Fanconi anemia D2 protein is an apoptotic target mediated by caspases

Journal of Cellular Biochemistry

Volumn 112, Issue 9, 2011, Pages 2383-2391

  Park, Su Jung ^a   Beck, Brian D ^a   Saadatzadeh, M Reza ^a   Haneline, Laura S ^a   Clapp, D Wade ^a   Lee, Suk Hee ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Caspase; Cisplatin; Dna damage; DNA repair; Fanconi anemia; Mitomycin C

Indexed keywords

BRCA1 PROTEIN; CASPASE; CASPASE INHIBITOR; CISPLATIN; FANCONI ANEMIA GROUP D2 PROTEIN; MITOMYCIN C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEASOME INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CELL DEATH; CELL KILLING; CELL STIMULATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TARGETING; UBIQUITINATION; ULTRAVIOLET RADIATION;

APOPTOSIS; CASPASES; CISPLATIN; CROSS-LINKING REAGENTS; DNA DAMAGE; FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN; HELA CELLS; HUMANS; MITOMYCIN; PROTEASOME ENDOPEPTIDASE COMPLEX; TUMOR NECROSIS FACTOR-ALPHA; UBIQUITINATED PROTEINS;

EID: 84860404194     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23161     Document Type: Article

References (37)

1. Blagosklonny MV, An WG, Melillo G, Nguyen P, Trepel JB, Neckers LM,. 1999. Regulation of BRCA1 by protein degradation. Oncogene 18: 6460-6468.
2. Bogliolo M, Lyakhovich A, Callen E, Castella M, Cappelli E, Ramirez MJ, Creus A, Marcos R, Kalb R, Neveling K, Schindler D, Surralles J,. 2007. Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability. EMBO J 26: 1340-1351. (Pubitemid 46398698)
3. Boulon S, Westman BJ, Hutten S, Boisvert FM, Lamond AI,. 2010. The nucleolus under stress. Mol Cell 40: 216-227.
4. Brodeur I, Goulet I, Tremblay CS, Charbonneau C, Delisle MC, Godin C, Huard C, Khandjian EW, Buchwald M, Levesque G, Carreau M,. 2004. Regulation of the Fanconi anemia group C protein through proteolytic modification. J Biol Chem 279: 4713-4720. (Pubitemid 38199065)
5. Casciola-Rosen LA, Anhalt GJ, Rosen A,. 1995. DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis. J Exp Med 182: 1625-1634.
6. Chou DM, Adamson B, Dephoure NE, Tan X, Nottke AC, Hurov KE, Gygi SP, Colaiacovo MP, Elledge SJ,. 2010. A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive Polycomb and NuRD complexes to sites of DNA damage. Proc Natl Acad Sci USA 107: 18475-18480.
7. Das S, Boswell SA, Aaronson SA, Lee SW,. 2008. P53 promoter selection: Choosing between life and death. Cell Cycle 7: 154-157. (Pubitemid 351366513)
8. Del Bello B, Valentini MA, Comporti M, Maellaro E,. 2003. Cisplatin-induced apoptosis in melanoma cells: role of caspase-3 and caspase-7 in Apaf-1 proteolytic cleavage and in execution of the degradative phases. Ann N Y Acad Sci 1010: 200-204. (Pubitemid 38264975)
9. Fan Z, Beresford PJ, Zhang D, Xu Z, Novina CD, Yoshida A, Pommier Y, Lieberman J,. 2003. Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A. Nat Immunol 4: 145-153. (Pubitemid 36193016)
10. Freie B, Li X, Ciccone SL, Nawa K, Cooper S, Vogelweid C, Schantz L, Haneline LS, Orazi A, Broxmeyer HE, Lee SH, Clapp DW,. 2003. Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis. Blood 102: 4146-4152. (Pubitemid 37487001)
11. Fuentes-Prior P, Salvesen GS,. 2004. The protein structures that shape caspase activity, specificity, activation and inhibition. Biochem J 384: 201-232. (Pubitemid 39656233)
12. Garcia-Higuera I, Taniguchi T, Ganesan S, Meyn MS, Timmers C, Hejna J, Grompe M, D'Andrea AD,. 2001. Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol Cell 7: 249-262. (Pubitemid 32206493)
13. Haglund K, Sigismund S, Polo S, Szymkiewicz I, Di Fiore PP, Dikic I,. 2003. Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation. Nat Cell Biol 5: 461-466. (Pubitemid 36592270)
14. Jackson SP, Jeggo PA,. 1995. DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK. Trends Biochem Sci 20: 412-415.
15. Kennedy RD, D'Andrea AD,. 2005. The Fanconi anemia/BRCA pathway: New faces in the crowd. Genes Dev 19: 2925-2940. (Pubitemid 41798109)
16. Lazebnik YA, Kaufmann SH, Desnoyers S, Poirier GG, Earnshaw WC,. 1994. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371: 346-347. (Pubitemid 24300618)
17. Liu T, Ghosal G, Yuan J, Chen J, Huang J,. 2010. FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair. Science 329: 693-696.
18. Ljungman M, Lane DP,. 2004. Transcription-Guarding the genome by sensing DNA damage. Nat Rev Cancer 4: 727-737. (Pubitemid 39215071)
19. Meetei AR, de Winter JP, Medhurst AL, Wallisch M, Waisfisz Q, van de Vrugt HJ, Oostra AB, Yan Z, Ling C, Bishop CE, Hoatlin ME, Joenje H, Wang W,. 2003. A novel ubiquitin ligase is deficient in Fanconi anemia. Nat Genet 35: 165-170. (Pubitemid 37187635)
20. Moldovan GL, D'Andrea AD,. 2009. How the Fanconi anemia pathway guards the genome. Annu Rev Genet 43: 223-249.
21. Nakanishi K, Taniguchi T, Ranganathan V, New HV, Moreau LA, Stotsky M, Mathew CG, Kastan MB, Weaver DT, D'Andrea AD,. 2002. Interaction of FANCD2 and NBS1 in the DNA damage response. Nat Cell Biol 4: 913-920. (Pubitemid 35469420)
22. Park SJ, Oh EJ, Yoo MA, Lee SH,. 2001. Involvement of DNA-dependent protein kinase in regulation of stress-induced JNK activation. DNA Cell Biol 20: 637-645.
23. Park SJ, Ciccone SL, Beck BD, Hwang B, Freie B, Clapp DW, Lee SH,. 2004. Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins. J Biol Chem 279: 30053-30059. (Pubitemid 38937926)
24. Rheaume E, Cohen LY, Uhlmann F, Lazure C, Alam A, Hurwitz J, Sekaly RP, Denis F,. 1997. The large subunit of replication factor C is a substrate for caspase-3 in vitro and is cleaved by a caspase-3-like protease during Fas-mediated apoptosis. EMBO J 16: 6346-6354. (Pubitemid 27483261)
25. Schultz N, Lopez E, Saleh-Gohari N, Helleday T,. 2003. Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination. Nucleic Acids Res 31: 4959-4964. (Pubitemid 37441861)
26. Song Q, Lees-Miller SP, Kumar S, Zhang Z, Chan DW, Smith GC, Jackson SP, Alnemri ES, Litwack G, Khanna KK, Lavin MF,. 1996. DNA-dependent protein kinase catalytic subunit: A target for an ICE-like protease in apoptosis. EMBO J 15: 3238-3246. (Pubitemid 26231929)
27. Susse S, Scholz CJ, Burkle A, Wiesmuller L,. 2004. Poly(ADP-ribose) polymerase (PARP-1) and p53 independently function in regulating double-strand break repair in primate cells. Nucleic Acids Res 32: 669-680. (Pubitemid 38263058)
28. Taniguchi T, Garcia-Higuera I, Andreassen PR, Gregory RC, Grompe M, D'Andrea AD,. 2002. S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. Blood 100: 2414-2420.
29. Toyozumi Y, Arima N, Izumaru S, Kato S, Morimatsu M, Nakashima T,. 2004. Loss of caspase-8 activation pathway is a possible mechanism for CDDP resistance in human laryngeal squamous cell carcinoma, HEp-2 cells. Int J Oncol 25: 721-728.
30. Vandenberg CJ, Gergely F, Ong CY, Pace P, Mallery DL, Hiom K, Patel KJ,. 2003. BRCA1-independent ubiquitination of FANCD2. Mol Cell 12: 247-254. (Pubitemid 36945048)
31. Vaz F, Hanenberg H, Schuster B, Barker K, Wiek C, Erven V, Neveling K, Endt D, Kesterton I, Autore F, Fraternali F, Freund M, Hartmann L, Grimwade D, Roberts RG, Schaal H, Mohammed S, Rahman N, Schindler D, Mathew CG,. 2010. Mutation of the RAD51C gene in a Fanconi anemia-like disorder. Nat Genet 42: 406-409.
32. 2-terminal kinase inhibitor treatment, prevent cisplatin-induced hearing loss. Cancer Res 64: 9217-9224. (Pubitemid 39665538)
33. Wang X, Andreassen PR, D'Andrea AD,. 2004b. Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. Mol Cell Biol 24: 5850-5862. (Pubitemid 38787970)
34. Wyllie AH,. 1980. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555-556. (Pubitemid 10070336)
35. Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz HR,. 1993. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell 75: 641-652. (Pubitemid 23346363)
36. Yuan F, El Hokayem J, Zhou W, Zhang Y,. 2009. FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures. J Biol Chem 284: 24443-24452.
37. Zhan Q, Jin S, Ng B, Plisket J, Shangary S, Rathi A, Brown KD, Baskaran R,. 2002. Caspase-3 mediated cleavage of BRCA1 during UV-induced apoptosis. Oncogene 21: 5335-5345. (Pubitemid 34948144)