Effects of genetic polymorphisms of metabolic enzymes on cytokinesis-block micronucleus in peripheral blood lymphocyte among coke-oven workers

Cancer Epidemiology Biomarkers and Prevention

Volumn 13, Issue 10, 2004, Pages 1631-1639

  Leng, Shuguang ^a   Dai, Yufei ^a   Niu, Yong ^a   Pan, Zufei ^b   Li, Xiaohua ^a   Cheng, Juan ^a   He, Fengsheng ^a   Zheng, Yuxin ^a  

^a CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b Benxi Beiying Iron and Steel Group Co Ltd   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1 HYDROXYPYRENE; ACYLTRANSFERASE; COKE; CREATININE; CYTOCHROME P450; ENZYME; EPOXIDE HYDROLASE; GLUTATHIONE TRANSFERASE; POLYCYCLIC AROMATIC HYDROCARBON; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (QUINONE); TYROSINE; VALINE;

ADULT; AGE; ARTICLE; ASSAY; CARCINOGENESIS; CHROMOSOME DAMAGE; CONTROLLED STUDY; CYTOKINESIS BLOCK MICROTUBULE ASSAY; FEMALE; GENE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTOXICITY; GENOTYPE; GSTM1 GENE; GSTP1 GENE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MEH GENE; OCCUPATIONAL EXPOSURE; PERIPHERAL LYMPHOCYTE; PHENOTYPE; PRIORITY JOURNAL; URINE LEVEL;

ACYLTRANSFERASES; ADULT; COKE; CYTOKINESIS; DNA DAMAGE; EPOXIDE HYDROLASES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; INCINERATION; LYMPHOCYTES; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MIDDLE AGED; OCCUPATIONAL EXPOSURE; POLYCYCLIC HYDROCARBONS, AROMATIC; POLYMORPHISM, GENETIC;

EID: 4944234018     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. IARC. Monographs on the evaluation of the carcinogenic risk of chemicals to humans. Vol. 32. Polycyclic aromatic hydrocarbons. Part 1. Chemical, environmental and experimental data. France: IARC; 1983.
2. IARC. Monographs on the evaluation of the carcinogenic risk of chemicals to humans. Vol. 34. Polycyclic aromatic hydrocarbons. Part 3. Industrial exposure in aluminum production, coal gasification, coke production, and iron and steel founding. France: IARC; 1984.
3. IARC. Monographs on the evaluation of the carcinogenic risk of chemicals to humans. Suppl. 7. France: IARC; 1987.
4. Jongeneelen FJ, Benchmark guideline for urinary 1-hydroxypyrene as biomarker of occupational exposure to polycyclic aromatic hydrocarbons. Ann Occup Hyg 2001;45:3-13.
5. Miller EC, Miller JA. Mechanisms of chemical carcinogenesis. Cancer 1981;47:1055-64.
6. International Programme on Chemical Safety. Environmental Health Criteria 202: selected non-heterocyclic polycyclic aromatic hydrocarbons. Geneva: WHO; 1998.
7. Daly AK, Cholerton S, Gregory W, Idle JR. Metabolic polymorphisms. Pharmacol Ther 1993,57:129-60.
8. Joseph P, Jaiswal AK. NAD(P)H:quinone oxidoreductasel (DT diaphorase) specifically prevents the formation of benzo[a]pyrene quinone-DNA adducts generated by cytochrome P4501A1 and P450 reductase. Proc Natl Acad Sci U S A 1994;91:8413-7.
9. Smith CA, Smith G, Wolf CR. Genetic polymorphisms in xenobiotic metabolism. Eur J Cancer 1994;30:1921-35.
10. Fenech M. The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human populations. Mutat Res 1993;285:35-44.
11. Fenech M. The in vitro micronucleus technique. Mutat Res 2000;455:81-95.
12. Fenech M. Chromosomal biomarkers of genomic instability relevant to cancer. Drug Discov Today 2002;7:1128-37.
13. Fenech M. Biomarkers of genetic damage for cancer epidemiology. Toxicology 2002;181-182:411-6.
14. Zhang J, Ichiba M, Hara K, et al. Urinary 1-hydroxypyrene in coke oven workers relative to exposure, alcohol consumption, and metabolic enzymes. Occup Environ Med 2001;58:716-21.
15. Rojas M, Cascorbi I, Alexandrov K, et al. Modulation of benzo[a]pyrene diolepoxide-DNA adduct levels in human white blood cells by CYP1A1, GSTM1 and GSTT1 polymorphism. Carcinogenesis 2000;21:35-41.
16. Kuljukka-Rabb T, Nylund L, Vaaranrinta R, et al. The effect of relevant genotypes on PAH exposure-related biomarkers. J Expo Anal Environ Epidemiol 2002;12:81-91.
17. Brescia G, Celotti L, Clonfero E, et al. The influence of cytochrome P450 1A1 and glutathione S-transferase M1 genotypes on biomarker levels in coke-oven workers. Arch Toxicol 1999;73:431-9.
18. Van Delft JH, Steenwinkel MS, van Asten JG, et al. Biological monitoring the exposure to polycyclic aromatic hydrocarbons of coke oven workers in relation to smoking and genetic polymorphisms for GSTM1 and GSTT1. Ann Occup Hyg 2001;45:395-408.
19. Viezzer C, Norppa H, Clonfero E, et al. Influence of GSTM1, GSTT1, GSTP1, and EPHX gene polymorphisms on DNA adduct level and HPRT mutant frequency in coke-oven workers. Mutat Res 1999;431:259-69.
20. Pavanello S, Gabbani G, Mastrangelo G, Brugnone F, Maccacaro G, Clonfero E. Influence of GSTM1 genotypes on anti-BPDE-DNA adduct levels in mononuclear white blood cells of humans exposed to PAH. Int Arch Occup Environ Health 1999;72:238-46.
21. Pastorelli R, Cerri A, Rozio M, et al. Benzo(a)pyrene diolepoxide adducts to albumin in workers exposed to polycyclic aromatic hydrocarbons: association with specific CYP1A1, GSTM1, GSTP1 and EHPX genotypes. Biomarkers 2001;6:357-74.
22. Tuominen R, Baranczewski P, Warholm M, Hagmar L, Moller L, Rannug A. Susceptibility factors and DNA adducts in peripheral blood mononuclear cells of aluminum smelter workers exposed to polycyclic aromatic hydrocarbons. Arch Toxicol 2002;76:178-86.
23. Carstensen U, Alexandrie AK, Hogstedt B, Rannug A, Bratt I, Hagmar L. B- and T-lymphocyte micronuclei in chimney sweeps with respect to genetic polymorphism for CYP1A1 and GST1 (class μ). Mutat Res 1993;289:187-95.
24. Nielsen PS, de Pater N, Okkels H, Autrup H. Environmental air pollution and DNA adducts in Copenhagen bus drivers-effect of GSTM1 and NAT2 genotypes on adduct levels. Carcinogenesis 1996;17:1021-7.
25. Gabbani G, Pavanello S, Nardini B, et al. Influence of metabolic genotype GSTM1 on levels of urinary mutagens in patients treated topically with coal tar. Mutat Res 1999;440:27-33.
26. Pastorelli R, Guanci M, Cerri A, et al. Impact of inherited polymorphisms in glutathione S-transferase M1, microsomal epoxide hydrolase, cytochrome P450 enzymes on DNA, and blood protein adducts of benzo(a)pyrene-diolepoxide. Cancer Epidemiol Biomarkers Prev 1998;7:703-9.
27. Carstensen U, Hou SM, Alexandrie AK, et al. Influence of genetic polymorphisms of biotransformation enzymes on gene mutations, strand breaks of deoxyribonucleic acid, and micronuclei in mononuclear blood cells and urinary 8-hydroxydeoxyguanosine in pot-room workers exposed to polyaromatic hydrocarbons. Scand J Work Environ Health 1999;25:351-60.
28. Carere A, Andreoli C, Galati R, et al. Biomonitoring of exposure to urban air pollutants: analysis of sister chromatid exchanges and DNA lesions in peripheral lymphocytes of traffic policemen. Mutat Res 2002;18:215-24.
29. Organic Methods Evaluation Branch, OSHA Analytical Laboratory. Coal tar pitch volatiles (CTPVs), coke oven emissions (COE), and selected polynuclear aromatic hydrocarbons (PAH). OSHA Method 58. Salt Lake City (UT): OSHA; 1986.
30. Jongeneelen FJ, Bos RP, Anzion RB, Theuws JL, Henderson PT. Biological monitoring of polycyclic aromatic hydrocarbons. Metabolites in urine. Scand J Work Environ Health 1986;12:137-43.
31. Li XH, Leng SG, Guo J, Guan L, Zheng YX. An improved high performance liquid chromatography method for determination of 1-hydroxypyrene in urine [in Chinese]. J Hyg Res 2003;32:616-7.
32. Hornung RW, Reed LD. Estimation of average concentration in the presence of nondetectable values. Appl Occup Environ Hyg 1990;5:46-51.
33. Fenech M, Chang WP, Kirsch-Volders M, Holland N, Bonassi S, Zeiger, E. Human MicroNucleus project. HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures. Mutat Res 2003;534:65-75.
34. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988;16:1215.
35. Hayashi SI, Watanabe J, Nakachi K, Kawajiri K. PCR detection of an A/G polymorphism within exon 7 of the CYP1A1 gene. Nucleic Acids Res 1991;19:4797.
36. Stephens EA, Taylor JA, Kaplan N, et al. Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese. Pharmacogenetics 1994;4:185-92.
37. Kato S, Shields PG, Caporaso NE, et al. Cytochrome P450IIE1 genetic polymorphisms, racial variation, and lung cancer risk. Cancer Res 1992;52:6712-5.
38. Saarikoski ST, Voho A, Reinikainen M, et al. Combined effect of polymorphic GST genes on individual susceptibility to lung cancer. Int J Cancer 1998;77:516-21.
39. Chan P, Monte DD, Jiang XQ. Identification of an NAD(P)H:quinine oxidoreductase polymorphism and its association with Parkinson's disease. Mov Disord 1997;12:26.
40. Zhong S, Wyllie AH, Barnes D, Wolf CR, Spurr NK. Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer. Carcinogenesis 1993;14:1821-4.
41. Katoh T, Nagata N, Kuroda Y, et al. Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) genetic polymorphism and susceptibility to gastric and colorectal adenocarcinoma. Carcinogenesis 1996;17:1855-9.
42. Hickman D, Sim E. N-acetyltransferase polymorphism. Comparison of phenotype and genotype in humans. Biochem Pharmacol 1991;42:1007-14.
43. Zhou W, Thurston SW, Liu G, et al. The interaction between microsomal epoxide hydrolase polymorphisms and cumulative cigarette smoking in different histological subtypes of lung cancer. Cancer Epidemiol Biomarkers Prev 2001;10:461-6.
44. Hassett C, Aicher L, Sidhu JS, Omiecinski CJ. Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants. Hum Mol Genet 1994;3:421-8. Erratum in: Hum Mol Genet 1994;3:1214.
45. Hassett C, Aicher L, Sidhu JS, Omiecinski CJ. Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants. Hum Mol Genet 1994;3:421-8. Erratum in: Hum Mol Genet 1994;3:1214.
46. Hassett C, Lin J, Carty CL, Laurenzana EM, Omiecinski CJ. Human hepatic microsomal epoxide hydrolase: comparative analysis of polymorphic expression. Arch Biochem Biophys 1997;337:275-83.
47. Salama SA, Sierra-Torres CH, Oh HY, Hamada FA, Au WW. Variant metabolizing gene alleles determine the genotoxicity of benzo[a]pyrene. Environ Mol Mutagen 2001;37:17-26.
48. Forni A, Guanti G, Bukvic N, Ferri G, Foa V. Cytogenetic studies in coke oven workers. Toxicol Lett 1996;88:185-9.
49. Buchet JP, Ferreira MJ, Burrion JB, et al. Tumor markers in serum, polyamines and modified nucleosides in urine, and cytogenetic aberrations in lymphocytes of workers exposed to polycyclic aromatic hydrocarbons. Am J Ind Med 1995;27:523-43.
50. Van Hummelen P, Gennart JP, Buchet JP, Lauwerys R, Kirsch-Volders M. Biological markers in PAH exposed workers and controls. Mutat Res 1993;300:231-9.
51. Leopardi P, Zijno A, Marcon F, et al. Analysis of micronuclei in peripheral blood lymphocytes of traffic wardens: effects of exposure, metabolic genotypes, and inhibition of excision repair in vitro by ARA-C. Environ Mol Mutagen 2003;41:126-30.
52. Bolognesi C, Merlo F, Rabboni R, Valerio F, Abbondandolo A. Cytogenetic biomonitoring in traffic police workers: micronucleus test in peripheral blood lymphocytes. Environ Mol Mutagen 1997;30:396-402.
53. Bonassi S, Fenech M, Lando C, et al. Human MicroNucleus project: international database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes. I. Effect of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei. Environ Mol Mutagen 2001;37:31-45.
54. Bonassi S, Neri M, Lando C, et al. HUMN collaborative group. Effect of smoking habit on the frequency of micronuclei in human lymphocytes: results from the Human MicroNucleus project. Mutat Res 2003;543:155-66.
55. Bolognesi C, Lando C, Forni A, et al. Chromosomal damage and aging: effect on micronuclei frequency in peripheral blood lymphocytes. Age Ageing 1999;28:393-7.
56. Yin L, Pu Y, Liu TY, Tung YH, Chen KW, Lin P. Genetic polymorphisms of NAD(P)H quinone oxidoreductase, CYP1A1 and microsomal epoxide hydrolase and lung cancer risk in Nanjing, China. Lung Cancer 2001;33:133-41.
57. Leng S, Song W, Wang Y, Liu Y, Zheng Y. The genetic polymorphisms of three kinds of glutathione S-transferases in Chinese Han population [in Chinese]. Zhonghua Yu Fang Yi Xue Za Zhi 2001;35:159-62.
58. Seidegard J, Vorachek WR, Pero RW, Pearson WR, Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion. Proc Natl Acad Sci U S A 1988;85:7293-7.
59. Lan Q, He X, Costa DJ, et al. Indoor coal combustion emissions, GSTM1 and GSTT1 genotypes, and lung cancer risk: a case-control study in Xuan Wei, China. Cancer Epidemiol Biomarkers Prev 2000;9:605-8.