IL-2 simultaneously expands Foxp3 + T regulatory and T effector cells and confers resistance to severe tuberculosis (TB): Implicative treg-T effector cooperation in immunity to TB

Journal of Immunology

Volumn 188, Issue 9, 2012, Pages 4278-4288

  Chen, Crystal Y ^a   Huang, Dan ^a   Yao, Shuyu ^a   Halliday, Lisa ^b   Zeng, Gucheng ^a   Wang, Richard C ^a   Chen, Zheng W ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; PERFORIN; RECOMBINANT INTERLEUKIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL IMMUNITY; BACTERIAL LOAD; BIOACCUMULATION; CD4+ CD25+ FOXP3+ T REGULATORY LYMPHOCYTE; CD4+ T EFFECTOR CELL; CD8+ CD25+ FOXP3+ T LYMPHOCYTE; CD8+ T EFFECTOR CELL; CELL EXPANSION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG INTERMITTENT THERAPY; EFFECTOR CELL; IN VIVO STUDY; INFECTION RESISTANCE; MACACA; MULTIPLE CYCLE TREATMENT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION; TUBERCULOSIS;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; FORKHEAD TRANSCRIPTION FACTORS; IMMUNITY, CELLULAR; INTERFERON-GAMMA; INTERLEUKIN-2; MACACA FASCICULARIS; MYCOBACTERIUM TUBERCULOSIS; PERFORIN; T-LYMPHOCYTES, REGULATORY; TUBERCULOSIS, PULMONARY;

EID: 84860342096     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101291     Document Type: Article

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