Increased cardiac angiotensin II levels induce right and left ventricular hypertrophy in normotensive mice

Hypertension

Volumn 35, Issue 4, 2000, Pages 985-991

  Mazzolai, Lucia ^a   Pedrazzini, Thierry ^a   Nicoud, Françoise ^a   Gabbiani, Giulio ^b   Brunner, Hans R ^a   Nussberger, Jürg ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Angiotensin I; Angiotensin II; Angiotensin converting enzyme inhibitors; Blood pressure; Fibrosis; Receptors; Renin

Indexed keywords

ANGIOTENSIN;

ANGIOTENSIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; HEART LEFT VENTRICLE HYPERTROPHY; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TISSUE LEVEL;

EID: 0034024638     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.35.4.985     Document Type: Article

References (21)

1. Reid IA, Morris BJ, Ganong WJ. The renin-angiotensin system. Ann Rev Physiol. 1978;40:377-410.
2. Gunning ME, Ingelfinger JR, King AJ, Brenner BM. Vasoactive peptide and the kidney. In: Brenner BM, ed. The Kidney. Philadelphia, Pa: WB Saunders Co; 1996:627-712.
3. Mazzolai L, Nussberger J, Aubert J, Brunner D, Brunner H, Pedrazzini T. Blood pressure independent cardiac hypertrophy induced by locally activated renin-angiotensin system. Hypertension. 1998;31:1324-1330.
4. Schunkert H, Sadoshima JI, Cornelius T, Kagaya Y, Weinberg EO, Izumo S, Riegger G, Lorell BH. Angiotensin II-induced growth responses in isolated adult rat hearts: evidence for load-independent induction of cardiac protein synthesis by angiotensin II. Circ Res. 1995;76:489-497.
5. Baker KM, Aceto JF. Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells. Am J Physiol. 1990;259:H610-H618.
6. Oparil S, Erinoff L, Cutilletta A. Catecholamines, blood pressure, renin and myocardial function in the spontaneously hypertensive rat. Clin Sci Mol Med. 1976;3:445s-459s.
7. Sen S, Tarazi RC, Khairallah PA, Bumpus FM. Cardiac hypertrophy in spontaneously hypertensive rats. Circ Res. 1974;35:775-781.
8. Pfeffer JM, Pfeffer MA, Mirsky I, Braunwald E. Progression of left ventricular hypertrophy and prevention of left ventricular dysfunction by captopril in the spontaneously hypertensive rat. Proc Natl Acad Sci U S A. 1982;79:3310-3314.
9. Rockman HA, Wachhorst SP, Mao L, Ross J Jr. Ang II receptor blockade prevents ventricular hypertrophy and ANF gene expression with pressure overload in mice. Am J Physiol. 1994;266:H2468-H2475.
10. Grimm D, Kromer EP, Bocker W, Bruckschlegel G, Holmer S, Riegger GAJ, Schunkert H. Regulation of extracellular matrix proteins in pressure-overload cardiac hypertrophy: effects of angiotensin converting enzyme inhibition. J Hypertens. 1998;16:1345-1355.
11. Nussberger J, Brunner DB, Waeber B, Brunner HR. True versus immunoreactive angiotensin II in human plasma. Hypertension. 1985;7(suppl I):I-1-I-7.
12. Skalli O, Ropraz P, Trzeciak A, Benzonana G, Gillessen D, Gabbiani G. A monoclonal antibody against α-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol. 1986;103:2787-2796.
13. Unger T, Culman J, Gohlke P. Angiotensin II receptor blockade and end-organ protection: pharmacological rationale and evidence. J Hypertens. 1999;16:S3-S9.
14. Campbell DJ, Kladis A, Valentijn AJ. Effects of losartan on angiotensin and bradykinin peptides and angiotensin-converting enzyme. J Cardiovasc Pharmacol. 1995;26:233-240.
15. de Lannoy LM, Danser AHJ, Bouhuizen AMB, Saxena PR, Schalekamp MADH. Localization and production of angiotensin II in the isolated perfused rat heart. Hypertension. 1998;31:1111-1117.
16. Weber KT, Brilla CG. Myocardial fibrosis and the renin-angiotensin-aldosterone system. J Cardiovasc Pharmacol. 1992;20(suppl I):48-54.
17. Zhou G, Kandala JC, Tyagi SC, Katwa LC, Weber KT. Effects of angiotensin II and aldosterone on collagen gene expression and protein turnover in cardiac fibroblasts. Mol Cell Biochem. 1996;154:171-178.
18. Flesch M, Schiffer F, Zolk O, Pinto YM, Rosenkranz S, Hirth-Dietrich C, Arnold G, Paul M, Böhm M. Contractile systolic and diastolic dysfunction in renin-induced hypertensive cardiomyopathy. Hypertension. 1997;30:383-391.
19. Bohlender J, Fukamizu A, Lippoldt A, Nomura T, Dietz R, Menard J, Murakami K, Luft FC, Ganten D. High human renin hypertension in transgenic rats. Hypertension. 1997;29:428-434.
20. Geisterfer AAT, Christe M, Conner DA, Ingwall JS, Schoen FJ, Seidman CE, Seidman JG. A mouse model of familial hypertrophic cardiomyopathy. Science. 1996;272:731-734.
21. Bryant D, Becker L, Richardson J, Shelton J, Franco F, Peshock R, Thompson M, Giroir B. Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha. Circulation. 1998;97:1375-1381.