The large subunit of replication factor C is a substrate for caspase-3 in vitro and is cleaved by a caspase-3-like protease during fas-mediated apoptosis

EMBO Journal

Volumn 16, Issue 21, 1997, Pages 6346-6354

  Rhéaume, Eric ^a   Cohen, Luchino Y ^a   Uhlmann, Frank ^b   Lazure, Claude ^a   Alam, Antoine ^a   Hurwitz, Jerard ^b   Sékaly, Rafick Pierre ^a,c,d   Denis, François ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c MCGILL UNIVERSITY   (Canada)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Apoptosis; CPP32; PARP; Programmed cell death; RF C

Indexed keywords

CASPASE; CYSTEINE PROTEINASE; DNA FRAGMENT; DNA POLYMERASE; FAS ANTIGEN; MULTIENZYME COMPLEX; PEPTIDE HYDROLASE; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CELL CYCLE; CONTROLLED STUDY; DNA REPLICATION; ENZYME SUBSTRATE; ENZYME SUBUNIT; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANTIGENS, CD95; APOPTOSIS; CASPASE 3; CASPASES; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DNA REPLICATION; DNA-BINDING PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; LEUKEMIA, T-CELL, ACUTE; LYMPHOCYTES; NEOPLASM PROTEINS; OLIGOPEPTIDES; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT FUSION PROTEINS; REPLICATION PROTEIN C; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SUBSTRATE SPECIFICITY; TUMOR CELLS, CULTURED;

EUKARYOTA;

EID: 0343306746     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.21.6346     Document Type: Article

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