-
1
-
-
20744439516
-
The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it
-
DOI 10.1002/dvdy.20345
-
Hay ED. The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it. Dev Dyn. 2005;233:706-20. (Pubitemid 40853448)
-
(2005)
Developmental Dynamics
, vol.233
, Issue.3
, pp. 706-720
-
-
Hay, E.D.1
-
2
-
-
84859905941
-
Sarcomatoid renal cell carcinoma may denote a biological example of epithelial to mesenchymal transition
-
Boström A-K, Möller C, Nilsson E, Elfving P, Axelson H, Johansson ME. Sarcomatoid renal cell carcinoma may denote a biological example of epithelial to mesenchymal transition. Hum Pathol. 2011.
-
(2011)
Hum Pathol.
-
-
Boström, A.-K.1
Möller, C.2
Nilsson, E.3
Elfving, P.4
Axelson, H.5
Johansson, M.E.6
-
3
-
-
0002450427
-
The transformation of a malignant paravertebral sympathicoblastoma into a benign ganglioneur-oma
-
Cushing H, Wolbach SB. The transformation of a malignant paravertebral sympathicoblastoma into a benign ganglioneur-oma. Am J Pathol. 1927;3(3):203-216.
-
(1927)
Am J Pathol.
, vol.3
, Issue.3
, pp. 203-216
-
-
Cushing, H.1
Wolbach, S.B.2
-
4
-
-
52949154642
-
High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma
-
Fredlund E, Ringner M, Maris JM, Påhlman S. High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma. Proc Natl Acad Sci USA. 2008;105:14094-9.
-
(2008)
Proc Natl Acad Sci USA.
, vol.105
, pp. 14094-14099
-
-
Fredlund, E.1
Ringner, M.2
Maris, J.M.3
Påhlman, S.4
-
5
-
-
0019468847
-
Phenotypic changes of human neuroblastoma cells in culture induced by 12-O-tetradecanoyl-phorbol-13-acetate
-
DOI 10.1002/ijc.2910280509
-
Påhlman S, Odelstad L, Larsson E, Grotte G, Nilsson K. Phenotypic changes of human neuroblastoma cells in culture induced by 12-O-tetradecanoyl- phorbol-13-acetate. Int J Cancer. 1981;28:583-9. (Pubitemid 11030489)
-
(1981)
International Journal of Cancer
, vol.28
, Issue.5
, pp. 583-589
-
-
Pahlman, S.1
Odelstad, L.2
Larsson, E.3
-
6
-
-
0019949788
-
Retinoic acid-induced growth inhibition and morphologic differentiation of human neuroblastoma cells in vitro
-
Sidell N. Retinoic acid-induced growth inhibition and morphologic differentiation of human neuroblastoma cells in vitro. J Natl Cancer Inst. 1982;68:589-96. (Pubitemid 12078843)
-
(1982)
Journal of the National Cancer Institute
, vol.68
, Issue.4
, pp. 589-596
-
-
Sidell, N.1
-
7
-
-
0028916699
-
IGF2 expression is a marker for paraganglionic/SIF cell differentiation in neuroblastoma
-
Hedborg F, Ohlsson R, Sandstedt B, Grimelius L, Hoehner JC, Påhlman S. IGF2 expression is a marker for paraganglionic/SIF cell differentiation in neuroblastoma. Am J Pathol. 1995;146:833-47.
-
(1995)
Am J Pathol.
, vol.146
, pp. 833-847
-
-
Hedborg, F.1
Ohlsson, R.2
Sandstedt, B.3
Grimelius, L.4
Hoehner, J.C.5
Påhlman, S.6
-
8
-
-
0031022022
-
In vivo spontaneous neuronal to neuroendocrine lineage conversion in a subset of neuroblastomas
-
Gestblom C, Hoehner JC, Hedborg F, Sandstedt B, Påhlman S. In vivo spontaneous neuronal to neuroendocrine lineage conversion in a subset of neuroblastomas. Am J Pathol. 1997;150:107-17. (Pubitemid 27027102)
-
(1997)
American Journal of Pathology
, vol.150
, Issue.1
, pp. 107-117
-
-
Gestblom, C.1
Hoehner, J.C.2
Hedborg, F.3
Sandstedt, B.4
Pahlman, S.5
-
9
-
-
0035925098
-
Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
-
Höckel M, Vaupel P. Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst. 2001;93:266-76. (Pubitemid 32219813)
-
(2001)
Journal of the National Cancer Institute
, vol.93
, Issue.4
, pp. 266-276
-
-
Hockel, M.1
Vaupel, P.2
-
10
-
-
0028068606
-
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
-
Semenza GL, Roth PH, Fang HM, Wang GL. Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem. 1994;269:23757-63. (Pubitemid 24293585)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.38
, pp. 23757-23763
-
-
Semenza, G.L.1
Roth, P.H.2
Fang, H.-M.3
Wang, G.L.4
-
11
-
-
76349095132
-
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
-
Semenza GL. Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene. 2010;29: 625-34.
-
(2010)
Oncogene.
, vol.29
, pp. 625-634
-
-
Semenza, G.L.1
-
12
-
-
34247477207
-
Hypoxia inducible factor-2alpha in cancer
-
Löfstedt T, Fredlund E, Holmquist-Mengelbier L, Pietras A, Ovenberger M, Poellinger L, et al. Hypoxia inducible factor-2alpha in cancer. Cell Cycle. 2007;6:919-26.
-
(2007)
Cell Cycle.
, vol.6
, pp. 919-926
-
-
Löfstedt, T.1
Fredlund, E.2
Holmquist-Mengelbier, L.3
Pietras, A.4
Ovenberger, M.5
Poellinger, L.6
-
13
-
-
0037088678
-
Modulation of basic helix-loop-helix transcription complex formation by Id proteins during neuronal differentiation
-
DOI 10.1074/jbc.M107713200
-
Jögi A, Persson P, Grynfeld A, Påhlman S, Axelson H. Modulation of basic helix-loop-helix transcription complex formation by Id proteins during neuronal differentiation. J Biol Chem. 2002;277:9118-26. (Pubitemid 34952988)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.11
, pp. 9118-9126
-
-
Jogi, A.1
Persson, P.2
Grynfeld, A.3
Pahlman, S.4
Axelson, H.5
-
14
-
-
1842861743
-
Human neuroblastoma cells exposed to hypoxia: Induction of genes associated with growth, survival, and aggressive behavior
-
DOI 10.1016/j.yexcr.2004.01.013, PII S0014482704000333
-
Jögi A, Vallon-Christersson J, Holmquist L, Axelson H, Borg A, Påhlman S. Human neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behavior. Exp Cell Res. 2004;295:469-87. (Pubitemid 38490500)
-
(2004)
Experimental Cell Research
, vol.295
, Issue.2
, pp. 469-487
-
-
Jogi, A.1
Vallon-Christersson, J.2
Holmquist, L.3
Axelson, H.4
Borg, A.5
Pahlman, S.6
-
15
-
-
78349283042
-
The HIF-2alpha-driven pseudo-hypoxic phenotype in tumor aggressiveness, differentiation, and vascularization
-
Pietras A, Johnsson AS, Påhlman S. The HIF-2alpha-driven pseudo-hypoxic phenotype in tumor aggressiveness, differentiation, and vascularization. Curr Top Microbiol Immunol. 2010;345:1-20.
-
(2010)
Curr Top Microbiol Immunol.
, vol.345
, pp. 1-20
-
-
Pietras, A.1
Johnsson, A.S.2
Påhlman, S.3
-
16
-
-
43649093915
-
Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
-
DOI 10.1016/j.molcel.2008.04.009, PII S109727650800292X
-
Kaelin WG Jr, Ratcliffe PJ. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol Cell. 2008; 30:393-402. (Pubitemid 351681994)
-
(2008)
Molecular Cell
, vol.30
, Issue.4
, pp. 393-402
-
-
Kaelin Jr., W.G.1
Ratcliffe, P.J.2
-
17
-
-
33750630119
-
Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype
-
DOI 10.1016/j.ccr.2006.08.026, PII S153561080600290X
-
Holmquist-Mengelbier L, Fredlund E, Löfstedt T, Noguera R, Navarro S, Nilsson H, et al. Recruitment of HIF-1 alpha and HIF-2 alpha to common target genes is differentially regulated in neuroblastoma: HIF-2 alpha promotes an aggressive phenotype. Cancer Cell. 2006;10:413-23. (Pubitemid 44693470)
-
(2006)
Cancer Cell
, vol.10
, Issue.5
, pp. 413-423
-
-
Holmquist-Mengelbier, L.1
Fredlund, E.2
Löfstedt, T.3
Noguera, R.4
Navarro, S.5
Nilsson, H.6
Pietras, A.7
Vallon-Christersson, J.8
Borg, A.9
Gradin, K.10
Poellinger, L.11
Pahlman, S.12
-
18
-
-
40349088993
-
High levels of HIF-2α highlight an immature neural crest-like neuroblastoma cell cohort located in a perivascular niche
-
DOI 10.1002/path.2304
-
Pietras A, Gisselsson D, Øra I, Noguera R, Beckman S, Navarro S, et al. High levels of HIF-2alpha highlight an immature neural crest-like neuroblastoma cell cohort located in a perivascular niche. J Pathol. 2008;214:482-8. (Pubitemid 351340568)
-
(2008)
Journal of Pathology
, vol.214
, Issue.4
, pp. 482-488
-
-
Pietras, A.1
Gisselsson, D.2
Ora, I.3
Noguera, R.4
Beckman, S.5
Navarro, S.6
Pahlman, S.7
-
19
-
-
73149112785
-
HIF-1alpha and HIF-2alpha are differentially regulated in vivo in neuroblastoma: High HIF-1alpha correlates negatively to advanced clinical stage and tumor vascu-larization
-
Noguera R, Fredlund E, Piqueras M, Pietras A, Beckman S, Navarro S, et al. HIF-1alpha and HIF-2alpha are differentially regulated in vivo in neuroblastoma: high HIF-1alpha correlates negatively to advanced clinical stage and tumor vascu-larization. Clin Cancer Res. 2009;15:7130-6.
-
(2009)
Clin Cancer Res.
, vol.15
, pp. 7130-7136
-
-
Noguera, R.1
Fredlund, E.2
Piqueras, M.3
Pietras, A.4
Beckman, S.5
Navarro, S.6
-
20
-
-
65749106405
-
Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
-
LiZ, Bao S, Wu Q, WangH, Eyler C, Sathornsumetee S, et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell. 2009;15:501-13.
-
(2009)
Cancer Cell.
, vol.15
, pp. 501-513
-
-
Liz Bao, S.1
Wu, Q.2
Wangh Eyler, C.3
Sathornsumetee, S.4
-
21
-
-
70349753257
-
HIF-2alpha maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells
-
Pietras A, Hansford LM, Johnsson AS, Bridges E, Sjölund J, Gisselsson D, et al. HIF-2alpha maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells. Proc Natl Acad Sci USA. 2009;106:16805-10.
-
(2009)
Proc Natl Acad Sci USA.
, vol.106
, pp. 16805-16810
-
-
Pietras, A.1
Hansford, L.M.2
Johnsson, A.S.3
Bridges, E.4
Sjölund, J.5
Gisselsson, D.6
-
22
-
-
36248949045
-
Stem cells and the stem cell niche in the breast: An integrated hormonal and developmental perspective
-
DOI 10.1007/s12015-007-0019-1, PII SCR32147
-
Brisken C, Duss S. Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective. Stem Cell Rev. 2007;3:147-56. (Pubitemid 350129717)
-
(2007)
Stem Cell Reviews
, vol.3
, Issue.2
, pp. 147-156
-
-
Brisken, C.1
Duss, S.2
-
23
-
-
0037380791
-
Hypoxia promotes a dedifferentiated phenotype in ductal breast carcinoma in situ
-
Helczynska K, Kronblad A, Jögi A, Nilsson E, Beckman S, Landberg G, et al. Hypoxia promotes a dedifferentiated phe-notype in ductal breast carcinoma in situ. Cancer Res. 2003; 63:1441-4. (Pubitemid 36373625)
-
(2003)
Cancer Research
, vol.63
, Issue.7
, pp. 1441-1444
-
-
Helczynska, K.1
Kronblad, A.2
Jogi, A.3
Nilsson, E.4
Beckman, S.5
Landberg, G.6
Pahlman, S.7
-
24
-
-
84859905946
-
-
unpublished paper
-
Vaapil et al., unpublished paper.
-
-
-
Vaapil1
-
25
-
-
84859892790
-
-
Abstract #235. AACR Annual Conference. AACR 100th Annual Meeting, Denver, Colorado, April 18-22
-
Jögi A, Helczynska K, Vaapil M, Johansson E, Beckman S, Larsson C, et al. Hypoxia impairs morphological and functional differentiation of immortalized human breast epithelial cells in 3D basement membrane matrix-culture. Abstract #235. AACR Annual Conference. AACR 100th Annual Meeting, Denver, Colorado, April 18-22. 2009.
-
(2009)
Hypoxia Impairs Morphological and Functional Differentiation of Immortalized Human Breast Epithelial Cells in 3D Basement Membrane Matrix-culture
-
-
Jögi, A.1
Helczynska, K.2
Vaapil, M.3
Johansson, E.4
Beckman, S.5
Larsson, C.6
-
26
-
-
56449095636
-
Hypoxia-inducible factor-2alpha correlates to distant recurrence and poor outcome in invasive breast cancer
-
Helczynska K, Larsson AM, Holmquist Mengelbier L, Bridges E, Fredlund E, Borgquist S, et al. Hypoxia-inducible factor-2alpha correlates to distant recurrence and poor outcome in invasive breast cancer. Cancer Res. 2008;68:9212-20.
-
(2008)
Cancer Res.
, vol.68
, pp. 9212-9220
-
-
Helczynska, K.1
Larsson, A.M.2
Holmquist Mengelbier, L.3
Bridges, E.4
Fredlund, E.5
Borgquist, S.6
-
27
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
DOI 10.1073/pnas.0530291100
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA. 2003;100: 3983-8. (Pubitemid 36418143)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
28
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
DOI 10.1016/j.cell.2008.03.027, PII S0092867408004443
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 2008;133: 704-15. (Pubitemid 351636299)
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.-J.3
Eaton, E.Ng.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
29
-
-
68949204214
-
Oxygen regulates epithelial-to-mesenchymal transition: Insights into molecular mechanisms and relevance to disease
-
Haase VH. Oxygen regulates epithelial-to-mesenchymal transition: insights into molecular mechanisms and relevance to disease. Kidney Int. 2009;76:492-9.
-
(2009)
Kidney Int.
, vol.76
, pp. 492-499
-
-
Haase, V.H.1
-
30
-
-
0029852033
-
A developmental model of neuroblastoma: Differentiating stroma-poor tumors' progress along an extra-adrenal chromaffin lineage
-
Hoehner JC, Gestblom C, Hedborg F, Sandstedt B, Olsen L, Påhlman S. A developmental model of neuroblastoma: differentiating stroma-poor tumors' progress along an extra-adrenal chromaffin lineage. Lab Invest. 1996;75:659-75. (Pubitemid 26392797)
-
(1996)
Laboratory Investigation
, vol.75
, Issue.5
, pp. 659-675
-
-
Hoehner, J.C.1
Gestblom, C.2
Hedborg, F.3
Sandstedt, B.4
Olsen, L.5
Pahlman, S.6
-
31
-
-
0019403511
-
Neuron-specific enolase in relation to differentiation in human neuroblastoma
-
DOI 10.1016/0006-8993(81)91117-3
-
Odelstad L, Pahlman S, Nilsson K, Larsson E, Lackgren G, Johansson KE, et al. Neuron-specific enolase in relation to differentiation in human neuroblastoma. Brain Res. 1981;224: 69-82. (Pubitemid 11008167)
-
(1981)
Brain Research
, vol.224
, Issue.1
, pp. 69-82
-
-
Odelstad, L.1
Pahlman, S.2
Nilsson, K.3
-
32
-
-
33845610993
-
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
-
DOI 10.1038/nature05349, PII NATURE05349
-
Piccirillo SG, Reynolds BA, Zanetti N, Lamorte G, Binda E, Broggi G, et al. Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells. Nature. 2006;444:761-5. (Pubitemid 44949605)
-
(2006)
Nature
, vol.444
, Issue.7120
, pp. 761-765
-
-
Piccirillo, S.G.M.1
Reynolds, B.A.2
Zanetti, N.3
Lamorte, G.4
Binda, E.5
Broggi, G.6
Brem, H.7
Olivi, A.8
Dimeco, F.9
Vescovi, A.L.10
-
33
-
-
37349067098
-
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells
-
DOI 10.1016/j.ccr.2007.12.005, PII S1535610807003741
-
Lee J, Son MJ, Woolard K, Donin NM, Li A, Cheng CH, et al. Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells. Cancer Cell. 2008;13: 69-80. (Pubitemid 350309742)
-
(2008)
Cancer Cell
, vol.13
, Issue.1
, pp. 69-80
-
-
Lee, J.1
Son, M.J.2
Woolard, K.3
Donin, N.M.4
Li, A.5
Cheng, C.H.6
Kotliarova, S.7
Kotliarov, Y.8
Walling, J.9
Ahn, S.10
Kim, M.11
Totonchy, M.12
Cusack, T.13
Ene, C.14
Ma, H.15
Su, Q.16
Zenklusen, J.C.17
Zhang, W.18
Maric, D.19
Fine, H.A.20
more..
|