Inhibition of Jak2 phosphorylation attenuates pressure overload cardiac hypertrophy

Vascular Pharmacology

Volumn 45, Issue 6, 2006, Pages 350-357

  Beckles, Daniel L ^a   Mascareno, Eduardo ^a   Siddiqui, M A Q ^a  

^a SUNY Downstate Medical Center   (United States)

Author keywords

Hypertrophy; Jak Stat pathway; Pressure overload hypertrophy; Signal transduction

Indexed keywords

ALPHA ACTIN; ATRIAL NATRIURETIC FACTOR; COLLAGEN; JANUS KINASE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MKP 1 PHOSPHATASE; MOLECULAR MARKER; MYOSIN HEAVY CHAIN BETA; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHOSPHATASE; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HEART LEFT VENTRICLE MASS; HEART LEFT VENTRICLE OVERLOAD; HEART VENTRICLE HYPERTROPHY; HISTOPATHOLOGY; IN VIVO STUDY; M MODE ECHOCARDIOGRAPHY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TWO DIMENSIONAL ECHOCARDIOGRAPHY;

ACTINS; ANIMALS; AORTA, THORACIC; ATRIAL NATRIURETIC FACTOR; BLOOD PRESSURE; CARDIOMEGALY; DISEASE MODELS, ANIMAL; ECHOCARDIOGRAPHY; HEART VENTRICLES; JANUS KINASE 2; LIGATION; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RNA, MESSENGER; STAT3 TRANSCRIPTION FACTOR; TYRPHOSTINS; VENTRICULAR FUNCTION, LEFT; VENTRICULAR MYOSINS; VENTRICULAR REMODELING;

EID: 33751116837     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2006.05.006     Document Type: Article

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