-
1
-
-
0037351102
-
Azole fungicides affect mammalian steroidogenesis by inhibiting sterol 14 Sphademethylase and aromatase
-
Zarn, J. A.; Bruschweller, B. J.; Schlatter, J. R. Azole fungicides affect mammalian steroidogenesis by inhibiting sterol 14 Sphademethylase and aromatase. Environ. Health Perspect. 2003, 111, 255-261.
-
(2003)
Environ. Health Perspect.
, vol.111
, pp. 255-261
-
-
Zarn, J.A.1
Bruschweller, B.J.2
Schlatter, J.R.3
-
2
-
-
67649148641
-
Propiconazole part II toxicology
-
INCHEM. Monograph 768
-
INCHEM. Monograph 768. Propiconazole Part II Toxicology. In Pestidde Residues in Food: 1987 Evaluations, 1987; p 19.
-
(1987)
Pestidde Residues in Food: 1987 Evaluations
, pp. 19
-
-
-
4
-
-
33845776093
-
Toxicity profiles in mice treated with hepatotumorigenic and non-hepatotumorigenlc triazole conazole fungicides. Propiconazole, triadlmefon and myclobutanll
-
Allen, J. W.; Wolf, D. C.; George, M. H.; Hester, S. D.; Sun, G.; Thai, S. F.; Delker, D. A.; Moore, T.; Jones, C.; Nelson, G.; Roop, B. C.; Leavitt, S.; Winkfield, E.; Ward, W. O.; Nesnow, S. Toxicity profiles in mice treated with hepatotumorigenic and non-hepatotumorigenlc triazole conazole fungicides. Propiconazole, triadlmefon and myclobutanll. Toxicol. Pathol. 2006, 34, 853-862.
-
(2006)
Toxicol. Pathol.
, vol.34
, pp. 853-862
-
-
Allen, J.W.1
Wolf, D.C.2
George, M.H.3
Hester, S.D.4
Sun, G.5
Thai, S.F.6
Delker, D.A.7
Moore, T.8
Jones, C.9
Nelson, G.10
Roop, B.C.11
Leavitt, S.12
Winkfield, E.13
Ward, W.O.14
Nesnow, S.15
-
5
-
-
58149466220
-
Three conazoles increase hepatic microsomal retinoic acid metabolism and decrease mouse hepatic retinoic acid levels in vivo
-
Chen, P. J.; Padgett, W. T.; Moore, T.; Winnik, W.; Lambert, G. R.; Thai, S. F.; Hester, S. D.; Nesnow, S. Three conazoles increase hepatic microsomal retinoic acid metabolism and decrease mouse hepatic retinoic acid levels in vivo. Toxicol. Appl. Pharmacol. 2009, 234, 143-155.
-
(2009)
Toxicol. Appl. Pharmacol.
, vol.234
, pp. 143-155
-
-
Chen, P.J.1
Padgett, W.T.2
Moore, T.3
Winnik, W.4
Lambert, G.R.5
Thai, S.F.6
Hester, S.D.7
Nesnow, S.8
-
6
-
-
10444274956
-
Propiconazole-induced cytochrome P450 gene expression and enzymatic activities in rat and mouse liver
-
Sun, G.; Thai, S. F.; Tully, D. B.; Lambert, G. R.; Goetz, A. K.; Wolf, D. C.; Dix, D. J.; Nesnow, S. Propiconazole-induced cytochrome P450 gene expression and enzymatic activities in rat and mouse liver. Toxicol. Lett. 2005, 155, 277-287.
-
(2005)
Toxicol. Lett.
, vol.155
, pp. 277-287
-
-
Sun, G.1
Thai, S.F.2
Tully, D.B.3
Lambert, G.R.4
Goetz, A.K.5
Wolf, D.C.6
Dix, D.J.7
Nesnow, S.8
-
7
-
-
33845771203
-
Transcriptional profiles in liver from mice treated with hepatotumorigenic and non-hepatotumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil
-
Ward, W. O.; Delker, D. A; Hester, S. D.; Thai, S. F.; Wolf, D. C.; Allen, J. W.; Nesnow, S. Transcriptional profiles in liver from mice treated with hepatotumorigenic and non-hepatotumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil. Toxicol. Pathol. 2006, 34, 863-878.
-
(2006)
Toxicol. Pathol.
, vol.34
, pp. 863-878
-
-
Ward, W.O.1
Delker, D.A.2
Hester, S.D.3
Thai, S.F.4
Wolf, D.C.5
Allen, J.W.6
Nesnow, S.7
-
8
-
-
67649224671
-
Discrimination of tumorigenic triazole conazoles from phenobarbital by transcriptional analyses of mouse liver gene expression
-
Nesnow, S.; Ward, W.; Moore, T.; Ren, H.; Hester, S. D. Discrimination of tumorigenic triazole conazoles from phenobarbital by transcriptional analyses of mouse liver gene expression. Toxicol. Sci. 2009, 110, 68-83.
-
(2009)
Toxicol. Sci.
, vol.110
, pp. 68-83
-
-
Nesnow, S.1
Ward, W.2
Moore, T.3
Ren, H.4
Hester, S.D.5
-
9
-
-
65249108716
-
Protein carbonyl formation in response to propiconazole-induced oxidative stress
-
Bruno, M.; Moore, T.; Nesnow, S.; Ge, Y. Protein carbonyl formation In response to propiconazole-induced oxidative stress. J. Proteome Res. 2009, 8, 2070-2078.
-
(2009)
J. Proteome Res.
, vol.8
, pp. 2070-2078
-
-
Bruno, M.1
Moore, T.2
Nesnow, S.3
Ge, Y.4
-
10
-
-
61649083757
-
A In vivo mutagenicity of conazole fungicides correlates with tumorlgenicity
-
Ross, J. A.; Moore, T.; Leavitt, S. A In vivo mutagenicity of conazole fungicides correlates with tumorlgenicity. Mutaeenesis 2008, 24, 149-152.
-
(2008)
Mutaeenesis
, vol.24
, pp. 149-152
-
-
Ross, J.A.1
Moore, T.2
Leavitt, S.3
-
11
-
-
0031470895
-
The significance of mouse liver tumor formation for carcinogenic risk assessment: Results and conclusions from a survey of ten years of testing by the agrochemical industry
-
Carmichael, N. G.; Enzmann, H.; Pate, I.; Waechter, F. The significance of mouse liver tumor formation for carcinogenic risk assessment: results and conclusions from a survey of ten years of testing by the agrochemical industry, Environ. Health. Perspect. 1997, 105, 1196-1203.
-
(1997)
Environ. Health. Perspect.
, vol.105
, pp. 1196-1203
-
-
Carmichael, N.G.1
Enzmann, H.2
Pate, I.3
Waechter, F.4
-
12
-
-
0025039794
-
Ethanol-induced phosphorylation of cytokeratin in cultured hepatocytes
-
Kawahara, H.Cadrin, M.; French, S. W. Ethanol-induced phosphorylation of cytokeratin in cultured hepatocytes. Life Sci. 1990, 47, 859-863.
-
(1990)
Life Sci.
, vol.47
, pp. 859-863
-
-
Kawahara, H.1
Cadrin, M.2
French, S.W.3
-
13
-
-
11344292695
-
Genomic and proteomic profiling for biomarkers and signature profiles of toxicity
-
Merrick, B. A.; Bruno, M. E. Genomic and proteomic profiling for biomarkers and signature profiles of toxicity. Curr. Qpin. Mol. Ther. 2004, 6, 600-607.
-
(2004)
Curr. Qpin. Mol. Ther.
, vol.6
, pp. 600-607
-
-
Merrick, B.A.1
Bruno, M.E.2
-
14
-
-
55849147636
-
Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors
-
Pan, C.; Gnad, F.; Olsen, J. V.; Mann, M. Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors. Proteomics 2008, 8, 4534-4546.
-
(2008)
Proteomics
, vol.8
, pp. 4534-4546
-
-
Pan, C.1
Gnad, F.2
Olsen, J.V.3
Mann, M.4
-
15
-
-
33745978798
-
Effects of sodium arsenite on catalase activity, gene and protein expression in HaCaT cells
-
Sun, X.; Li, B.; Li, X.; Wang, Y.; Sun, G. F. Effects of sodium arsenite on catalase activity, gene and protein expression in HaCaT cells. Toxicol. in Vitro 2008, 20, 1139-1144
-
(2008)
Toxicol. in Vitro
, vol.20
, pp. 1139-1144
-
-
Sun, X.1
Li, B.2
Li, X.3
Wang, Y.4
Sun, G.F.5
-
16
-
-
0037146488
-
Highly sensitive and fast protein detection with coomassie brilliant blue in sodium dodecyl sulfate-polyacrylamide gel electrophoresis
-
Kang, D. H.; Gho, Y. S.; Suh, M.; Chulhun Kang, C. Highly Sensitive and Fast Protein Detection with Coomassie Brilliant Blue in Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis. Bull. Korean Chem. Soc. 2002, 23, 1511-1512.
-
(2002)
Bull. Korean Chem. Soc.
, vol.23
, pp. 1511-1512
-
-
Kang, D.H.1
Gho, Y.S.2
Suh, M.3
Chulhun Kang, C.4
-
17
-
-
4444267191
-
Differential expression of the skeletal muscle proteome in mdx mice at different ages
-
Ge, Y.; Molloy, M. P.; ChamberlSn, J. S.; Andrews, P. C. Differential expression of the skeletal muscle proteome in mdx mice at different ages. Electrophoresis 2004, 25, 2576-2585.
-
(2004)
Electrophoresis
, vol.25
, pp. 2576-2585
-
-
Ge, Y.1
Molloy, M.P.2
Chamberlsn, J.S.3
Andrews, P.C.4
-
18
-
-
0026694947
-
In-gel digestion of proteins for internal sequence analysis after one or two-dimensionS gel electrophoresis
-
Rosenfeld, J.; Capdevielle, J.; Guillermot, J. C.; Ferrara, P. In-gel digestion of proteins for internal sequence analysis after one or two-dimensionS gel electrophoresis. Anal. Biochem. 1992, 203, 173-179.
-
(1992)
Anal. Biochem.
, vol.203
, pp. 173-179
-
-
Rosenfeld, J.1
Capdevielle, J.2
Guillermot, J.C.3
Ferrara, P.4
-
19
-
-
4644269948
-
Combination of 'omics' data to investigate the mechanism(s) of hydrazineinduced hepatotoxicity in rats and to identify potential biomarkers
-
Klenø, T. G.; Kiehr, B.; Baunsgaard, D.; Sidelmann, U. G. Combination of 'omics' data to investigate the mechanism(s) of hydrazineinduced hepatotoxicity in rats and to identify potential biomarkers. Biomarkers 2004, 9, 161-1138
-
(2004)
Biomarkers
, vol.9
, pp. 161-1138
-
-
Klenø, T.G.1
Kiehr, B.2
Baunsgaard, D.3
Sidelmann, U.G.4
-
20
-
-
33745823913
-
Systems toxicology: Integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat
-
Craig, A.; Sidaway, J.; Holmes, E.; Orton, T.; Jackson, D.; Rowlinson, R.; Nickson, J.; Tonge, R.; Wilson, I.; Nicholson, J. Systems toxicology: integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat. J Proteome Res. 2006, 7, 1586-1601.
-
(2006)
J Proteome Res.
, vol.7
, pp. 1586-1601
-
-
Craig, A.1
Sidaway, J.2
Holmes, E.3
Orton, T.4
Jackson, D.5
Rowlinson, R.6
Nickson, J.7
Tonge, R.8
Wilson, I.9
Nicholson, J.10
-
21
-
-
20844440723
-
Identification of coexpressed gene clusters in a comparative analysis of transcrlptome and proteome in mouse tissues
-
Mijalski, T.; Harder, A.; Halder, T.; Kersfen, M.; Horsch, M.; Strom, T. M.; Liebscher, H. V.; Lottspeich, F.; de Angelis, M. H. Identification of coexpressed gene clusters in a comparative analysis of transcrlptome and proteome in mouse tissues. Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 8621-8626.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 8621-8626
-
-
Mijalski, T.1
Harder, A.2
Halder, T.3
Kersfen, M.4
Horsch, M.5
Strom, T.M.6
Liebscher, H.V.7
Lottspeich, F.8
De Angelis, M.H.9
-
22
-
-
68549094627
-
Comparative transcriptome and proteome analysis of Ha-ras and B-raf mutated mouse liver tumors
-
Rignall, B.; Ittrich, C.; Krause, E.; Appel, K. E.; Buchmann, A.; Schwarz, M. Comparative transcriptome and proteome analysis of Ha-ras and B-raf mutated mouse liver tumors. J. Proteome Res. 2009, 8 (8), 3987-3994.
-
(2009)
J. Proteome Res.
, vol.8
, Issue.8
, pp. 3987-3994
-
-
Rignall, B.1
Ittrich, C.2
Krause, E.3
Appel, K.E.4
Buchmann, A.5
Schwarz, M.6
-
23
-
-
34250783088
-
Integrative analysis of transcriptomic and proteomic data: Challenges, solutions and applications
-
Nie, L.; Wu, G.; Culley, D. E.; Scholten, J. C.; Zhang, W. Integrative analysis of transcriptomic and proteomic data: challenges, solutions and applications. Crit. Rev. Biotechnol. 2007, 27, 63-75.
-
(2007)
Crit. Rev. Biotechnol.
, vol.27
, pp. 63-75
-
-
Nie, L.1
Wu, G.2
Culley, D.E.3
Scholten, J.C.4
Zhang, W.5
-
24
-
-
0037249505
-
Alteration of glutathione S-transferase levels in Barrett's metaplasia compared to normal oesophageal epithelium
-
Cobbe, S. C.; Scobie, G. C.; Pohler, E.; Hayes, J. D.; Kernohan, N. M.; Dillon, J. F. Alteration of glutathione S-transferase levels in Barrett's metaplasia compared to normal oesophageal epithelium. Eur. J. Gastroenterol. Hepatol. 2003, 15, 41-47.
-
(2003)
Eur. J. Gastroenterol. Hepatol.
, vol.15
, pp. 41-47
-
-
Cobbe, S.C.1
Scobie, G.C.2
Pohler, E.3
Hayes, J.D.4
Kernohan, N.M.5
Dillon, J.F.6
-
25
-
-
0037304032
-
Cancer and phase II drugmetabolizing enzymes
-
Sheweita, S. A.; Tilmisany, A K. Cancer and phase II drugmetabolizing enzymes. Curr. Drug Metab. 2003, 4, 45-58.
-
(2003)
Curr. Drug Metab.
, vol.4
, pp. 45-58
-
-
Sheweita, S.A.1
Tilmisany, A.K.2
-
26
-
-
51349145143
-
Transcription factor and hepatocyte differentiation
-
Nagaki, M.; Moriwaki, H. Transcription factor and hepatocyte differentiation. Hepatol. Res. 2008, 38, 961-969.
-
(2008)
Hepatol. Res.
, vol.38
, pp. 961-969
-
-
Nagaki, M.1
Moriwaki, H.2
-
27
-
-
0027960532
-
Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression
-
Zhong, W.; Mirkovitch, J.; Darnell, J. E., Jr. Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression. Mol. Cell. Biol. 1994, 14, 7276-7284.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 7276-7284
-
-
Zhong, W.1
Mirkovitch, J.2
Darnell Jr., J.E.3
-
28
-
-
0034680936
-
Hepatocyte nuclear factor 4 alpha regulates the expression of pancreatic beta-cell genes implicated in glucose metabolism and nutrient-induced insulin secretion
-
Wang, H.; Maeschler, P.; Antinozzi, P. A.; Hagenfldt, K. A.; Wollheim, C. B. Hepatocyte nuclear factor 4 alpha regulates the expression of pancreatic beta-cell genes implicated in glucose metabolism and nutrient-induced insulin secretion. J. Biol. Chem. 2000, 275, 35953-35959.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35953-35959
-
-
Wang, H.1
Maeschler, P.2
Antinozzi, P.A.3
Hagenfldt, K.A.4
Wollheim, C.B.5
-
29
-
-
0035406121
-
Hepatocyte nuclear factor-4 alpha involved in type 1 maturityonset diabetes of the young is a novel target of AMP-activated protein kinase
-
Leclerc, I.; Lenzner, C.; Gourdon, L.; Vaulont, S.; Kahn, A.; Viollet, B. Hepatocyte nuclear factor-4 alpha involved in type 1 maturityonset diabetes of the young is a novel target of AMP-activated protein kinase. Diabetes 2001, 50, 1515-1521.
-
(2001)
Diabetes
, vol.50
, pp. 1515-1521
-
-
Leclerc, I.1
Lenzner, C.2
Gourdon, L.3
Vaulont, S.4
Kahn, A.5
Viollet, B.6
-
30
-
-
0035807902
-
A transcription factor regulatory circuit in differentiated pancreatic cells
-
BoJ, S. F.; Parrrizas, M.; Maestro, M. A.; Ferrer, J. A transcription factor regulatory circuit in differentiated pancreatic cells. Proc. Nat. Acad. Sci. U.S.A. 2001, 98, 14481-14486.
-
(2001)
Proc. Nat. Acad. Sci. U.S.A.
, vol.98
, pp. 14481-14486
-
-
Boj, S.F.1
Parrrizas, M.2
Maestro, M.A.3
Ferrer, J.4
-
31
-
-
33748949690
-
Differential expression of HNF4 Spha isoforms in liver stem cells and hepatocytes
-
Li, K.; Zhang, H.; Wang, Y.; Wang, Y.; Feng, M. Differential expression of HNF4 Spha isoforms in liver stem cells and hepatocytes. T. Cell Blochem. 2006, 99, 558-564.
-
(2006)
T. Cell Blochem.
, vol.99
, pp. 558-564
-
-
Li, K.1
Zhang, H.2
Wang, Y.3
Wang, Y.4
Feng, M.5
-
32
-
-
0038757830
-
Hepatocyte nuclear factor 4 alpha controls the development of a hepatic epithelium and liver morphogenesis
-
Parvlz, F.; Matullo, C.; Garrison, W. D.; SavatskI, L.; Adamson, J. W.; Ning, G.; Kaestner, K. H.; Rossi, J. M.; Zaret, K. S.; Dune, S. A. Hepatocyte nuclear factor 4 alpha controls the development of a hepatic epithelium and liver morphogenesis. Nat Genet. 2003, 34, 292-296.
-
(2003)
Nat Genet.
, vol.34
, pp. 292-296
-
-
Parvlz, F.1
Matullo, C.2
Garrison, W.D.3
Savatski, L.4
Adamson, J.W.5
Ning, G.6
Kaestner, K.H.7
Rossi, J.M.8
Zaret, K.S.9
Dune, S.A.10
-
33
-
-
34548321724
-
Activation of bile acid biosynthesis by the p38 mitogen-activated protein kinase (MAPK): Hepatocyte nuclear factor-4apha phosphorylation by the p38 MAPK is required for cholesterol 7apha-hydroxylase expression
-
Xu, Z.; Tavares-Sanchez, O. L.; Li, Q.; Fernando, J.; Rodriguez, C. M.; Sfuder, E. J.; Pandak, W. M.; Hylemon, P. B.; Gil, G. Activation of bile acid biosynthesis by the p38 mitogen-activated protein kinase (MAPK): hepatocyte nuclear factor-4apha phosphorylation by the p38 MAPK is required for cholesterol 7apha-hydroxylase expression. J. Biol. Chem. 2007, 284, 24607-24614.
-
(2007)
J. Biol. Chem.
, vol.284
, pp. 24607-24614
-
-
Xu, Z.1
Tavares-Sanchez, O.L.2
Li, Q.3
Fernando, J.4
Rodriguez, C.M.5
Sfuder, E.J.6
Pandak, W.M.7
Hylemon, P.B.8
Gil, G.9
-
34
-
-
21444439970
-
Phosphorylation of c-Fos by members of the p38 MAPK family. Role in the AP-1 response to UV light
-
Tanos, T.; Marinissen, M. J.; Leskow, F. C.; Hochbaum, D.; Marfinetto, H.; Gutkind, J. S.; Coso, O. A. Phosphorylation of c-Fos by members of the p38 MAPK family. Role in the AP-1 response to UV light. J. Biol. Chem. 2005, 280, 18842-18852.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18842-18852
-
-
Tanos, T.1
Marinissen, M.J.2
Leskow, F.C.3
Hochbaum, D.4
Marfinetto, H.5
Gutkind, J.S.6
Coso, O.A.7
-
35
-
-
34247606483
-
Rewired ERK-JNK signSing pathways in melanoma
-
Lopez-Bergami, P.; Huang, C.; Goydos, J. S.; Yip, D.; Bar-Eli, M.; Herlyn, M.; Smalley, K. S.; Mahale, A.; Eroshkin, A.; Aaronson, S.; Ronai, Z. Rewired ERK-JNK signSing pathways in melanoma. Cancer Cell 2007, 11, 447-460.
-
(2007)
Cancer Cell
, vol.11
, pp. 447-460
-
-
Lopez-Bergami, P.1
Huang, C.2
Goydos, J.S.3
Yip, D.4
Bar-Eli, M.5
Herlyn, M.6
Smalley, K.S.7
Mahale, A.8
Eroshkin, A.9
Aaronson, S.10
Ronai, Z.11
-
36
-
-
24744441472
-
Developments changes of the expression of the genes regulated by retinoie acid in the small intestine of rats
-
Ogura, Y.; Suruga, K.; Takase, S.; Goda, T. Developments changes of the expression of the genes regulated by retinoie acid in the small intestine of rats. Life Sci. 2005, 77, 2804-2813.
-
(2005)
Life Sci.
, vol.77
, pp. 2804-2813
-
-
Ogura, Y.1
Suruga, K.2
Takase, S.3
Goda, T.4
-
37
-
-
68349131724
-
Role of peroxisome proliferator-activated receptor-alpha in fasting-mediated oxidative stress
-
Abdelmegeed, M. A.; Moon, K. H.; Hardwick, J. P.; Gonzalez, F. J.; Song, B. J. Role of peroxisome proliferator-activated receptor-alpha in fasting-mediated oxidative stress. Free Radical Biol. Med. 2009, 47, 767-778.
-
(2009)
Free Radical Biol. Med.
, vol.47
, pp. 767-778
-
-
Abdelmegeed, M.A.1
Moon, K.H.2
Hardwick, J.P.3
Gonzalez, F.J.4
Song, B.J.5
-
38
-
-
77949791216
-
The ubiquitln-proteasome system and its role in inflammatory and autoimmune diseases
-
Wang, J.; Maldonado, M. A. The ubiquitln-proteasome system and its role in inflammatory and autoimmune diseases. Cell Moll. Immunol. 2006, 4, 55-61.
-
(2006)
Cell Moll. Immunol.
, vol.4
, pp. 55-61
-
-
Wang, J.1
Maldonado, M.A.2
-
39
-
-
3242890973
-
Immunologic aspects of protein degradation by the ubiquitln-proteasome system
-
Reinstein, E. Immunologic aspects of protein degradation by the ubiquitln-proteasome system, Isr. Med. Assoc. J. 2004, 6, 420-424.
-
(2004)
Isr. Med. Assoc. J.
, vol.6
, pp. 420-424
-
-
Reinstein, E.1
-
40
-
-
0033033183
-
The proteasome
-
Bochtler, M.; Ditzel, L.; Groll, M.; Hartmann, C.; Huber, R. The proteasome. Annu. Rev. Bionhys. Biomol. Struct. 1999, 28, 295-317.
-
(1999)
Annu. Rev. Bionhys. Biomol. Struct.
, vol.28
, pp. 295-317
-
-
Bochtler, M.1
Ditzel, L.2
Groll, M.3
Hartmann, C.4
Huber, R.5
-
41
-
-
0035884036
-
Association of c-myc overexpression and hyperproliferation with arsenife-induced malignant transformation
-
Chen, H.; Liu, J.; Zhao, C. Q.; Diwan, B. A; Merrick, B. A.; Waalkes, M. P. Association of c-myc overexpression and hyperproliferation with arsenife-induced malignant transformation. Toxicol. Appl. Pharmacol. 2001, 175, 260-268.
-
(2001)
Toxicol. Appl. Pharmacol.
, vol.175
, pp. 260-268
-
-
Chen, H.1
Liu, J.2
Zhao, C.Q.3
Diwan, B.A.4
Merrick, B.A.5
Waalkes, M.P.6
-
42
-
-
1642430733
-
Myc pathways provoking cell suicide and cancer
-
Nilsson, J.A.; Cleveland, J. L. Myc pathways provoking cell suicide and cancer. Oncogene 2003, 22, 9007-9021.
-
(2003)
Oncogene
, vol.22
, pp. 9007-9021
-
-
Nilsson, J.A.1
Cleveland, J.L.2
-
43
-
-
0036781812
-
C-MYC: More than Just a matter of life and death
-
Pelengaris, S.; Khan, M.; Evan, G. c-MYC: more than Just a matter of life and death. Nat. Rev. Cancer 2002, 2, 764-776.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 764-776
-
-
Pelengaris, S.1
Khan, M.2
Evan, G.3
-
44
-
-
1642385412
-
Inflammation and Cancer II. Role of chronic inflammation and cytokine gene polymorphisms in the pathogenesis of gastrointestinal malignancy
-
Macarthur, M.; Georgina, L.; Hold, G. L.; El-Omar, E. M. Inflammation and Cancer II. Role of chronic inflammation and cytokine gene polymorphisms in the pathogenesis of gastrointestinal malignancy. Am. J. Physiol.: Gastrointest. Liver Physiol. 2004, 286, G515-G520.
-
(2004)
Am. J. Physiol.: Gastrointest. Liver Physiol.
, vol.286
-
-
Macarthur, M.1
Georgina, L.2
Hold, G.L.3
El-Omar, E.M.4
-
45
-
-
33751173224
-
Alteration of intracellular GSH levels and its role in microcystln-LR-induced DNA damage in human hepatoma HepG2 cells
-
Zegura, B.; Lah, T. T.; Fillpic, M. Alteration of intracellular GSH levels and its role in microcystln-LR-induced DNA damage in human hepatoma HepG2 cells. Mutat. Res. 2006, 611, 25-33.
-
(2006)
Mutat. Res.
, vol.611
, pp. 25-33
-
-
Zegura, B.1
Lah, T.T.2
Fillpic, M.3
-
46
-
-
66149103602
-
Exogenous thioredoxin prevents ethanol-induced oxidative damage and apoptosis in mouse liver
-
Cohen, J. I.; Roychowdhury, S.; DiBello, P. M.; Jacobsen, D. W.; Nagy, L. E. Exogenous thioredoxin prevents ethanol-induced oxidative damage and apoptosis in mouse liver. Hepatology 2009, 49, 1709-1717.
-
(2009)
Hepatology
, vol.49
, pp. 1709-1717
-
-
Cohen, J.I.1
Roychowdhury, S.2
Dibello, P.M.3
Jacobsen, D.W.4
Nagy, L.E.5
-
47
-
-
0036268269
-
The association between neuronal nitric oxide synthase and neuronal sensitivity in the brain after brain injury
-
Liu, P. K.; Robertson, C. S.; Valadka, A. The association between neuronal nitric oxide synthase and neuronal sensitivity in the brain after brain injury. Ann. N.Y. Acad. Sci. 2002, 962, 226-241.
-
(2002)
Ann. N.Y. Acad. Sci.
, vol.962
, pp. 226-241
-
-
Liu, P.K.1
Robertson, C.S.2
Valadka, A.3
-
48
-
-
67649370750
-
Oxidative stress contributes to silica nanoparticle-induced cytotoxicity in human embryonic kidney cells
-
Wang, F.; Gao, F.; Lan, M.; Yuan, H.; Huang, Y.; Liu, J. Oxidative stress contributes to silica nanoparticle-induced cytotoxicity in human embryonic kidney cells. Toxicol, in Vitro 2009, 23, 808815.
-
(2009)
Toxicol, in Vitro
, vol.23
, pp. 808815
-
-
Wang, F.1
Gao, F.2
Lan, M.3
Yuan, H.4
Huang, Y.5
Liu, J.6
-
49
-
-
67651158824
-
Role of oxidative stress in Scoholinduced liver injury
-
Cederbaum, A. I.; Lu, Y.; Wu, D. Role of oxidative stress in Scoholinduced liver injury. Arch. Toxicol. 2009, 83, 519-548.
-
(2009)
Arch. Toxicol.
, vol.83
, pp. 519-548
-
-
Cederbaum, A.I.1
Lu, Y.2
Wu, D.3
-
50
-
-
0029200072
-
Oxidant-sensitive and phosphorylation -dependent activation of NFkappa B and AI-1 in endothelial cells
-
Barchowsky, A.; Munro, S. R.; Morana, S. J.; Vincenti, M. P.; Treadwell, M. Oxidant-sensitive and phosphorylation -dependent activation of NFkappa B and AI-1 in endothelial cells. Am. J. Physiol. 1995, 269, 829-836.
-
(1995)
Am. J. Physiol.
, vol.269
, pp. 829-836
-
-
Barchowsky, A.1
Munro, S.R.2
Morana, S.J.3
Vincenti, M.P.4
Treadwell, M.5
-
51
-
-
0036783335
-
Pharmacogenomics, regulation and signaling pathways of phase 1 and II drug metabolizing enzymes
-
Rushmore, T. H.; Kong, A. N. Pharmacogenomics, regulation and signaling pathways of phase 1 and II drug metabolizing enzymes. Curr. Drug. Metab. 2002, 3, 481-490.
-
(2002)
Curr. Drug. Metab.
, vol.3
, pp. 481-490
-
-
Rushmore, T.H.1
Kong, A.N.2
-
52
-
-
51349166119
-
Cadmium activates the mitogenactivated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibiton of protein phosphatases 2A and 5
-
Chen, L.; Liu, L.; Huang, S. Cadmium activates the mitogenactivated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibiton of protein phosphatases 2A and 5. Free Radical Biol. Med. 2008, 45, 1035-1044.
-
(2008)
Free Radical Biol. Med.
, vol.45
, pp. 1035-1044
-
-
Chen, L.1
Liu, L.2
Huang, S.3
-
53
-
-
46849091975
-
Nat Med. TRPM2-mediated Ca2 + influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
-
Yamamoto, S.; Shlmizu, S.; Kiyonaka, S.; Takahashi, N.; Wajima, T.; Hara, Y.; Negoro, T.; Hiroi, T.; Kiuchi, Y.; Okada, T.; Kaneko, S.; Lange, I.; Fleig, A.; Penner, R.; Nishi, M.; Takeshima, H.; Mori, Y. Nat Med. TRPM2-mediated Ca2 + influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. Nat. Med. 2008, 14, 738-747.
-
(2008)
Nat. Med.
, vol.14
, pp. 738-747
-
-
Yamamoto, S.1
Shlmizu, S.2
Kiyonaka, S.3
Takahashi, N.4
Wajima, T.5
Hara, Y.6
Negoro, T.7
Hiroi, T.8
Kiuchi, Y.9
Okada, T.10
Kaneko, S.11
Lange, I.12
Fleig, A.13
Penner, R.14
Nishi, M.15
Takeshima, H.16
Mori, Y.17
-
54
-
-
0034678013
-
Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis
-
Yeldandi, A. V.; Rao, M. S.; Reddy, J. K. Hydrogen peroxide generation in peroxisome proliferator-induced oncogenesis. Mutat. Res. 2000, 448, 159-177.
-
(2000)
Mutat. Res.
, vol.448
, pp. 159-177
-
-
Yeldandi, A.V.1
Rao, M.S.2
Reddy, J.K.3
-
55
-
-
56649105360
-
Induction of hepatic glutathione s-transferases in male mice by prototypes of various classes of microsomal enzyme inducers
-
Knight, T. R.; Supratim Choudhuri, S.; Klaassen, C. D. Induction of Hepatic Glutathione S-Transferases in Male Mice by Prototypes of Various Classes of Microsomal Enzyme Inducers. Toxicol. Sci. 2008, 106, 329-338.
-
(2008)
Toxicol. Sci.
, vol.106
, pp. 329-338
-
-
Knight, T.R.1
Supratim Choudhuri, S.2
Klaassen, C.D.3
-
56
-
-
12844268268
-
Glutathione transferases
-
Hayes, H. D.; Flanagan, J. U.; Jowsey, I. R. Glutathione transferases. Annu. Rev. Pharmacol. Toxicol. 2005, 45, 51-88.
-
(2005)
Annu. Rev. Pharmacol. Toxicol.
, vol.45
, pp. 51-88
-
-
Hayes, H.D.1
Flanagan, J.U.2
Jowsey, I.R.3
-
57
-
-
30144439026
-
Nomenclature for mammalian soluble glutathione trasnferases
-
Mannervik, B.; Board, P. G.; Hayes, J. D.; Listowski, I.; Pearson, W. R. Nomenclature for mammalian soluble glutathione trasnferases. Methods Enzvmol. 2005, 401, 1-8.
-
(2005)
Methods Enzvmol.
, vol.401
, pp. 1-8
-
-
Mannervik, B.1
Board, P.G.2
Hayes, J.D.3
Listowski, I.4
Pearson, W.R.5
-
58
-
-
2442666471
-
Tissue-specific expression and subcellular distribution of murine glutathione S-transferase class kappa
-
Thomson, R. E.; Bigley, A. L.; Foster, J. R.; Jowsey, I. R.; Elcombe, C. R.; Orton, T. C.; Hayes, J. D. Tissue-specific expression and subcellular distribution of murine glutathione S-transferase class kappa. J. Histochem. Cytochem. 2009, 52, 653-662.
-
(2009)
J. Histochem. Cytochem.
, vol.52
, pp. 653-662
-
-
Thomson, R.E.1
Bigley, A.L.2
Foster, J.R.3
Jowsey, I.R.4
Elcombe, C.R.5
Orton, T.C.6
Hayes, J.D.7
-
59
-
-
33847711191
-
The use of histological defined specific biomarkers in drug development with special reference to the glutathione s-transferases
-
Shaw, M. The use of histological defined specific biomarkers in drug development with special reference to the glutathione s-transferases. Cancer Biomarkers 2005, 1, 69-74.
-
(2005)
Cancer Biomarkers
, vol.1
, pp. 69-74
-
-
Shaw, M.1
-
60
-
-
0025291893
-
Glutathione S-Transferases in relation to their role in the biotransformation of xenobiotics
-
Vos, R. M.; Bladeren, P. J. Glutathione S-Transferases in relation to their role in the biotransformation of xenobiotics. Chem.-Biol. Interact. 1990, 75, 241-265.
-
(1990)
Chem.-Biol. Interact.
, vol.75
, pp. 241-265
-
-
Vos, R.M.1
Bladeren, P.J.2
-
61
-
-
24044443913
-
Comparative study on glutathione transferases on rat brain and testis under the stress of phenobarbital and beta-methylcholanthrene
-
Thyagaraju, K.; Hemavathi, B.; Vasundhara, K.; Rao, A. D.; Devi, K. N. Comparative study on glutathione transferases on rat brain and testis under the stress of phenobarbital and beta-methylcholanthrene. T. Zheitan Univ., Sci. B 2005, 6, 759-769.
-
(2005)
T. Zheitan Univ., Sci. B
, vol.6
, pp. 759-769
-
-
Thyagaraju, K.1
Hemavathi, B.2
Vasundhara, K.3
Rao, A.D.4
Devi, K.N.5
|