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Volumn 112, Issue 9, 2011, Pages 2222-2229

The role of Lrp5/6 in cardiac valve disease: LDL-density-pressure theory

Author keywords

Lipids; Lrp5; Osteoblastogenesis; Wnt

Indexed keywords

LIPID; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; WNT PROTEIN;

EID: 84860390043     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23182     Document Type: Article
Times cited : (35)

References (68)
  • 2
    • 75049083319 scopus 로고    scopus 로고
    • Wnt signaling in heart valve development and osteogenic gene induction
    • Alfieri CM, Cheek J, Chakraborty S, Yutzey KE,. 2010. Wnt signaling in heart valve development and osteogenic gene induction. Dev Biol 338: 127-135.
    • (2010) Dev Biol , vol.338 , pp. 127-135
    • Alfieri, C.M.1    Cheek, J.2    Chakraborty, S.3    Yutzey, K.E.4
  • 3
    • 0023238604 scopus 로고
    • Correlation of serum lipids, calcium, and phosphorus, diabetes mellitus and history of systemic hypertension with presence or absence of calcified or thickened aortic cusps or root in elderly patients
    • DOI 10.1016/0002-9149(87)91144-1
    • Aronow WS, Schwartz KS, Koenigsberg M,. 1987. Correlation of serum lipids, calcium, and phosphorus, diabetes mellitus and history of systemic hypertension with presence or absence of calcified or thickened aortic cusps or root in elderly patients. Am J Cardiol 59: 998-999. (Pubitemid 17074253)
    • (1987) American Journal of Cardiology , vol.59 , Issue.9 , pp. 998-999
    • Aronow, W.S.1    Schwartz, K.S.2    Koenigsberg, M.3
  • 4
    • 0035421721 scopus 로고    scopus 로고
    • Association of mitral annular calcium with symptomatic peripheral arterial disease in older persons
    • DOI 10.1016/S0002-9149(01)01657-5, PII S0002914901016575
    • Aronow WS, Ahn C, Kronzon I,. 2001a. Association of mitral annular calcium with symptomatic peripheral arterial disease in older persons. Am J Cardiol 88: 333-334. (Pubitemid 32721972)
    • (2001) American Journal of Cardiology , vol.88 , Issue.3 , pp. 333-334
    • Aronow, W.S.1    Ahn, C.2    Kronzon, I.3
  • 5
    • 0035885130 scopus 로고    scopus 로고
    • Association of coronary risk factors and use of statins with progression of mild valvular aortic stenosis in older persons
    • DOI 10.1016/S0002-9149(01)01821-5, PII S0002914901018215
    • Aronow WS, Ahn C, Kronzon I, Goldman ME,. 2001b. Association of coronary risk factors and use of statins with progression of mild valvular aortic stenosis in older persons. Am J Cardiol 88: 693-695. (Pubitemid 32831111)
    • (2001) American Journal of Cardiology , vol.88 , Issue.6 , pp. 693-695
    • Aronow, W.S.1    Ahn, C.2    Kronzon, I.3    Goldman, M.E.4
  • 8
    • 0030814909 scopus 로고    scopus 로고
    • Cardiac valve calcification: Characteristics of patients with calcification of the mitral annulus or aortic valve
    • Boon A, Cheriex E, Lodder J, Kessels F,. 1997. Cardiac valve calcification: Characteristics of patients with calcification of the mitral annulus or aortic valve. Heart 78: 472-474. (Pubitemid 27515107)
    • (1997) Heart , vol.78 , Issue.5 , pp. 472-474
    • Boon, A.1    Cheriex, E.2    Lodder, J.3    Kessels, F.4
  • 13
    • 0035884862 scopus 로고    scopus 로고
    • Case-controlled study to assess risk factors for aortic stenosis in congenitally bicuspid aortic valve
    • DOI 10.1016/S0002-9149(01)01820-3, PII S0002914901018203
    • Chan KL, Ghani M, Woodend K, Burwash IG,. 2001. Case-controlled study to assess risk factors for aortic stenosis in congenitally bicuspid aortic valve. Am J Cardiol 88: 690-693. (Pubitemid 32831110)
    • (2001) American Journal of Cardiology , vol.88 , Issue.6 , pp. 690-693
    • Chan, K.-L.1    Ghani, M.2    Woodend, K.3    Burwash, I.G.4
  • 14
    • 0035158955 scopus 로고    scopus 로고
    • Association between calcific aortic stenosis and hypercholesterolemia: Is there a need for a randomized controlled trial of cholesterol-lowering therapy?
    • Chui MC, Newby DE, Panarelli M, Bloomfield P, Boon NA,. 2001. Association between calcific aortic stenosis and hypercholesterolemia: Is there a need for a randomized controlled trial of cholesterol-lowering therapy? Clin Cardiol 24: 52-55. (Pubitemid 32044545)
    • (2001) Clinical Cardiology , vol.24 , Issue.1 , pp. 52-55
    • Chui, M.C.K.1    Newby, D.E.2    Panarelli, M.3    Bloomfield, P.4    Boon, N.A.5
  • 15
    • 0021265624 scopus 로고
    • Diabetes and hypercholesterolemia among patients with calcific aortic stenosis
    • Deutscher S, Rockette HE, Krishnaswami V,. 1984. Diabetes and hypercholesterolemia among patients with calcific aortic stenosis. J Chronic Dis 37: 407-415. (Pubitemid 14134891)
    • (1984) Journal of Chronic Diseases , vol.37 , Issue.5 , pp. 407-415
    • Deutscher, S.1    Rockette, H.E.2    Krishnaswami, V.3
  • 19
    • 77955155919 scopus 로고    scopus 로고
    • The multiple phases and faces of wnt signaling during cardiac differentiation and development
    • Gessert S, Kuhl M,. The multiple phases and faces of wnt signaling during cardiac differentiation and development. Circ Res 107: 186-199.
    • Circ Res , vol.107 , pp. 186-199
    • Gessert, S.1    Kuhl, M.2
  • 21
    • 3142710221 scopus 로고    scopus 로고
    • Glycosaminoglycans and proteoglycans in normal mitral valve leaflets and chordae: Association with regions of tensile and compressive loading
    • DOI 10.1093/glycob/cwh076
    • Grande-Allen KJ, Calabro A, Gupta V, Wight TN, Hascall VC, Vesely I,. 2004. Glycosaminoglycans and proteoglycans in normal mitral valve leaflets and chordae: Association with regions of tensile and compressive loading. Glycobiology 14: 621-633. (Pubitemid 38923644)
    • (2004) Glycobiology , vol.14 , Issue.7 , pp. 621-633
    • Grande-Allen, K.J.1    Clabro, A.2    Gupta, V.3    Wight, T.N.4    Hascall, V.C.5    Vesely, I.6
  • 23
    • 38349026604 scopus 로고    scopus 로고
    • Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling
    • Hassler C, Cruciat CM, Huang YL, Kuriyama S, Mayor R, Niehrs C,. 2007. Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling. Development 134: 4255-4263.
    • (2007) Development , vol.134 , pp. 4255-4263
    • Hassler, C.1    Cruciat, C.M.2    Huang, Y.L.3    Kuriyama, S.4    Mayor, R.5    Niehrs, C.6
  • 24
    • 0018876715 scopus 로고
    • Non-invasive assessment of aortic stenosis by Doppler ultrasound
    • Hatle L, Angelsen BA, Tromsdal A,. 1980. Non-invasive assessment of aortic stenosis by Doppler ultrasound. Br Heart J 43: 284-292. (Pubitemid 10096613)
    • (1980) British Heart Journal , vol.43 , Issue.3 , pp. 284-292
    • Hatle, L.1    Angelsen, B.A.2    Tromsdal, A.3
  • 26
    • 0021999869 scopus 로고
    • Case-control analysis of risk factors for presence of aortic stenosis in adults (age 50 years or older)
    • DOI 10.1016/0002-9149(85)90149-3
    • Hoagland PM, Cook EF, Flatley M, Walker C, Goldman L,. 1985. Case-control analysis of risk factors for presence of aortic stenosis in adults (age 50 years or older). Am J Cardiol 55: 744-747. (Pubitemid 15148253)
    • (1985) American Journal of Cardiology , vol.55 , Issue.6 , pp. 744-747
    • Hoagland, P.M.1    Cook, E.F.2    Flatley, M.3
  • 28
    • 0028345073 scopus 로고
    • Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice
    • Ishibashi S, Goldstein JL, Brown MS, Herz J, Burns DK,. 1994. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. J Clin Invest 93: 1885-1893. (Pubitemid 24143065)
    • (1994) Journal of Clinical Investigation , vol.93 , Issue.5 , pp. 1885-1893
    • Ishibashi, S.1    Goldstein, J.L.2    Brown, M.S.3    Herz, J.4    Burns, D.K.5
  • 30
    • 33644920994 scopus 로고    scopus 로고
    • Parameters of LRP5 from a structural and molecular perspective
    • Johnson ML, Summerfield DT,. 2005. Parameters of LRP5 from a structural and molecular perspective. Crit Rev Eukaryot Gene Expr 15: 229-242.
    • (2005) Crit Rev Eukaryot Gene Expr , vol.15 , pp. 229-242
    • Johnson, M.L.1    Summerfield, D.T.2
  • 33
    • 33947612673 scopus 로고    scopus 로고
    • Glycosylation and palmitoylation of Wnt-3a are coupled to produce an active form of Wnt-3a
    • DOI 10.1111/j.1365-2443.2007.01068.x
    • Komekado H, Yamamoto H, Chiba T, Kikuchi A,. 2007. Glycosylation and palmitoylation of Wnt-3a are coupled to produce an active form of Wnt-3a. Genes Cells 12: 521-534. (Pubitemid 46488587)
    • (2007) Genes to Cells , vol.12 , Issue.4 , pp. 521-534
    • Komekado, H.1    Yamamoto, H.2    Chiba, T.3    Kikuchi, A.4
  • 36
    • 58149343449 scopus 로고    scopus 로고
    • Mutation in EGFP domain of LDL receptor-related protein 6 impairs cellular LDL clearance
    • Liu W, Mani S, Davis NR, Sarrafzadegan N, Kavathas PB, Mani A,. 2008. Mutation in EGFP domain of LDL receptor-related protein 6 impairs cellular LDL clearance. Circ Res 103: 1280-1288.
    • (2008) Circ Res , vol.103 , pp. 1280-1288
    • Liu, W.1    Mani, S.2    Davis, N.R.3    Sarrafzadegan, N.4    Kavathas, P.B.5    Mani, A.6
  • 40
    • 0026320323 scopus 로고
    • Development and progression of aortic valve stenosis: Atherosclerosis risk factors-A causal relationship? A clinical morphologic study
    • Mohler ER, Sheridan MJ, Nichols R, Harvey WP, Waller BF,. 1991. Development and progression of aortic valve stenosis: Atherosclerosis risk factors-A causal relationship? A clinical morphologic study. Clin Cardiol 14: 995-999.
    • (1991) Clin Cardiol , vol.14 , pp. 995-999
    • Mohler, E.R.1    Sheridan, M.J.2    Nichols, R.3    Harvey, W.P.4    Waller, B.F.5
  • 45
    • 0033565955 scopus 로고    scopus 로고
    • Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly
    • DOI 10.1056/NEJM199907153410302
    • Otto CM, Lind BK, Kitzman DW, Gersh BJ, Siscovick DS,. 1999. Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly [comment]. N Engl J Med 341: 142-147. (Pubitemid 29325741)
    • (1999) New England Journal of Medicine , vol.341 , Issue.3 , pp. 142-147
    • Otto, C.M.1    Lind, B.K.2    Kitzman, D.W.3    Gersh, B.J.4    Siscovick, D.S.5
  • 46
    • 0034738139 scopus 로고    scopus 로고
    • New insights into the progression of aortic stenosis: Implications for secondary prevention
    • Palta S, Pai AM, Gill KS, Pai RG,. 2000. New insights into the progression of aortic stenosis: Implications for secondary prevention. Circulation 101: 2497-2502. (Pubitemid 30366254)
    • (2000) Circulation , vol.101 , Issue.21 , pp. 2497-2502
    • Palta, S.1    Pai, A.M.2    Gill, K.S.3    Pai, R.G.4
  • 47
    • 0037218968 scopus 로고    scopus 로고
    • Relation between cardiovascular risk factors and nonrheumatic severe calcific aortic stenosis among patients with a three-cuspid aortic valve
    • DOI 10.1016/S0002-9149(02)03010-2, PII S0002914902030102
    • Peltier M, Trojette F, Sarano ME, Grigioni F, Slama MA, Tribouilloy CM,. 2003. Relation between cardiovascular risk factors and nonrheumatic severe calcific aortic stenosis among patients with a three-cuspid aortic valve. Am J Cardiol 91: 97-99. (Pubitemid 36050783)
    • (2003) American Journal of Cardiology , vol.91 , Issue.1 , pp. 97-99
    • Peltier, M.1    Trojette, F.2    Sarano, M.E.3    Grigioni, F.4    Slama, M.A.5    Tribouilloy, C.M.6
  • 48
    • 0034727078 scopus 로고    scopus 로고
    • An LDL-receptor-related protein mediates Wnt signalling in mice
    • Pinson KI, Brennan J, Monkley S, Avery BJ, Skarnes WC,. 2000. An LDL-receptor-related protein mediates Wnt signalling in mice. Nature 407: 535-538.
    • (2000) Nature , vol.407 , pp. 535-538
    • Pinson, K.I.1    Brennan, J.2    Monkley, S.3    Avery, B.J.4    Skarnes, W.C.5
  • 49
    • 0035899912 scopus 로고    scopus 로고
    • Progression of aortic valve calcification: Association with coronary atherosclerosis and cardiovascular risk factors
    • Pohle K, Maffert R, Ropers D, Moshage W, Stilianakis N, Daniel WG, Achenbach S,. 2001. Progression of aortic valve calcification: Association with coronary atherosclerosis and cardiovascular risk factors. Circulation 104: 1927-1932. (Pubitemid 32983236)
    • (2001) Circulation , vol.104 , Issue.16 , pp. 1927-1932
    • Pohle, K.1    Maffert, R.2    Ropers, D.3    Moshage, W.4    Stilianakis, N.5    Daniel, W.G.6    Achenbach, S.7
  • 55
    • 24644510707 scopus 로고    scopus 로고
    • Atorvastatin inhibits hypercholesterolemia-induced calcification in the aortic valves via the Lrp5 receptor pathway
    • DOI 10.1161/01.CIRCULATIONAHA.104.524306
    • Rajamannan NM, Subramaniam M, Caira F, Stock SR, Spelsberg TC,. 2005a. Atorvastatin inhibits hypercholesterolemia-induced calcification in the aortic valves via the Lrp5 receptor pathway. Circulation 112: I229-I234. (Pubitemid 41266679)
    • (2005) Circulation , vol.112 , Issue.9 SUPPL.
    • Rajamannan, N.M.1    Subramaniam, M.2    Caira, F.3    Stock, S.R.4    Spelsberg, T.C.5
  • 60
  • 62
    • 5044228112 scopus 로고    scopus 로고
    • Wnt signaling in osteoblasts and bone diseases
    • DOI 10.1016/j.gene.2004.06.044, PII S0378111904003853
    • Westendorf JJ, Kahler RA, Schroeder TM,. 2004. Wnt signaling in osteoblasts and bone diseases. Gene 341: 19-39. (Pubitemid 39335880)
    • (2004) Gene , vol.341 , Issue.1-2 , pp. 19-39
    • Westendorf, J.J.1    Kahler, R.A.2    Schroeder, T.M.3
  • 63
    • 0023121507 scopus 로고
    • Quantitative structural analysis of collagen in chordae tendineae and its relation to floppy mitral valves and proteoglycan infiltration
    • Whittaker P, Boughner DR, Perkins DG, Canham PB,. 1987. Quantitative structural analysis of collagen in chordae tendineae and its relation to floppy mitral valves and proteoglycan infiltration. Br Heart J 57: 264-269. (Pubitemid 17039354)
    • (1987) British Heart Journal , vol.57 , Issue.3 , pp. 264-269
    • Whittaker, P.1    Boughner, D.R.2    Perkins, D.G.3    Canham, P.B.4
  • 64
    • 58649087137 scopus 로고    scopus 로고
    • Where Wnts went: The exploding field of Lrp5 and Lrp6 signaling in bone
    • Williams BO, Insogna KL,. 2009. Where Wnts went: The exploding field of Lrp5 and Lrp6 signaling in bone. J Bone Miner Res 24: 171-178.
    • (2009) J Bone Miner Res , vol.24 , pp. 171-178
    • Williams, B.O.1    Insogna, K.L.2
  • 65
    • 0030734286 scopus 로고    scopus 로고
    • A case-control investigation of the relation between hyperlipidaemia and calcific aortic valve stenosis
    • Wilmshurst PT, Stevenson RN, Griffiths H, Lord JR,. 1997. A case-control investigation of the relation between hyperlipidaemia and calcific aortic valve stenosis. Heart 78: 475-479. (Pubitemid 27515108)
    • (1997) Heart , vol.78 , Issue.5 , pp. 475-479
    • Wilmshurst, P.T.1    Stevenson, R.N.2    Griffiths, H.3    Lord, J.R.4
  • 67
    • 33746482870 scopus 로고    scopus 로고
    • Caveolin Is Necessary for Wnt-3a-Dependent Internalization of LRP6 and Accumulation of β-Catenin
    • DOI 10.1016/j.devcel.2006.07.003, PII S1534580706003042
    • Yamamoto H, Komekado H, Kikuchi A,. 2006. Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin. Dev Cell 11: 213-223. (Pubitemid 44138502)
    • (2006) Developmental Cell , vol.11 , Issue.2 , pp. 213-223
    • Yamamoto, H.1    Komekado, H.2    Kikuchi, A.3


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