CYP1A1 and CYP1B1 gene expression and DNA adduct formation in normal human mammary epithelial cells exposed to benzo[a]pyrene in the absence or presence of chlorophyllin

Cancer Letters

Volumn 292, Issue 2, 2010, Pages 254-260

  John, Kaarthik ^a,b   Divi, Rao L ^c   Keshava, Channa ^b   Orozco, Christine C ^c   Schockley, Marie E ^c   Richardson, Diana L ^b   Poirier, Miriam C ^c   Nath, Joginder ^a   Weston, Ainsley ^a,b  

^a WEST VIRGINIA UNIVERSITY   (United States)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

BPDE DNA chemiluminescence immunoassay; Chemoprevention; Chlorophyllin; DNA adducts; Polycyclic aromatic hydrocarbons; Real time PCR

Indexed keywords

10 (DEOXYGUANOSIN N2 YL) 7,8,9 TETRAHYDROBENZO[A]PYRENE; 7 T8 DIHYDROXY T 9, 10 EPOXY 7,8,9,10 TETRAHYDROBENZO[A]PYRENE; 7,8 TETRAHYDROXYBENZO[A]PYRENE 9,10 OXIDE; BENZO[A]PYRENE DERIVATIVE; CHLOROPHYLL; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DNA; UNCLASSIFIED DRUG; BENZO[A]PYRENE; CHLOROPHYLLIDE; CYTOCHROME P 450 CYP1B1; CYTOCHROME P-450 CYP1B1; UNSPECIFIC MONOOXYGENASE;

ARTICLE; BREAST EPITHELIUM; CHEMOLUMINESCENCE; CONTROLLED STUDY; DNA ADDUCT; DNA BINDING; GENE EXPRESSION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GENETICS; MAMMARY GLAND; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ARYL HYDROCARBON HYDROXYLASES; BENZO(A)PYRENE; CHLOROPHYLLIDES; CYTOCHROME P-450 CYP1A1; DNA ADDUCTS; HUMANS; MAMMARY GLANDS, HUMAN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 77951921299     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.12.008     Document Type: Article

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