Interplay between mechanisms of damage and repair in multiple sclerosis

Journal of Neurology

Volumn 255, Issue SUPPL. 1, 2008, Pages 12-18

  Stadelmann, Christine ^a   Brück, Wolfgang ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Axonal damage; Demyelination; Inflammation; Multiple sclerosis; Neuropathology; Remyelination

Indexed keywords

AXONAL INJURY; B LYMPHOCYTE; CONFERENCE PAPER; DISEASE COURSE; HISTOPATHOLOGY; HUMAN; MULTIPLE SCLEROSIS; MYELIN SHEATH; NERVE FIBER DEGENERATION; PRIORITY JOURNAL; REMYELINIZATION; T LYMPHOCYTE ACTIVATION; TISSUE REPAIR; WHITE MATTER;

ANIMALS; BRAIN; DEMYELINATING DISEASES; DISEASE PROGRESSION; HUMANS; MULTIPLE SCLEROSIS; MYELIN PROTEINS;

EID: 40349115902     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-008-1003-7     Document Type: Conference Paper

References (7)

1. Albert M, Antel J, Bruck W, Stadelmann C (2007) Extensive cortical remyelination in patients with chronic multiple sclerosis. Brain Pathology (Zurich, Switzerland) 17:129-138
2. Barkhof F, Bruck W, De Groot CJ, Bergers E, Hulshof S, Geurts J, Polman CH, van der Valk P (2003) Remyelinated lesions in multiple sclerosis: magnetic resonance image appearance. Arch Neurol 60:1073-1081
3. Bitsch A, Schuchardt J, Bunkowski S, Kuhlmann T, Bruck W (2000) Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation. Brain 123(Pt 6):1174-1183
4. Kuhlmann T, Lingfeld G, Bitsch A, Schuchardt J, Bruck W (2002) Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time. Brain 125:2202-2212
5. Kutzelnigg A, Lucchinetti CF, Stadelmann C, Bruck W, Rauschka H, Bergmann M, Schmidbauer M, Parisi JE, Lassmann H (2005) Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain 128:2705-2712
6. Magliozzi R, Howell O, Vora A, Serafini B, Nicholas R, Puopolo M, Reynolds R, Aloisi F (2007) Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. Brain 130:1089-1104
7. Patrikios P, Stadelmann C, Kutzelnigg A, Rauschka H, Schmidbauer M, Laursen H, Sorensen PS, Bruck W, Lucchinetti C, Lassmann H (2006) Remyelination is extensive in a subset of multiple sclerosis patients. Brain 129:3165-3172