A conserved TGFβ1/HuR feedback circuit regulates the fibrogenic response in fibroblasts

Cellular Signalling

Volumn 24, Issue 7, 2012, Pages 1426-1432

  Bai, Danna ^a,b   Gao, Qun ^a,b   Li, Chengxiang ^a   Ge, Lan ^c   Gao, Yan ^b   Wang, Haichang ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b 323 Hospital of PLA   (China)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Fibroblast; HuR; MRNA stability; TGF 1

Indexed keywords

FIBRONECTIN; HUR PROTEIN; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; ENZYME REGULATION; FEEDBACK SYSTEM; FIBROBLAST; FIBROGENESIS; FIBROSIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REGULATORY MECHANISM; RNA STABILITY;

3' UNTRANSLATED REGIONS; ANIMALS; CELLS, CULTURED; EXTRACELLULAR MATRIX; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION; HSP27 HEAT-SHOCK PROTEINS; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; MALE; MOLECULAR TARGETED THERAPY; MYOCARDIUM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROMOTER REGIONS, GENETIC; RATS; RNA STABILITY; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84859986512     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2012.03.003     Document Type: Article

References (28)

1. Leask A. Circulation Research 2010, 106:1675-1680.
2. de Jong S., van Veen T.A., de Bakker J.M., Vos M.A., van Rijen H.V. Journal of Cardiovascular Pharmacology 2011, 57:522-535.
3. Gabbiani G. The Journal of Pathology 2003, 200:500-503.
4. Kane C.J., Hebda P.A., Mansbridge J.N., Hanawalt P.C. Journal of Cellular Physiology 1991, 148:157-173.
5. Leask A., Abraham D.J. The FASEB Journal 2004, 18:816-827.
6. Bujak M., Frangogiannis N.G. Cardiovascular Research 2007, 74:184-195.
7. Ong V.H., Carulli M.T., Xu S., Khan K., Lindahl G., Abraham D.J., Denton C.P. Experimental Cell Research 2009, 315:151-161.
8. Ihn H., Yamane K., Tamaki K. The Journal of Investigative Dermatology 2005, 125:247-255.
9. Ikeuchi M., Tsutsui H., Shiomi T., Matsusaka H., Matsushima S., Wen J., Kubota T., Takeshita A. Cardiovascular Research 2004, 64:526-535.
10. Bujak M., Ren G., Kweon H.J., Dobaczewski M., Reddy A., Taffet G., Wang X.F., Frangogiannis N.G. Circulation 2007, 116:2127-2138.
11. Okada H., Takemura G., Kosai K., Li Y., Takahashi T., Esaki M., Yuge K., Miyata S., Maruyama R., Mikami A., Minatoguchi S., Fujiwara T., Fujiwara H. Circulation 2005, 111:2430-2437.
12. Scheel C., Eaton E.N., Li S.H., Chaffer C.L., Reinhardt F., Kah K.J., Bell G., Guo W., Rubin J., Richardson A.L., Weinberg R.A. Cell 2011, 145:926-940.
13. Moore M.J. Science 2005, 309:1514-1518.
14. Chen C.Y., Gherzi R., Ong S.E., Chan E.L., Raijmakers R., Pruijn G.J., Stoecklin G., Moroni C., Mann M., Karin M. Cell 2001, 107:451-464.
15. Chen C.Y., Shyu A.B. Trends in Biochemical Sciences 1995, 20:465-470.
16. Cherry J., Karschner V., Jones H., Pekala P.H. In Vivo 2006, 20:17-23.
17. Gorospe M. Cell Cycle 2003, 2:412-414.
18. Nabors L.B., Gillespie G.Y., Harkins L., King P.H. Cancer Research 2001, 61:2154-2161.
19. Hao J., Wang B., Jones S.C., Jassal D.S., Dixon I.M. American Journal of Physiology - Heart and Circulatory Physiology 2000, 279:H3020-H3030.
20. Kawai T., Lal A., Yang X., Galban S., Mazan-Mamczarz K., Gorospe M. Molecular and Cellular Biology 2006, 26:3295-3307.
21. Yang G., Lu X., Wang L., Bian Y., Fu H., Wei M., Pu J., Jin L., Yao L., Lu Z. Cell Cycle 2011, 10:2703-2713.
22. Danilin S., Sourbier C., Thomas L., Lindner V., Rothhut S., Dormoy V., Helwig J.J., Jacqmin D., Lang H., Massfelder T. Carcinogenesis 2010, 31:1018-1026.
23. Farooq F., Balabanian S., Liu X., Holcik M., MacKenzie A. Human Molecular Genetics 2009, 18:4035-4045.
24. Bakin A.V., Rinehart C., Tomlinson A.K., Arteaga C.L. Journal of Cell Science 2002, 115:3193-3206.
25. Dobaczewski M., Bujak M., Li N., Gonzalez-Quesada C., Mendoza L.H., Wang X.F., Frangogiannis N.G. Circulation Research 2010, 107:418-428.
26. Wightman B., Ha I., Ruvkun G. Cell 1993, 75:855-862.
27. Krishnamurthy P., Lambers E., Verma S., Thorne T., Qin G., Losordo D.W., Kishore R. The FASEB Journal 2010, 24:2484-2494.
28. Krishnamurthy P., Rajasingh J., Lambers E., Qin G., Losordo D.W., Kishore R. Circulation Research 2009, 104:e9-e18.