메뉴 건너뛰기




Volumn 118, Issue 10, 2010, Pages 1376-1381

Comparative chronic liver toxicity of benzo[a]pyrene in two populations of the atlantic killifish (Fundulus heteroclitus) with different exposure histories

Author keywords

Benzo a pyrene; Fundulus heteroclitus; Hepatotoxicity; Polycyclic aromatic hydrocarbons

Indexed keywords

BENZO[A]PYRENE; CELL NUCLEUS DNA; CYTOCHROME P450 1A; MITOCHONDRIAL DNA;

EID: 77957905683     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.0901799     Document Type: Article
Times cited : (45)

References (50)
  • 1
    • 0019306958 scopus 로고
    • Covalent binding of polycyclic aromatic compounds to mitochondria and nuclear DNA
    • Allen JA, Coombs MM. 1980. Covalent binding of polycyclic aromatic compounds to mitochondria and nuclear DNA. Nature 287(5779):244-245.
    • (1980) Nature , vol.287 , Issue.5779 , pp. 244-245
    • Allen, J.A.1    Coombs, M.M.2
  • 2
    • 0034431467 scopus 로고    scopus 로고
    • Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction
    • Ayala-Torres S, Chen Y, Svoboda T, Rosenblatt J, Van Houten B. 2000. Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction. Methods 22(2):135-147.
    • (2000) Methods , vol.22 , Issue.2 , pp. 135-147
    • Ayala-Torres, S.1    Chen, Y.2    Svoboda, T.3    Rosenblatt, J.4    van Houten, B.5
  • 3
    • 0019306621 scopus 로고
    • Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxide derivative of benzo[a]pyrene
    • Backer JM, Weinstein IB. 1980. Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxide derivative of benzo[a]pyrene. Science 209(4453):297-299.
    • (1980) Science , vol.209 , Issue.4453 , pp. 297-299
    • Backer, J.M.1    Weinstein, I.B.2
  • 4
    • 0032190535 scopus 로고    scopus 로고
    • Long term trends in liver neoplasm epizootics of brown bullhead in the Black River, Ohio
    • Baumann PC, Harshbarger JC. 1998. Long term trends in liver neoplasm epizootics of brown bullhead in the Black River, Ohio. Environ Monit Assess 53(1):213-223.
    • (1998) Environ Monit Assess , vol.53 , Issue.1 , pp. 213-223
    • Baumann, P.C.1    Harshbarger, J.C.2
  • 5
    • 0025306582 scopus 로고
    • Relationship between liver tumors and age in brown bullhead populations from two Lake Erie tributaries
    • Baumann PC, Harshbarger JC, Hartman KJ. 1990. Relationship between liver tumors and age in brown bullhead populations from two Lake Erie tributaries. Sci Total Environ 94(1-2):71-87.
    • (1990) Sci Total Environ , vol.94 , Issue.1-2 , pp. 71-87
    • Baumann, P.C.1    Harshbarger, J.C.2    Hartman, K.J.3
  • 6
    • 0023824318 scopus 로고
    • Effects of polynuclear aromatic hydrocarbons on fishes and shellfish: An overview of research in Virginia
    • Bender ME, Hargis WJ Jr, Huggett RJ, Roberts MH Jr. 1988. Effects of polynuclear aromatic hydrocarbons on fishes and shellfish: an overview of research in Virginia. Mar Environ Res 24(1-4):237-241.
    • (1988) Mar Environ Res , vol.24 , Issue.1-4 , pp. 237-241
    • Bender, M.E.1    Hargis Jr., W.J.2    Huggett, R.J.3    Roberts Jr., M.H.4
  • 7
    • 84963450703 scopus 로고
    • Polycyclic aromatic hydrocarbons in surface sedicments from the Elizabeth River subesturary
    • Bieri RH, Hein C, Huggett RJ, Shou P, Slone H, Smith C, et al. 1986. Polycyclic aromatic hydrocarbons in surface sedicments from the Elizabeth River subesturary. Int J Environ Anal Chem 26(2):97-113.
    • (1986) Int J Environ Anal Chem , vol.26 , Issue.2 , pp. 97-113
    • Bieri, R.H.1    Hein, C.2    Huggett, R.J.3    Shou, P.4    Slone, H.5    Smith, C.6
  • 9
    • 49249120076 scopus 로고    scopus 로고
    • Nonadditive effects of PAHs on early vertebrate development: Mechanisms and implications for risk assessment
    • Billiard SM, Meyer JN, Wassenberg DM, Hodson PV, Di Giulio RT. 2008. Nonadditive effects of PAHs on early vertebrate development: mechanisms and implications for risk assessment. Toxicol Sci 105(1):5-23.
    • (2008) Toxicol Sci , vol.105 , Issue.1 , pp. 5-23
    • Billiard, S.M.1    Meyer, J.N.2    Wassenberg, D.M.3    Hodson, P.V.4    Di Giulio, R.T.5
  • 10
    • 0344412937 scopus 로고    scopus 로고
    • Benzo(a)pyrene quinones increase cell proliferation, generate reactive oxygen species, and transactivate the epidermal growth factor receptor in breast epithelial cells
    • Burdick AD, Davis JW II, Liu KJ, Hudson LG, Shi H, Monske ML, et al. 2003. Benzo(a)pyrene quinones increase cell proliferation, generate reactive oxygen species, and transactivate the epidermal growth factor receptor in breast epithelial cells. Cancer Res 63(22):7825-7833.
    • (2003) Cancer Res , vol.63 , Issue.22 , pp. 7825-7833
    • Burdick, A.D.1    Davis, J.W.I.I.2    Liu, K.J.3    Hudson, L.G.4    Shi, H.5    Monske, M.L.6
  • 11
    • 7444254094 scopus 로고    scopus 로고
    • Benzo[a]pyrene-induced immunotoxicity in Japanese medaka (Oryzias latipes): Relationship between lymphoid CYP1A activity and humoral immune suppression
    • Carlson EA, Li Y, Zelikoff JT. 2004. Benzo[a]pyrene-induced immunotoxicity in Japanese medaka (Oryzias latipes): relationship between lymphoid CYP1A activity and humoral immune suppression. Toxicol Appl Pharmacol 201(1):40-52.
    • (2004) Toxicol Appl Pharmacol , vol.201 , Issue.1 , pp. 40-52
    • Carlson, E.A.1    Li, Y.2    Zelikoff, J.T.3
  • 12
    • 0038768712 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
    • Denison MS, Nagy SR. 2003. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu Rev Pharmacol Toxicol 43:309-334.
    • (2003) Annu Rev Pharmacol Toxicol , vol.43 , pp. 309-334
    • Denison, M.S.1    Nagy, S.R.2
  • 13
    • 0033885507 scopus 로고    scopus 로고
    • Technical basis for narcotic chemicals and polycyclic aromatic hydrocarbon criteria. II. Mixtures and sediments
    • Di Toro DM, McGrath JA. 2000. Technical basis for narcotic chemicals and polycyclic aromatic hydrocarbon criteria. II. Mixtures and sediments. Environ Toxicol Chem 19(8):1971-1982.
    • (2000) Environ Toxicol Chem , vol.19 , Issue.8 , pp. 1971-1982
    • Di Toro, D.M.1    McGrath, J.A.2
  • 14
  • 15
    • 75149115740 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis
    • Fan Y, Boivin GP, Knudsen ES, Nebert DW, Xia Y, Puga A. 2010. The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis. Cancer Res 70(1):212-220.
    • (2010) Cancer Res , vol.70 , Issue.1 , pp. 212-220
    • Fan, Y.1    Boivin, G.P.2    Knudsen, E.S.3    Nebert, D.W.4    Xia, Y.5    Puga, A.6
  • 16
    • 0031716063 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor function in early vertebrates: Inducibility of cytochrome P450 1A in agnathan and elasmobranch fish
    • Hahn ME, Woodin BR, Stegeman JJ, Tillitt DE. 1998. Aryl hydrocarbon receptor function in early vertebrates: inducibility of cytochrome P450 1A in agnathan and elasmobranch fish. Comp Biochem Physiol C Comp Pharmacol Toxicol 120(1):67-75.
    • (1998) Comp Biochem Physiol C Comp Pharmacol Toxicol , vol.120 , Issue.1 , pp. 67-75
    • Hahn, M.E.1    Woodin, B.R.2    Stegeman, J.J.3    Tillitt, D.E.4
  • 17
    • 0021645158 scopus 로고
    • Effects of contaminated sediments and sediment-exposed effluent water on an estuarine fish: Acute toxicity
    • Hargis WJ Jr, Roberts MH Jr, Zwerner DE. 1984. Effects of contaminated sediments and sediment-exposed effluent water on an estuarine fish: acute toxicity. Mar Environ Res 14(1-4):337-354.
    • (1984) Mar Environ Res , vol.14 , Issue.1-4 , pp. 337-354
    • Hargis Jr., W.J.1    Roberts Jr., M.H.2    Zwerner, D.E.3
  • 18
    • 0036707694 scopus 로고    scopus 로고
    • Altering cytochrome P4501A activity affects polycyclic aromatic hydrocarbon metabolism and toxicity in rainbow trout (Oncorhynchus mykiss)
    • Hawkins SA, Billiard SM, Tabash SP, Brown RS, Hodson PV. 2002. Altering cytochrome P4501A activity affects polycyclic aromatic hydrocarbon metabolism and toxicity in rainbow trout (Oncorhynchus mykiss). Environ Toxicol Chem 21(9):1845-1853.
    • (2002) Environ Toxicol Chem , vol.21 , Issue.9 , pp. 1845-1853
    • Hawkins, S.A.1    Billiard, S.M.2    Tabash, S.P.3    Brown, R.S.4    Hodson, P.V.5
  • 20
    • 33845223174 scopus 로고    scopus 로고
    • Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A metabolism
    • Incardona JP, Day HL, Collier TK, Scholz NL. 2006. Developmental toxicity of 4-ring polycyclic aromatic hydrocarbons in zebrafish is differentially dependent on AH receptor isoforms and hepatic cytochrome P4501A metabolism. Toxicol Appl Pharmacol 217(3):308-321.
    • (2006) Toxicol Appl Pharmacol , vol.217 , Issue.3 , pp. 308-321
    • Incardona, J.P.1    Day, H.L.2    Collier, T.K.3    Scholz, N.L.4
  • 21
    • 63749105211 scopus 로고    scopus 로고
    • The long amplicon quantitative PCR for DNA damage assay as a sensitive method of assessing DNA damage in the environmental model, Atlantic killifish (Fundulus heteroclitus)
    • Jung D, Cho Y, Meyer JN, Di Giulio RT. 2009. The long amplicon quantitative PCR for DNA damage assay as a sensitive method of assessing DNA damage in the environmental model, Atlantic killifish (Fundulus heteroclitus). Comp Biochem Physiol C Comp Pharmacol Toxicol 149(2):182-186.
    • (2009) Comp Biochem Physiol C Comp Pharmacol Toxicol , vol.149 , Issue.2 , pp. 182-186
    • Jung, D.1    Cho, Y.2    Meyer, J.N.3    Di Giulio, R.T.4
  • 22
    • 3042749225 scopus 로고    scopus 로고
    • The complete mitochondrial genome of the javeline goby Acanthogobius hasta (Perciformes, Gobiidae) and phylogenetic considerations
    • Kim IC, Kweon HS, Kim YJ, Kim CB, Gye MC, Lee WO, et al. 2004. The complete mitochondrial genome of the javeline goby Acanthogobius hasta (Perciformes, Gobiidae) and phylogenetic considerations. Gene 336(2):147-153.
    • (2004) Gene , vol.336 , Issue.2 , pp. 147-153
    • Kim, I.C.1    Kweon, H.S.2    Kim, Y.J.3    Kim, C.B.4    Gye, M.C.5    Lee, W.O.6
  • 24
    • 0036752710 scopus 로고    scopus 로고
    • Patterns of heritability of decreased EROD activity and resistance to PCB 126-induced teratogenesis in laboratory-reared offspring of killifish (Fundulus heteroclitus) from a creosote-contaminated site in the Elizabeth River, VA, USA
    • Meyer JN, Di Giulio R. 2002. Patterns of heritability of decreased EROD activity and resistance to PCB 126-induced teratogenesis in laboratory-reared offspring of killifish (Fundulus heteroclitus) from a creosote-contaminated site in the Elizabeth River, VA, USA. Mar Environ Res 54(3-5):621-626.
    • (2002) Mar Environ Res , vol.54 , Issue.3-5 , pp. 621-626
    • Meyer, J.N.1    Di Giulio, R.2
  • 25
    • 0038376984 scopus 로고    scopus 로고
    • Heritable adaptation and associated fitness costs in killifish (Fundulus heteroclitus) inhabiting a polluted estuary
    • Meyer JN, Di Giulio R. 2003. Heritable adaptation and associated fitness costs in killifish (Fundulus heteroclitus) inhabiting a polluted estuary. Ecol Appl 13(2):490-503.
    • (2003) Ecol Appl , vol.13 , Issue.2 , pp. 490-503
    • Meyer, J.N.1    Di Giulio, R.2
  • 26
    • 0035996060 scopus 로고    scopus 로고
    • Cytochrome P4501A (CYP1A) in killifish (Fundulus heteroclitus): Heritability of altered expression and relationship to survival in contaminated sediments
    • Meyer JN, Nacci DE, Di Giulio RT. 2002. Cytochrome P4501A (CYP1A) in killifish (Fundulus heteroclitus): heritability of altered expression and relationship to survival in contaminated sediments. Toxicol Sci 68(1):69-81.
    • (2002) Toxicol Sci , vol.68 , Issue.1 , pp. 69-81
    • Meyer, J.N.1    Nacci, D.E.2    Di Giulio, R.T.3
  • 27
    • 0141736888 scopus 로고    scopus 로고
    • Expression and inducibility of aryl hydrocarbon receptor pathway genes in wild-caught killifish (Fundulus heteroclitus) with different contaminant-exposure histories
    • Meyer JN, Wassenberg DM, Karchner SI, Hahn ME, Di Giulio R. 2003. Expression and inducibility of aryl hydrocarbon receptor pathway genes in wild-caught killifish (Fundulus heteroclitus) with different contaminant-exposure histories. Environ Toxicol Chem 22(10):2337-2343.
    • (2003) Environ Toxicol Chem , vol.22 , Issue.10 , pp. 2337-2343
    • Meyer, J.N.1    Wassenberg, D.M.2    Karchner, S.I.3    Hahn, M.E.4    Di Giulio, R.5
  • 28
    • 0025364277 scopus 로고
    • Overview of studies on liver carcinogenesis in English sole from Puget Sound; evidence of a xenobiotic chemical etiology I: Pathology and epizootiology
    • Myers MS, Landahl JT, Krahn MM, Johnson LL, McCain BB. 1990. Overview of studies on liver carcinogenesis in English sole from Puget Sound; evidence of a xenobiotic chemical etiology I: pathology and epizootiology. Sci Total Environ 94(1-2):33-50.
    • (1990) Sci Total Environ , vol.94 , Issue.1-2 , pp. 33-50
    • Myers, M.S.1    Landahl, J.T.2    Krahn, M.M.3    Johnson, L.L.4    McCain, B.B.5
  • 29
    • 0036128806 scopus 로고    scopus 로고
    • Effects of benzo[a]pyrene exposure on a fish population resistant to the toxic effects of dioxin-like compounds
    • Nacci DE, Kohan M, Pelletier M, George E. 2002. Effects of benzo[a]pyrene exposure on a fish population resistant to the toxic effects of dioxin-like compounds. Aquat Toxicol 57(4):203-215.
    • (2002) Aquat Toxicol , vol.57 , Issue.4 , pp. 203-215
    • Nacci, D.E.1    Kohan, M.2    Pelletier, M.3    George, E.4
  • 30
    • 0032821287 scopus 로고    scopus 로고
    • A multihit, multistage model of chemical carcinogenesis
    • Owens DM, Wei SJC, Smart RC. 1999. A multihit, multistage model of chemical carcinogenesis. Carcinogenesis 20(9):1837-1844.
    • (1999) Carcinogenesis , vol.20 , Issue.9 , pp. 1837-1844
    • Owens, D.M.1    Wei, S.J.C.2    Smart, R.C.3
  • 31
    • 0036707686 scopus 로고    scopus 로고
    • Fish (Fundulus heteroclitus) populations with different exposure histories differ in tolerance of creosote-contaminated sediments
    • Ownby DR, Newman MC, Mulvey M, Vogelbein WK, Unger MA, Arzayus LF. 2002. Fish (Fundulus heteroclitus) populations with different exposure histories differ in tolerance of creosote-contaminated sediments. Environ Toxicol Chem 21(9):1897-1902.
    • (2002) Environ Toxicol Chem , vol.21 , Issue.9 , pp. 1897-1902
    • Ownby, D.R.1    Newman, M.C.2    Mulvey, M.3    Vogelbein, W.K.4    Unger, M.A.5    Arzayus, L.F.6
  • 32
    • 0242268495 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor 2 mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin developmental toxicity in zebrafish
    • Prasch AL, Teraoka H, Carney SA, Dong W, Hiraga T, Stegeman JJ, et al. 2003. Aryl hydrocarbon receptor 2 mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin developmental toxicity in zebrafish. Toxicol Sci 76(1):138-150.
    • (2003) Toxicol Sci , vol.76 , Issue.1 , pp. 138-150
    • Prasch, A.L.1    Teraoka, H.2    Carney, S.A.3    Dong, W.4    Hiraga, T.5    Stegeman, J.J.6
  • 33
    • 0021245420 scopus 로고
    • The hepatocarcinogenicity of diethylnitrosamine to rainbow trout and its enhancement by Aroclor-1242 and Aroclor-1254
    • Shelton DW, Hendricks JD, Bailey GS. 1984. The hepatocarcinogenicity of diethylnitrosamine to rainbow trout and its enhancement by Aroclor-1242 and Aroclor-1254. Toxicol Lett 22(1):27-31.
    • (1984) Toxicol Lett , vol.22 , Issue.1 , pp. 27-31
    • Shelton, D.W.1    Hendricks, J.D.2    Bailey, G.S.3
  • 34
    • 1142275258 scopus 로고    scopus 로고
    • Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1
    • Shimada T, Fujii-Kuriyama Y. 2004. Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1. Cancer Sci 95(1):1-6.
    • (2004) Cancer Sci , vol.95 , Issue.1 , pp. 1-6
    • Shimada, T.1    Fujii-Kuriyama, Y.2
  • 36
    • 0029877953 scopus 로고    scopus 로고
    • The model Ah-receptor agonist beta-naphthoflavone inhibits aflatoxin B-1-DNA binding in vivo in rainbow trout at dietary levels that do not induce CYP1A enzymes
    • Takahashi N, Harttig U, Williams DE, Bailey GS. 1996. The model Ah-receptor agonist beta-naphthoflavone inhibits aflatoxin B-1-DNA binding in vivo in rainbow trout at dietary levels that do not induce CYP1A enzymes. Carcinogenesis 17(1):79-87.
    • (1996) Carcinogenesis , vol.17 , Issue.1 , pp. 79-87
    • Takahashi, N.1    Harttig, U.2    Williams, D.E.3    Bailey, G.S.4
  • 37
    • 32644442996 scopus 로고    scopus 로고
    • Impact of Cyp1a2 or Ahr gene knockout in mice: Implications for biomonitoring studies
    • Talaska G, Ginsburg D, LaDow K, Puga A, Dalton T, Warshawsky D. 2006. Impact of Cyp1a2 or Ahr gene knockout in mice: implications for biomonitoring studies. Toxicol Lett 162(2-3):246-249.
    • (2006) Toxicol Lett , vol.162 , Issue.2-3 , pp. 246-249
    • Talaska, G.1    Ginsburg, D.2    Ladow, K.3    Puga, A.4    Dalton, T.5    Warshawsky, D.6
  • 38
    • 0036669004 scopus 로고    scopus 로고
    • Metabolic disturbances in fish exposed to sodium pentachlorophenate (NaPCP) and 3,3',4,4',5-pentachlorobiphenyl (PCB126), individually or combined
    • Tugiyono, Gagnon MM. 2002. Metabolic disturbances in fish exposed to sodium pentachlorophenate (NaPCP) and 3,3',4,4',5-pentachlorobiphenyl (PCB126), individually or combined. Comp Biochem Physiol C Comp Pharmacol Toxicol 132(4):425-435.
    • (2002) Comp Biochem Physiol C Comp Pharmacol Toxicol , vol.132 , Issue.4 , pp. 425-435
    • Tugiyono1    Gagnon, M.M.2
  • 39
    • 0031062287 scopus 로고    scopus 로고
    • Route-specific cellular expression of cytochrome P4501A (CYP1A) in fish (Fundulus heteroclitus) following exposure to aqueous and dietary benzo[a]pyrene
    • Van Veld PA, Vogelbein WK, Cochran MK, Goksoyr A, Stegeman JJ. 1997. Route-specific cellular expression of cytochrome P4501A (CYP1A) in fish (Fundulus heteroclitus) following exposure to aqueous and dietary benzo[a]pyrene. Toxicol Appl Pharmacol 142(2):348-359.
    • (1997) Toxicol Appl Pharmacol , vol.142 , Issue.2 , pp. 348-359
    • van Veld, P.A.1    Vogelbein, W.K.2    Cochran, M.K.3    Goksoyr, A.4    Stegeman, J.J.5
  • 40
    • 0022470467 scopus 로고
    • Comparative metabolism of benzo(a)pyrene and covalent binding to hepatic DNA in English sole, starry flounder, and rat
    • Varanasi U, Nishimoto M, Reichert WL, Le Eberhart BT. 1986. Comparative metabolism of benzo(a)pyrene and covalent binding to hepatic DNA in English sole, starry flounder, and rat. Cancer Res 46(8):3817-3824.
    • (1986) Cancer Res , vol.46 , Issue.8 , pp. 3817-3824
    • Varanasi, U.1    Nishimoto, M.2    Reichert, W.L.3    Le Eberhart, B.T.4
  • 41
    • 0033385381 scopus 로고    scopus 로고
    • Hepatoblastomas in the mummichog, Fundulus heteroclitus (L.), from a creosote-contaminated environment: A histologic, ultrastructural and immunohistochemical study
    • Vogelbein WK, Fournie JW, Cooper PS, Van Veld PA. 1999. Hepatoblastomas in the mummichog, Fundulus heteroclitus (L.), from a creosote-contaminated environment: a histologic, ultrastructural and immunohistochemical study. J Fish Dis 22(6):419-431.
    • (1999) J Fish Dis , vol.22 , Issue.6 , pp. 419-431
    • Vogelbein, W.K.1    Fournie, J.W.2    Cooper, P.S.3    van Veld, P.A.4
  • 42
    • 0025047342 scopus 로고
    • Hepatic neoplasms in the mummichog Fundulus heteroclitus from a creosote contaminated site
    • Vogelbein WK, Fournie JW, Vanveld PA, Huggett RJ. 1990. Hepatic neoplasms in the mummichog Fundulus heteroclitus from a creosote contaminated site. Cancer Res 50(18):5978-5986.
    • (1990) Cancer Res , vol.50 , Issue.18 , pp. 5978-5986
    • Vogelbein, W.K.1    Fournie, J.W.2    Vanveld, P.A.3    Huggett, R.J.4
  • 43
    • 33644938010 scopus 로고    scopus 로고
    • Liver carcinogenesis in a non-migratory fish: The association with polycyclic aromatic hydrocarbon exposure
    • Vogelbein WK, Unger MA. 2006. Liver carcinogenesis in a non-migratory fish: the association with polycyclic aromatic hydrocarbon exposure. Bull Eur Assoc Fish Pathol 26(1):11-20.
    • (2006) Bull Eur Assoc Fish Pathol , vol.26 , Issue.1 , pp. 11-20
    • Vogelbein, W.K.1    Unger, M.A.2
  • 44
    • 77957903427 scopus 로고    scopus 로고
    • The Elizabeth River Monitoring Program 2006-2007: Association between Mummichog Liver Histopathology and Sediment Chemical Contamination
    • VA: Virginia Department of Environmental Quality
    • Vogelbein WK, Unger M, Gauthier D. 2008. The Elizabeth River Monitoring Program 2006-2007: Association between Mummichog Liver Histopathology and Sediment Chemical Contamination. Richmond, VA: Virginia Department of Environmental Quality.
    • (2008) Richmond
    • Vogelbein, W.K.1    Unger, M.2    Gauthier, D.3
  • 45
    • 2942544706 scopus 로고    scopus 로고
    • Teratogenesis in Fundulus heteroclitus embryos exposed to a creosote-contaminated sediment extract and CYP1A inhibitors
    • Wassenberg DM, Di Giulio RT. 2004. Teratogenesis in Fundulus heteroclitus embryos exposed to a creosote-contaminated sediment extract and CYP1A inhibitors. Mar Environ Res 58(2-5):163-168.
    • (2004) Mar Environ Res , vol.58 , Issue.2-5 , pp. 163-168
    • Wassenberg, D.M.1    Di Giulio, R.T.2
  • 46
    • 0032520718 scopus 로고    scopus 로고
    • Inhibition of CYP1A1-dependent activity by the polynuclear aromatic hydrocarbon (PAH) fluoranthene
    • Willett KL, Randerath K, Zhou GD, Safe SH. 1998. Inhibition of CYP1A1-dependent activity by the polynuclear aromatic hydrocarbon (PAH) fluoranthene. Biochem Pharmacol 55(6):831-839.
    • (1998) Biochem Pharmacol , vol.55 , Issue.6 , pp. 831-839
    • Willett, K.L.1    Randerath, K.2    Zhou, G.D.3    Safe, S.H.4
  • 47
    • 77953686688 scopus 로고    scopus 로고
    • Characterization of the recalcitrant CYP1 phenotype found in Atlantic killifish (Fundulus heteroclitus) inhabiting a Superfund site on the Elizabeth River, VA
    • Wills LP, Matson CW, Landon CD, Di Giulio RT. 2010. Characterization of the recalcitrant CYP1 phenotype found in Atlantic killifish (Fundulus heteroclitus) inhabiting a Superfund site on the Elizabeth River, VA. Aquat Toxicol 99(1):33-41.
    • (2010) Aquat Toxicol , vol.99 , Issue.1 , pp. 33-41
    • Wills, L.P.1    Matson, C.W.2    Landon, C.D.3    Di Giulio, R.T.4
  • 48
    • 64149120732 scopus 로고    scopus 로고
    • Effect of CYP1A inhibition on the biotransformation of benzo[a]pyrene in two populations of Fundulus heteroclitus with different exposure histories
    • Wills LP, Zhu S, Willett KL, Di Giulio RT. 2009. Effect of CYP1A inhibition on the biotransformation of benzo[a]pyrene in two populations of Fundulus heteroclitus with different exposure histories. Aquat Toxicol 92(3):195-201.
    • (2009) Aquat Toxicol , vol.92 , Issue.3 , pp. 195-201
    • Wills, L.P.1    Zhu, S.2    Willett, K.L.3    Di Giulio, R.T.4
  • 49
    • 0021985757 scopus 로고
    • Study of the carcinogenic mechanism for polycyclic aromatic hydrocarbons-extended bay region theory and its quantitative model
    • Yan LS. 1985. Study of the carcinogenic mechanism for polycyclic aromatic hydrocarbons-extended bay region theory and its quantitative model. Carcinogenesis 6(1):1-6.
    • (1985) Carcinogenesis , vol.6 , Issue.1 , pp. 1-6
    • Yan, L.S.1
  • 50
    • 39149090667 scopus 로고    scopus 로고
    • Simultaneous determination of benzo[a]pyrene and eight of its metabolites in Fundulus heteroclitus bile using ultra-performance liquid chromatography with mass spectrometry
    • Zhu S, Li L, Thornton C, Carvalho P, Avery BA, Willett KL. 2008. Simultaneous determination of benzo[a]pyrene and eight of its metabolites in Fundulus heteroclitus bile using ultra-performance liquid chromatography with mass spectrometry. J Chromatogr B 863(1):141-149.
    • (2008) J Chromatogr B , vol.863 , Issue.1 , pp. 141-149
    • Zhu, S.1    Li, L.2    Thornton, C.3    Carvalho, P.4    Avery, B.A.5    Willett, K.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.