The hepatocarcinogenic conazoles: Cyproconazole, epoxiconazole, and propiconazole induce a common set of toxicological and transcriptional responses

Toxicological Sciences

Volumn 127, Issue 1, 2012, Pages 54-65

  Hester, Susan ^a   Moore, Tanya ^a   Padgett, William T ^a   Murphy, Lynea ^a   Wood, Charles E ^a   Nesnow, Stephen ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

All trans retinoic acid; Cell proliferation; Cholesterol; Conazoles; Cyproconazole; Epoxiconazole; Hepatocarcinogenic; Ki67; Liver; Mice; Propiconazole; Transcriptional analyses

Indexed keywords

CARCINOGEN; CHOLESTEROL; CYPROCONAZOLE; CYTOCHROME P450; EPOXICONAZOLE; GLUTATHIONE TRANSFERASE; PROPICONAZOLE; RETINOIC ACID; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; HEPATOMEGALY; LIVER CELL; LIVER CELL CARCINOMA; LIVER HYPERTROPHY; LIVER TOXICITY; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; XENOBIOTIC METABOLISM;

EID: 84860130566     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs086     Document Type: Article

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