Role of fractalkine/CX3CR1 interaction in light-induced photoreceptor degeneration through regulating retinal microglial activation and migration

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Zhang, Meng ^a   Xu, Gezhi ^a,b   Liu, Wei ^a   Ni, Yingqin ^a   Zhou, Wenting ^a  

^a EYE AND ENT HOSPITAL OF FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CX3CR1; CX3CR1 ANTIBODY; CYTOKINE; FRACTALKINE; NEUTRALIZING ANTIBODY; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; CHEMOKINE RECEPTOR; CX3CL1 PROTEIN, RAT; CX3CR1 PROTEIN, RAT; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLUE LIGHT; CELL COUNT; CELL MIGRATION; CHEMOTAXIS; COCULTURE; CONTROLLED STUDY; DEGENERATION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; IN VIVO STUDY; LIGHT EXPOSURE; MALE; MICROGLIA; NERVE CELL STIMULATION; NEWBORN; NICK END LABELING; NONHUMAN; PHOTORECEPTOR CELL; PHOTORECEPTOR DEGENERATION; PHOTOSTIMULATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; REGULATORY MECHANISM; RETINA NERVE CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL MOTION; CELL SHAPE; GENETICS; LIGHT; METABOLISM; PATHOLOGY; PHYSIOLOGY; RADIATION EXPOSURE; RETINA; RETINA DEGENERATION; SECRETION; SPRAGUE DAWLEY RAT; UPREGULATION;

RATTUS;

ANIMALS; APOPTOSIS; CELL MOVEMENT; CELL SHAPE; CELLS, CULTURED; CHEMOKINE CX3CL1; COCULTURE TECHNIQUES; INTERLEUKIN-1BETA; LIGHT; MICROGLIA; PHOTORECEPTOR CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CHEMOKINE; RETINA; RETINAL DEGENERATION; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84859812528     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035446     Document Type: Article

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