The synapsins: Beyond the regulation of neurotransmitter release

Cellular and Molecular Life Sciences

Volumn 59, Issue 4, 2002, Pages 589-595

  Ferreira, A ^a   Rapoport, M ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Institute for Neuroscience   (United States)

Author keywords

Axonal differentiation; Mental diseases; Neurite elongation; Synapsins; Synaptogenesis

Indexed keywords

NEUROTRANSMITTER; PHOSPHOPROTEIN; SYNAPSIN;

ACTIN FILAMENT; CELL DIFFERENTIATION; MENTAL DISEASE; MOLECULAR RECOGNITION; MULTIGENE FAMILY; NERVE GROWTH; NEUROTRANSMITTER RELEASE; NONHUMAN; PROTEIN PHOSPHORYLATION; REVIEW; SYNAPSE VESICLE; SYNAPTOGENESIS;

ANIMALS; CENTRAL NERVOUS SYSTEM; HIPPOCAMPUS; MODELS, NEUROLOGICAL; NEURITES; NEUROTRANSMITTER AGENTS; SYNAPSES; SYNAPSINS; SYNAPTIC VESICLES;

EID: 0036237621     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-002-8451-5     Document Type: Review

References (70)

1. Developmental mechanisms that generate precise patterns of neuronal connectivity
2. Synaptic structure and development: The neuromuscular junction
3. From contact to connection: Early events during synaptogenesis
4. Adenosin 3′,5′-monophosphate-independent phosphorlyation of a specific protein in synaptic membrane fractions from rat cerebrum
5. Regulation of endogenous phosphorylation of specific proteins in synaptic membrane fractions from rat brain by adenosine 3′5′-monophosphate
6. Purification and characterization of protein IIb, a mammalian brain phosphoprotein
7. Genes for synapsin I, a neuronal phosphoprotein, map to conserved regions of human and murine X chromosomes
8. A third member of the synapsin gene family
9. Molecular evolution of the synapsin gene family
10. 2+
11. Adenosine 3′:5′-monophosphate-regulated phosphoprotein system of neuronal membranes. I. Solubilization, purification and some properties of an endogenous phosphoprotein
12. Distribution of protein I in mammalian brain as determined by a detergent-based radioimmunoassay
13. Similarities between protein IIIa and protein IIIb, two prominent synaptic vesicles-associated phosphoproteins
14. Synapsin I (protein I), a nerve terminal-specific phosphoprotein: I. Its general distribution in synapses of the central and peripheral nervous system demonstrated by immunofluorescence in frozen and plastic sections
15. The synaptic vesicle proteins synapsin I and (synaptophysin p38) are concentrated in both efferent and afferent nerve endings of the skeletal muscle
16. Synapsin I-like immunoreactivity in nerve fibers associated with lingual taste buds of the rat
17. The synapsins
18. Synapsins: Mosaic of shared and individual domains in a family of synaptic vesicle phosphoproteins
19. Synapsins as regulators of neurotransmitter release
20. A phosphoswitch controls the dynamic association of synapsins with synaptic vesicles
21. Synapsin I is structurally homologous to ATP-utilizing enzymes
22. 2+
23. Homo- and heterodimerization of synapsins
24. Molecular biology of synaptic vesicle associated proteins
25. Interaction of synapsin I with small vesicles: Distinct sites in synapsin I bind to vesicle phospholipids and vesicular proteins
26. Proteins of synaptic vesicles involved in exocytosis and membrane recycling
27. Synaptic vesicle phosphoproteins and regulation of synaptic function
28. The synapsins and the regulation of synaptic function
29. Structure and function of the synapsins
30. Genetic analysis of neurotransmitter release at the synapse
31. Synaptic vesicle exocytosis: Molecules and models
32. Synapsin I, an actin-binding protein regulating synaptic vesicle traffic in the nerve terminal
33. Synaptic vesicle phosphoproteins and regulation of synaptic function
34. Sustained neurotransmitter release: New molecular clues
35. The structure of the synapses
36. Distinct pools in neurotransmitter release
37. Ontogeny of synaptic phosphoproteins in brain
38. Temporal onset of synapsin I gene expression coincides with neuronal differentiation during the development of the nervous system
39. Synapsin III: Developmental expression, subcellular localization and role in axonal elongation
40. Synapsin I in nerve terminals. Selective association with small synaptic vesicles
41. Localization of synapsin I at the frog neuromuscular junction
42. The distribution of synapsin I and synaptophysin in hippocampal neurons in culture
43. Subcellular distribution in cerebral cortex of two proteins phosphorylated by a cAMP-dependent protein kinase
44. Synapsin I (Protein I), a nerve terminal-specific phosphoprotein III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation
45. Characterization of synapsin I binding to small synaptic vesicles
46. Synapsin II: Mapping of a domain in the NH2 terminal region which binds to small synaptic vesicles
47. Induction of formation of presynaptic terminals in neuroblastoma cells by synapsin IIb
48. Accelerated structural maturation induced by synapsin I at developing neuromuscular synapses of Xenopus laevis
49. Exogenous synapsin I promotes functional maturation of developing neuromuscular synapses
50. Exogenous synapsin I promotes functional maturation of developing neuromuscular synapses
51. Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice
52. Synapsin I deficiency results in the structural change in the presynaptic terminals in the murine nervous system
53. Essential functions of synapsin I and II in synaptic vesicle regulation
54. Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice
55. Distinct roles of synapsin I and synapsin II during neuronal development
56. Postsynaptic element contributes to the delay in synaptogenesis in synapsin I deficient neurons
57. Suppression of synapsin II inhibits the formation and maintenance of synapses in hippocampal culture
58. Aberrant neurites and synaptic vesicle protein deficiency in synapsin II-depleted neurons
59. Developmental changes of synapsin I subcellular localization in rat cerebellar neurons
60. The establishment of polarity by hippocampal neurons in culture
61. Hippocampal neurons in low density culture
62. Remodeling of cytoskeletal architecture of neuronal cells induced by synapsin
63. The expression of acetylated microtubules during axonal and dendritic growth in cerebellar macroneurons which develop in vitro
64. Microtubule formation and neurite growth in cerebellar macroneurons which develop in vitro: Evidence for the involvement of the microtubule-associated proteins, MAP-1a, HMW-MAP-2 and tau
65. Cytoskeletal dynamics and nerve growth
66. The role of local actin instability in axon formation
67. Characterization of synapsin I fragments produced by cysteine-specific cleavage: A study of their interactions with F-actin
68. Synapsin I is a microtubule-bundling protein
69. Synapsin IIa bundles actin filaments
70. Synapsin I: An actin-bundling protein under phosphorylation control