Erratum: Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients (Neuropsychopharmacology (2012) 37, (1455-1464) DOI: 10.1038/npp.2011.331);Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients

Neuropsychopharmacology

Volumn 37, Issue 6, 2012, Pages 1455-1464

  Menke, Andreas ^a   Arloth, Janine ^a   Pütz, Benno ^a   Weber, Peter ^a   Klengel, Torsten ^a   Mehta, Divya ^a   Gonik, Mariya ^a   Rex Haffner, Monika ^a   Rubel, Jennifer ^a   Uhr, Manfred ^a   Lucae, Susanne ^a   Deussing, Jan M ^a,b   Müller Myhsok, Bertram ^a   Holsboer, Florian ^a   Binder, Elisabeth B ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

dexamethasone; FKBP5; gene expression; glucocorticoid receptor; major depression; RNA

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; MOLECULAR MARKER;

ADULT; ARTICLE; BLOOD CELL; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE CLASSIFICATION; GENE EXPRESSION REGULATION; GENOME; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MAJOR DEPRESSION; MALE; PRIORITY JOURNAL; RANDOM FOREST; SENSITIVITY ANALYSIS; TRANSCRIPTION REGULATION;

EID: 84859769789     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.21     Document Type: Erratum

References (60)

1. Anacker C, Zunszain PA, Cattaneo A, Carvalho LA, Garabedian MJ, Thuret S et al (2011). Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor. Mol Psychiatry 16: 738-750.
2. Binder EB (2009). The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. Psychoneuroendocrinology 34(Suppl 1): S186-S195.
3. Blaveri E, Kelly F, Mallei A, Harris K, Taylor A, Reid J et al (2010). Expression profiling of a genetic animal model of depression reveals novel molecular pathways underlying depressive-like behaviours. PLoS One 5: e12596.
4. Borovecki F, Lovrecic L, Zhou J, Jeong H, Then F, Rosas HD et al (2005). Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease. Proc Natl Acad Sci USA 102: 11023-11028. (Pubitemid 41105986)
5. Breiman L (2001). Random Forests. Machine Learning 45: 5-32. (Pubitemid 32933532)
6. Carvalho LA, Pariante CM (2008). In vitro modulation of the glucocorticoid receptor by antidepressants. Stress 11: 411-424.
7. Czock D, Keller F, Rasche FM, Haussler U (2005). Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids. Clin Pharmacokinet 44: 61-98. (Pubitemid 40096038)
8. Dumeaux V, Lund E, Borresen-Dale A-L (2008). Comparison of globin RNA processing methods for genome-wide transcriptome analysis from whole blood. Biomark Med 2: 11-21. (Pubitemid 351445076)
9. Dunning MJ, Smith ML, Ritchie ME, Tavare S (2007). Beadarray: R classes and methods for Illumina bead-based data. Bioinformatics 23: 2183-2184. (Pubitemid 47394121)
10. Duric V, Banasr M, Licznerski P, Schmidt HD, Stockmeier CA, Simen AA et al (2010). A negative regulator of MAP kinase causes depressive behavior. Nat Med 16: 1328-1332.
11. Expression Analysis (2007). http://www.expressionanalysis.com/pdf/ IlluminaBlood-TechNote-2007.pdf.
12. Funato H, Kobayashi A, Watanabe Y (2006). Differential effects of antidepressants on dexamethasone-induced nuclear translocation and expression of glucocorticoid receptor. Brain Res 1117: 125-134. (Pubitemid 44573106)
13. Gerhold DL, Jensen RV, Gullans SR (2002). Better therapeutics through microarrays. Nat Genet 32(Suppl): 547-551.
14. Gladkevich A, Kauffman HF, Korf J (2004). Lymphocytes as a neural probe: potential for studying psychiatric disorders. Prog Neuropsychopharmacol Biol Psychiatry 28: 559-576. (Pubitemid 38490769)
15. Gormley GJ, Lowy MT, Reder AT, Hospelhorn VD, Antel JP, Meltzer HY (1985). Glucocorticoid receptors in depression: relationship to the dexamethasone suppression test. Am J Psychiatry 142: 1278-1284. (Pubitemid 16216563)
16. Heiske A, Jesberg J, Krieg JC, Vedder H (2003). Differential effects of antidepressants on glucocorticoid receptors in human primary blood cells and human monocytic U-937 cells. Neuropsychopharmacology 28: 807-817.
17. Hery M, Semont A, Fache MP, Faudon M, Hery F (2000). The effects of serotonin on glucocorticoid receptor binding in rat raphe nuclei and hippocampal cells in culture. J Neurochem 74: 406-413. (Pubitemid 30012795)
18. Holsboer F (2000). The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology 23: 477-501.
19. Holsboer F (2008). How can we realize the promise of personalized antidepressant medicines? Nat Rev Neurosci 9: 638-646.
20. Huber W, von Heydebreck A, Sultmann H, Poustka A, Vingron M (2002). Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics 18(Suppl 1): S96-104. (Pubitemid 41185642)
21. Ising M, Horstmann S, Kloiber S, Lucae S, Binder EB, Kern N et al (2007). Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depressionFa potential biomarker? Biol Psychiatry 62: 47-54. (Pubitemid 46898222)
22. Ising M, Lucae S, Binder EB, Bettecken T, Uhr M, Ripke S et al (2009). A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Arch Gen Psychiatry 66: 966-975.
23. Jääskeläinen T, Makkonen H, Palvimo JJ (2011). Steroid upregulation of FKBP51 and its role in hormone signaling. Curr Opin Pharmacol 11: 326-331 (in press).
24. Kitchen RR, Sabine VS, Sims AH, Macaskill EJ, Renshaw L, Thomas JS et al (2010). Correcting for intra-experiment variation in Illumina BeadChip data is necessary to generate robust geneexpression profiles. BMC Genomics 11: 134.
25. Kunzel HE, Binder EB, Nickel T, Ising M, Fuchs B, Majer M et al (2003). Pharmacological and nonpharmacological factors influencing hypothalamic- pituitary-adrenocortical axis reactivity in acutely depressed psychiatric in-patients, measured by the Dex-CRH test. Neuropsychopharmacology 28: 2169-2178. (Pubitemid 37468184)
26. Kurian SM, Le-Niculescu H, Patel SD, Bertram D, Davis J, Dike C et al (2011). Identification of blood biomarkers for psychosis using convergent functional genomics. Mol Psychiatry 16: 37-58.
27. Lai M, McCormick JA, Chapman KE, Kelly PA, Seckl JR, Yau JL (2003). Differential regulation of corticosteroid receptors by monoamine neurotransmitters and antidepressant drugs in primary hippocampal culture. Neuroscience 118: 975-984. (Pubitemid 36561186)
28. Landmann R, Schaub B, Link S, Wacker HR (1997). Unaltered monocyte function in patients with major depression before and after three months of antidepressive therapy. Biol Psychiatry 41: 675-681. (Pubitemid 27157759)
29. Le-Niculescu H, Kurian SM, Yehyawi N, Dike C, Patel SD, Edenberg HJ et al (2009). Identifying blood biomarkers for mood disorders using convergent functional genomics. Mol Psychiatry 14: 156-174.
30. Liaw A, Wiener M (2002). Classification and Regression by randomForest. R News 2: 18-22.
31. Lowy MT, Reder AT, Gormley GJ, Meltzer HY (1988). Comparison of in vivo and in vitro glucocorticoid sensitivity in depression: relationship to the dexamethasone suppression test. Biol Psychiatry 24: 619-630.
32. Mehta D (2008). GlobinFto reduce or not to reduce. Personal Communication.
33. Mehta D, Gonik M, Klengel T, Rex-Haffner M, Menke A, Rubel J et al (2011). Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from Endocrine and Gene Expression Studies. Arch Gen Psychiatry 68: 901-910.
34. Mehta D, Menke A, Binder EB (2010). Gene expression studies in major depression. Curr Psychiatry Rep 12: 135-144.
35. Menke A, Rex-Haffner M, Klengel T, Binder B, Mehta D (2011). Peripheral blood gene expression: it all boils down to the RNA collection tubes. BMC Res Notes (in press).
36. Ozcift A (2011). Random forests ensemble classifier trained with data resampling strategy to improve cardiac arrhythmia diagnosis. Comput Biol Med 41: 265-271.
37. Padmos RC, Hillegers MH, Knijff EM, Vonk R, Bouvy A, Staal FJ et al (2008). A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes. Arch Gen Psychiatry 65: 395-407. (Pubitemid 351519889)
38. Pariante CM (2009). Risk factors for development of depression and psychosis. Glucocorticoid receptors and pituitary implications for treatment with antidepressant and glucocorticoids. Ann N Y Acad Sci 1179: 144-152.
39. Pariante CM, Kim RB, Makoff A, Kerwin RW (2003). Antidepressant fluoxetine enhances glucocorticoid receptor function in vitro by modulating membrane steroid transporters. Br J Pharmacol 139: 1111-1118. (Pubitemid 36920673)
40. Pariante CM, Makoff A, Lovestone S, Feroli S, Heyden A, Miller AH et al (2001a). Antidepressants enhance glucocorticoid receptor function in vitro by modulating the membrane steroid transporters. Br J Pharmacol 134: 1335-1343. (Pubitemid 33097265)
41. Pariante CM, Miller AH (2001b). Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment. Biol Psychiatry 49: 391-404. (Pubitemid 32234301)
42. Pariante CM, Pearce BD, Pisell TL, Owens MJ, Miller AH (1997). Steroid-independent translocation of the glucocorticoid receptor by the antidepressant desipramine. Mol Pharmacol 52: 571-581. (Pubitemid 27443978)
43. Pepin MC, Govindan MV, Barden N (1992). Increased glucocorticoid receptor gene promoter activity after antidepressant treatment. Mol Pharmacol 41: 1016-1022. (Pubitemid 23026099)
44. Peppi M, Kujawa SG, Sewell WF (2011). A corticosteroid-responsive transcription factor, promyelocytic leukemia zinc finger protein, mediates protection of the cochlea from acoustic trauma. J Neurosci 31: 735-741.
45. R Development Core Team (2007). A Language and Environment for Statistical Computing. R Foundation for Statistical Computing: Vienna.
46. Rollins B, Martin MV, Morgan L, Vawter MP (2010). Analysis of whole genome biomarker expression in blood and brain. Am J Med Genet B Neuropsychiatr Genet 153B: 919-936.
47. Scherzer CR, Eklund AC, Morse LJ, Liao Z, Locascio JJ, Fefer D et al (2007). Molecular markers of early Parkinson's disease based on gene expression in blood. Proc Natl Acad Sci USA 104: 955-960. (Pubitemid 46154718)
48. Schuld A, Birkmann S, Beitinger P, Haack M, Kraus T, Dalal MA et al (2006). Low doses of dexamethasone affect immune parameters in the absence of immunological stimulation. Exp Clin Endocrinol Diabetes 114: 322-328. (Pubitemid 44166180)
49. Segman RH, Goltser-Dubner T, Weiner I, Canetti L, Galili-Weisstub E, Milwidsky A et al (2010). Blood mononuclear cell gene expression signature of postpartum depression. Mol Psychiatry 15: 93-100, 102.
50. Segman RH, Shefi N, Goltser-Dubner T, Friedman N, Kaminski N, Shalev AY (2005). Peripheral blood mononuclear cell gene expression profiles identify emergent post-traumatic stress disorder among trauma survivors. Mol Psychiatry 10: 425, 500-513. (Pubitemid 40646438)
51. Spijker S, Zanten JS, De Jong S, Penninx BW, van Dyck R, Zitman FG et al (2010). Stimulated gene expression profiles as a blood marker of major depressive disorder. Biol Psychiatry 68: 179-186.
52. Sullivan PF, Fan C, Perou CM (2006). Evaluating the comparability of gene expression in blood and brain. Am J Med Genet B Neuropsychiatr Genet 141: 261-268.
53. Tomita H, Vawter MP, Walsh DM, Evans SJ, Choudary PV, Li J et al (2004). Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain. Biol Psychiatry 55: 346-352. (Pubitemid 38199983)
54. Ustun TB, Ayuso-Mateos JL, Chatterji S, Mathers C, Murray CJ (2004). Global burden of depressive disorders in the year 2000. Br J Psychiatry 184: 386-392. (Pubitemid 38624764)
55. Vedder H, Bening-Abu-Shach U, Lanquillon S, Krieg JC (1999). Regulation of glucocorticoid receptor-mRNA in human blood cells by amitriptyline and dexamethasone. J Psychiatr Res 33: 303-308. (Pubitemid 29267633)
56. Vermeer H, Hendriks-Stegeman BI, van der Burg B, van Buul-Offers SC, Jansen M (2003). Glucocorticoid-induced increase in lymphocytic FKBP51 messenger ribonucleic acid expression: a potential marker for glucocorticoid sensitivity, potency, and bioavailability. J Clin Endocrinol Metab 88: 277-284. (Pubitemid 36115178)
57. Wittchen HU, Höfler M, Gander F, Pfister H, Storz S, stün TB et al (1999). Screening for mental disorders: performance of the composite international diagnosticFscreener (CID-S). Int J Methods Psychiatr Res 8: 59-70.
58. Wodarz N, Rupprecht R, Kornhuber J, Schmitz B, Wild K, Riederer P (1992). Cell-mediated immunity and its glucocorticoidsensitivity after clinical recovery from severe major depressive disorder. J Affect Disord 25: 31-38.
59. Yehuda R, Cai G, Golier JA, Sarapas C, Galea S, Ising M et al (2009). Gene expression patterns associated with posttraumatic stress disorder following exposure to the World Trade Center attacks. Biol Psychiatry. 66: 708-711.
60. Young E, Korszun A (2010). Sex, trauma, stress hormones and depression. Mol Psychiatry 15: 23-28.