메뉴 건너뛰기




Volumn 31, Issue 12, 2012, Pages 1475-1483

Cilia, adenomatous polyposis coli and associated diseases

Author keywords

adenomatous polyposis coli; cilia; familial adenomatous polyposis; mutation

Indexed keywords

ADENOSINE TRIPHOSPHATASE; APC PROTEIN; BETA CATENIN; PLATELET DERIVED GROWTH FACTOR; WNT PROTEIN;

EID: 84860411147     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.351     Document Type: Review
Times cited : (10)

References (68)
  • 1
    • 0022322468 scopus 로고
    • The immotile-cilia syndrome: A microtubuleassociated defect
    • Afzelius BA. (1985). The immotile-cilia syndrome: a microtubuleassociated defect. CRC Crit Rev Biochem 19: 63-87.
    • (1985) CRC Crit Rev Biochem , vol.19 , pp. 63-87
    • Afzelius, B.A.1
  • 2
    • 0032568802 scopus 로고    scopus 로고
    • Regulation of Armadillo by a Drosophila APC inhibits neuronal apoptotis during retinal development
    • DOI 10.1016/S0092-8674(00)81461-0
    • Ahmed Y, Hayashi S, Levine A, Wieschaus E. (1998). Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal. Dev Cell 93: 1171-1182. (Pubitemid 28307422)
    • (1998) Cell , vol.93 , Issue.7 , pp. 1171-1182
    • Ahmed, Y.1    Hayashi, S.2    Levine, A.3    Wieschaus, E.4
  • 3
    • 70449646115 scopus 로고    scopus 로고
    • The dynamic cilium in human diseases
    • Angelo AD, Franco B. (2009). The dynamic cilium in human diseases. Pathogenetics 2: 3.
    • (2009) Pathogenetics , vol.2 , pp. 3
    • Angelo, A.D.1    Franco, B.2
  • 4
    • 35648988947 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC): A multi-functional tumor suppressor gene
    • DOI 10.1242/jcs.03485
    • Aoki K, Taketo MM. (2007). Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene. J Cell Sci 120: 3327-3335. (Pubitemid 350028340)
    • (2007) Journal of Cell Science , vol.120 , Issue.19 , pp. 3327-3335
    • Aoki, K.1    Taketo, M.M.2
  • 6
    • 0029928160 scopus 로고    scopus 로고
    • APC gene: Database of germline and somatic mutations in human tumors and cell lines
    • DOI 10.1093/nar/24.1.121
    • Beroud C, Soussi T. (1996). APC gene: database of germline and somatic mutations in human tumors and cell lines. Nucleic Acids Res 24: 121-124. (Pubitemid 26085747)
    • (1996) Nucleic Acids Research , vol.24 , Issue.1 , pp. 121-124
    • Beroud, C.1    Soussi, T.2
  • 8
    • 0036270763 scopus 로고    scopus 로고
    • The subcellular destinations of APC proteins
    • DOI 10.1038/nrm806
    • Bienz M. (2002). The subcellular destinations of APC proteins. Nat Rev Mol Cell Biol 3: 328-338. (Pubitemid 34619267)
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , Issue.5 , pp. 328-338
    • Bienz, M.1
  • 9
    • 33751526052 scopus 로고    scopus 로고
    • The roles of cilia in developmental disorders and disease
    • DOI 10.1242/dev.02595
    • Bisgrove BW, Yost HJ. (2006). The roles of cilia in developmental disorders and disease. Development 133: 4131-4143. (Pubitemid 44830657)
    • (2006) Development , vol.133 , Issue.21 , pp. 4131-4143
    • Bisgrove, B.W.1    Yost, H.J.2
  • 11
    • 0035034603 scopus 로고    scopus 로고
    • Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development
    • Brault V, Moore R, Kutsch S, Ishibashi M, Rowitch DH, McMahon AP et al. (2001). Inactivation of the β-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development 128: 1253-1264. (Pubitemid 32409648)
    • (2001) Development , vol.128 , Issue.8 , pp. 1253-1264
    • Brault, V.1    Moore, R.2    Kutsch, S.3    Ishibashi, M.4    Rowitch, D.H.5    McMahon, A.P.6    Sommer, L.7    Boussadia, O.8    Kemler, R.9
  • 12
    • 0028905406 scopus 로고
    • Familial adenomatous polyposis: Desmoid tumours and lack of ophthalmic lesions (CHRPE) associated with APC mutations beyond codon 1444
    • Caspari R, Olschwang S, Friedl W, Mandl M, Boisson C, Böker T et al. (1995). Familial adenomatous polyposis: desmoid tumours and lack of ophthalmic lesions (CHRPE) associated with APC mutations beyond codon 1444. Hum Mol Genet 4: 337-340.
    • (1995) Hum Mol Genet , vol.4 , pp. 337-340
    • Caspari, R.1    Olschwang, S.2    Friedl, W.3    Mandl, M.4    Boisson, C.5    Böker, T.6
  • 13
    • 1342329609 scopus 로고    scopus 로고
    • Cilia, primary ciliary dyskinesia and molecular genetics
    • DOI 10.1016/j.prrv.2003.09.005
    • Chodhari R, Mitchison HM, Meeks M. (2004). Cilia, primary ciliary dyskinesia and molecular genetics. Paediatr Respir Rev 5: 69-76. (Pubitemid 38256168)
    • (2004) Paediatric Respiratory Reviews , vol.5 , Issue.1 , pp. 69-76
    • Chodhari, R.1    Mitchison, H.M.2    Meeks, M.3
  • 15
    • 27944469172 scopus 로고    scopus 로고
    • An incredible decade for the primary cilia: A look at a once-forgotten organelle
    • Davenport JR, Yoder BK. (2005). An incredible decade for the primary cilia: a look at a once-forgotten organelle. Am J Renal Physiol 289: 1159-1169.
    • (2005) Am J Renal Physiol , vol.289 , pp. 1159-1169
    • Davenport, J.R.1    Yoder, B.K.2
  • 16
    • 0029913359 scopus 로고    scopus 로고
    • Colorectal polyp counts and cancer risk in familial adenomatous polyposis
    • DOI 10.1053/gast.1996.v110.pm8612989
    • Debinski HS, Love S, Spigelman AD, Phillips RK. (1996). Colorectal polyp counts and risk in familia adenomatous polyposis. Gastroenterology 110: 1028-1030. (Pubitemid 26113740)
    • (1996) Gastroenterology , vol.110 , Issue.4 , pp. 1028-1030
    • Debinski, H.S.1    Love, S.2    Spigelman, A.D.3    Phillips, R.K.S.4
  • 20
    • 0036224749 scopus 로고    scopus 로고
    • The APC gene in colorectal cancer
    • DOI 10.1016/S0959-8049(02)00040-0, PII S0959804902000400
    • Fodde R. (2002). The APC gene in colorectal cancer. Eur J Cancer 38: 867-871. (Pubitemid 34442313)
    • (2002) European Journal of Cancer , vol.38 , Issue.7 , pp. 867-871
    • Fodde, R.1
  • 22
    • 77951207867 scopus 로고    scopus 로고
    • Wnt signaling in development and disease
    • Freese JL, Pino D, Pleasure SJ. (2010). Wnt signaling in development and disease. Neurobiol Dis 38: 148-153.
    • (2010) Neurobiol Dis , vol.38 , pp. 148-153
    • Freese, J.L.1    Pino, D.2    Pleasure, S.J.3
  • 24
    • 35648985644 scopus 로고    scopus 로고
    • Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response
    • Gerdes JM, Liu Y, Zaghloul NA, Leitch CC, Lawson SS, Kato M et al. (2007). Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response. Nat Genet 39: 1350-1136.
    • (2007) Nat Genet , vol.39 , pp. 1350-1136
    • Gerdes, J.M.1    Liu, Y.2    Zaghloul, N.A.3    Leitch, C.C.4    Lawson, S.S.5    Kato, M.6
  • 26
    • 67649359526 scopus 로고    scopus 로고
    • Gardner's syndrome (familial adenomatous polyposis): A cilia-related disorder
    • Gömez García EB, Knoers NV. (2009). Gardner's syndrome (familial adenomatous polyposis): a cilia-related disorder. Lancet Oncol 10: 727-735.
    • (2009) Lancet Oncol , vol.10 , pp. 727-735
    • Gömez García, E.B.1    Knoers, N.V.2
  • 27
    • 0025938038 scopus 로고
    • Identification and characterization of the familial adenomatous polyposis coli gene
    • Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, Albertsen H et al. (1991). Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66: 589-600.
    • (1991) Cell , vol.66 , pp. 589-600
    • Groden, J.1    Thliveris, A.2    Samowitz, W.3    Carlson, M.4    Gelbert, L.5    Albertsen, H.6
  • 29
    • 0022810104 scopus 로고
    • Brief clinical report: Gardner syndrome in a man with an interstitial deletion of 5q
    • Herrera L, Kakati S, Gibas L, Pietrzak E, Sandbert A. (1986). Brief clinical report: Gardner syndrome in a man with an interstiiial deletion of 5a. Am J Med Genet 25: 473-476. (Pubitemid 16008369)
    • (1986) American Journal of Medical Genetics , vol.25 , Issue.3 , pp. 473-476
    • Herrera, L.1    Kakati, S.2    Gibas, L.3
  • 31
    • 31644442906 scopus 로고    scopus 로고
    • Signaling from Smo to Ci/Gli: Conservation and divergence of Hedgehog pathways from Drosophila to vertebrates
    • DOI 10.1242/dev.02169
    • Huangfu D, Anderson KV. (2006). Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates. Development 133: 3-14. (Pubitemid 43169315)
    • (2006) Development , vol.133 , Issue.1 , pp. 3-14
    • Huangfu, D.1    Anderson, K.V.2
  • 32
    • 0034688150 scopus 로고    scopus 로고
    • The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase
    • Ishidate T, Matsumine A, Toyoshima K, Akiyama T. (2000). The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase. Oncogene 19: 365-372. (Pubitemid 30077336)
    • (2000) Oncogene , vol.19 , Issue.3 , pp. 365-372
    • Ishidate, T.1    Matsumine, A.2    Toyoshima, K.3    Akiyama, T.4
  • 33
    • 0036226855 scopus 로고    scopus 로고
    • Identification of a link between the tumour suppressor APC and the kinesin superfamily
    • DOI 10.1038/ncb779
    • Jimbo T, Kawasaki Y, Koyama R, Sato R, Takada S, Haraguchi K et al. (2002). Identifi cation of a link between the tumour suppressor APC and the kinesin superfamily. Nat Cell Biol 4: 323-327. (Pubitemid 34308860)
    • (2002) Nature Cell Biology , vol.4 , Issue.4 , pp. 323-327
    • Jimbo, T.1    Kawasaki, Y.2    Koyama, R.3    Sato, R.4    Takada, S.5    Haraguchi, K.6    Akiyama, T.7
  • 37
    • 0027185632 scopus 로고
    • From cadherins to catenins: Cytoplasmic protein interactions and regulation of cell adhesion
    • DOI 10.1016/0168-9525(93)90250-L
    • Kemler R. (1993). From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet 9: 317-321. (Pubitemid 23271755)
    • (1993) Trends in Genetics , vol.9 , Issue.9 , pp. 317-321
    • Kemler, R.1
  • 39
    • 38849141755 scopus 로고    scopus 로고
    • Ciliary syndromes and treatment
    • DOI 10.1016/j.prp.2007.10.013, PII S0344033807002506
    • Klysik M. (2008). Ciliary syndromes and treatment. Pathol Res Pract 204: 77-88. (Pubitemid 351189056)
    • (2008) Pathology Research and Practice , vol.204 , Issue.2 , pp. 77-88
    • Klysik, M.1
  • 41
    • 68649098302 scopus 로고    scopus 로고
    • The primary cilia as a cellular signaling center: Lessons from disease
    • Lancaster MA, Gleeson JG. (2009). The primary cilia as a cellular signaling center: lessons from disease. Curr Opin Genet Dev 19: 220-229.
    • (2009) Curr Opin Genet Dev , vol.19 , pp. 220-229
    • Lancaster, M.A.1    Gleeson, J.G.2
  • 42
    • 0001827184 scopus 로고
    • Four cases of retinitis pigmentosa occurring in the same family accompanied by general imperfection of development
    • Laurence JZ, Moon RC. (1866). Four cases of retinitis pigmentosa occurring in the same family accompanied by general imperfection of development. Ophthalmol Rev 2: 32-41.
    • (1866) Ophthalmol Rev , vol.2 , pp. 32-41
    • Laurence, J.Z.1    Moon, R.C.2
  • 43
    • 56049120376 scopus 로고    scopus 로고
    • All along the watchtower: Is the cilium a tumor suppressor organelle?
    • Mans DA, Voest EE, Giles RH. (2008). All along the watchtower: is the cilium a tumor suppressor organelle? Biochim Biophys Acta 1786: 114-125.
    • (2008) Biochim Biophys Acta , vol.1786 , pp. 114-125
    • Mans, D.A.1    Voest, E.E.2    Giles, R.H.3
  • 45
    • 84860420701 scopus 로고    scopus 로고
    • The primary cilia in cell signaling and cancer
    • Michaud EJ, Yoder BK. (2006). The primary cilia in cell signaling and cancer. Cancer Res 6: 6646-6468.
    • (2006) Cancer Res , vol.6 , pp. 6646-6468
    • Michaud, E.J.1    Yoder, B.K.2
  • 46
    • 0034614936 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells
    • Mimori-Kiousue Y, Shiina N, Tsukita S. (2000). Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells. J Cell Biol 48: 505-518.
    • (2000) J Cell Biol , vol.48 , pp. 505-518
    • Mimori-Kiousue, Y.1    Shiina, N.2    Tsukita, S.3
  • 47
    • 42549132671 scopus 로고    scopus 로고
    • Difference in characteristics of APC mutations between colonic and extracolonic tumors of FAP patients: Variations with phenotype
    • DOI 10.1002/ijc.23390
    • Miyaki M, Yamaguchi T, Iijima T, Takahashi K, Matsumoto H, Yasutome M et al. (2008). Difference in characteristics of APC mutations between colonic and extracolonic tumors of FAP patients: variations with phenotype. Int J Cancer 122: 2491-2497. (Pubitemid 351590481)
    • (2008) International Journal of Cancer , vol.122 , Issue.11 , pp. 2491-2497
    • Miyaki, M.1    Yamaguchi, T.2    Iijima, T.3    Takahashi, K.4    Matsumoto, H.5    Yasutome, M.6    Funata, N.7    Mori, T.8
  • 48
    • 0026894053 scopus 로고
    • Somatic mutations of the APC gene in colorectal tumors: Mutation cluster region in the APC gene
    • Miyoshi Y, Nagase H, Ando H, Horii A, Ichii S, Nakatsuru S et al. (1992). Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Hum Mol Genet 1: 229-233.
    • (1992) Hum Mol Genet , vol.1 , pp. 229-233
    • Miyoshi, Y.1    Nagase, H.2    Ando, H.3    Horii, A.4    Ichii, S.5    Nakatsuru, S.6
  • 50
    • 1942512288 scopus 로고    scopus 로고
    • Role of APC and DNA mismatch repair genes in the development of colorectal cancers
    • Narayan S, Roy D. (2003). Role of APC and DNA mismatch repair genes in the development of colorectal cancers. Mol Cancer 2: 41.
    • (2003) Mol Cancer , vol.2 , pp. 41
    • Narayan, S.1    Roy, D.2
  • 52
    • 23144445446 scopus 로고    scopus 로고
    • Functional coordination of intraflagellar transport motors
    • DOI 10.1038/nature03818
    • Ou G, Blacque OE, Snow JJ, Leroux MR, Scholey JM. (2005). Functional coordination of intraflagellar transport motors. Nature 436: 583-587. (Pubitemid 41112934)
    • (2005) Nature , vol.436 , Issue.7050 , pp. 583-587
    • Ou, G.1    Blacque, O.E.2    Snow, J.J.3    Leroux, M.R.4    Scholey, J.M.5
  • 53
    • 17144377111 scopus 로고    scopus 로고
    • Cilia-generated signaling and ciliarelated disorders
    • Pan J, Wang Q, Snell WJ. (2005). Cilia-generated signaling and ciliarelated disorders. Lab Invest 85: 452-463.
    • (2005) Lab Invest , vol.85 , pp. 452-463
    • Pan, J.1    Wang, Q.2    Snell, W.J.3
  • 54
    • 0032843811 scopus 로고    scopus 로고
    • Estimates of the worldwide mortality from 25 cancers in 1990
    • DOI 10.1002/(SICI)1097-0215(19990924)83:1<18::AID-IJC5>3.0.CO;2-M
    • Pisani P, Parkin DM, Bray F, Ferlay J. (1999). Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer 83: 18-29. (Pubitemid 29409471)
    • (1999) International Journal of Cancer , vol.83 , Issue.1 , pp. 18-29
    • Pisani, P.1    Parkin, D.M.2    Bray, F.3    Ferlay, J.4
  • 55
    • 33947322678 scopus 로고    scopus 로고
    • The intraflagellar transport component IFT88/polaris is a centrosomal protein regulating G1-S transition in non-ciliated cells
    • DOI 10.1242/jcs.03366
    • Robert A, Margall-Ducos G, Guidotti JE, Brégerie O, Celati C, Bréchot C et al. (2007). The intraflagellar transport component IFT88/polaris is a centrosomal protein regulating G1-S transition in non-ciliated cells. J Cell Sci 120: 628-637. (Pubitemid 46437897)
    • (2007) Journal of Cell Science , vol.120 , Issue.4 , pp. 628-637
    • Robert, A.1    Margall-Ducos, G.2    Guidotti, J.-E.3    Bregerie, O.4    Celati, C.5    Brechot, C.6    Desdouets, C.7
  • 56
    • 0029664368 scopus 로고    scopus 로고
    • Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly
    • Rubinfeld B, Albert I, Porfiri E, Fiol C, Munemitsu S, Polakis P. (1996). Binding of GSK3b to the APC-β-catenin complex and regulation of complex assembly. Science 272: 1023-1026. (Pubitemid 26259322)
    • (1996) Science , vol.272 , Issue.5264 , pp. 1023-1026
    • Rubinfeld, B.1    Albert, I.2    Porfiri, E.3    Fiol, C.4    Munemitsu, S.5    Polakis, P.6
  • 57
    • 0030871048 scopus 로고    scopus 로고
    • Loss of β-catenin regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene
    • Rubinfeld B, Albret I, Porfiri E, Munemitsu S, Polakis P. (1997). Loss of beta-catein regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene. Cancer Res 57: 4624-4630. (Pubitemid 27441070)
    • (1997) Cancer Research , vol.57 , Issue.20 , pp. 4624-4630
    • Rubinfeld, B.1    Albert, I.2    Porfiri, E.3    Munemitsu, S.4    Polakis, P.5
  • 59
    • 0035921733 scopus 로고    scopus 로고
    • Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the β-catenin gene
    • DOI 10.1038/sj.onc.1204825
    • Saadi-Kheddouci S, Berrebi D, Romagnolo B, Cluzeaud F, Peuchmaur M, Kahn A et al. (2001). Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the β-catenin gene. Oncogene 20: 5972-5981. (Pubitemid 32955039)
    • (2001) Oncogene , vol.20 , Issue.42 , pp. 5972-5981
    • Saadi-Kheddouci, S.1    Berrebi, D.2    Romagnolo, B.3    Cluzeaud, F.4    Peuchmaur, M.5    Kahn, A.6    Vandewalle, A.7    Perret, C.8
  • 62
    • 18444367105 scopus 로고    scopus 로고
    • Intraflagellar transport and the flagellar tip complex
    • Sloboda RD. (2004). Intraflagellar transport and the flagellar tip complex. J Cell Biochem 94: 266-272.
    • (2004) J Cell Biochem , vol.94 , pp. 266-272
    • Sloboda, R.D.1
  • 65
    • 18744406718 scopus 로고    scopus 로고
    • FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination
    • DOI 10.1038/nature03494
    • Tanaka Y, Okada Y, Hirokawa N. (2005). FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination. Nature 435: 172-177. (Pubitemid 40685936)
    • (2005) Nature , vol.435 , Issue.7039 , pp. 172-177
    • Tanaka, Y.1    Okada, Y.2    Hirokawa, N.3
  • 67
    • 0034658368 scopus 로고    scopus 로고
    • EB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stability
    • DOI 10.1083/jcb.149.4.761
    • Tirnauer JS, Bierer BE. (2000). EB1 proteins regulate microtubule dynamics cell polarity and chromosome stability. J Cell Biol 149: 761-766. (Pubitemid 30327228)
    • (2000) Journal of Cell Biology , vol.149 , Issue.4 , pp. 761-766
    • Tirnauer, J.S.1    Bierer, B.E.2
  • 68
    • 0347357836 scopus 로고    scopus 로고
    • Polycystic Kidney Disease
    • DOI 10.1056/NEJMra022161
    • Wilson PD. (2004). Polycystic kidney disease. N Engl J Med 350: 151-164. (Pubitemid 38056226)
    • (2004) New England Journal of Medicine , vol.350 , Issue.2 , pp. 151-164
    • Wilson, P.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.