Increasing ryanodine receptor open probability alone does not produce arrhythmogenic calcium waves: Threshold sarcoplasmic reticulum calcium content is required

Circulation Research

Volumn 100, Issue 1, 2007, Pages 105-111

  Venetucci, Luigi A ^a   Trafford, Andrew W ^a   Eisner, David A ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Arrhythmias; Ca2+ wave; Ryanodine receptor

Indexed keywords

CAFFEINE; ISOPRENALINE; RYANODINE RECEPTOR;

AFTERHYPERPOLARIZATION; AMPLITUDE MODULATION; ANIMAL CELL; ARRHYTHMOGENESIS; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; CONVALESCENCE; HEART MUSCLE CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR INTRINSIC ACTIVITY; SARCOPLASMIC RETICULUM; STEADY STATE; SYSTOLE;

ADRENERGIC BETA-AGONISTS; ANIMALS; ARRHYTHMIA; CAFFEINE; CALCIUM; DIASTOLE; DIFFERENTIAL THRESHOLD; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART VENTRICLES; ISOPROTERENOL; MALE; MYOCARDIUM; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SYSTOLE;

EID: 33846117456     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000252828.17939.00     Document Type: Article

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