Expression analysis of the CLCA gene family in mouse and human with emphasis on the nervous system

BMC Developmental Biology

Volumn 9, Issue 1, 2009, Pages

  Piirsoo, Marko ^a   Meijer, Dies ^b   Timmusk, Tnis ^a  

^a TALLINN UNIVERSITY OF TECHNOLOGY   (Estonia)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE CHANNEL; MESSENGER RNA; PRIMER DNA;

ADULT; ANIMAL; ARTICLE; CLASSIFICATION; COMPARATIVE STUDY; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; IN SITU HYBRIDIZATION; METABOLISM; MOUSE; MULTIGENE FAMILY; NERVOUS SYSTEM; NUCLEOTIDE SEQUENCE; PRENATAL DEVELOPMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPECIES DIFFERENCE;

ADULT; ANIMALS; BASE SEQUENCE; CHLORIDE CHANNELS; DNA PRIMERS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; IN SITU HYBRIDIZATION; MICE; MULTIGENE FAMILY; NERVOUS SYSTEM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPECIES SPECIFICITY;

EID: 61849138403     PISSN: None     EISSN: 1471213X     Source Type: Journal    
DOI: 10.1186/1471-213X-9-10     Document Type: Article

References (22)

1. Calcium-activated chloride channels. C Hartzell I Putzier J Arreola, Annu Rev Physiol 2005 67 719 58 10.1146/annurev.physiol.67.032003.154341 15709976
2. Molecular characteristics and functional diversity of CLCA family members. BU Pauli M Abdel-Ghany HC Cheng AD Gruber HA Archibald RC Elble, Clin Exp Pharmacol Physiol 2000 27 11 901 5 10.1046/j.1440-1681.2000.03358.x 11071307
3. Ca(2+)-activated Cl- channels in Ehrlich ascites tumor cells are distinct from mClca1, 2 and 3. J Papassotiriou J Eggermont G Droogmans B Nilius, Pflugers Arch 2001 442 2 273 9 10.1007/s004240100526 11417225
4. Molecular cloning and biochemical characterization of a truncated, secreted member of the human family of Ca2+-activated Cl- channels. AD Gruber BU Pauli, Biochim Biophys Acta 1999 1444 3 418 23 10095065
5. hCLCA1 and mClca3 are secreted non-integral membrane proteins and therefore are not ion channels. A Gibson AP Lewis K Affleck AJ Aitken E Meldrum N Thompson, J Biol Chem 2005 280 29 27205 12 Epub 2005 May 25 10.1074/jbc.M504654200 15919655
6. Novel conserved hydrolase domain in the CLCA family of alleged calcium-activated chloride channels. K Pawowski M Lepistö N Meinander U Sivars M Varga E Wieslander, Proteins 2006 63 3 424 39 10.1002/prot.20887 16470849
7. The breast cancer beta 4 integrin and endothelial human CLCA2 mediate lung metastasis. M Abdel-Ghany HC Cheng RC Elble BU Pauli, J Biol Chem 2001 276 27 25438 46 10.1074/jbc.M100478200 11320086
8. The interacting binding domains of the beta(4) integrin and calcium-activated chloride channels (CLCAs) in metastasis. M Abdel-Ghany HC Cheng RC Elble H Lin J DiBiasio BU Pauli, J Biol Chem 2003 278 49 49406 16 10.1074/jbc.M309086200 14512419
9. Tumor suppression by a proapoptotic calcium-activated chloride channel in mammary epithelium. RC Elble BU Pauli, J Biol Chem 2001 276 44 40510 7 10.1074/jbc.M104821200 11483609
10. Role of gob-5 in mucus overproduction and airway hyperresponsiveness in asthma. A Nakanishi S Morita H Iwashita Y Sagiya Y Ashida H Shirafuji Y Fujisawa O Nishimura M Fujino, Proc Natl Acad Sci USA 2001 98 9 5175 80 11296262 10.1073/pnas.081510898
11. Association of the hCLCA1 gene with childhood and adult asthma. F Kamada Y Suzuki C Shao M Tamari K Hasegawa T Hirota M Shimizu N Takahashi XQ Mao S Doi, Genes Immun 2004 5 7 540 7 10.1038/sj.gene.6364124 15318163
12. The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis. M Ritzka F Stanke S Jansen AD Gruber L Pusch S Woelfl HJ Veeze DJ Halley B Tümmler, Hum Genet 2004 115 6 483 91 10.1007/s00439-004- 1190-y 15490240
13. Real-time RT-PCR quantitation of mClca1 and mClca2 reveals differentially regulated expression in pre- and postnatal murine tissues. I Leverkoehne BA Horstmeier G von Samson-Himmelstjerna BJ Scholte AD Gruber, Histochem Cell Biol 2002 118 1 11 7 12122442
14. The murine mClca3 (alias gob-5) protein is located in the mucin granule membranes of intestinal, respiratory, and uterine goblet cells. I Leverkoehne AD Gruber, J Histochem Cytochem 2002 50 6 829 38 12019299
15. Molecular and functional characterization of a murine calcium-activated chloride channel expressed in smooth muscle. RC Elble G Ji K Nehrke J DeBiasio PD Kingsley MI Kotlikoff BU Pauli, J Biol Chem 2002 277 21 18586 91 10.1074/jbc.M200829200 11896056
16. Molecular and functional analyses of two new calcium-activated chloride channel family members from mouse eye and intestine. SR Evans WB Thoreson CL Beck, J Biol Chem 2004 279 40 41792 800 15284223 10.1074/jbc.M408354200
17. A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system. J Laurén MS Airaksinen M Saarma T Timmusk, Genomics 2003 81 4 411 21 10.1016/S0888-7543(03)00030-2 12676565
18. Differential expression of calcium-activated chloride channels (CLCA) gene family members in the small intestine of cystic fibrosis mouse models. I Leverkoehne H Holle F Anton AD Gruber, Histochem Cell Biol 2006 126 2 239 50 10.1007/s00418-006-0164-7 16514548
19. Expression of three distinct families of calcium-activated chloride channel genes in the mouse dorsal root ganglion. M Al-Jumaily A Kozlenkov I Mechaly A Fichard V Matha F Scamps J Valmier P Carroll, Neurosci Bull 2007 23 5 293 9 10.1007/s12264-007-0044-8 17952139
20. Cloning and expression of Ca2+-activated chloride channel from rat brain. SM Jeong HK Park IS Yoon JH Lee JH Kim CG Jang CJ Lee SY Nah, Biochem Biophys Res Commun 2005 334 2 569 76 10.1016/j.bbrc.2005.06.122 16023076
21. Cloning and heterologous expression of a Ca2+-activated chloride channel isoform from rat brain. IS Yoon SM Jeong SN Lee JH Lee JH Kim MK Pyo JH Lee BH Lee SH Choi H Rhim H Choe SY Nah, Biol Pharm Bull 2006 29 11 2168 73 10.1248/bpb.29.2168 17077509
22. Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea. M Agnel T Vermat JM Culouscou, FEBS Lett 1999 455 3 295 301 10.1016/S0014-5793(99)00891-1 10437792