Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrP res level disparity

Molecular Neurodegeneration

Volumn 7, Issue 1, 2012, Pages

  Lewis, Victoria ^a   Haigh, Cathryn L ^a   Masters, Colin L ^a   Hill, Andrew F ^a,b   Lawson, Victoria A ^a   Collins, Steven J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Fractionation; Prion disease; Prion infectivity; Prion protein; Protease resistance; Subcellular localisation

Indexed keywords

LIPID; MITOCHONDRIAL PROTEIN; PRION PROTEIN; PROTEINASE K;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CELL FRACTIONATION; ENDOPLASMIC RETICULUM; LIPID RAFT; MITOCHONDRION; MOUSE; NONHUMAN; PRION; PROTEIN CONTENT; PROTEIN LOCALIZATION; ULTRASOUND; VIRUS INFECTIVITY; VIRUS STRAIN; VIRUS TRANSMISSION; ANIMAL; BIOASSAY; CELL CULTURE; CHEMISTRY; DISEASE TRANSMISSION; METABOLISM; PRION DISEASE; PROTEIN CONFORMATION; PROTEIN FOLDING; RABBIT;

ANIMALS; BIOLOGICAL ASSAY; CELLS, CULTURED; ENDOPEPTIDASE K; MICE; PRION DISEASES; PROTEIN CONFORMATION; PROTEIN FOLDING; PRPC PROTEINS; RABBITS; SUBCELLULAR FRACTIONS;

EID: 84860113881     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/1750-1326-7-18     Document Type: Article

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