Cardiac lineage protein-1 (CLP-1) regulates cardiac remodeling via transcriptional modulation of diverse hypertrophic and fibrotic responses and angiotensin II-transforming growth factor β (TGF-β1) signaling axis

Journal of Biological Chemistry

Volumn 287, Issue 16, 2012, Pages 13084-13093

  Mascareno, Eduardo ^a   Galatioto, Josephine ^a   Rozenberg, Inna ^a   Salciccioli, Louis ^b   Kamran, Haroon ^b   Lazar, Jason M ^b   Liu, Fang ^c   Pedrazzini, Thierry ^d   Siddiqui, M A Q ^a  

^a SUNY Downstate Medical Center   (United States)

^b SUNY DOWNSTATE MEDICAL CENTER   (United States)

^c RUTGERS UNIVERSITY   (United States)

^d University of Lausanne Medical Center   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ATRIAL NATRIURETIC PEPTIDES; CARBOXYL-TERMINAL DOMAIN; CARDIAC REMODELING; COLLAGEN EXPRESSION; COLLAGEN SYNTHESIS; EXTRACELLULAR MATRIX DEPOSITION; GENETIC RESPONSE; GROWTH FACTOR; HETEROZYGOSITY; IN-VIVO; LEFT VENTRICULAR HYPERTROPHIES; MYOFIBROBLASTS; NUCLEAR LOCALIZATION; RENIN-ANGIOTENSIN SYSTEM; RNA POLYMERASE II; SERINE KINASE; SERINE RESIDUES; TRANSCRIPTIONAL MODULATION; TRANSGENIC MICE; TRANSGENICS;

ACTIVATION ANALYSIS; AMINO ACIDS; CELL CULTURE; COLLAGEN; ENZYME INHIBITION; FIBROBLASTS; MAMMALS; PATHOLOGY; PHOSPHORYLATION; RNA; SIGNALING;

PLANTS (BOTANY);

ANGIOTENSIN II; ANGIOTENSINOGEN; CARDIAC LINEAGE PROTEIN 1; MYOSIN HEAVY CHAIN ALPHA; SMAD3 PROTEIN; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE OVEREXPRESSION; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE FIBROSIS; HETEROZYGOTE; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE;

ANGIOTENSIN II; ANGIOTENSINOGEN; ANIMALS; CARDIOMEGALY; EXTRACELLULAR MATRIX; FIBROBLASTS; FIBROSIS; HETEROZYGOTE; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYOSIN HEAVY CHAINS; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA1; VENTRICULAR REMODELING;

MUS; MUS MUSCULUS;

EID: 84859776127     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.288944     Document Type: Article

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