Protective role of cyclooxygenase (COX)-2 in experimental lung injury: Evidence of a lipoxin A 4-mediated effect

Journal of Surgical Research

Volumn 175, Issue 1, 2012, Pages 176-184

  Scully, Michael ^a   Gang, Chen ^a   Condron, Claire ^a   Bouchier Hayes, David ^a   Cunningham, Anthony J ^a  

^a BEAUMONT HOSPITAL   (Ireland)

Author keywords

cyclooxygenase; iloprost; ischemic reperfusion; lipoxin; lung

Indexed keywords

4 [5 (4 CHLOROPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; 6 OXOPROSTAGLANDIN F1 ALPHA; ACETYLSALICYLIC ACID; CYCLOOXYGENASE 2; ILOPROST; LIPOXIN A; MYELOPEROXIDASE; PROSTAGLANDIN E2; THROMBOXANE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CLAMPING; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; ENZYME INHIBITION; IMMUNOHISTOCHEMISTRY; INHIBITION KINETICS; LUNG INJURY; LUNG LAVAGE; MALE; NEUTROPHIL COUNT; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANIMALS; ASPIRIN; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DISEASE MODELS, ANIMAL; ILOPROST; LIPOXINS; LUNG; LUNG INJURY; MALE; PROTECTIVE AGENTS; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SULFONAMIDES;

EID: 84860317574     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2011.02.020     Document Type: Article

References (59)

1. T. Karamura, R. Wakusawa, and K. Okada Elevation of cytokines during open heart surgery with cardiopulmonary bypass: Participation of interleukin 8 and 6 in reperfusion injury Can J Anaesth 40 1993 1016
2. B. Krishnadasan, B.V. Naidu, and K. Byrne The role of proinflammatory cytokines in lung ischemia/reperfusion injury J Thorac Cardiovasc Surg 125 2003 261
3. G.M. Rocker Ischemia/reperfusion, inflammatory responses and acute lung injury Thorax 52 1997 841
4. P.G.H.M. Raijmakers, A.B.J. Groeneveld, and J.A. Rauwerda Transient increase in interleukin-8 and pulmonary microvascular permeability following aortic surgery Am J Respir Crit Care Med 151 1995 698
5. C. Adembri, E. Kastamoniti, and I. Bertolozzi Pulmonary injury follows systemic inflammatory reaction in infra-renal aortic surgery Crit Care Med 32 2004 1170
6. I.S. Paterson, J.H. Klausner, and G. Goldman Pulmonary edema after aneurysm surgery is modified by mannitol Ann Surg 210 1989 796
7. C. Jayr, M.A. Matthay, and J. Goldstone Preoperative and intraoperative factors associated with prolonged mechanical ventilation. A study in patients following major abdominal vascular surgery Chest 103 1993 1231
8. N.P. Dowd, M. Scully, and S.R. Adderley Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo J Clin Invest 108 2001 5855
9. T.G. Neilan, G.A. Doherty, and G. Chen Disruption of COX-2 modulates gene expression and the cardiac injury response to doxorubicin Am J Physiol Heart Circ Physiol 291 2006 H532
10. T.G. Neilan, D.S. Jassal, and M.F. Scully Iloprost attenuates doxorubicin-induced cardiac injury in a murine model without compromising tumour suppression Eur Heart J 27 2006 1251
11. K. Fukunaga, P. Kohli, and C. Bonnans Cyclooxygenase 2 plays a pivotal role in the resolution of acute lung injury J Immunol 174 2005 5033
12. R.J. Hodges, R.G. Jenkins, and C.P. Wheeler Jones Severity of lung injury in cyclooxygenase-2 deficient mice is dependent on reduced prostaglandin E(2) production Am J Path 165 2004 1663
13. N. Maricic, K. Ehrlich, and B. Gretzer Selective cyclooxygenase-2 inhibitors aggravate ischaemia-reperfusion injury in the rat stomach Br J Pharmacol 128 1999 1659
14. N.M. Davies, K.A. Sharkey, and S. Asfaha Aspirin causes rapid up-regulation of cyclo-oxygenase-2 expression in the stomach of rats Aliment Pharmacol Ther 11 1997 1101
15. C. Bonnans, K. Fukunanga, and M.A. Levy Lipoxin A(4) regulates bronchial epithelial cell responses to acid injury Am J Patho 168 2006 1064
16. C.N. Serhan, N. Chiang, and T.E. Van Dyke Resolving inflammation: Dual anti-inflammatory and pro-resolution lipid mediators Nat Rev Immunol 8 2008 349
17. U. Ramstedt, C.N. Serhan, and K.C. Nicolaou Lipoxin A-induced inhibition of human natural killer cell cytotoxicity; studies on stereospecificity of inhibition and modes of action J Immunol 138 1987 266
18. B. McMahon, and C. Godson Lipoxins: Endogenous regulators of inflammation Am J Physiol 286 2004 F189
19. C.N. Serhan Special issue on lipoxins and aspirin-triggered lipoxins Prostaglandins Leukot Essent Fatty Acids 73 2005 139
20. 4 by pioglitazone and atorvastatin in the rat Circulation 114 2006 929
21. P.H. McCormick, G. Chen, and S. Tierney Clinically relevant thermal preconditioning attenuates ischemia-reperfusion injury J Surg Res 109 2003 24
22. M. Joyce, C.J. Kelly, and G. Chen Pravastatin attenuates lower torso ischaemia-reperfusion-induced lung injury by up-regulating constitutive endothelial nitric oxide synthase Eur J Vasc Endovasc Surg 21 2001 295
23. M. Timlin, C. Condron, and D. Toomey N-acetylcysteine attenuates lung injury in a rodent model of fracture Acta Orthop Scand 75 2004 61
24. P.A. Lapchak, D.M. Araujo, and D. Song Neutroprotection by the selective cyclooxygenase- 2 inhibitor SC236 results in improvements in behavioral deficits induced by reversible spinal cord ischaemia Stroke 32 2001 1220
25. M.B. Grisham, J.N. Benoit, and D.N. Granger Assessment of leukocyte involvement during ischemia and reperfusion of intestine L. Packer, A.N. Glazer, Methods in Enzymology, Vol. 186 1990 Academic Press San Diego 729 742
26. G. Goldman, R. Welbourn, and L. Kobzik Synergism between leukotriene B4 and thromboxane A2 in mediating acid-aspiration injury Surgery 111 1992 55
27. T. Nagase, N. Uozumi, and S. Ishii Acute lung injury by sepsis and acid aspiration: A key role for cytosolic phospholipase A2 Nat Immunol 1 2000 42
28. Y. Sunose, I. Takeyoshi, and H. Tsutsumi Effect of a cyclooxygenase-2 inhibitor, FK3311, in a canine lung transplantation model Ann Thorac Surg 72 2001 1165
29. A.G. Ljungman, C.M. Grum, and G.M. Deeb Inhibition of cyclooxygenase metabolite production attenuates ischemia-reperfusion lung injury Am Rev Respir Dis 143 1991 610
30. G.R. Bernard The effects of ibuprofen on the physiology and survival of patients with sepsis N Engl J Med 336 1997 912
31. D.W. Gilroy, P.R. Colville-Nash, and D. Willis Inducible cyclooxygenase may have anti-inflammatory properties Nat Med 5 1999 698
32. J.L. Wallace, A. Bak, and W. McKnight Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: Implications for gastrointestinal toxicity Gastroenterology 115 1998 101
33. J.L. Wallace Commonality of defensive roles of COX-2 in the lung and gut Am J Pathol 168 2006 1060
34. B.K. Reuter, S. Asfaha, and A. Buret Exacerbation of inflammation- associated colonic injury in rat through inhibition of cyclooxygenase-2 J Clin Invest 98 1996 2076
35. G.Y. Park, and J.W. Christman Involvement of cyclooxygenase-2 and prostaglandins in the molecular pathogenesis of inflammatory lung diseases Am J Physiol Lung Cell Mol Physiol 290 2006 797
36. B.D. Levy, C.B. Clish, and B. Schmidt Lipid mediator class switching during acute inflammation: Signals in resolution Nat Immunol 2 2001 612
37. C. Nathan Points of control in inflammation Nature 420 2002 846
38. M.A. Matthay, and G.A. Zimmerman Acute lung injury and the acute respiratory distress syndrome: Four decades of inquiry into pathogenesis and rational management Am J Respir Cell Mol Biol 33 2005 319
39. T. Takano, C.B. Clish, and K. Gronert Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues J Clin Invest 101 1998 819
40. R. Scalia, J. Gefen, and N.A. Petasis Lipoxin A4 stable analogs inhibit leukocyte rolling and adherence in the rat mesenteric microvasculature: Role of P-selectin Proc Natl Acad Sci USA 94 1997 9967
41. A. Baltalarli, V. Ozcan, and H. Aybek Ascorbic acid (vitamin C) and iloprost attenuate the lung injury caused by ischemia/reperfusion of the lower extremities of rats Ann Vas Surg 20 2006 49
42. M. Kawashima, T. Nakamura, and S. Schneider Iloprost ameliorates post-ischemic lung reperfusion injury and maintains an appropriate pulmonary ET-1 balance J Heart Lung Transplant 22 2003 794
43. O. Koksel, A. Ozdulger, and B. Aytacoglu The influence of iloprost on acute lung injury induced by hind limb ischemia-reperfusion in rats Pul Pharm Ther 18 2005 235
44. A.A. Birukova, P. Fu, and J. Xing Rap-1 mediates protective effects of iloprost against ventilator-induced lung injury J Appl Physiol 107 2009 1900
45. Y.J. Lai, S.S. Pullamsetti, and E. Dony Role of the prostanoid EP4 receptor in iloprost-mediated vasodilatation in pulmonary hypertension Am J Respir Crit Care Med 178 2008 188
46. A. Sakamoto, J. Matsumura, and S. Mii A prostaglandin E2 receptor subtype EP4 agonist attenuates cardiovascular depression in endotoxin shock by inhibiting inflammatory cytokines and nitric oxide production Shock 22 2004 76
47. H. Wise Activation of the prostaglandin EP4-receptor subtype is highly coupled to inhibition of N-formyl-methionyl-leucyl-phenylalanine-stimulated rat neutrophil aggregation Prostaglandins Leukot Essent Fatty Acids 58 1998 77
48. K. Kabashima, T. Saji, and T. Murata The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut J Clin Invest 109 2002 883
49. J. Clària, and C.N. Serhan Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions Proc Natl Acad Sci USA 92 1995 9475
50. C. Schneider, and A.R. Barash Stereospecificity of hydrogen abstraction in the conversion of arachidonic acid to 15-R-HETE by aspirin treated cyclooxygenase-2. Implications for the alignment for the substrate in the active site J Biol Chem 275 2000 4743
51. V. Nascimento-Silva, M.A. Arruda, and C. Barja-Fidalgo Novel lipid mediator aspirin-triggered lipoxin A4 induces heme oxygenase-1 in endothelial cells Am J Physiol Cell Physiol 289 2005 C557
52. Y. Ye, Y. Lin, and S. Atar Myocardial protection by pioglitazone, atorvastatin and their combinations; mechanisms and possible interactions Am J Physiol Heart Circ Physiol 291 2006 H1158
53. M. Levi Platelets in sepsis Haematology 10 Suppl 1 2005 129
54. S. Russworm, J. Vickers, and A. Meier-Hellmann Platelet and leukocyte activation correlate with the severity of septic organ dysfunction Shock 17 2002 263
55. S.R. Steinbuhl Platelets as mediators of inflammation Hematol Oncol Clin North Am 21 2007 115
56. M.R. Looney, J.X. Nguyen, and Y. Hu Platelet depletion and aspirin treatment protect mice in a two event model of transfusion-related acute lung injury J Clin Invest 119 2009 3450
57. J. Winning, J. Neumann, and M. Kohl Antiplatelet drugs and outcome in mixed admissions to an intensive care unit Crit Care Med 38 2010 32
58. M. Romano, and C.N. Serhan Lipoxin generation by permeabilized human platelets Biochemistry 31 1992 8269
59. C.F. Franco-Penteado, I. Desouza, and S.A. Teixeira Role of nitric oxide on the increased vascular permeability and neutrophil accumulation induced by staphylococcal enterotoxin B into the mouse paw Biochem Pharmacol 61 2001 1305