p38 Kinase is a negative regulator of angiotensin II signal transduction in vascular smooth muscle cells effects on Na+/H+ exchange and ERK1/2

Circulation Research

Volumn 83, Issue 8, 1998, Pages 824-831

  Kusuhara, Masatoshi ^a   Takahashi, Eiichi ^a   Peterson, Timothy E ^a   Abe, Jun Ichi ^a   Ishida, Mari ^d   Han, Jiahuai ^b   Ulevitch, Richard ^b   Berk, Bradford C ^c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^d NONE

Author keywords

Angiotensin II; Mitogen activated protein kinase; Na+ H+ exchange; Vascular smooth muscle

Indexed keywords

ANGIOTENSIN; MITOGEN ACTIVATED PROTEIN KINASE;

ADAPTATION; ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; ENZYME ACTIVATION; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; NONHUMAN; OSMOTIC STRESS; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; PROTON SODIUM EXCHANGE; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

EID: 0032547814     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.83.8.824     Document Type: Article

References (37)

1. Schmitz U, Berk BC. Angiotensin II signal transduction: stimulation of multiple mitogen-activated protein kinase pathways. Trends Endocrinol Metab. 1997;8:261-266.
2. Berk B, Corson M. Angiotensin II signal transduction in vascular smooth muscle: role of tyrosine kinases. Circ Res. 1997;80:607-616.
3. Duff JL, Berk BC, Corson MA. Angiotensin II stimulates the pp44 and pp42 mitogen-activated protein kinases in cultured rat aortic smooth muscle cells. Biochem Biophys Res Commun. 1992;188:257-264.
4. Schmitz U, Ishida T, Ishida M, Surapisitchat J, Hasham MI, Pelech S, Berk BC. Angiotensin II stimulates p21-activated kinase in vascular smooth muscle cells: role in activation of JNK. Circ Res. 1998;82: 1272-1278.
5. Berk BC, Aronow MS, Brock TA, Cragoe E Jr, Gimbrone MA Jr, Alexander RW. Angiotensin II-stimulated Na+/H+ exchange in cultured vascular smooth muscle cells: evidence for protein kinase C-dependent and -independent pathways. J Biol Chem. 1987;262:5057-5064.
6. Berk BC, Canessa M, Vallega G, Alexander RW. Agonist-mediated changes in intracellular pH: role in vascular smooth muscle cell function. J Cardiovasc Pharmacol. 1988;5:S104-S114.
7. + exchange inhibitors decrease neointimal formation after rat carotid injury. Circ Res. 1993;73:269-275.
8. + antiport. J Biol Chem. 1991;266:15406-15413.
9. Berk BC, Vallega G, Muslin AJ, Gordon HM, Canessa M, Alexander RW. Spontaneously hypertensive rat vascular smooth muscle cells in culture exhibit increased growth and Na+/H+ exchange. J Clin Invest. 1989;83:822-829.
10. Siczkowski M, Davies JE, Ng LL. Na+-H+ exchanger isoform 1 phosphorylation in normal Wistar-Kyoto and spontaneously hypertensive rats. Circ Res. 1995;76:825-831.
11. Lucchesi PA, DeRoux N, Berk BC. Na+-H+ exchanger expression in vascular smooth muscle of spontaneously hypertensive and Wistar-Kyoto rats. Hypertension. 1994;24:734-738.
12. + exchanger kinase. Circ Res. 1997;81:268-273.
13. Abe J, Kusuhara M, Ulevitch RJ, Berk BC, Lee JD. Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase. J Biol Chem. 1996;271:16586-16590.
14. Han J, Lee JD, Bibbs L, Ulevitch RJ. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science. 1994;265: 808-811.
15. Brewster JL, de Valoir T, Dwyer ND, Winter E, Gustin MC. An osmosensing signal transduction pathway in yeast. Science. 1993;259: 1760-1763.
16. Wang H, Silva NL, Lucchesi PA, Haworth R, Wang K, Michalak M, Pelech S, Fliegel L. Phosphorylation and regulation of the Na+/H+ exchanger through mitogen-activated protein kinase. Biochemistry. 1997; 36:9151-9158.
17. Shrode LD, Ruble EA, Woodgett JR, Grinstein S. Cytosolic alkalinization increases stress-activated protein kinase/c-Jun NH2-terminal kinase (SAPK/JNK) activity and p38 mitogen-activated protein kinase activity by a calcium-independent mechanism. J Biol Chem. 1997;272: 13653-13659.
18. + exchanger in human platelets. J Biol Chem. 1996; 271:16494-16499.
19. Bianchini L, L' Allemain G, Pouysségur J. The p42/p44 mitogen-activated protein kinase cascade is determinant in mediating activation of the Na+/H+ exchanger (NHE1 isoform) in response to growth factors. J Biol Chem. 1997;272:271-279.
20. Duff JL, Monia BP, Berk BC. Mitogen-activated protein (MAP) kinase is regulated by the MAP kinase phosphatase (MKP-1) in vascular smooth muscle cells: effect of actinomycin D and antisense oligonucleotides. J Biol Chem. 1995;270:7161-7166.
21. Mitsuka M, Berk BC. Long-term regulation of Na(+)-H+ exchange in vascular smooth muscle cells: role of protein kinase C. Am J Physiol. 1991;260:C562-C569.
22. Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, McNulty D, Blumenthal MJ, Heys JR, Landvatter SW, Strickler JE, McLaughlin MM, Ivo RS, Fisher SM, Livi GP, White JR, Adams JL, Young PR. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature. 1994;372:739-746.
23. c-src in vascular smooth muscle cells. Circ Res. 1995;77:1053-1059.
24. Berk BC, Vallega G, Griendling KK, Gordon JB, Cragoe EJ Jr, Canessa M, Alexander RW. Effects of glucocorticoids on Na+/H+ exchange and growth in cultured vascular smooth muscle cells. J Cell Physiol. 1988; 137:391-401.
25. Berk BC, Brock TA, Gimbrone MA Jr, Alexander RW. Early agonist-mediated ionic events in cultured vascular smooth muscle cells: calcium mobilization is associated with intracellular acidification. J Biol Chem. 1987;262:5065-5072.
26. Zhang C, Baumgartner RA, Yamada K, Beaven MA. Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-alpha and release of arachidonic acid in mast cells: indications of communication between p38 and p42 MAP kinases. J Biol Chem. 1997;272: 13397-402.
27. + exchange through distinct Cdc42-dependent and RhoA-dependent pathways. J Biol Chem. 1996;271:6152-6158.
28. Raingeaud J, Gupta S, Rogers JS, Dickens M, Han J, Ulevitch RJ, Davis RJ. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem. 1995;270:7420-7426.
29. Marrero MB, Schieffer B, Paxton WG, Heerdt L, Berk BC, Delafontaine P, Bernstein KE. Direct stimulation of JAK/STAT pathway by the angiotensin II AT1 receptor. Nature. 1995;375:247-250.
30. Bertrand B, Wakabayashi S, Ikeda T, Pouysségur J, Shigekawa M. The Na+/H+ exchanger isoform 1 (NHE1) is a novel member of the calmodulin-binding proteins: identification and characterization of calmodulin-binding sites. J Biol Chem. 1994;269:13703-13709.
31. 2+ regulation-defective. J Biol Chem. 1994;269:13710-13715.
32. Little PJ, Weissberg PL, Cragoe EJ Jr, Bobik A. Dependence of Na+/H+ antiport activation in cultured rat aortic smooth muscle on calmodulin, calcium, and ATP: evidence for the involvement of calmodulin-dependent kinases. J Biol Chem. 1988;263:16780-16786.
33. + exchanger kinase has increased activity in spontaneously hypertensive rat vascular smooth muscle cells. Hypertension. 1997;29:1265-1272.
34. 2+/calmodulin-dependent protein kinase II. Biochem J. 1992;282:139-145.
35. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science. 1995; 270:1326-1331.
36. Yun CH, Oh S, Zizak M, Steplock D, Tsao S, Tse CM, Weinman EJ, Donowitz M. cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein. Proc Natl Acad Sci U S A. 1997;94:3010-3015.
37. Weinman EJ, Steplock D, Wang Y, Shenolikar S. Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na(+)-H+ exchanger. J Clin Invest. 1995;95: 2143-2149.