expression differences in schizophrenia
    • Vawter MP, Barrett T, Cheadle C, Sokolov BP, Wood WH 3rd, et al. (2001) Application of cDNA microarrays to examine gene expression differences in schizophrenia. Brain Res Bull 55: 641-650.
    • (2001) Brain Res Bull , vol.55 , pp. 641-650
    • Vawter, M.P.1    Barrett, T.2    Cheadle, C.3    Sokolov, B.P.4    Wood 3rd, W.H.5
  • 15
    • 32244439440 scopus 로고    scopus 로고
    • Altered gene expression in the amygdala in schizophrenia: up-regulation of genes located in the cytomatrix active zone
    • Weidenhofer J, Bowden NA, Scott RJ, Tooney PA, (2006) Altered gene expression in the amygdala in schizophrenia: up-regulation of genes located in the cytomatrix active zone. Mol Cell Neurosci 31: 243-250.
    • (2006) Mol Cell Neurosci , vol.31 , pp. 243-250
    • Weidenhofer, J.1    Bowden, N.A.2    Scott, R.J.3    Tooney, P.A.4
  • 16
    • 0041419538 scopus 로고    scopus 로고
    • Schizophrenia hippocampus has elevated expression of chondrex glycoprotein gene
    • Chung C, Tallerico T, Seeman P, (2003) Schizophrenia hippocampus has elevated expression of chondrex glycoprotein gene. Synapse 50: 29-34.
    • (2003) Synapse , vol.50 , pp. 29-34
    • Chung, C.1    Tallerico, T.2    Seeman, P.3
  • 17
    • 22444441576 scopus 로고    scopus 로고
    • Deficient hippocampal neuron expression of proteasome, ubiquitin, and mitochondrial genes in multiple schizophrenia cohorts
    • Altar CA, Jurata LW, Charles V, Lemire A, Liu P, et al. (2005) Deficient hippocampal neuron expression of proteasome, ubiquitin, and mitochondrial genes in multiple schizophrenia cohorts. Biol Psychiatry 58: 85-96.
    • (2005) Biol Psychiatry , vol.58 , pp. 85-96
    • Altar, C.A.1    Jurata, L.W.2    Charles, V.3    Lemire, A.4    Liu, P.5
  • 18
    • 33846645320 scopus 로고    scopus 로고
    • Expression of transcripts for myelination-related genes in the anterior cingulate cortex in schizophrenia
    • McCullumsmith RE, Gupta D, Beneyto M, Kreger E, Haroutunian V, et al. (2007) Expression of transcripts for myelination-related genes in the anterior cingulate cortex in schizophrenia. Schizophr Res 90: 15-27.
    • (2007) Schizophr Res , vol.90 , pp. 15-27
    • McCullumsmith, R.E.1    Gupta, D.2    Beneyto, M.3    Kreger, E.4    Haroutunian, V.5
  • 19
    • 4444324427 scopus 로고    scopus 로고
    • Microarray analysis of postmortem temporal cortex from patients with schizophrenia
    • Aston C, Jiang L, Sokolov BP, (2004) Microarray analysis of postmortem temporal cortex from patients with schizophrenia. J Neurosci Res 77: 858-866.
    • (2004) J Neurosci Res , vol.77 , pp. 858-866
    • Aston, C.1    Jiang, L.2    Sokolov, B.P.3
  • 20
    • 0033973146 scopus 로고    scopus 로고
    • Superior temporal gyrus in schizophrenia: a volumetric magnetic resonance imaging study
    • Rajarethinam RP, DeQuardo JR, Nalepa R, Tandon R, (2000) Superior temporal gyrus in schizophrenia: a volumetric magnetic resonance imaging study. Schizophr Res 41: 303-312.
    • (2000) Schizophr Res , vol.41 , pp. 303-312
    • Rajarethinam, R.P.1    DeQuardo, J.R.2    Nalepa, R.3    Tandon, R.4
  • 21
    • 28444491442 scopus 로고    scopus 로고
    • Regional deficits in brain volume in schizophrenia: a meta-analysis of voxel-based morphometry studies
    • Honea R, Crow TJ, Passingham D, Mackay CE, (2005) Regional deficits in brain volume in schizophrenia: a meta-analysis of voxel-based morphometry studies. Am J Psychiatry 162: 2233-2245.
    • (2005) Am J Psychiatry , vol.162 , pp. 2233-2245
    • Honea, R.1    Crow, T.J.2    Passingham, D.3    Mackay, C.E.4
  • 22
    • 43849100264 scopus 로고    scopus 로고
    • Altered gene expression in the superior temporal gyrus in schizophrenia
    • Bowden NA, Scott RJ, Tooney PA, (2008) Altered gene expression in the superior temporal gyrus in schizophrenia. BMC Genomics 9: 199.
    • (2008) BMC Genomics , vol.9 , pp. 199
    • Bowden, N.A.1    Scott, R.J.2    Tooney, P.A.3
  • 23
    • 15944367439 scopus 로고    scopus 로고
    • Transcriptional profiling reveals evidence for signaling and oligodendroglial abnormalities in the temporal cortex from patients with major depressive disorder
    • Aston C, Jiang L, Sokolov BP, (2005) Transcriptional profiling reveals evidence for signaling and oligodendroglial abnormalities in the temporal cortex from patients with major depressive disorder. Mol Psychiatry 10: 309-322.
    • (2005) Mol Psychiatry , vol.10 , pp. 309-322
    • Aston, C.1    Jiang, L.2    Sokolov, B.P.3
  • 24
    • 79951630345 scopus 로고    scopus 로고
    • Gene expression signature is shared by patients with Alzheimer's disease and schizophrenia at the superior temporal gyrus
    • Horesh Y, Katsel P, Haroutunian V, Domany E, (2011) Gene expression signature is shared by patients with Alzheimer's disease and schizophrenia at the superior temporal gyrus. Eur J Neurol 18: 410-424.
    • (2011) Eur J Neurol , vol.18 , pp. 410-424
    • Horesh, Y.1    Katsel, P.2    Haroutunian, V.3    Domany, E.4
  • 25
    • 53649088131 scopus 로고    scopus 로고
    • Applications of next-generation sequencing technologies in functional genomics
    • Morozova O, Marra MA, (2008) Applications of next-generation sequencing technologies in functional genomics. Genomics 92: 255-264.
    • (2008) Genomics , vol.92 , pp. 255-264
    • Morozova, O.1    Marra, M.A.2
  • 26
    • 50649089207 scopus 로고    scopus 로고
    • RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays
    • Marioni JC, Mason CE, Mane SM, Stephens M, Gilad Y, (2008) RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays. Genome Res 18: 1509-1517.
    • (2008) Genome Res , vol.18 , pp. 1509-1517
    • Marioni, J.C.1    Mason, C.E.2    Mane, S.M.3    Stephens, M.4    Gilad, Y.5
  • 27
    • 47649124124 scopus 로고    scopus 로고
    • A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome
    • Sultan M, Schulz MH, Richard H, Magen A, Klingenhoff A, et al. (2008) A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome. Science 321: 956-960.
    • (2008) Science , vol.321 , pp. 956-960
    • Sultan, M.1    Schulz, M.H.2    Richard, H.3    Magen, A.4    Klingenhoff, A.5
  • 28
  • 29
    • 0036126121 scopus 로고    scopus 로고
    • Abnormalities of SNARE mechanism proteins in anterior frontal cortex in severe mental illness
    • Honer WG, Falkai P, Bayer TA, Xie J, Hu L, et al. (2002) Abnormalities of SNARE mechanism proteins in anterior frontal cortex in severe mental illness. Cereb Cortex 12: 349-356.
    • (2002) Cereb Cortex , vol.12 , pp. 349-356
    • Honer, W.G.1    Falkai, P.2    Bayer, T.A.3    Xie, J.4    Hu, L.5
  • 30
    • 0031958673 scopus 로고    scopus 로고
    • SNAP-25 deficit and hippocampal connectivity in schizophrenia
    • Young CE, Arima K, Xie J, Hu L, Beach TG, et al. (1998) SNAP-25 deficit and hippocampal connectivity in schizophrenia. Cereb Cortex 8: 261-268.
    • (1998) Cereb Cortex , vol.8 , pp. 261-268
    • Young, C.E.1    Arima, K.2    Xie, J.3    Hu, L.4    Beach, T.G.5
  • 31
    • 0030973411 scopus 로고    scopus 로고
    • Increased concentrations of presynaptic proteins in the cingulate cortex of subjects with schizophrenia
    • Gabriel SM, Haroutunian V, Powchik P, Honer WG, Davidson M, et al. (1997) Increased concentrations of presynaptic proteins in the cingulate cortex of subjects with schizophrenia. Arch Gen Psychiatry 54: 559-566.
    • (1997) Arch Gen Psychiatry , vol.54 , pp. 559-566
    • Gabriel, S.M.1    Haroutunian, V.2    Powchik, P.3    Honer, W.G.4    Davidson, M.5
  • 33
    • 46249104490 scopus 로고    scopus 로고
    • Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database
    • Allen NC, Bagade S, McQueen MB, Ioannidis JP, Kavvoura FK, et al. (2008) Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genet 40: 827-834.
    • (2008) Nat Genet , vol.40 , pp. 827-834
    • Allen, N.C.1    Bagade, S.2    McQueen, M.B.3    Ioannidis, J.P.4    Kavvoura, F.K.5
  • 34
    • 57649129041 scopus 로고    scopus 로고
    • Target identification for CNS diseases by transcriptional profiling
    • Altar CA, Vawter MP, Ginsberg SD, (2009) Target identification for CNS diseases by transcriptional profiling. Neuropsychopharmacology 34: 18-54.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 18-54
    • Altar, C.A.1    Vawter, M.P.2    Ginsberg, S.D.3
  • 35
    • 81955161247 scopus 로고    scopus 로고
    • The first decade and beyond of transcriptional profiling in schizophrenia
    • Sequeira PA, Martin MV, Vawter MP, (2012) The first decade and beyond of transcriptional profiling in schizophrenia. Neurobiol Dis 45: 23-36.
    • (2012) Neurobiol Dis , vol.45 , pp. 23-36
    • Sequeira, P.A.1    Martin, M.V.2    Vawter, M.P.3
  • 36
    • 34250868380 scopus 로고    scopus 로고
    • Variations in oligodendrocyte-related gene expression across multiple cortical regions: implications for the pathophysiology of schizophrenia
    • Haroutunian V, Katsel P, Dracheva S, Stewart DG, Davis KL, (2007) Variations in oligodendrocyte-related gene expression across multiple cortical regions: implications for the pathophysiology of schizophrenia. Int J Neuropsychopharmacol 10: 565-573.
    • (2007) Int J Neuropsychopharmacol , vol.10 , pp. 565-573
    • Haroutunian, V.1    Katsel, P.2    Dracheva, S.3    Stewart, D.G.4    Davis, K.L.5
  • 37
    • 78649775562 scopus 로고    scopus 로고
    • Enrichment map: a network-based method for gene-set enrichment visualization and interpretation
    • Merico D, Isserlin R, Stueker O, Emili A, Bader GD, (2010) Enrichment map: a network-based method for gene-set enrichment visualization and interpretation. PLoS One 5: e13984.
    • (2010) PLoS One , vol.5
    • Merico, D.1    Isserlin, R.2    Stueker, O.3    Emili, A.4    Bader, G.D.5
  • 38
    • 80052491357 scopus 로고    scopus 로고
    • Positive association of phencyclidine-responsive genes, PDE4A and PLAT, with schizophrenia
    • Deng X, Takaki H, Wang L, Kuroki T, Nakahara T, et al. (2011) Positive association of phencyclidine-responsive genes, PDE4A and PLAT, with schizophrenia. Am J Med Genet B Neuropsychiatr Genet 156B: 850-858.
    • (2011) Am J Med Genet B Neuropsychiatr Genet , vol.156 B , pp. 850-858
    • Deng, X.1    Takaki, H.2    Wang, L.3    Kuroki, T.4    Nakahara, T.5
  • 40
    • 67650161468 scopus 로고    scopus 로고
    • A role of complexin-lipid interactions in membrane fusion
    • Seiler F, Malsam J, Krause JM, Sollner TH, (2009) A role of complexin-lipid interactions in membrane fusion. FEBS Lett 583: 2343-2348.
    • (2009) FEBS Lett , vol.583 , pp. 2343-2348
    • Seiler, F.1    Malsam, J.2    Krause, J.M.3    Sollner, T.H.4
  • 41
    • 34249933061 scopus 로고    scopus 로고
    • How synaptotagmin promotes membrane fusion
    • Martens S, Kozlov MM, McMahon HT, (2007) How synaptotagmin promotes membrane fusion. Science 316: 1205-1208.
    • (2007) Science , vol.316 , pp. 1205-1208
    • Martens, S.1    Kozlov, M.M.2    McMahon, H.T.3
  • 43
    • 0028819440 scopus 로고
    • Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine
    • Edelmann L, Hanson PI, Chapman ER, Jahn R, (1995) Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine. Embo J 14: 224-231.
    • (1995) Embo J , vol.14 , pp. 224-231
    • Edelmann, L.1    Hanson, P.I.2    Chapman, E.R.3    Jahn, R.4
  • 44
    • 77954370364 scopus 로고    scopus 로고
    • Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels
    • Uriu Y, Kiyonaka S, Miki T, Yagi M, Akiyama S, et al. (2010) Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels. J Biol Chem 285: 21750-21767.
    • (2010) J Biol Chem , vol.285 , pp. 21750-21767
    • Uriu, Y.1    Kiyonaka, S.2    Miki, T.3    Yagi, M.4    Akiyama, S.5
  • 46
    • 77949542049 scopus 로고    scopus 로고
    • A novel mechanism and treatment target for presynaptic abnormalities in specific striatal regions in schizophrenia
    • Barakauskas VE, Beasley CL, Barr AM, Ypsilanti AR, Li HY, et al. (2010) A novel mechanism and treatment target for presynaptic abnormalities in specific striatal regions in schizophrenia. Neuropsychopharmacology 35: 1226-1238.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1226-1238
    • Barakauskas, V.E.1    Beasley, C.L.2    Barr, A.M.3    Ypsilanti, A.R.4    Li, H.Y.5
  • 47
    • 68049142991 scopus 로고    scopus 로고
    • Upregulation of NRG-1 and VAMP-1 in human brain aggregates exposed to clozapine
    • Chana G, Lucero G, Salaria S, Lozach J, Du P, et al. (2009) Upregulation of NRG-1 and VAMP-1 in human brain aggregates exposed to clozapine. Schizophr Res 113: 273-276.
    • (2009) Schizophr Res , vol.113 , pp. 273-276
    • Chana, G.1    Lucero, G.2    Salaria, S.3    Lozach, J.4    Du, P.5
  • 48
    • 78449276430 scopus 로고    scopus 로고
    • Differential expression of presynaptic genes in a rat model of postnatal hypoxia: relevance to schizophrenia
    • Sommer JU, Schmitt A, Heck M, Schaeffer EL, Fendt M, et al. (2010) Differential expression of presynaptic genes in a rat model of postnatal hypoxia: relevance to schizophrenia. Eur Arch Psychiatry Clin Neurosci 260 (Suppl 2): S81-89.
    • (2010) Eur Arch Psychiatry Clin Neurosci , vol.260 , Issue.SUPPL. 2
    • Sommer, J.U.1    Schmitt, A.2    Heck, M.3    Schaeffer, E.L.4    Fendt, M.5
  • 49
    • 0036892039 scopus 로고    scopus 로고
    • Antipsychotic drug treatment induces differential gene expression in the rat cortex
    • Kontkanen O, Toronen P, Lakso M, Wong G, Castren E, (2002) Antipsychotic drug treatment induces differential gene expression in the rat cortex. J Neurochem 83: 1043-1053.
    • (2002) J Neurochem , vol.83 , pp. 1043-1053
    • Kontkanen, O.1    Toronen, P.2    Lakso, M.3    Wong, G.4    Castren, E.5
  • 50
    • 0033006832 scopus 로고    scopus 로고
    • Alterations in synaptic proteins and their encoding mRNAs in prefrontal cortex in schizophrenia: a possible neurochemical basis for 'hypofrontality'
    • Karson CN, Mrak RE, Schluterman KO, Sturner WQ, Sheng JG, et al. (1999) Alterations in synaptic proteins and their encoding mRNAs in prefrontal cortex in schizophrenia: a possible neurochemical basis for 'hypofrontality'. Mol Psychiatry 4: 39-45.
    • (1999) Mol Psychiatry , vol.4 , pp. 39-45
    • Karson, C.N.1    Mrak, R.E.2    Schluterman, K.O.3    Sturner, W.Q.4    Sheng, J.G.5
  • 51
    • 56649102089 scopus 로고    scopus 로고
    • Genomic convergence analysis of schizophrenia: mRNA sequencing reveals altered synaptic vesicular transport in post-mortem cerebellum
    • Mudge J, Miller NA, Khrebtukova I, Lindquist IE, May GD, et al. (2008) Genomic convergence analysis of schizophrenia: mRNA sequencing reveals altered synaptic vesicular transport in post-mortem cerebellum. PLoS One 3: e3625.
    • (2008) PLoS One , vol.3
    • Mudge, J.1    Miller, N.A.2    Khrebtukova, I.3    Lindquist, I.E.4    May, G.D.5
  • 52
    • 33745698337 scopus 로고    scopus 로고
    • Critical appraisal of DNA microarrays in psychiatric genomics
    • Mirnics K, Levitt P, Lewis DA, (2006) Critical appraisal of DNA microarrays in psychiatric genomics. Biol Psychiatry 60: 163-176.
    • (2006) Biol Psychiatry , vol.60 , pp. 163-176
    • Mirnics, K.1    Levitt, P.2    Lewis, D.A.3
  • 53
    • 55049084761 scopus 로고    scopus 로고
    • Coregulation of genes in the mouse brain following treatment with clozapine, haloperidol, or olanzapine implicates altered potassium channel subunit expression in the mechanism of antipsychotic drug action
    • Duncan CE, Chetcuti AF, Schofield PR, (2008) Coregulation of genes in the mouse brain following treatment with clozapine, haloperidol, or olanzapine implicates altered potassium channel subunit expression in the mechanism of antipsychotic drug action. Psychiatr Genet 18: 226-239.
    • (2008) Psychiatr Genet , vol.18 , pp. 226-239
    • Duncan, C.E.1    Chetcuti, A.F.2    Schofield, P.R.3
  • 54
    • 0346100528 scopus 로고    scopus 로고
    • Differential effects of long-term treatment with clozapine or haloperidol on GABAA receptor binding and GAD67 expression
    • Zink M, Schmitt A, May B, Muller B, Demirakca T, et al. (2004) Differential effects of long-term treatment with clozapine or haloperidol on GABAA receptor binding and GAD67 expression. Schizophr Res 66: 151-157.
    • (2004) Schizophr Res , vol.66 , pp. 151-157
    • Zink, M.1    Schmitt, A.2    May, B.3    Muller, B.4    Demirakca, T.5
  • 55
    • 0034651036 scopus 로고    scopus 로고
    • Multiple functions of the myelin-associated glycoprotein MAG (siglec-4a) in formation and maintenance of myelin
    • Schachner M, Bartsch U, (2000) Multiple functions of the myelin-associated glycoprotein MAG (siglec-4a) in formation and maintenance of myelin. Glia 29: 154-165.
    • (2000) Glia , vol.29 , pp. 154-165
    • Schachner, M.1    Bartsch, U.2
  • 56
    • 3142745187 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress
    • Prabakaran S, Swatton JE, Ryan MM, Huffaker SJ, Huang JT, et al. (2004) Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress. Mol Psychiatry 9: 684-697, 643.
    • (2004) Mol Psychiatry , vol.9
    • Prabakaran, S.1    Swatton, J.E.2    Ryan, M.M.3    Huffaker, S.J.4    Huang, J.T.5
  • 57
    • 33646568509 scopus 로고    scopus 로고
    • Decrease in creatine kinase messenger RNA expression in the hippocampus and dorsolateral prefrontal cortex in bipolar disorder
    • MacDonald ML, Naydenov A, Chu M, Matzilevich D, Konradi C, (2006) Decrease in creatine kinase messenger RNA expression in the hippocampus and dorsolateral prefrontal cortex in bipolar disorder. Bipolar Disord 8: 255-264.
    • (2006) Bipolar Disord , vol.8 , pp. 255-264
    • MacDonald, M.L.1    Naydenov, A.2    Chu, M.3    Matzilevich, D.4    Konradi, C.5
  • 58
    • 0037009130 scopus 로고    scopus 로고
    • Molecular chaperones as essential mediators of mitochondrial biogenesis
    • Voos W, Rottgers K, (2002) Molecular chaperones as essential mediators of mitochondrial biogenesis. Biochim Biophys Acta 1592: 51-62.
    • (2002) Biochim Biophys Acta , vol.1592 , pp. 51-62
    • Voos, W.1    Rottgers, K.2
  • 59
    • 0036672615 scopus 로고    scopus 로고
    • Specificity of 14-3-3 isoform dimer interactions and phosphorylation
    • Aitken A, Baxter H, Dubois T, Clokie S, Mackie S, et al. (2002) Specificity of 14-3-3 isoform dimer interactions and phosphorylation. Biochem Soc Trans 30: 351-360.
    • (2002) Biochem Soc Trans , vol.30 , pp. 351-360
    • Aitken, A.1    Baxter, H.2    Dubois, T.3    Clokie, S.4    Mackie, S.5
  • 60
    • 0033647377 scopus 로고    scopus 로고
    • A genome-wide autosomal screen for schizophrenia susceptibility loci in 71 families with affected siblings: support for loci on chromosome 10p and 6
    • Schwab SG, Hallmayer J, Albus M, Lerer B, Eckstein GN, et al. (2000) A genome-wide autosomal screen for schizophrenia susceptibility loci in 71 families with affected siblings: support for loci on chromosome 10p and 6. Mol Psychiatry 5: 638-649.
    • (2000) Mol Psychiatry , vol.5 , pp. 638-649
    • Schwab, S.G.1    Hallmayer, J.2    Albus, M.3    Lerer, B.4    Eckstein, G.N.5
  • 61
    • 41449106352 scopus 로고    scopus 로고
    • Physiological function of the DCX family in brain development
    • Koizumi H, (2007) Physiological function of the DCX family in brain development. Seikagaku 79: 1134-1139.
    • (2007) Seikagaku , vol.79 , pp. 1134-1139
    • Koizumi, H.1
  • 62
    • 0034533439 scopus 로고    scopus 로고
    • Doublecortin-like kinase is associated with microtubules in neuronal growth cones
    • Burgess HA, Reiner O, (2000) Doublecortin-like kinase is associated with microtubules in neuronal growth cones. Mol Cell Neurosci 16: 529-541.
    • (2000) Mol Cell Neurosci , vol.16 , pp. 529-541
    • Burgess, H.A.1    Reiner, O.2
  • 63
    • 0033613840 scopus 로고    scopus 로고
    • CPG16, a novel protein serine/threonine kinase downstream of cAMP-dependent protein kinase
    • Silverman MA, Benard O, Jaaro H, Rattner A, Citri Y, et al. (1999) CPG16, a novel protein serine/threonine kinase downstream of cAMP-dependent protein kinase. J Biol Chem 274: 2631-2636.
    • (1999) J Biol Chem , vol.274 , pp. 2631-2636
    • Silverman, M.A.1    Benard, O.2    Jaaro, H.3    Rattner, A.4    Citri, Y.5
  • 64
    • 0033571475 scopus 로고    scopus 로고
    • KIAA0369, doublecortin-like kinase, is expressed during brain development
    • Burgess HA, Martinez S, Reiner O, (1999) KIAA0369, doublecortin-like kinase, is expressed during brain development. J Neurosci Res 58: 567-575.
    • (1999) J Neurosci Res , vol.58 , pp. 567-575
    • Burgess, H.A.1    Martinez, S.2    Reiner, O.3
  • 65
    • 77953600210 scopus 로고    scopus 로고
    • Silencing of the microtubule-associated proteins doublecortin-like and doublecortin-like kinase-long induces apoptosis in neuroblastoma cells
    • Verissimo CS, Molenaar JJ, Meerman J, Puigvert JC, Lamers F, et al. (2010) Silencing of the microtubule-associated proteins doublecortin-like and doublecortin-like kinase-long induces apoptosis in neuroblastoma cells. Endocr Relat Cancer 17: 399-414.
    • (2010) Endocr Relat Cancer , vol.17 , pp. 399-414
    • Verissimo, C.S.1    Molenaar, J.J.2    Meerman, J.3    Puigvert, J.C.4    Lamers, F.5
  • 66
    • 34250827871 scopus 로고    scopus 로고
    • Oligodendroglial abnormalities in schizophrenia, mood disorders and substance abuse. Comorbidity, shared traits, or molecular phenocopies?
    • Sokolov BP, (2007) Oligodendroglial abnormalities in schizophrenia, mood disorders and substance abuse. Comorbidity, shared traits, or molecular phenocopies? Int J Neuropsychopharmacol 10: 547-555.
    • (2007) Int J Neuropsychopharmacol , vol.10 , pp. 547-555
    • Sokolov, B.P.1
  • 67
    • 0023389399 scopus 로고
    • Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin
    • Nave KA, Lai C, Bloom FE, Milner RJ, (1987) Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin. Proc Natl Acad Sci U S A 84: 5665-5669.
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 5665-5669
    • Nave, K.A.1    Lai, C.2    Bloom, F.E.3    Milner, R.J.4
  • 68
    • 0036006720 scopus 로고    scopus 로고
    • Oligodendrocytes expressing exclusively the DM20 isoform of the proteolipid protein gene: myelination and development
    • Sporkel O, Uschkureit T, Bussow H, Stoffel W, (2002) Oligodendrocytes expressing exclusively the DM20 isoform of the proteolipid protein gene: myelination and development. Glia 37: 19-30.
    • (2002) Glia , vol.37 , pp. 19-30
    • Sporkel, O.1    Uschkureit, T.2    Bussow, H.3    Stoffel, W.4
  • 69
    • 3142664532 scopus 로고    scopus 로고
    • Embryonic expression of the soma-restricted products of the myelin proteolipid gene in motor neurons and muscle
    • Jacobs EC, Bongarzone ER, Campagnoni CW, Campagnoni AT, (2004) Embryonic expression of the soma-restricted products of the myelin proteolipid gene in motor neurons and muscle. Neurochem Res 29: 997-1002.
    • (2004) Neurochem Res , vol.29 , pp. 997-1002
    • Jacobs, E.C.1    Bongarzone, E.R.2    Campagnoni, C.W.3    Campagnoni, A.T.4
  • 70
    • 69849114213 scopus 로고    scopus 로고
    • Myelin proteomics: molecular anatomy of an insulating sheath
    • Jahn O, Tenzer S, Werner HB, (2009) Myelin proteomics: molecular anatomy of an insulating sheath. Mol Neurobiol 40: 55-72.
    • (2009) Mol Neurobiol , vol.40 , pp. 55-72
    • Jahn, O.1    Tenzer, S.2    Werner, H.B.3
  • 71
    • 0031025729 scopus 로고    scopus 로고
    • Conservation of topology, but not conformation, of the proteolipid proteins of the myelin sheath
    • Gow A, Gragerov A, Gard A, Colman DR, Lazzarini RA, (1997) Conservation of topology, but not conformation, of the proteolipid proteins of the myelin sheath. J Neurosci 17: 181-189.
    • (1997) J Neurosci , vol.17 , pp. 181-189
    • Gow, A.1    Gragerov, A.2    Gard, A.3    Colman, D.R.4    Lazzarini, R.A.5
  • 72
    • 85081766327 scopus 로고    scopus 로고
    • Synaptic changes in the brain of subjects with schizophrenia
    • Faludi G, Mirnics K, (2011) Synaptic changes in the brain of subjects with schizophrenia. Int J Dev Neurosci 2011: 4.
    • (2011) Int J Dev Neurosci , vol.2011 , pp. 4
    • Faludi, G.1    Mirnics, K.2
  • 75
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: discovering splice junctions with RNA-Seq
    • Trapnell C, Pachter L, Salzberg SL, (2009) TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25: 1105-1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 76
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead B, Trapnell C, Pop M, Salzberg SL, (2009) Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10: R25.
    • (2009) Genome Biol , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 78
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • Trapnell C, Williams BA, Pertea G, Mortazavi A, Kwan G, et al. (2010) Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol 28: 511-515.
    • (2010) Nat Biotechnol , vol.28 , pp. 511-515
    • Trapnell, C.1    Williams, B.A.2    Pertea, G.3    Mortazavi, A.4    Kwan, G.5
  • 80
    • 78650511568 scopus 로고    scopus 로고
    • Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia
    • Santarelli DM, Beveridge NJ, Tooney PA, Cairns MJ, (2011) Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia. Biol Psychiatry 69: 180-187.
    • (2011) Biol Psychiatry , vol.69 , pp. 180-187
    • Santarelli, D.M.1    Beveridge, N.J.2    Tooney, P.A.3    Cairns, M.J.4
  • 81
  • 82
    • 38449101120 scopus 로고    scopus 로고
    • Integration of biological networks and gene expression data using Cytoscape
    • Cline MS, Smoot M, Cerami E, Kuchinsky A, Landys N, et al. (2007) Integration of biological networks and gene expression data using Cytoscape. Nat Protoc 2: 2366-2382.
    • (2007) Nat Protoc , vol.2 , pp. 2366-2382
    • Cline, M.S.1    Smoot, M.2    Cerami, E.3    Kuchinsky, A.4    Landys, N.5


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