-
1
-
-
1842486792
-
The spindle checkpoint, aneuploidy, and cancer
-
DOI 10.1038/sj.onc.1207374
-
Bharadwaj R, Yu H (2004) The spindle checkpoint, aneuploidy, and cancer. Oncogene 23:2016-2027. (Pubitemid 38496731)
-
(2004)
Oncogene
, vol.23
, Issue.11 REV. ISS. 1
, pp. 2016-2027
-
-
Bharadwaj, R.1
Yu, H.2
-
2
-
-
58149260746
-
The spindle checkpoint and chromosomal stability
-
Qi W, Yu H (2006) The spindle checkpoint and chromosomal stability. Genome Dynamics 1:116-130.
-
(2006)
Genome Dynamics
, vol.1
, pp. 116-130
-
-
Qi, W.1
Yu, H.2
-
3
-
-
34247333444
-
The spindle-assembly checkpoint in space and time
-
DOI 10.1038/nrm2163, PII NRM2163
-
Musacchio A, Salmon ED (2007) The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol 8:379-393. (Pubitemid 46643240)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.5
, pp. 379-393
-
-
Musacchio, A.1
Salmon, E.D.2
-
4
-
-
0036902234
-
Regulation of APC-Cdc20 by the spindle checkpoint
-
Yu H (2002) Regulation of APC-Cdc20 by the spindle checkpoint. Curr Opin Cell Biol 14:706-714.
-
(2002)
Curr Opin Cell Biol
, vol.14
, pp. 706-714
-
-
Yu, H.1
-
5
-
-
34250799719
-
Cdc20: A WD40 activator for a cell cycle degradation machine
-
Yu H (2007) Cdc20: a WD40 activator for a cell cycle degradation machine. Mol Cell 27:3-16.
-
(2007)
Mol Cell
, vol.27
, pp. 3-16
-
-
Yu, H.1
-
6
-
-
33747589184
-
The anaphase promoting complex/cyclosome: A machine designed to destroy
-
Peters JM (2006) The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat Rev Mol Cell Biol 7:644-656.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 644-656
-
-
Peters, J.M.1
-
7
-
-
0037183886
-
Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2
-
Martin-Lluesma S, Stucke VM, Nigg EA (2002) Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2. Science 297:2267-2270.
-
(2002)
Science
, vol.297
, pp. 2267-2270
-
-
Martin-Lluesma, S.1
Stucke, V.M.2
Nigg, E.A.3
-
8
-
-
1842529261
-
Identification of Two Novel Components of the Human NDC80 Kinetochore Complex
-
DOI 10.1074/jbc.M310224200
-
Bharadwaj R, Qi W, Yu H (2004) Identification of two novel components of the human NDC80 kinetochore complex. J Biol Chem 279:13076-13085. (Pubitemid 38445885)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.13
, pp. 13076-13085
-
-
Bharadwaj, R.1
Qi, W.2
Yu, H.3
-
9
-
-
0036161468
-
The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20
-
DOI 10.1016/S1097-2765(01)00435-X
-
Luo X, Tang Z, Rizo J, Yu H (2002) The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. Mol Cell 9:59-71. (Pubitemid 34127771)
-
(2002)
Molecular Cell
, vol.9
, Issue.1
, pp. 59-71
-
-
Luo, X.1
Tang, Z.2
Rizo, J.3
Yu, H.4
-
10
-
-
1842420626
-
The Mad2 spindle checkpoint protein has two distinct natively folded states
-
DOI 10.1038/nsmb748
-
Luo X, et al. (2004) The Mad2 spindle checkpoint protein has two distinct natively folded states. Nat Struct Mol Biol 11:338-345. (Pubitemid 38436798)
-
(2004)
Nature Structural and Molecular Biology
, vol.11
, Issue.4
, pp. 338-345
-
-
Luo, X.1
Tang, Z.2
Xia, G.3
Wassmann, K.4
Matsumoto, T.5
Rizo, J.6
Yu, H.7
-
11
-
-
0037093326
-
Crystal structure of the tetrameric Mad1-Mad2 core complex: Implications of a 'safety belt' binding mechanism for the spindle checkpoint
-
DOI 10.1093/emboj/21.10.2496
-
Sironi L, et al. (2002) Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint. EMBO J 21:2496-2506. (Pubitemid 34546721)
-
(2002)
EMBO Journal
, vol.21
, Issue.10
, pp. 2496-2506
-
-
Sironi, L.1
Mapelli, M.2
Knapp, S.3
De Antoni, A.4
Jeang, K.-T.5
Musacchio, A.6
-
12
-
-
36049044125
-
The Mad2 Conformational Dimer: Structure and Implications for the Spindle Assembly Checkpoint
-
DOI 10.1016/j.cell.2007.08.049, PII S0092867407012007
-
Mapelli M, Massimiliano L, Santaguida S, Musacchio A (2007) The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint. Cell 131:730-743. (Pubitemid 350087197)
-
(2007)
Cell
, vol.131
, Issue.4
, pp. 730-743
-
-
Mapelli, M.1
Massimiliano, L.2
Santaguida, S.3
Musacchio, A.4
-
13
-
-
41749098779
-
Insights into mad2 regulation in the spindle checkpoint revealed by the crystal structure of the symmetric mad2 dimer
-
Yang M, et al. (2008) Insights into mad2 regulation in the spindle checkpoint revealed by the crystal structure of the symmetric mad2 dimer. PLoS Biol 6:e50.
-
(2008)
PLoS Biol
, vol.6
-
-
Yang, M.1
-
14
-
-
13444288299
-
The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint
-
DOI 10.1016/j.cub.2005.01.038
-
De Antoni A, et al. (2005) The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint. Curr Biol 15:214-225. (Pubitemid 40205701)
-
(2005)
Current Biology
, vol.15
, Issue.3
, pp. 214-225
-
-
De Antoni, A.1
Pearson, C.G.2
Cimini, D.3
Canman, J.C.4
Sala, V.5
Nezi, L.6
Mapelli, M.7
Sironi, L.8
Faretta, M.9
Salmon, E.D.10
Musacchio, A.11
-
15
-
-
55249120526
-
Protein metamorphosis: The two-state behavior of Mad2
-
Luo X, Yu H (2008) Protein metamorphosis: the two-state behavior of Mad2. Structure 16:1616-1625.
-
(2008)
Structure
, vol.16
, pp. 1616-1625
-
-
Luo, X.1
Yu, H.2
-
16
-
-
36549050792
-
MAD contortions: conformational dimerization boosts spindle checkpoint signaling
-
DOI 10.1016/j.sbi.2007.08.011, PII S0959440X07001182, Catalysis and Regulation /Protein
-
Mapelli M, Musacchio A (2007) MAD contortions: conformational dimerization boosts spindle checkpoint signaling. Curr Opin Struct Biol 17:716-725. (Pubitemid 350186099)
-
(2007)
Current Opinion in Structural Biology
, vol.17
, Issue.6
, pp. 716-725
-
-
Mapelli, M.1
Musacchio, A.2
-
17
-
-
58149466576
-
Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding
-
Kulukian A, Han JS, Cleveland DW (2009) Unattached kinetochores catalyze production of an anaphase inhibitor that requires a Mad2 template to prime Cdc20 for BubR1 binding. Dev Cell 16:105-117.
-
(2009)
Dev Cell
, vol.16
, pp. 105-117
-
-
Kulukian, A.1
Han, J.S.2
Cleveland, D.W.3
-
18
-
-
22144452918
-
The C-terminal half of Saccharomyces cerevisiae Mad1p mediates spindle checkpoint function, chromosome transmission fidelity and CEN Association
-
DOI 10.1534/genetics.105.041426
-
Kastenmayer JP, Lee MS, Hong AL, Spencer FA, Basrai MA (2005) The C-terminal half of Saccharomyces cerevisiae Mad1p mediates spindle checkpoint function, chromosome transmission fidelity and CEN association. Genetics 170:509-517. (Pubitemid 40980655)
-
(2005)
Genetics
, vol.170
, Issue.2
, pp. 509-517
-
-
Kastenmayer, J.P.1
Lee, M.S.2
Hong, A.L.3
Spencer, F.A.4
Basrai, M.A.5
-
19
-
-
0035999976
-
Spindle checkpoint requires Mad1-bound and Mad1-free Mad2
-
DOI 10.1091/mbc.02-01-0003
-
Chung E, Chen RH (2002) Spindle checkpoint requires Mad1-bound and Mad1-free Mad2. Mol Biol Cell 13:1501-1511. (Pubitemid 34522634)
-
(2002)
Molecular Biology of the Cell
, vol.13
, Issue.5
, pp. 1501-1511
-
-
Chung, E.1
Chen, R.-H.2
-
20
-
-
58149093244
-
Requirements for protein phosphorylation and the kinase activity of polo-like kinase 1 (Plk1) for the kinetochore function of mitotic arrest deficiency protein 1 (Mad1)
-
Chi YH, et al. (2008) Requirements for protein phosphorylation and the kinase activity of polo-like kinase 1 (Plk1) for the kinetochore function of mitotic arrest deficiency protein 1 (Mad1). J Biol Chem 283:35834-35844.
-
(2008)
J Biol Chem
, vol.283
, pp. 35834-35844
-
-
Chi, Y.H.1
-
21
-
-
0034214405
-
Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function
-
DOI 10.1016/S0960-9822(00)00515-7
-
Brady DM, Hardwick KG (2000) Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function. Curr Biol 10:675-678. (Pubitemid 30354705)
-
(2000)
Current Biology
, vol.10
, Issue.11
, pp. 675-678
-
-
Brady, D.M.1
Hardwick, K.G.2
-
22
-
-
33744798200
-
Structure of a Central Component of the Yeast Kinetochore: The Spc24p/Spc25p Globular Domain
-
DOI 10.1016/j.str.2006.04.007, PII S0969212606002231
-
Wei RR, et al. (2006) Structure of a central component of the yeast kinetochore: the Spc24p/Spc25p globular domain. Structure 14:1003-1009. (Pubitemid 43831664)
-
(2006)
Structure
, vol.14
, Issue.6
, pp. 1003-1009
-
-
Wei, R.R.1
Schnell, J.R.2
Larsen, N.A.3
Sorger, P.K.4
Chou, J.J.5
Harrison, S.C.6
-
23
-
-
43049146221
-
Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex
-
DOI 10.1016/j.cell.2008.03.020, PII S0092867408004017
-
Ciferri C, et al. (2008) Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex. Cell 133:427-439. (Pubitemid 351622013)
-
(2008)
Cell
, vol.133
, Issue.3
, pp. 427-439
-
-
Ciferri, C.1
Pasqualato, S.2
Screpanti, E.3
Varetti, G.4
Santaguida, S.5
Dos, R.G.6
Maiolica, A.7
Polka, J.8
De Luca, J.G.9
De Wulf, P.10
Salek, M.11
Rappsilber, J.12
Moores, C.A.13
Salmon, E.D.14
Musacchio, A.15
-
24
-
-
77955636058
-
The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments
-
Corbett KD, et al. (2010) The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments. Cell 142:556-567.
-
(2010)
Cell
, vol.142
, pp. 556-567
-
-
Corbett, K.D.1
-
25
-
-
3342991427
-
Solution structure of the RWD domain of the mouse GCN2 protein
-
DOI 10.1110/ps.04751804
-
Nameki N, et al. (2004) Solution structure of the RWD domain of the mouse GCN2 protein. Protein Sci 13:2089-2100. (Pubitemid 38989613)
-
(2004)
Protein Science
, vol.13
, Issue.8
, pp. 2089-2100
-
-
Nameki, N.1
Yoneyama, M.2
Koshiba, S.3
Tochio, N.4
Inoue, M.5
Seki, E.6
Matsuda, T.7
Tomo, Y.8
Harada, T.9
Saito, K.10
Kobayashi, N.11
Yabuki, T.12
Aoki, M.13
Nunokawa, E.14
Matsuda, N.15
Sakagami, N.16
Terada, T.17
Shirouzu, M.18
Yoshida, M.19
Hirota, H.20
Osanai, T.21
Tanaka, A.22
Arakawa, T.23
Carninci, P.24
Kawai, J.25
Hayashizaki, Y.26
Kinoshita, K.27
Guntert, P.28
Kigawa, T.29
Yokoyama, S.30
more..
-
26
-
-
42649124278
-
Anatomy of the E2 ligase fold: Implications for enzymology and evolution of ubiquitin/Ub-like protein conjugation
-
Burroughs AM, Jaffee M, Iyer LM, Aravind L (2008) Anatomy of the E2 ligase fold: implications for enzymology and evolution of ubiquitin/Ub-like protein conjugation. J Struct Biol 162:205-218.
-
(2008)
J Struct Biol
, vol.162
, pp. 205-218
-
-
Burroughs, A.M.1
Jaffee, M.2
Iyer, L.M.3
Aravind, L.4
-
27
-
-
77956378429
-
The MIS12 complex is a protein interaction hub for outer kinetochore assembly
-
Petrovic A, et al. (2010) The MIS12 complex is a protein interaction hub for outer kinetochore assembly. J Cell Biol 190:835-852.
-
(2010)
J Cell Biol
, vol.190
, pp. 835-852
-
-
Petrovic, A.1
-
28
-
-
66349124679
-
Bub1 regulates chromosome segregation in a kinetochore-independent manner
-
Klebig C, Korinth D, Meraldi P (2009) Bub1 regulates chromosome segregation in a kinetochore-independent manner. J Cell Biol 185:841-858.
-
(2009)
J Cell Biol
, vol.185
, pp. 841-858
-
-
Klebig, C.1
Korinth, D.2
Meraldi, P.3
-
29
-
-
33749569228
-
Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells
-
DOI 10.1083/jcb.200606020
-
Liu ST, Rattner JB, Jablonski SA, Yen TJ (2006) Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells. J Cell Biol 175:41-53. (Pubitemid 44537197)
-
(2006)
Journal of Cell Biology
, vol.175
, Issue.1
, pp. 41-53
-
-
Liu, S.-T.1
Rattner, J.B.2
Jablonski, S.A.3
Yen, T.J.4
-
30
-
-
33751232957
-
The Conserved KMN Network Constitutes the Core Microtubule-Binding Site of the Kinetochore
-
DOI 10.1016/j.cell.2006.09.039, PII S0092867406013456
-
Cheeseman IM, Chappie JS, Wilson-Kubalek EM, Desai A (2006) The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell 127:983-997. (Pubitemid 44792248)
-
(2006)
Cell
, vol.127
, Issue.5
, pp. 983-997
-
-
Cheeseman, I.M.1
Chappie, J.S.2
Wilson-Kubalek, E.M.3
Desai, A.4
-
31
-
-
33645730743
-
The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation
-
Kline SL, Cheeseman IM, Hori T, Fukagawa T, Desai A (2006) The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. J Cell Biol 173:9-17.
-
(2006)
J Cell Biol
, vol.173
, pp. 9-17
-
-
Kline, S.L.1
Cheeseman, I.M.2
Hori, T.3
Fukagawa, T.4
Desai, A.5
-
33
-
-
0030687987
-
Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage
-
Taylor SS, McKeon F (1997) Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage. Cell 89:727-735. (Pubitemid 27516175)
-
(1997)
Cell
, vol.89
, Issue.5
, pp. 727-735
-
-
Taylor, S.S.1
McKeon, F.2
-
34
-
-
35649019314
-
Human Blinkin/AF15q14 Is Required for Chromosome Alignment and the Mitotic Checkpoint through Direct Interaction with Bub1 and BubR1
-
DOI 10.1016/j.devcel.2007.09.005, PII S1534580707003462
-
Kiyomitsu T, Obuse C, Yanagida M (2007) Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1. Dev Cell 13:663-676. (Pubitemid 350019284)
-
(2007)
Developmental Cell
, vol.13
, Issue.5
, pp. 663-676
-
-
Kiyomitsu, T.1
Obuse, C.2
Yanagida, M.3
-
35
-
-
4544232810
-
Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1
-
DOI 10.1007/s00412-004-0288-2
-
Stucke VM, Baumann C, Nigg EA (2004) Kinetochore localization and microtubule interaction of the human spindle checkpoint kinase Mps1. Chromosoma 113:1-15. (Pubitemid 39236717)
-
(2004)
Chromosoma
, vol.113
, Issue.1
, pp. 1-15
-
-
Stucke, V.M.1
Baumann, C.2
Nigg, E.A.3
-
36
-
-
0027439390
-
Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin
-
DOI 10.1006/jmbi.1993.1012
-
Van Duyne GD, Standaert RF, Karplus PA, Schreiber SL, Clardy J (1993) Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin. J Mol Biol 229:105-124. (Pubitemid 23037917)
-
(1993)
Journal of Molecular Biology
, vol.229
, Issue.1
, pp. 105-124
-
-
Van Duyne, G.D.1
Standaert, R.F.2
Karplus, P.A.3
Schreiber, S.L.4
Clardy, J.5
-
37
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
DOI 10.1016/S0076-6879(97)76066-X
-
Otwinowski Z, Minor W (1997) Processing X-ray diffraction data collected in oscillation mode. Methods Enzymol 276:307-326. (Pubitemid 27085611)
-
(1997)
Methods in Enzymology
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
38
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
Adams PD, et al. (2010) PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr D 66:213-221.
-
(2010)
Acta Crystallogr D
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
-
40
-
-
74549178560
-
MolProbity: All-atom structure validation for macromolecular crystallography
-
Chen VB, et al. (2010) MolProbity: all-atom structure validation for macromolecular crystallography. Acta Crystallogr D 66:12-21.
-
(2010)
Acta Crystallogr D
, vol.66
, pp. 12-21
-
-
Chen, V.B.1
|