Pharmacological evaluation of [123I]-CLINDE: A radioiodinated imidazopyridine-3-acetamide for the study of peripheral benzodiazepine binding sites (PBBS)

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 35, Issue 4, 2008, Pages 779-789

  Mattner, Filomena ^a   Mardon, Karine ^b   Katsifis, Andrew ^a  

^a AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Imidazopyridines; Iodine 123; Peripheral benzodiazepine binding sites; SPECT

Indexed keywords

4' CHLORODIAZEPAM; ACETAMIDE DERIVATIVE; BENZODIAZEPINE; DRUG METABOLITE; FLUMAZENIL; IODINE 123; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; N',N' DIETHYL 6 CHLORO (4' IODOPHENYL)IMIDAZO[1,2 A]PYRIDINE 3 ACETAMIDE; N',N' DIETHYL 6 CHLORO (4' IODOPHENYL)IMIDAZO[1,2 A]PYRIDINE 3 ACETAMIDE I 123; PROTEIN; PYRIMIDINE DERIVATIVE; RADIOPHARMACEUTICAL AGENT; TRACER; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID A RECEPTOR; 6 CHLORO 2 (4' IODOPHENYL) 3 (N,N DIETHYL)IMIDAZO(1,2 A)PYRIDINE 3 ACETAMIDE; 6-CHLORO-2-(4'-IODOPHENYL)-3-(N,N-DIETHYL)IMIDAZO(1,2-A)PYRIDINE-3-ACETAMIDE; BENZODIAZEPINE DERIVATIVE; FUSED HETEROCYCLIC RINGS; RADIOACTIVE IODINE;

ADRENAL CORTEX; ANIMAL EXPERIMENT; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BINDING SITE; BLOOD; BRAIN CORTEX; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DRUG BINDING; DRUG DISTRIBUTION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; HEART; HOMOGENATE; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; KIDNEY HOMOGENATE; LIPOPHILICITY; LUNG; MALE; MITOCHONDRIAL MEMBRANE; NONHUMAN; OLFACTORY BULB; RADIOACTIVITY; RADIOIODINATION; RAT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SPRAGUE DAWLEY RAT; ADRENAL GLAND; ANIMAL; INTRACELLULAR MEMBRANE; KIDNEY; KINETICS; METABOLISM; MITOCHONDRION; SCINTISCANNING; TISSUE DISTRIBUTION;

ADRENAL GLANDS; ANIMALS; BENZODIAZEPINES; BICYCLO COMPOUNDS, HETEROCYCLIC; BINDING SITES; CEREBRAL CORTEX; INTRACELLULAR MEMBRANES; IODINE RADIOISOTOPES; KIDNEY; KINETICS; MALE; MITOCHONDRIA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; TISSUE DISTRIBUTION;

EID: 40949121111     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-007-0645-5     Document Type: Article

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