Osteoblasts induce osteopontin expression in response to attachment on fibronectin: Demonstration of a common role for integrin receptors in the signal transduction processes of cell attachment and mechanical stimulation

Journal of Cellular Biochemistry

Volumn 70, Issue 3, 1998, Pages 376-390

  Carvalho, R S ^a,b   Schaffer, J L ^c   Gerstenfeld, L C ^a,d  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d BOSTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Integrins; Mechano transduction; Osteopontin; Tyrosine kinase

Indexed keywords

BOMBESIN; FIBRONECTIN; INTEGRIN; LYSOPHOSPHATIDIC ACID; MESSENGER RNA; OSTEOPONTIN; PROTEIN TYROSINE KINASE; RECEPTOR;

ANIMAL CELL; ARTICLE; CELL ADHESION; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; MECHANICAL STIMULATION; MICROFILAMENT; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

ANIMALS; BINDING, COMPETITIVE; BOMBESIN; CELL ADHESION; CHICK EMBRYO; COLCHICINE; CYCLOHEXIMIDE; CYTOCHALASIN D; FIBRONECTINS; GENE EXPRESSION REGULATION; GENISTEIN; INTEGRINS; LYSOPHOSPHOLIPIDS; OLIGOPEPTIDES; OSTEOBLASTS; OSTEOPONTIN; RNA, MESSENGER; SIALOGLYCOPROTEINS; SIGNAL TRANSDUCTION;

ANIMALIA; GALLUS GALLUS;

EID: 0031904354     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19980901)70:3<376::AID-JCB11>3.0.CO;2-J     Document Type: Article

References (72)

1. Aarden EM, Nijweide PJ, van der Plas A, Alblas MJ, Mackie EJ, Horton MA, Helfrich MH (1996): Adhesive properties of isolated chick osteocytes in vitro. Bone 18:305-313.
2. Barbee KA, Macarak EJ, Thibault LE (1994): Strain measurements in cultured vascular smooth muscle cells subjected to mechanical deformation. Ann Biomed Eng 22: 14-22.
3. Bereford, GW, Agius L (1994): Cytochalasin-D exerts stimulatory and inhibitory effects on insulin-induced glucokinase mRNA expression in hepatocytes. Mol Cell Biochem 139:177-184.
4. Brighton CT, Stratfford B, Gross SB, Leatherwood DF, Williams JL, Pollack SR (1991): The proliferative and synthetic response of isolated calvarial bone cells of rats to cyclic biaxial mechanical strain. J Bone Joint Surg 73:320-331.
5. Butler WT (1989): The nature and significance of osteopontin. Conn Tiss Res 23:123-136.
6. Carvalho RS, Scott JE, Suga DM, Yen EHK (1993): Stimulation of signal transduction in osteoblasts by mechanical strain potentiated by parathyroid hormone. J Bone Miner Res 9:999-1011.
7. Chen WT, Chen JM, Muller SC (1986): Coupled expression and colocalization of 140K cell adhesion molecules, fibronectin and laminin during morphogenesis and cytodifferentiation of chick lung cells. J Cell Biol 103:1073-1090.
8. Clark EA, Brugge JS (1995): Integrins and signal transduction pathways: the road taken. Science 268:233-239.
9. Clover J, Dodds RA, Gowen M (1992): Integrin subunit expression by human osteoblasts and osteoclasts in situ and in culture. J Cell Sci 103:267-271.
10. Curtis ASG (1987): Cell activations and adhesion. J Cell Sci 87:609-611.
11. Curtis ASG, McGrath M, Gasmi L (1992): Localized application of an activating signal to a cell: Experimental use of fibronectin bound beads and the implications for mechanisms of adhesion. J Cell Sci 101:427-436.
12. Flores ME, Norgard M, Heinegard D, Reinholt FP, Anderson G (1992): RGD-directed attachment of isolated rat osteoclasts to osteopontin, bone sialoprotein and fibronectin. Exp Cell Res 201:526-530.
13. Gerstenfeld LC, Chipman S, Kelly C, Lee DD, Landis WJ (1988): Collagen expression, ultrastructural assembly and mineralization in cultures of chicken embryo osteoblasts. J Cell Biol 106:979-989.
14. Gerstenfeld LC, Gotoh Y, Mckee MD, Nanci A, Landis WJ, Glimcher MJ (1990): Expression and ultrastructural localization of the major phosphoprotein synthesized by chicken osteoblasts during in vitro mineralization. Anat Rec 228:93-103.
15. Gerstenfeld LC, Uporova T, Ashkar S, Salih E, Gerstenfeld LC, Glimcher MJ ( 1995): Regulation of avian osteopontin pre-and post translational expression in skeletal tissues. Ann NY Acad Sci 270:67-82.
16. Ginsberg MH, Du X, Plow EF (1992): Inside-out integrin signaling. Curr Opin Cell Biol 4:766-771.
17. Gotoh Y, Gerstenfeld LC, Glimcher MJ (1990): Identification and characterization of the major chicken bone phosphoprotein. Analysis of its synthesis by cultured embryonic chick osteoblasts. Eur J Biochem 187:49-58.
18. Grzesik W, Robey PG (1994): Bone matrix RGD glycoproteins: Immunolocalization and interaction with primary osteoblastic bone cells in vitro. J Bone Miner Res 9:487-496.
19. Guan JL, Trevithick JE, Hynes RO (1991): Fibronectin/ integrin interaction induces tyrosine phosphorylation of a 120 kDa protein. Cell Reg 2:951-964.
20. Guo X, Zhang YP, Mitchell DA, Denhardt DA, Chambers AF (1994): Identification of a ras-activated enhancer in the mouse osteopontin promoter and its interaction with a putative ETS-related transcription factor whose activity correlates with metastatic potential. Mol Cell Biol 15:476-487.
21. Harter LV, Hruska KA, Duncan RL (1995): Human osteoblast-like cells respond to mechanical strain with increased bone matrix protein production independent of hormonal regulation. Endocrinology 136:528-535.
22. Hynes RO (1992): Integrins: Versatility, modulation, and signaling in cell adehesion. Cell 69:11-25.
23. Ingber DE (1991): Integrins as mechanochemical transducers. Curr Opin Cell Biol 3:841-848.
24. Ingber DE (1992): Extracellular matrix as a solid-state regulator in angiogenesis: identification of new targets for anti-cancer therapy. Sem Cancer Biol 3:57-63.
25. Ingber DE (1994): Cellular tensegrity: Exploring how mechanical changes in the cytoskeleton regulate cell growth, migration, and tissue patterning during morphogenisis. Int Rev Cytol 150:173-224.
26. Juliano RL, Haskill S (1993): Signal transduction from the extracellular matrix. J Cell Biol 120:77-585.
27. Kornberg L, Earp HS, Turner C, Procop C, Juliano RL (1991): Signal transduction by integrins: increased protein tyroine kinase phosphorylation caused by clustering of beta 1 integrins. Proc Nat Acad Sci USA 88:8392-8396.
28. Kubota TM, Yamauchi M, Onozaki SS, Suzuki Y, Sodek J (1993): Influence of an intermittent compressive force on matrix expression by ROS 17/2.8 cells with selective stimulation of osteopontin. Archs Oral Biol 38:23-30.
29. Lanyon LE (1984): Functional strain as a determinant of bone remodelling. Calcif Tissue Int 36 (Suppl 1):S56-S61.
30. Lanyon LE, Rubin CT (1987): Functional strain on bone tissue as an objective and controlling stimulus for adaptive bone remodeling. J Biomech 15:141-154.
31. Liaw L, Skinner MP, Raines EW, Ross R, Cheresh DA, Schwartz SM, Giachelli CM (1995): The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. J Clin Invest 95:713-724.
32. Loeser RF (1993): Integrin-mediated attachment of articular chondrocytes to extracellular matrix proteins. Arthritis Rheum 36:1103-1110.
33. Majda JA, Gerner EW, Vanlandingham B, Gehlsen, KR, Cress AE (1994): Heat schock-induced shedding of cell surface integrins in A549 human lung tumor cells in culture. Exp Cell Res 210:46-51.
34. McAllister BS, Walters JD, Olson MS (1994): Signal transduction mechanisms in mesenchymal cells. Cri Rev Oral Biol 5:291-310.
35. McKee M, Nanci A, Landis WJ, Gotoh Y, Gerstenfeld LC, Glimcher MJ (1990): Developmental appearance and ultrastructural immunolocalization of a major 66 KDa phosphoprotein in embryonic and post-natal chicken. Anat Rec 228:77-92.
36. McLeod KJ, Lee RC, Ehrlich HP (1987): Frequency dependence of electric field modulation of fibroblast protein synthesis. Science 236:1465-1469.
37. Milam SB, Magnuson VL, Steffensen B, Chen D, Klebe RJ (1991): IL-1b and prostaglandins regulate integrin mRNA expression. J Cell Physiol 149:173-183.
38. Miyamoto S, Akiyama SK, Yamada KM (1995): Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science 267:883-897.
39. Miyauchi AJ, Alvarez JI, Greenfield EM, Teti A, Grano M, Colucci S, Zambonin-Allone A, Ross FP, Teitelbaum SM, Cheresh D, Hruska KA (1991): Recognition of osteopontin and related peptides by an avb3 integrin stimulates immediate cell signals in osteoclasts. J Biol Chem 266: 20369-20374.
40. Moore MA, Gotoh Y, Rafidi K, Gerstenfeld LC (1991): Characterization of a cDNA for chicken osteopontin: Expression during bone development, osteoblast differentiation and tissue distribution. Biochemistry 30:2501-2508.
41. Morita T, Kurihara H, Maemura K, Yoshizumi M, Yazaki Y (1993): Disruption of cytoskeletal structures mediates shear stress-induced endothelin-1 gene expression in cultured porcine aortic endothelial cells. J Clin Invest 92: 1706-1712.
42. Mueller SC, Kelly T, Dai M, Dai H, Chen W (1989): Dynamic cytoskeleton-integrin associations induced by cell binding to immobilized fibronection. J Cell Biol 109:3455-3464.
43. Nomura A, Wills AJ, Edwards DR, Health JK, Hogan BL (1988): Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization. J Cell Biol 106:441-450.
44. Oldberg A, Franzen A, Heinegard D, Pierschbacher M, Ruoslahti E (1988): Identification of a one sialoprotein receptor in osteosarcoma cells. J Biol Chem 263:19433-19436.
45. Patarca R, Freeman GJ, Sing RP, Wei FY, Durfee T, Blattner C, Regnier DC, Kozak CA, Mock BA, Morese HC III, Jerrells TR, Cantor H (1989): Structural functional studies of the early T lymphocyte activation (Eta-1) gene. J Exp Med 170:145-162.
46. Pizzey JA, Jones GE, Walsh FS (1989): Requirements for the Ca2+-independent component in the initial intercellular adhesionof C2 myoblasts. J Cell Biol 107:2307-2317.
47. Puleo DA, Bizios R (1992): Mechanisms of fibronectin-mediated attachment of osteoblasts to substrates in vitro. Bone Min 18:215-226.
48. Raab-Cullen DM, Petersen DN, Thiede MA (1995): Effects of multiple mechanical loading sessions on periosteal gene expression. J Bone Miner Res 10:255S.
49. Rafidi K, Simkina I, Johnson E, Moore MA, Gerstenfeld LC (1994): Characterization of the structural and regulatory sequences of the chicken osteopontin gene. Gene 140:163-169.
50. Ridley A, Hall A (1994) Signal transduction pathways regulating Rho-mediated stress fiber formation: Requirement of a tyrosin kinase. EMBO J 13:2600-2610.
51. Ross, FP, Chappel J, Alvarez JI, Sander D, Butler WT, Farach-Carson MC, Mintz KA, Robey PG, Teitelbaum SL, Cheresh DA (1993): Interaction between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin alpha v beta 3 potentiate bone resorption. J Biol Chem 5:9901-9907.
52. Rubin CT, Lanyon LE (1985): Regulation of bone mass by mechanical strain magnitude. Calcif Tiss Int 37:411-417.
53. Rubin, CT, McLeod KJ, Lanyon LE (1989): Prevention of osteoporosis by pulse electromagnetic fields. J Bone Joint Surg 71:411-417.
54. 32P-labeled osteopontin from cultured chicken osteoblasts. J Biol Chem 272:19966-13973.
55. Sandy JR, Meghji S, Farndale RW, Meike MC (1989): Dual elevation of cyclic AMP and inositol phosphates in response to mechanical deformation of murine osteoblasts. Biochim Biophys Acta 1010:265-926.
56. Sastry SK, Horwitz AF (1993): Integrin cytoplasmic domains: Mediators of cytoskeletal linkages and extra-and intracellular initiated transmembrane signaling. Curr Opin Cell Biol 5:819-831.
57. Schaffer JL, Rizen M, L'Italien GJ, Megerman J, Gerstenfeld LC, Gray ML (1994): ADevice for the Application of a Dynamic Biaxially Uniform and Isotropic Strain to a Flexible Cell Culture Membrane. J Orthop Res 12:709-719.
58. Schaller MD, Parsons JD (1994): Focal adhesion kinase and associated proteins. Curr Opin Cell Biol 6:705-710.
59. Schneider G, Burridge K (1994): Fibronectin gene expression, synthesis and accumulation during in vitro differentiation of chicken osteoblasts. J Bone Miner Res 10:1969-1977.
60. Schwartz MA (1993): Signaling by integrins: Implications for tumorigenesis. Cancer Res 53:1503-1506.
61. Senger DR, Perruzzi CA, Papadopoulos A (1989): Elevated expression of secreted phosphoprotein 1 (osteopontin, 2ar) as a consequence of neoplastic transformation. Anticancer Res 9:1291-1300.
62. Singh RP, Patarca R, Schwartz J, Singh P, Cantor H (1991): Definition of a specific interaction between the early T lymphocyte activation 1 (Eta-1) protein and murine macrophages in vitro and its effect upon macrophages in vivo. J Exp Med 171:1931-1942.
63. Smith JH, Denhardt DT (1987): Molecular cloning of a tumor promoter-inducible mRNA found in JB6 mouse epidermal cells: Induction is stable at high, but not at low, cell densities. J Cell Biochem 34:13-22.
64. Somerman MJ, Prince CW, Sauk JJ, Foster RA, Butler WT (1987): Mechanism of fibroblast attachment to bone extracellular matrix: role of a 44 kilodalton bone phosphoprotein. J Bone Miner Res 2:259-265.
65. Tezuka K, Sato T, Kamioka H, Nijweide PT, Tanaka K, Matsuo T, Ohta M, Kurihara N, Hakeda Y, Kumegawa M (1992): Identification of osteopontin in isolated rabbit osteoclasts. Biochem Biophys Res Comm 186:911-911.
66. Toma CD, Ashkar S, Gray ML, Schaffer JL, Gerstenfeld LC (1997): Mechano-induction of osteopontin expression in osteoblasts: Dependency of signal transduction on microfilanment integrity. J Bone Miner Res 12:1626-1636.
67. Watson PA (1991): Function follows form: generation of intracellular signals by cell deformation. FASEB J 5:2013-2019.
68. Weber GF, Ashkar S. Glimcher MJ, Cantor H (1996): Receptor-ligand interaction between CD44 and osteopontin (Eta-1). Science 271:509-512.
69. Werb Z, Tremble PM, Behrendtsen O, Crowley E, Damsky CH (1989): Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J Cell Biol 109:877-889.
70. Wilson E, Sudhir K, Ives HE (1996): Mechanical strain of rat smooth muscle cells is sensed by specific extracellular matrix/integrin interactions. J Clin Inv 96:2364-2372.
71. Xuan JW, Hota C, Chambers AF (1994): Recombinant GST-human osteopontin in fusion protein is functional in RGD-dependent cell adhesion.J Cell Biochem 54:247-255.
72. Yasuda M, Hasunuma Y, Adachi H, Sekine C, Sakanishi T, Hashimoto H, Ra C, Yagita H, Okumura K (1995): Expression and function of fibronectin binding integrins on rat mast cells. Int Immunol 7:251-258.