Role of the chemokine receptor CX3CR1 in the mobilization of phagocytic retinal microglial cells

Journal of Neuroimmunology

Volumn 198, Issue 1-2, 2008, Pages 56-61

  Raoul, William ^a,b,c   Keller, Nicole ^a,b,c   Rodéro, Mathieu ^b,d   Behar Cohen, Francine ^a,b,c,e   Sennlaub, Florian ^a,b,c   Combadière, Christophe ^b,d,f  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d INSERM   (France)

^e HÔTEL DIEU   (France)

^f ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR1; RHODOPSIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROL GROUP; CONTROLLED STUDY; LIGHT EXPOSURE; MICROGLIA; MOUSE; NONHUMAN; PHAGOCYTE; PHOTORECEPTOR; PRIORITY JOURNAL; RAT; RETINA CELL; RETINA MACULA DEGENERATION; RETINA ROD OUTER SEGMENT;

ANIMALS; CELL MOVEMENT; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; LIGHT; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; MICROSCOPY, ELECTRON, TRANSMISSION; PHAGOCYTES; PHAGOCYTOSIS; PHOTORECEPTORS; RECEPTORS, CHEMOKINE; RETINA; RETINAL DEGENERATION; RHODOPSIN; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 48949116059     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2008.04.014     Document Type: Article

References (15)

1. Ambati J., Anand A., Fernandez S., Sakurai E., Lynn B.C., Kuziel W.A., Rollins B.J., and Ambati B.K. An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice. Nat. Med. 9 (2003) 1390-1397
2. Bird A.C., Bressler N.M., Bressler S.B., Chisholm I.H., Coscas G., Davis M.D., de Jong P.T., Klaver C.C., Klein B.E., Klein R., et al. An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv. Ophthalmol. 39 (1995) 367-374
3. Checchin D., Sennlaub F., Levavasseur E., Leduc M., and Chemtob S. Potential role of microglia in retinal blood vessel formation. Investig. Ophthalmol. Vis. Sci. 47 (2006) 3595-3602
4. Combadière C., Feumi C., Raoul W., Keller N., Rodéro M., Pézard A., Lavalette S., Houssier M., Jonet L., Picard E., Debré P., Sirinyan M., Deterre P., Ferroukhi T., Cohen S., Chauvaud D., Jeanny J.-C., Chemtob S., Behar-Cohen F., and Sennlaub F. CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration. J. Clin. Invest. 117 10 (2007) 2920-2928
5. Combadiere C., Potteaux S., Gao J.L., Esposito B., Casanova S., Lee E.J., Debre P., Tedgui A., Murphy P.M., and Mallat Z. Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice. Circulation 107 (2003) 1009-1016
6. Friedman D.S., O'Colmain B.J., Munoz B., Tomany S.C., McCarty C., de Jong P.T., Nemesure B., Mitchell P., and Kempen J. Prevalence of age-related macular degeneration in the United States. Arch. Ophthalmol. 122 (2004) 564-572
7. Gupta N., Brown K.E., and Milam A.H. Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and age-related macular degeneration. Exp. Eye Res. 76 (2003) 463-471
8. Jung S., Aliberti J., Graemmel P., Sunshine M.J., Kreutzberg G.W., Sher A., and Littman D.R. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol. Cell. Biol. 20 (2000) 4106-4114
9. Luster A.D. Chemokines-chemotactic cytokines that mediate inflammation. N. Engl. J. Med. 338 (1998) 436-445
10. Ng T.F., and Streilein J.W. Light-induced migration of retinal microglia into the subretinal space. Investig. Ophthalmol. Vis. Sci. 42 (2001) 3301-3310
11. Pham V.T., Wen L., McCluskey P., Madigan M.C., and Penfold P.L. Human retinal microglia express candidate receptors for HIV-1 infection. Br. J. Ophthalmol. 89 (2005) 753-757
12. Ransohoff R.M., Liu L., and Cardona A.E. Chemokines and chemokine receptors: multipurpose players in neuroinflammation. Int. Rev. Neurobiol. 82 (2007) 187-204
13. Roque R.S., Imperial C.J., and Caldwell R.B. Microglial cells invade the outer retina as photoreceptors degenerate in Royal College of Surgeons rats. Investig. Ophthalmol. Vis. Sci. 37 (1996) 196-203
14. Sarks S.H. Ageing and degeneration in the macular region: a clinico-pathological study. Br. J. Ophthalmol. 60 (1976) 324-341
15. Tso M.O., Zhang C., Abler A.S., Chang C.J., Wong F., Chang G.Q., and Lam T.T. Apoptosis leads to photoreceptor degeneration in inherited retinal dystrophy of RCS rats. Investig. Ophthalmol. Vis. Sci. 35 (1994) 2693-2699