메뉴 건너뛰기




Volumn 863, Issue , 2012, Pages 35-45

DNA methylation and histone modifications in breast cancer

Author keywords

Breast cancer; DNA promoter hypermethylation; Global hypomethylation; Histones acetylation; Histones deacetylases; Histones methylation

Indexed keywords

HISTONE;

EID: 84859971532     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-612-8_3     Document Type: Article
Times cited : (17)

References (70)
  • 1
    • 0003964361 scopus 로고    scopus 로고
    • American Cancer Society. Atlanta, Georgia, American Cancer Society
    • American Cancer Society. Cancer Facts and Figures 2010. (2010). Atlanta, Georgia, American Cancer Society.
    • (2010) Cancer Facts and Figures 2010
  • 2
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D. and Weinberg, R. A. (2000) The hallmarks of cancer. Cell 100, 57-70. (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 3
    • 36048947234 scopus 로고    scopus 로고
    • Breast cancer: Origins and evolution
    • DOI 10.1172/JCI33295
    • Polyak, K. (2007) Breast cancer: Origins and evolution. J. Clin. Invest 117, 3155-3163. (Pubitemid 350096968)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.11 , pp. 3155-3163
    • Polyak, K.1
  • 4
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • DOI 10.1038/nm1087
    • Vogelstein, B. and Kinzler, K. W. (2004) Cancer genes and the pathways they control. Nat Med 10, 789-799. (Pubitemid 39070849)
    • (2004) Nature Medicine , vol.10 , Issue.8 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 5
    • 0037068360 scopus 로고    scopus 로고
    • DNA methylation and breast carcinogenesis
    • DOI 10.1038/sj.onc.1205606
    • Widschwendter, M. and Jones, P. A. (2002) DNA methylation and breast carcinogenesis. Oncogene 21, 5462-5482. (Pubitemid 34983482)
    • (2002) Oncogene , vol.21 , pp. 5462-5482
    • Widschwendter, M.1    Jones, P.A.2
  • 6
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer - A mechanism for early oncogenic pathway addiction?
    • DOI 10.1038/nrc1799, PII N1799
    • Baylin, S. B. and Ohm, J. E. (2006) Epigenetic gene silencing in cancer-A mechanism for early oncogenic pathway addiction? Nat Rev Cancer 6, 107-116. (Pubitemid 43361543)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.2 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 7
    • 0242584454 scopus 로고    scopus 로고
    • Chromosomal instability and tumors promoted by DNA hypomethylation
    • DOI 10.1126/science.1083557
    • Eden, A., Gaudet, F., Waghmare, A., and Jaenisch, R. (2003) Chromosomal instability and tumors promoted by DNA hypomethylation. Science 300, 455. (Pubitemid 36444319)
    • (2003) Science , vol.300 , Issue.5618 , pp. 455
    • Eden, A.1    Gaudet, F.2    Waghmare, A.3    Jaenisch, R.4
  • 8
    • 1042278765 scopus 로고    scopus 로고
    • The history of cancer epigenetics
    • Feinberg, A. P. and Tycko, B. (2004) The history of cancer epigenetics. Nat Rev Cancer 4, 143-153. (Pubitemid 38198742)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.2 , pp. 143-153
    • Feinberg, A.P.1    Tycko, B.2
  • 9
    • 61549112191 scopus 로고    scopus 로고
    • Epigenomics and breast cancer
    • Lo, P. K. and Sukumar, S. (2008) Epigenomics and breast cancer. Pharmacogenomics 9, 1879-1902.
    • (2008) Pharmacogenomics , vol.9 , pp. 1879-1902
    • Lo, P.K.1    Sukumar, S.2
  • 11
    • 0035870248 scopus 로고    scopus 로고
    • A gene hypermethylation profile of human cancer
    • Esteller, M., Corn, P. G., Baylin, S. B., and Herman, J. G. (2001) A gene hypermethylation profile of human cancer. Cancer Res. 61, 3225-3229. (Pubitemid 32695003)
    • (2001) Cancer Research , vol.61 , Issue.8 , pp. 3225-3229
    • Esteller, M.1    Corn, P.G.2    Baylin, S.B.3    Herman, J.G.4
  • 12
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • DOI 10.1038/nrg2005, PII NRG2005
    • Esteller, M. (2007) Cancer epigenomics: DNA methylomes and histone-modifi cation maps. Nat. Rev. Genet. 8, 286-298. (Pubitemid 46439286)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.4 , pp. 286-298
    • Esteller, M.1
  • 13
    • 0024365892 scopus 로고
    • Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma
    • Greger, V., Passarge, E., Hopping, W., Messmer, E., and Horsthemke, B. (1989) Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum. Genet. 83, 155-158. (Pubitemid 19234564)
    • (1989) Human Genetics , vol.83 , Issue.2 , pp. 155-158
    • Greger, V.1    Passarge, E.2    Hopping, W.3    Messmer, E.4    Horsthemke, B.5
  • 15
    • 79953123510 scopus 로고    scopus 로고
    • Breast cancer methylomes establish an epigenomic foundation for metastasis
    • 75ra25
    • van Hoesel, A. Q., Van, d., V, Kuppen, P. J., Putter, H., de Kruijf, E. M., van Nes, J. G., Giuliano, A. E., and Hoon, D. S. (2011) Primary tumor classifi cation according to methylation pattern is prognostic in patients with early stage ER-negative breast cancer. Breast Cancer Res. Treat 16. Fang, F., Turcan, S., Rimner, A., Kaufman, A., Giri, D., Morris, L. G., Shen, R., Seshan, V., Mo, Q., et al. (2011) Breast cancer methylomes establish an epigenomic foundation for metastasis. Sci Transl Med 3, 75ra25.
    • (2011) Sci. Transl. Med. , vol.3
    • Fang, F.1    Turcan, S.2    Rimner, A.3    Kaufman, A.4    Giri, D.5    Morris, L.G.6    Shen, R.7    Seshan, V.8    Mo, Q.9
  • 16
    • 2642578598 scopus 로고    scopus 로고
    • Tumor-derived aberrant methylation in plasma of invasive ductal breast cancer patients: Clinical implications
    • Hu, X. C., Wong, I. H., and Chow, L. W. (2003) Tumor-derived aberrant methylation in plasma of invasive ductal breast cancer patients: Clinical implications. Oncol Rep 10, 1811-1815.
    • (2003) Oncol. Rep. , vol.10 , pp. 1811-1815
    • Hu, X.C.1    Wong, I.H.2    Chow, L.W.3
  • 17
    • 34447100205 scopus 로고    scopus 로고
    • Promoter hypermethylation of TMS1, BRCA1, ERα and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients
    • DOI 10.1016/j.lfs.2007.05.012, PII S0024320507003748
    • Mirza, S., Sharma, G., Prasad, C. P., Parshad, R., Srivastava, A., Gupta, S. D., and Ralhan, R. (2007) Promoter hypermethylation of TMS1, BRCA1, ERalpha and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients. Life Sci 81, 280-287. (Pubitemid 47030571)
    • (2007) Life Sciences , vol.81 , Issue.4 , pp. 280-287
    • Mirza, S.1    Sharma, G.2    Prasad, C.P.3    Parshad, R.4    Srivastava, A.5    Gupta, S.D.6    Ralhan, R.7
  • 18
    • 34147134560 scopus 로고    scopus 로고
    • ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients
    • DOI 10.1016/j.lfs.2007.02.026, PII S0024320507001828
    • Sharma, G., Mirza, S., Prasad, C. P., Srivastava, A., Gupta, S. D., and Ralhan, R. (2007) Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients. Life Sci 80, 1873-1881. (Pubitemid 46562520)
    • (2007) Life Sciences , vol.80 , Issue.20 , pp. 1873-1881
    • Sharma, G.1    Mirza, S.2    Prasad, C.P.3    Srivastava, A.4    Gupta, S.D.5    Ralhan, R.6
  • 19
    • 4644297522 scopus 로고    scopus 로고
    • Tumor suppressor gene promoter hypermethylation in serum of breast cancer patients
    • DOI 10.1158/1078-0432.CCR-04-0597
    • Dulaimi, E., Hillinck, J., Ibanez, d. C., I, Al-Saleem, T., and Cairns, P. (2004) Tumor suppressor gene promoter hypermethylation in serum of breast cancer patients. Clin. Cancer Res. 10, 6189-6193. (Pubitemid 39287525)
    • (2004) Clinical Cancer Research , vol.10 , Issue.18 , pp. 6189-6193
    • Dulaimi, E.1    Hillinck, J.2    De Caceres, I.I.3    Al-Saleem, T.4    Cairns, P.5
  • 20
    • 79551513940 scopus 로고    scopus 로고
    • Hypermethylation of tumor suppressor genes involved in critical regulatory pathways for developing a blood-based test in breast cancer
    • Radpour, R., Barekati, Z., Kohler, C., Lv, Q., Burki, N., Diesch, C., Bitzer, J., Zheng, H., Schmid, S., and Zhong, X. Y. (2011) Hypermethylation of tumor suppressor genes involved in critical regulatory pathways for developing a blood-based test in breast cancer. PLoS One 6, e16080.
    • (2011) Plos One , vol.6
    • Radpour, R.1    Barekati, Z.2    Kohler, C.3    Lv, Q.4    Burki, N.5    Diesch, C.6    Bitzer, J.7    Zheng, H.8    Schmid, S.9    Zhong, X.Y.10
  • 22
    • 77955591555 scopus 로고    scopus 로고
    • MicroRNAs and their target gene networks in breast cancer
    • O'Day, E. and Lal, A. (2010) MicroRNAs and their target gene networks in breast cancer. Breast Cancer Res. 12, 201.
    • (2010) Breast Cancer Res. , vol.12 , pp. 201
    • O'Day, E.1    Lal, A.2
  • 23
    • 77149135270 scopus 로고    scopus 로고
    • Breast cancer epigenetics: From DNA methylation to microRNAs
    • Veeck, J. and Esteller, M. (2010) Breast cancer epigenetics: From DNA methylation to microRNAs. J Mammary Gland Biol Neoplasia 15, 5-17.
    • (2010) J. Mammary Gland. Biol. Neoplasia , vol.15 , pp. 5-17
    • Veeck, J.1    Esteller, M.2
  • 27
    • 78549249846 scopus 로고    scopus 로고
    • Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells
    • de Souza Rocha, S. P., Breiling, A., Gupta, N., Malekpour, M., Youns, M., Omranipour, R., Malekpour, F., Volinia, S., Croce, C. M., et al. (2010) Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells. Cancer Res. 70, 9175-9184.
    • (2010) Cancer Res. , vol.70 , pp. 9175-9184
    • De Souza Rocha, S.P.1    Breiling, A.2    Gupta, N.3    Malekpour, M.4    Youns, M.5    Omranipour, R.6    Malekpour, F.7    Volinia, S.8    Croce, C.M.9
  • 28
    • 79551604098 scopus 로고    scopus 로고
    • MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer
    • Png, K. J., Yoshida, M., Zhang, X. H., Shu, W., Lee, H., Rimner, A., Chan, T. A., Comen, E., Andrade, V. P., et al. (2011) MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer. Genes. Dev. 25, 226-231.
    • (2011) Genes. Dev. , vol.25 , pp. 226-231
    • Png, K.J.1    Yoshida, M.2    Zhang, X.H.3    Shu, W.4    Lee, H.5    Rimner, A.6    Chan, T.A.7    Comen, E.8    Andrade, V.P.9
  • 29
    • 0036324032 scopus 로고    scopus 로고
    • DNA hypomethylation, cancer, the immunodeficiency, centromeric region instability, facial anomalies syndrome and chromosomal rearrangements
    • Ehrlich, M. (2002) DNA hypomethylation, cancer, the immunodefi ciency, centromeric region instability, facial anomalies syndrome and chromosomal rearrangements. J Nutr 132, 2424 S-2429 S. (Pubitemid 34848120)
    • (2002) Journal of Nutrition , vol.132 , Issue.SUPPL.
    • Ehrlich, M.1
  • 30
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones, P. A. and Baylin, S. B. (2002) The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3, 415-428. (Pubitemid 34587077)
    • (2002) Nature Reviews Genetics , vol.3 , Issue.6 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 31
    • 0032894211 scopus 로고    scopus 로고
    • Global DNA hypomethylation in breast carcinoma: Correlation with prognostic factors and tumor progression
    • DOI 10.1002/(SICI)1097-0142(19990101)85:1<112::AID-CNCR16>3.0.CO;2- T
    • Soares, J., Pinto, A. E., Cunha, C. V., Andre, S., Barao, I., Sousa, J. M., and Cravo, M. (1999) Global DNA hypomethylation in breast carcinoma: Correlation with prognostic factors and tumor progression. Cancer 85, 112-118. (Pubitemid 29031364)
    • (1999) Cancer , vol.85 , Issue.1 , pp. 112-118
    • Soares, J.1    Pinto, A.E.2    Cunha, C.V.3    Andre, S.4    Barao, I.5    Sousa, J.M.6    Cravo, M.7
  • 34
    • 77955787215 scopus 로고    scopus 로고
    • Aberrant promoter hypermethylation and genomic hypomethylation in tumor, adjacent normal tissues and blood from breast cancer patients
    • Cho, Y. H., Yazici, H., Wu, H. C., Terry, M. B., Gonzalez, K., Qu, M., Dalay, N., and Santella, R. M. (2010) Aberrant promoter hypermethylation and genomic hypomethylation in tumor, adjacent normal tissues and blood from breast cancer patients. Anticancer Res 30, 2489-2496.
    • (2010) Anticancer Res. , vol.30 , pp. 2489-2496
    • Cho, Y.H.1    Yazici, H.2    Wu, H.C.3    Terry, M.B.4    Gonzalez, K.5    Qu, M.6    Dalay, N.7    Santella, R.M.8
  • 35
    • 33845490045 scopus 로고    scopus 로고
    • Radiation-induced molecular changes in rat mammary tissue: Possible implications for radiation-induced carcinogenesis
    • DOI 10.1080/09553000600960027, PII L57642GR44338733
    • Loree, J., Koturbash, I., Kutanzi, K., Baker, M., Pogribny, I., and Kovalchuk, O. (2006) Radiation-induced molecular changes in rat mammary tissue: Possible implications for radiation-induced carcinogenesis. Int J Radiat Biol 82, 805-815. (Pubitemid 44915736)
    • (2006) International Journal of Radiation Biology , vol.82 , Issue.11 , pp. 805-815
    • Loree, J.1    Koturbash, I.2    Kutanzi, K.3    Baker, M.4    Pogribny, I.5    Kovalchuk, O.6
  • 39
    • 33746324216 scopus 로고    scopus 로고
    • Chromatin modifications by methylation and ubiquitination: Implications in the regulation of gene expression
    • DOI 10.1146/annurev.biochem.75.103004.142422
    • Shilatifard, A. (2006) Chromatin modifi cations by methylation and ubiquitination: Implications in the regulation of gene expression. Annu Rev Biochem 75, 243-269. (Pubitemid 44118033)
    • (2006) Annual Review of Biochemistry , vol.75 , pp. 243-269
    • Shilatifard, A.1
  • 40
    • 34249026300 scopus 로고    scopus 로고
    • High-resolution profiling of histone methylations in the human genome
    • DOI 10.1016/j.cell.2007.05.009, PII S0092867407006009
    • Barski, A., Cuddapah, S., Cui, K., Roh, T. Y., Schones, D. E., Wang, Z., Wei, G., Chepelev, I., and Zhao, K. (2007) High-resolution profi ling of histone methylations in the human genome. Cell 129, 823-837. (Pubitemid 46802390)
    • (2007) Cell , vol.129 , Issue.4 , pp. 823-837
    • Barski, A.1    Cuddapah, S.2    Cui, K.3    Roh, T.-Y.4    Schones, D.E.5    Wang, Z.6    Wei, G.7    Chepelev, I.8    Zhao, K.9
  • 44
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • DOI 10.1126/science.1063127
    • Jenuwein, T. and Allis, C. D. (2001) Translating the histone code. Science 293, 1074-1080. (Pubitemid 32758077)
    • (2001) Science , vol.293 , Issue.5532 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 45
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • DOI 10.1016/j.cell.2007.02.005, PII S0092867407001845
    • Kouzarides, T. (2007) Chromatin modifi cations and their function. Cell 128, 693-705. (Pubitemid 46273577)
    • (2007) Cell , vol.128 , Issue.4 , pp. 693-705
    • Kouzarides, T.1
  • 47
    • 65949086183 scopus 로고    scopus 로고
    • Global histone modifi cations in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome
    • Elsheikh, S. E., Green, A. R., Rakha, E. A., Powe, D. G., Ahmed, R. A., Collins, H. M., Soria, D., Garibaldi, J. M., Paish, C. E., et al. (2009) Global histone modifi cations in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome. Cancer Res. 69, 3802-3809.
    • (2009) Cancer Res. , vol.69 , pp. 3802-3809
    • Elsheikh, S.E.1    Green, A.R.2    Rakha, E.A.3    Powe, D.G.4    Ahmed, R.A.5    Collins, H.M.6    Soria, D.7    Garibaldi, J.M.8    Paish, C.E.9
  • 48
    • 69449102464 scopus 로고    scopus 로고
    • Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes
    • Wang, Z., Zang, C., Cui, K., Schones, D. E., Barski, A., Peng, W., and Zhao, K. (2009) Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes. Cell 138, 1019-1031.
    • (2009) Cell , vol.138 , pp. 1019-1031
    • Wang, Z.1    Zang, C.2    Cui, K.3    Schones, D.E.4    Barski, A.5    Peng, W.6    Zhao, K.7
  • 49
    • 77149156308 scopus 로고    scopus 로고
    • The role of histone modifi cations and variants in regulating gene expression in breast cancer
    • Dalvai, M. and Bystricky, K. (2010) The role of histone modifi cations and variants in regulating gene expression in breast cancer. J Mammary Gland Biol Neoplasia 15, 19-33.
    • (2010) J. Mammary Gland. Biol. Neoplasia , vol.15 , pp. 19-33
    • Dalvai, M.1    Bystricky, K.2
  • 50
    • 2942612219 scopus 로고    scopus 로고
    • P300/CBP and cancer
    • DOI 10.1038/sj.onc.1207118
    • Iyer, N. G., Ozdag, H., and Caldas, C. (2004) p300/CBP and cancer. Oncogene 23, 4225-4231. (Pubitemid 38758588)
    • (2004) Oncogene , vol.23 , Issue.24 , pp. 4225-4231
    • Iyer, N.G.1    Ozdag, H.2    Caldas, C.3
  • 51
    • 34547896549 scopus 로고    scopus 로고
    • The MYST family of histone acetyltransferases and their intimate links to cancer
    • DOI 10.1038/sj.onc.1210608, PII 1210608
    • Avvakumov, N. and Cote, J. (2007) The MYST family of histone acetyltransferases and their intimate links to cancer. Oncogene 26, 5395-5407. (Pubitemid 47255922)
    • (2007) Oncogene , vol.26 , Issue.37 , pp. 5395-5407
    • Avvakumov, N.1    Cote, J.2
  • 54
    • 39649119288 scopus 로고    scopus 로고
    • The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma
    • DOI 10.1002/ijc.23283
    • Pfi ster, S., Rea, S., Taipale, M., Mendrzyk, F., Straub, B., Ittrich, C., Thuerigen, O., Sinn, H. P., Akhtar, A., and Lichter, P. (2008) The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma. Int J Cancer 122, 1207-1213. (Pubitemid 351287218)
    • (2008) International Journal of Cancer , vol.122 , Issue.6 , pp. 1207-1213
    • Pfister, S.1    Rea, S.2    Taipale, M.3    Mendrzyk, F.4    Straub, B.5    Ittrich, C.6    Thuerigen, O.7    Sinn, H.P.8    Akhtar, A.9    Lichter, P.10
  • 55
    • 33947153008 scopus 로고    scopus 로고
    • Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer
    • DOI 10.1002/ijc.22474
    • Feng, W., Lu, Z., Luo, R. Z., Zhang, X., Seto, E., Liao, W. S., and Yu, Y. (2007) Multiple histone deacetylases repress tumor suppressor gene ARHI in breast cancer. Int J Cancer 120, 1664-1668. (Pubitemid 46399351)
    • (2007) International Journal of Cancer , vol.120 , Issue.8 , pp. 1664-1668
    • Feng, W.1    Lu, Z.2    Luo, R.Z.3    Zhang, X.4    Seto, E.5    Liao, W.S.-L.6    Yu, Y.7
  • 57
    • 65649096557 scopus 로고    scopus 로고
    • Protein acetylation and histone deacetylase expression associated with malignant breast cancer progression
    • Suzuki, J., Chen, Y. Y., Scott, G. K., DeVries, S., Chin, K., Benz, C. C., Waldman, F. M., and Hwang, E. S. (2009) Protein acetylation and histone deacetylase expression associated with malignant breast cancer progression. Clin. Cancer Res. 15, 3163-3171.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 3163-3171
    • Suzuki, J.1    Chen, Y.Y.2    Scott, G.K.3    DeVries, S.4    Chin, K.5    Benz, C.C.6    Waldman, F.M.7    Hwang, E.S.8
  • 61
    • 84856221673 scopus 로고    scopus 로고
    • Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells
    • Huang, Y., Vasilatos, S. N., Boric, L., Shaw, P. G., and Davidson, N. E. (2011) Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells. Breast Cancer Res. Treat .
    • (2011) Breast Cancer Res. Treat
    • Huang, Y.1    Vasilatos, S.N.2    Boric, L.3    Shaw, P.G.4    Davidson, N.E.5
  • 62
    • 33750379420 scopus 로고    scopus 로고
    • Polycomb silencers control cell fate, development and cancer
    • DOI 10.1038/nrc1991, PII NRC1991
    • Sparmann, A. and van, L. M. (2006) Polycomb silencers control cell fate, development and cancer. Nat Rev Cancer 6, 846-856. (Pubitemid 44629896)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.11 , pp. 846-856
    • Sparmann, A.1    Van Lohuizen, M.2
  • 63
    • 23444454047 scopus 로고    scopus 로고
    • The epigenetic breakdown of cancer cells: From DNA methylation to histone modifi cations
    • Ballestar, E. and Esteller, M. (2005) The epigenetic breakdown of cancer cells: From DNA methylation to histone modifi cations. Prog Mol Subcell Biol 38, 169-181.
    • (2005) Prog. Mol. Subcell Biol. , vol.38 , pp. 169-181
    • Ballestar, E.1    Esteller, M.2
  • 65
    • 68049104358 scopus 로고    scopus 로고
    • Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning
    • Hinshelwood, R. A., Melki, J. R., Huschtscha, L. I., Paul, C., Song, J. Z., Stirzaker, C., Reddel, R. R., and Clark, S. J. (2009) Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning. Hum Mol Genet 18, 3098-3109.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 3098-3109
    • Hinshelwood, R.A.1    Melki, J.R.2    Huschtscha, L.I.3    Paul, C.4    Song, J.Z.5    Stirzaker, C.6    Reddel, R.R.7    Clark, S.J.8
  • 69
    • 10744230544 scopus 로고    scopus 로고
    • Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin
    • DOI 10.1016/S0960-9822(03)00432-9
    • Lehnertz, B., Ueda, Y., Derijck, A. A., Braunschweig, U., Perez-Burgos, L., Kubicek, S., Chen, T., Li, E., Jenuwein, T., and Peters, A. H. (2003) Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin. Curr Biol 13, 1192-1200. (Pubitemid 36872941)
    • (2003) Current Biology , vol.13 , Issue.14 , pp. 1192-1200
    • Lehnertz, B.1    Ueda, Y.2    Derijck, A.A.H.A.3    Braunschweig, U.4    Perez-Burgos, L.5    Kubicek, S.6    Chen, T.7    Li, E.8    Jenuwein, T.9    Peters, A.H.F.M.10
  • 70
    • 31444449552 scopus 로고    scopus 로고
    • Epigenetic information and estrogen receptor alpha expression in breast cancer
    • DOI 10.1634/theoncologist.11-1-1
    • Giacinti, L., Claudio, P. P., Lopez, M., and Giordano, A. (2006) Epigenetic information and estrogen receptor alpha expression in breast cancer. Oncologist 11, 1-8. (Pubitemid 43152681)
    • (2006) Oncologist , vol.11 , Issue.1 , pp. 1-8
    • Giacinti, L.1    Claudio, P.P.2    Lopez, M.3    Giordano, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.