Differential effects of prion particle size on infectivity in vivo and in vitro

Biochemical and Biophysical Research Communications

Volumn 369, Issue 3, 2008, Pages 924-928

  Weber, Petra ^a   Reznicek, Lukas ^a   Mitteregger, Gerda ^a   Kretzschmar, Hans ^a   Giese, Armin ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Aggregation; Clearance; Fragmentation; Infectivity; N2a; Prion; Size distribution; Sonication

Indexed keywords

ISOPROTEIN; PRION PROTEIN; PYROXYLIN;

ADSORPTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INFECTION; CLEARANCE; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN AGGREGATION;

ANIMALS; BIOLOGICAL ASSAY; BRAIN CHEMISTRY; MICE; MICE, INBRED C57BL; PARTICLE SIZE; PRION DISEASES; PROTEIN FOLDING; PRPSC PROTEINS; SONICATION;

EID: 41149127608     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.02.115     Document Type: Article

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