Extended period of asymptomatic prion disease after low dose inoculation: Assessment of detection methods and implications for infection control

Neurobiology of Disease

Volumn 20, Issue 2, 2005, Pages 336-346

  Collins, Steven J ^a,b   Lewis, Victoria ^a,b   Brazier, Marcus W ^a,b   Hill, Andrew F ^a,b   Lawson, Victoria A ^a,b   Klug, Genevieve M ^a,b   Masters, Colin L ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

Author keywords

Asymptomatic infection; Creutzfeldt Jakob disease; Detection methods; Preclinical infection; Prions; Subclinical infection; Transmissible spongiform encephalopathy

Indexed keywords

ISOPROTEIN; PHOSPHOTUNGSTIC ACID; PRION PROTEIN; PROTEINASE;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BOVINE SPONGIFORM ENCEPHALOPATHY; BRAIN HOMOGENATE; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; DIAGNOSTIC ACCURACY; DISEASE COURSE; DISEASE TRANSMISSION; EXPERIMENTAL INFECTION; FEMALE; HISTOPATHOLOGY; IMMUNOBLOTTING; INCUBATION TIME; INFECTION CONTROL; MEDICAL ASSESSMENT; MOUSE; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN VARIANT; TISSUE SECTION; TITRIMETRY; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL ASSAY; BLOTTING, WESTERN; BRAIN; DISEASE MODELS, ANIMAL; FEMALE; MALE; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; PATHOLOGY; PRION DISEASES; PRPC PROTEINS; PRPSC PROTEINS; TIME FACTORS;

EID: 26944435531     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.03.014     Document Type: Article

References (36)

1. E.A. Asante, J.M. Linehan, M. Desbruslais, S. Joiner, I. Gowland, A.L. Wood, J. Welch, A.F. Hill, S.E. Lloyd, J.D. Wadsworth, and J. Collinge BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein EMBO J. 21 2002 6358 6366
2. P.J. Bosque, C. Ryou, G. Telling, D. Peretz, G. Legname, S.J. DeArmond, and S.B. Prusiner Prions in skeletal muscle Proc. Natl. Acad. Sci. U. S. A. 99 2002 3812 3817
3. H. Büeler, A. Aguzzi, A. Sailer, R.A. Greiner, P. Autenreid, M. Aguet, and C. Weissmann Mice devoid of PrP are resistant to scrapie Cell 73 1993 1339 1347
4. H. Büeler, A. Raeber, A. Sailer, M. Fischer, A. Aguzzi, and C. Weissmann High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene Mol. Med. 1 1994 19 30
5. J. Collinge Variant Creutzfeldt-Jakob disease Lancet 354 1999 317 323
6. S.C. Collis, and R.H. Kimberlin Long-term persistence of scrapie infection in mouse spleens in the absence of clinical disease FEMS Microbiol. Lett. 29 1985 111 114
7. S. Collins, M.G. Law, A. Fletcher, A. Boyd, J. Kaldor, and C.L. Masters Surgical treatment and risk of sporadic Creutzfeldt-Jakob disease: a case-control study Lancet 353 1999 693 697
8. S. Collins, A. Boyd, A. Fletcher, J. Kaldor, A. Hill, S. Farish, C. McLean, Z. Ansari, M. Smith, and C.L. Masters Creutzfeldt-Jakob disease cluster in an Australian rural city Ann. Neurol. 52 2002 115 118
9. S. Collins, A. Boyd, J.S. Lee, V. Lewis, A. Fletcher, C.A. McLean, M. Law, J. Kaldor, M.J. Smith, and C.L. Masters Creutzfeldt-Jakob disease in Australia 1970-1999 Neurology 59 2002 1365 1371
10. A.G. Dickinson, H. Fraser, and G.W. Outram Scrapie incubation time can exceed natural lifespan Nature 256 1975 732 733
11. M. Fischer, T. Rulicke, A. Raeber, A. Sailer, M. Moser, B. Oesch, S. Brandner, A. Aguzzi, and C. Weissmann Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie EMBO J. 15 1996 1255 1264
12. R. Frigg, M.A. Klein, I. Hegyi, R.M. Zinkernagel, and A. Aguzzi Scrapie pathogenesis in subclinically infected B-cell-deficient mice J. Virol. 73 1999 9584 9588
13. M. Glatzel, E. Abela, M. Maissen, and A. Aguzzi Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease N. Engl. J. Med. 349 2003 1812 1820
14. A.F. Hill, R.J. Butterworth, S. Joiner, G. Jackson, M.N. Rossor, D.J. Thomas, A. Frosh, N. Tolley, J.E. Bell, M. Spencer, A. King, S. Al-Sarrag, J.W. Ironside, P.L. Lantos, and J. Collinge Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples Lancet 353 1999 183 189
15. A.F. Hill, S. Joiner, J. Linehan, M. Desbruslais, P.L. Lantos, and J. Collinge Species-barrier-independent prion replication in apparently resistant species Proc. Natl. Acad. Sci. U. S. A. 97 2000 10248 10253
16. D.A. Hilton, E. Fathers, P. Edwards, J.W. Ironside, and J. Zajicek Prion immunoreactivity in appendix before clinical onset of variant Creutzfeldt-Jakob disease Lancet 352 1998 703 704
17. D.A. Hilton, A.C. Ghani, L. Conyers, P. Edwards, L. McCardle, M. Penney, D. Ritchie, and J.W. Ironside Accumulation of prion protein in tonsil and appendix: review of tissue samples BMJ 325 2002 633 634
18. D.A. Hilton, A.C. Ghani, L. Conyers, P. Edwards, L. McCardle, D. Ritchie, M. Penney, D. Hegazy, and J.W. Ironside Prevalence of lymphoreticular prion protein accumulation in UK tissue samples J. Pathol. 203 2004 733 739
19. D.C. Lee, C.J. Stenland, R.C. Hartwell, E.K. Ford, K. Cai, J.L. Miller, K.J. Gilligan, R. Rubenstein, M. Fournel, and S.R. Petteway Jr. Monitoring plasma processing steps with a sensitive Western blot assay for the detection of the prion protein J. Virol. Methods 84 2000 77 89
20. V. Lewis, S. Collins, A.F. Hill, A. Boyd, C.A. McLean, M. Smith, and C.L. Masters Novel prion protein insert mutation associated with prolonged neurodegenerative illness Neurology 60 2003 1620 1624
21. C.A. Llewelyn, P.E. Hewitt, R.S. Knight, K. Amar, S. Cousens, J. Mackenzie, and R.G. Will Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion Lancet 363 2004 417 421
22. C.L. Masters, B.A. Kakulas, M.P. Alpers, D.C. Gajdusek, and C.J. Gibbs Jr. Preclinical lesions and their progression in the experimental spongiform encephalopathies (kuru and Creutzfeldt-Jakob disease in primates) J. Neuropathol. Exp. Neurol. 35 1976 593 605
23. S.B. Prusiner Prion diseases and the BSE crisis (review) Science 278 1997 245 251
24. R. Race, and B. Chesebro Scrapie infectivity found in resistant species Nature 392 1998 770
25. R. Race, A. Raines, G.J. Raymond, B. Caughey, and B. Chesebro Long-term subclinical carrier state precedes scrapie replication and adaptation in a resistant species: analogies to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease in humans J. Virol. 75 2001 10106 10112
26. R. Race, K. Meade-White, A. Raines, G.J. Raymond, B. Caughey, and B. Chesebro Subclinical scrapie infection in a resistant species: persistence, replication, and adaptation of infectivity during four passages J. Infect. Dis. 186 Suppl. 2 2002 S166 S170
27. L.J. Reed, and H. Muench A simple method of estimating fifty per cent endpoints Am. J. Hygiene 27 1938 493 497
28. J.G. Safar, M. Scott, J. Monaghan, C. Deering, S. Didorenko, J. Vergara, H. Ball, G. Legname, E. Leclerc, L. Solforosi, H. Serban, D. Groth, D.R. Burton, S.B. Prusiner, and R.A. Williamson Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice Nat. Biotechnol. 20 2002 1147 1150
29. J. Tateishi, M. Ohta, M. Koga, Y. Sato, and Y. Kuroiwa Transmission of chronic spongiform encephalopathy with kuru plaques from humans to small rodents Ann. Neurol. 5 1979 581 584
30. D.M. Taylor, I. McConnell, and C.E. Ferguson Closely similar values obtained when the ME7 strain of scrapie agent was titrated in parallel by two individuals in separate laboratories using two sublines of C57BL mice J. Virol. Methods 86 2000 35 40
31. G.C. Telling, T. Haga, M. Torchia, P. Tremblay, S.J. DeArmond, and S.B. Prusiner Interactions between wild-type and mutant prion proteins modulate neurodegeneration transgenic mice Genes Dev. 10 1996 1736 1750
32. A.M. Thackray, M.A. Klein, A. Aguzzi, and R. Bujdoso Chronic subclinical prion disease induced by low-dose inoculum J. Virol. 76 2002 2510 2517
33. J.D. Wadsworth, S. Joiner, A.F. Hill, T.A. Campbell, M. Desbruslais, P.J. Luthert, and J. Collinge Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay Lancet 358 2001 171 180
34. H.J. Ward, D. Everington, E.A. Croes, A. Alperovitch, N. Delasnerie-Lauprêtre, I. Zerr, S. Poser, and C.M. van Duijn Sporadic Creutzfeldt-Jakob disease and surgery: a case-control study using community controls Neurology 59 2002 543 548
35. A.R. White, P. Enever, M. Tayebi, R. Mushens, J. Linehan, S. Brandner, D. Anstee, J. Collinge, and S. Hawke Monoclonal antibodies inhibit prion replication and delay the development of prion disease Nature 422 2003 80 83
36. I. Zlotnik Observations on the experimental transmission of scrapie of various origins to laboratory animals D.C. Gajdusek C.J. Gibbs M.P. Alpers Slow, Latent, and Temperate Virus Infections: National Institute of Neurological Diseases and Blindness, Monograph 2. Proceedings of the Workshop and Symposium on Slow, Latent, and Temperate Virus Infections, National Institute of Health, 1964 Dec 7-9, Bethesda 1965 U.S. Government Printing Office Washington, DC 237 248