Febrile range temperature represses TNF-α gene expression in LPS-stimulated macrophages by selectively blocking recruitment of Sp1 to the TNF-α promoter

Cell Stress and Chaperones

Volumn 15, Issue 5, 2010, Pages 665-673

  Cooper, Zachary A ^a   Singh, Ishwar S ^a,b   Hasday, Jeffrey D ^a,b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b BALTIMORE VA MEDICAL CENTER   (United States)

Author keywords

Fever; Hyperthermia; Repression; Sp1; TNF

Indexed keywords

HEAT SHOCK TRANSCRIPTION FACTOR 1; HISTONE H3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

5' UNTRANSLATED REGION; ACETYLATION; ANIMAL CELL; ARTICLE; BODY TEMPERATURE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA BINDING; FEVER; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE SEQUENCE; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION;

5' UNTRANSLATED REGIONS; ANIMALS; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; PROMOTER REGIONS, GENETIC; SP1 TRANSCRIPTION FACTOR; TEMPERATURE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77955717716     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1007/s12192-010-0179-9     Document Type: Article

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