Mechanism of apoptotosis induced by ortho-topolin riboside in human hepatoma cell line SMMC-7721

Food and Chemical Toxicology

Volumn 50, Issue 6, 2012, Pages 1962-1968

  Wang, Li ^a   Sun, Chao ^b,c   Wang, Zhen Hua ^b   Guo, Guang Qin ^a  

^a LANZHOU UNIVERSITY   (China)

^b INSTITUTE OF MODERN PHYSICS   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Adenosine kinase; Akt; Apoptosis; ERK 1 2; Human hepatoma cell; Ortho topolin riboside

Indexed keywords

2 TOPOLIN RIBOSIDE; ADENOSINE KINASE INHIBITOR; BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 9; CYTOCHROME C; CYTOKININ; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL STRAIN SMMC 7721; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; FLOW CYTOMETRY; HEPATOMA CELL; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PROTEIN SECRETION; UPREGULATION; WESTERN BLOTTING;

ADENOSINE KINASE; AMINO ACID CHLOROMETHYL KETONES; APOPTOSIS; BLOTTING, WESTERN; CASPASE 9; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; CYTOKININS; FLOW CYTOMETRY; HUMANS; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIALS; MITOCHONDRIAL MEMBRANES; MITOGEN-ACTIVATED PROTEIN KINASES; NUCLEOSIDES; OLIGOPEPTIDES; ONCOGENE PROTEIN V-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

EID: 84860185190     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.03.053     Document Type: Article

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