Activation of microglia and chemokines in light-induced retinal degeneration

Molecular Vision

Volumn 11, Issue , 2005, Pages 887-895

  Zhang, Cheng ^a   Shen, Ji Kui ^a   Lam, Tim T ^b,c   Zeng, Hui Yang ^a,d   Chiang, Samuel K ^a   Yang, Fang ^a   Tso, Mark O M ^a,d  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c Bausch and Lomb ^*  (United States)

^d PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR5; DNA FRAGMENT; DNA NUCLEOTIDYLEXOTRANSFERASE; ERYTHROPOIETIN; LECTIN; MESSENGER RNA; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL COUNT; CELL LABELING; CELL MIGRATION; CELL STRUCTURE; CONTROLLED STUDY; DARK ADAPTATION; GENE EXPRESSION; LIGHT EXPOSURE; MALE; MICROGLIA; MOUSE; MOUSE STRAIN; NERVE CELL STIMULATION; NICK END LABELING; NONHUMAN; PHOTORECEPTOR; PHOTORECEPTOR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA CELL; RETINA DEGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANTIGENS, CD11B; CELL MOVEMENT; CHEMOKINES; GENE EXPRESSION REGULATION; GLYCOPROTEINS; IMMUNOENZYME TECHNIQUES; IN SITU NICK-END LABELING; LIGHT; MALE; MICE; MICE, INBRED BALB C; MICROGLIA; RADIATION INJURIES, EXPERIMENTAL; RECEPTORS, CHEMOKINE; RETINA; RETINAL DEGENERATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION;

EID: 27744557317     PISSN: 10900535     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Thanos S. Sick photoreceptors attract activated microglia from the ganglion cell layer: a model to study the inflammatory cascades in rats with inherited retinal dystrophy. Brain Res 1992; 588:21-8.
2. Thanos S, Richter W. The migratory potential of vitally labelled microglial cells within the retina of rats with hereditary photoreceptor dystrophy. Int J Dev Neurosci 1993; 11:671-80.
3. Roque RS, Imperial CJ, Caldwell RB. Microglial cells invade the outer retina as photoreceptors degenerate in Royal College of Surgeons rats. Invest Ophthalmol Vis Sci 1996; 37:196-203.
4. Ng TF, Streilein JW. Light-induced migration of retinal microglia into the subretinal space. Invest Ophthalmol Vis Sci 2001: 42:3301-10.
5. Noell WK. Possible mechanisms of photoreceptor damage by light in mammalian eyes. Vision Res 1980; 20:1163-71.
6. Ransohoff RM, Tani M. Do chemokines mediate leukocyte recruitment in post-traumatic CNS inflammation? Trends Neurosci 1998: 21:154-9.
7. Askovic S, Favara C, McAtee FJ, Portis JL. Increased expression of MIP-1 alpha and MIP-1 beta mRNAs in the brain correlates spatially and temporally with the spongiform neurodegeneration induced by a murine oncornavirus. J Virol 2001; 75:2665-74.
8. Flugel A, Hager G, Horvat A, Spitzer C, Singer GM, Graeber MB, Kreutzberg GW, Schwaiger FW. Neuronal MCP-1 expression in response to remote nerve injury. J Cereb Blood Flow Metab 2001; 21:69-76.
9. Tuaillon N, Shen de F, Berger RB, Lu B, Rollins BJ, Chan CC. MCP-1 expression in endotoxin-induced uveitis. Invest Ophthalmol Vis Sci 2002; 43:1493-8.
10. Streit WJ, Conde JR, Harrison JK. Chemokines and Alzheimer's, disease. Neurobiol Aging 2001; 22:909-13,
11. Wang X, Li X, Yaish-Ohad S, Saran HM, Barone FC, Feuerstein GZ. Molecular cloning and expression of the rat monocyte chemotactic protein-3 gene: a possible role in stroke. Brain Res Mol Brain Res 1999; 71:304-12.
12. Rollins BJ. Chemokines. Blood 1997; 90:909-28.
13. Wu T, Chen Y, Chiang SK, Tso MO. NF-kappaB activation in light-induced retinal degeneration in a mouse model. Invest Ophthalmol Vis Sci 2002; 43:2834-40.
14. Zhang C, Lei B, Lam TT. Yang F, Sinha D, Tso MO. Neuroprotection of photoreceptors by minocycline in light-induced retinal degeneration. Invest Ophthalmol Vis Sci 2004: 45:2753-9
15. Tso MO, Zhang C, Abler AS, Chang CJ, Wong F, Chang GQ, Lam TT. Apoptosis leads to photoreceptor degeneration in inherited retinal dystrophy of RCS rats. Invest Ophthalmol Vis Sci 1994; 35:2693-9.
16. Abler AS, Chang CJ, Ful J, Tso MO, Lam TT. Photic injury triggers apoptosis of photoreceptor cells. Res Commun Mol Pathol Pharmacol 1996; 92:177-89.
17. Li S, Chang CJ, Abler AS, Fu J, Tso MO. Lam TT. A comparison of continuous versus intermittent light exposure on apoptosis. Curr Eye Res 1996; 15:914-22.
18. Gebicke-Haerter PJ. Microglia in neurodegeneration: molecular aspects. Microsc Res Tech 2001; 54:47-58.
19. Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 1996: 19:312-8.
20. McGeer PL, McGeer EG. The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases. Brain Res Brain Res Rev 1995; 21:195-218.
21. Streit WJ, Kreutzberg GW. Lectin binding by resting and reactive microglia. J Neurocytol 1987: 16:249-60.
22. Bertolotto A, Caterson B, Canavese G, Migheli A, Schiffer D. Monoclonal antibodies to keratan sulfate immunolocalize ramified microglia in paraffin and cryostat sections of rat brain. J Histochem Cytochem 1993; 41:481-7.
23. Jander S, Stoll G. Strain-specific expression of microglial keratan sulfate proteoglycans in the normal rat central nervous system: inverse correlation with constitutive expression of major histocompatibility complex class II antigens. Glia 1996; 18:255-60.
24. Akaishi K, Ishiguro S, Durlu YK, Tamai M. Quantitative analysis of major histocompatibility complex class II-positive cells in posterior segment of Royal College of Surgeons rat eyes. Jpn J Ophthalmol 1998; 42:357-62.
25. Moore S, Thanos S. The concept of microglia in relation to central nervous system disease and regeneration. Prog Neurobiol 1996; 48:441-60.
26. Van Damme J, Proost P, Lenaerts JP, Opdenakker G. Structural and functional identification of two human, tumor-derived monocyte chemotactic proteins (MCP-2 and MCP-3) belonging to the chemokine family. J Exp Med 1992; 176:59-65.
27. Sozzani S, Locati M, Zhou D, Rieppi M, Luini W, Lamorte G, Bianchi G, Polentarutti N, Allavena P, Mantovani A. Receptors, signal transduction, and spectrum of action of monocyte chemotactic protein-1 and related chemokines. J Leukoc Biol 1995; 57:788-94.
28. Berman JW, Guida MP, Warren J, Amat J, Brosnan CF. Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat. J Immunol 1996; 156:3017-23.
29. Ivacko J, Szaflarski J, Malinak C, Flory C, Warren JS, Silverstein FS. Hypoxic-ischemic injury induces monocyte chemoattractant protein-1 expression in neonatal rat brain. J Cereb Blood Flow Metab 1997; 17:759-70.
30. Ishizuka K, Kimura T, Igata-yi R, Katsuragi s, Takamatsu J, Miyakawa T. Identification of monocyte chemoattractant protein-1 in senile plaques and reactive microglia of Alzheimer's disease. Psychiatry Clin Neurosci 1997; 51:135-8.
31. Szaflarski J, Ivacko J, Liu XH, Warren JS, Silverstein FS. Excitotoxic injury induces monocyte chemoattractant protein-1 expression in neonatal rat brain. Brain Res Mol Brain Res 1998; 55:306-14.
32. McManus C, Berman JW, Brett FM, Staunton H, Farrell M, Brosnan CF. MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study. J Neuroimmunol 1998; 86:20-9.