Ochratoxin A induces oxidative DNA damage and G1 phase arrest in human peripheral blood mononuclear cells in vitro

Toxicology Letters

Volumn 211, Issue 2, 2012, Pages 164-171

  Liu, Jing ^a   Wang, Yuan ^a   Cui, Jinfeng ^a   Xing, Lingxiao ^a   Shen, Haitao ^a   Wu, Sha ^a   Lian, Hongguang ^a   Wang, Junling ^a   Yan, Xia ^a   Zhang, Xianghong ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Cell cycle arrest; DNA damage; Human peripheral blood mononuclear cells; Ochratoxin A; Reactive oxygen species

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ACETYLCYSTEINE; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; GLUTATHIONE; HISTONE H2AX; HYDROPEROXIDE; OCHRATOXIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA STRAND BREAKAGE; DOWN REGULATION; GENOTOXICITY; HUMAN; HUMAN CELL; IMMUNOTOXICITY; IN VITRO STUDY; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEADY STATE; TOXICITY TESTING;

ACETYLCYSTEINE; ANTIOXIDANTS; APOPTOSIS; CYCLIN D1; CYCLIN-DEPENDENT KINASE 4; DEOXYGUANOSINE; DNA DAMAGE; G1 PHASE CELL CYCLE CHECKPOINTS; GLUTATHIONE; HUMANS; LEUKOCYTES, MONONUCLEAR; OCHRATOXINS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84859925663     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.03.800     Document Type: Article

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