Genetic variations of CYP2B6 gene were associated with plasma BPDE-Alb adducts and DNA damage levels in coke oven workers

Toxicology Letters

Volumn 211, Issue 3, 2012, Pages 232-238

  Huang, Guoxiang ^a   Guo, Huan ^a   Wu, Tangchun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

BDPE Alb adducts; CYP2B6; DNA damage; Genetic variations; PAHs

Indexed keywords

BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE; COKE; CYTOCHROME P450 2B6; POLYCYCLIC AROMATIC HYDROCARBON;

ADULT; ARTICLE; CLINICAL ARTICLE; COKING INDUSTRY; COMET ASSAY; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PLASMA; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SINGLE NUCLEOTIDE POLYMORPHISM; WORKER;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ADULT; ALBUMINS; ARYL HYDROCARBON HYDROXYLASES; CARCINOGENS; COKE; COMET ASSAY; CYTOCHROME P-450 ENZYME SYSTEM; DNA ADDUCTS; DNA DAMAGE; GENETIC VARIATION; GENOTYPE; HUMANS; MALE; METALLURGY; OCCUPATIONAL EXPOSURE; OXIDOREDUCTASES, N-DEMETHYLATING; POLYMORPHISM, SINGLE NUCLEOTIDE; SMOKING; STEEL;

EID: 84860276922     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.04.004     Document Type: Article

References (39)

1. Conney A.H. Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G.H.A. Clowes Memorial Lecture. Cancer Research 1982, 42:4875-4917.
2. Frank S., Renner T., Ruppert T., Scherer G. Determination of albumin adducts of (+)-anti-benzo[a]pyrene-diol-epoxide using high-performance liquid chromatographic column switching technique for sample preparation and gas chromatography-mass spectrometry for the final detection. Journal of Chromatography B: Biomedical Sciences and Applications 1998, 713:331-337.
3. Georgiadis P., Demopoulos N.A., Topinka J., Stephanou G., Stoikidou M., Bekyrou M., Katsouyianni K., Sram R., Autrup H., Kyrtopoulos S.A. Impact of phase I or phase II enzyme polymorphisms on lymphocyte DNA adducts in subjects exposed to urban air pollution and environmental tobacco smoke. Toxicology Letters 2004, 149:269-280.
4. Guyonnet D., Belloir C., Suschetet M., Siess M.H., Le Bon A.M. Liver subcellular fractions from rats treated by organosulfur compounds from Allium modulate mutagen activation. Mutation Research 2000, 466:17-26.
5. Haas D.W., Gebretsadik T., Mayo G., Menon U.N., Acosta E.P., Shintani A., Floyd M., Stein C.M., Wilkinson G.R. Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans. Journal of Infectious Diseases 2009, 199:872-880.
6. Hamouchene H., Arlt V.M., Giddings I., Phillips D.H. Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyrene. BMC Genomics 2011, 12:333.
7. Hoeijmakers J.H. Genome maintenance mechanisms for preventing cancer. Nature 2001, 411:366-374.
8. Hong S.P., Shin S.K., Lee E.H., Kim E.O., Ji S.I., Chung H.J., Park S.N., Yoo W., Folk W.R., Kim S.O. High-resolution human papillomavirus genotyping by MALDI-TOF mass spectrometry. Nature Protocols 2008, 3:1476-1484.
9. Islam G.A., Greibrokk T., Harvey R.G., Øvrebø S. HPLC analysis of benzo[a]pyrene albumin adducts in benzo[a]pyrene exposed rats. Detection of cis-tetrols arising from hydrolysis of adducts of anti- and sync-BPDE-III with proteins. Chemico-Biological Interactions 1999, 123:133-148.
10. John K., Divi R.L., Keshava C., Orozco C.C., Schockley M.E., Richardson D.L., Poirier M.C., Nath J., Weston A. CYP1A1 and CYP1B1 gene expression and DNA adduct formation in normal human mammary epithelial cells exposed to benzo[a]pyrene in the absence or presence of chlorophyllin. Cancer Letters 2010, 292:254-260.
11. Kato S., Bowman E.D., Harrington A.M., Blomeke B., Shields P.G. Human lung carcinogen-DNA adduct levels mediated by genetic polymorphisms in vivo. Journal of the National Cancer Institute 1995, 87:902-907.
12. Kure E.H., Andreassen A., Ovrebo S. Benzo[a]pyrene-albumin adducts in humans exposed to polycyclic aromatic hydrocarbons in an industrial area of Poland. Occupational and Environmental Medicine 1997, 54:662-666.
13. Lagerqvist A., Håkansson D., Prochazka G., Lundin C., Dreij K., Segerbäck D., Jernström B., Törnqvist M., Seidel A., Erixon K., Jenssen D. Both replication bypass fidelity and repair efficiency influence the yield of mutations per target dose in intact mammalian cells induced by benzo[a]pyrene-diol-epoxide and dibenzo[a,l]pyrene-diol-epoxide. DNA Repair (Amst) 2008, 7:1202-1212.
14. Lamba V., Lamba J., Yasuda K., Strom S., Davila J., Hancock M.L., Fackenthal J.D., Rogan P.K., Ring B., Wrighton S.A., Schuetz E.G. Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression. Journal of Pharmacology and Experimental Therapeutics 2003, 307:906-922.
15. Leng S., Dai Y., Niu Y., Pan Z., Li X., Cheng J., He F., Zheng Y. Effects of genetic polymorphisms of metabolic enzymes on cytokinesis-block micronucleus in peripheral blood lymphocyte among coke-oven workers. Cancer Epidemiology Biomarkers & Prevention 2004, 13:1631-1639.
16. Liu T.Y., Chung Y.T., Wang P.F., Chi C.W., Hsieh L.L. Safrole-DNA adducts in human peripheral blood - an association with areca quid chewing and CYP2E1 polymorphisms. Mutation Research 2004, 559:59-66.
17. Marczynski B., Rihs H.P., Rossbach B. Analysis of 8-oxo-7, 8-dihydro-2'-deoxyguanosine and DNA strand breaks in white blood cells of occupationally exposed workers: comparison with ambient monitoring, urinary metabolites and enzyme polymorphisms. Carcinogenesis 2002, 23:273-281.
18. Meyer M.J., Bechtold W.E. Protein adducts biomarkers: state of the art. Environmental Health Perspectives 1996, 104:879-882.
19. Nan H.M., Kim H., Lim H.S., Choi J.K., Kawarmoto T., Kang J.W., Lee C.H., Kim Y.D., Kwon E.H. Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations. Carcinogenesis 2001, 22:787-793.
20. Olive P.L., Banath J.P., Durand R.E. Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the comet assay. Radiation Research 1990, 122:86-94.
21. Padrós J., Pelletier E. In vivo formation of (+)-anti-benzo[a]pyrene diol-epoxide-plasma albumin adducts in fish. Marine Environmental Research 2000, 50:347-351.
22. Rendic S. Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 2002, 34:83-448.
23. Safe S.H. Hazard and risk assessment of chemical mixtures using the toxic equivalency factor approach. Environmental Health Perspectives 1998, 106:1051-1058.
24. Shimada T. Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons. Drug Metabolism and Pharmacokinetics 2006, 21:257-276.
25. Singh N.P., McCoy M.T., Tice R.R., Schneider E.L. A simple technique for quantization of low levels of DNA damage in individual cells. Experimental Cell Research 1988, 175:184-191.
26. Spink D.C., Wu S.J., Spink B.C., Hussain M.M., Vakaharia D.D., Pentecost B.T., Kaminsky L.S. Induction of CYP1A1 and CYP1B1 by benzo[k]fluoranthene and benzo[a]pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH metabolites. Toxicology and Applied Pharmacology 2008, 226:213-224.
27. Teixeira J.P., Gaspar J., Martinho G., Silva S., Rodrigues S., Mayan O., Martin E., Farmer P.B., Rueff J. Aromatic DNA adducts levels in coke oven workers: correlation with polymorphisms in genes GSTP1, GSTM1, GSTT1 and CYP1A1. Mutation Research 2002, 517:147-155.
28. Thompson A.L., Hurtubise R.J. Solid-matrix fluorescence quenching of benzo[e]pyrene and (+/-)-anti-dibenzo [a, l] pyrene diolepoxide-DNA adducts. Applied Spectroscopy 2005, 59:126-133.
29. Tung J.N., Wu H.H., Chiang C.C., Tsai Y.Y., Chou M.C., Lee H., Cheng Y.W. An association between BPDE-like DNA adducts levels and CYP1A1 and GSTM1 polymorphisma in pterygium. Molecular Vision 2010, 16:623-629.
30. Wang F., He Y., Guo H., Li J., Yang Y., Wu Z., Zheng H., Wu T. Genetic variants of nucleotide excision repair genes is associated with DNA damage in coke oven workers. Cancer Epidemiology, Biomarkers & Prevention 2010, 19:211-218.
31. Wang H., Campiglia A.D. Determination of polycyclic aromatic hydrocarbons in drinking water samples by solid-phase nanoextraction and high-performance liquid chromatography. Analytical Chemistry 2008, 80:8202-8209.
32. Wang S., Chanock S., Tang D., Li Z., Jedrychowski W., Perera F.P. Assessment of interactions between PAH exposure and genetic polymorphisms on PAH-DNA adducts in African American, Dominican, and Caucasian mothers and newborns. Cancer Epidemiology, Biomarkers & Prevention 2008, 17:405-413.
33. Washio I., Maeda M., Sugiura C., Shiga R., Yoshida M., Nonen S., Fujio Y., Azuma J. Cigarette smoke extract induces CYP2B6 through constitutive androstane receptor in hepatocytes. Drug Metabolism and Disposition 2011, 39:1-3.
34. Wei Y., Han I.K., Hu M., Shao M., Zhang J.J., Tang X. Personal exposure to particulate PAHs and anthraquinone and oxidative DNA damages in humans. Chemosphere 2010, 81:1280-1285.
35. Wills L.P., Jung D., Koehrn K., Zhu S., Willett K.L., Hinton D.E., Di Giulio R.T. Comparative chronic liver toxicity of benzo[a]pyrene in two populations of the atlantic killifish (Fundulus heteroclitus) with different exposure histories. Environmental Health Perspectives 2010, 118:1376-1381.
36. Wu M.T., Huang S.L., Ho C.K., Yeh Y.F., Christiani D.C. Cytochrome P450 1A1 Msp I polymorphism and urinary 1-hydroxypyrene concentrations in coke oven workers. Cancer Epidemiology Biomarkers & Prevention 1998, 7:823-829.
37. Yang X., Zheng J., Bai Y., Tian F., Yuan J., Sun J., Liang H., Guo L., Tan H., Chen W., Tanguay R.M., Wu T. Using lymphocyte and plasma Hsp70 as biomarkers for assessing coke oven exposure among steel workers. Environmental Health Perspectives 2007, 115:1573-1577.
38. Yuan Z., Liu Q., Zhang Y., Liu H., Zhao J., Zhu P. CYP2B6 gene single nucleotide polymorphisms and leukemia susceptibility. Annals of Hematology 2011, 90:293-299.
39. Zhu Z., Zhuang Z., Huang Y., Ji T. Design and application of image analysis system to single cell gel electrophoresis. Chinese Journal of Industrial Hygiene and Occupational Diseases 2001, 19:298-300.