Systemic versus localized coagulation activation contributing to organ failure in critically ill patients

Seminars in Immunopathology

Volumn 34, Issue 1, 2012, Pages 167-179

  Levi, Marcel ^a   Van Der Poll, Tom ^a   Schultz, Marcus ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Coagulation; Inflammation

Indexed keywords

ACTIVATED PROTEIN C; ANTICOAGULANT AGENT; ANTITHROMBIN; BLOOD CLOTTING FACTOR 7A; FIBRIN; INTERLEUKIN 1; INTERLEUKIN 6; PROTEINASE ACTIVATED RECEPTOR 2; RECOMBINANT TISSUE FACTOR PATHWAY INHIBITOR; THROMBIN; THROMBOPLASTIN; AUTACOID; IL6 PROTEIN, HUMAN;

BINDING SITE; BLOOD CLOTTING; CRITICALLY ILL PATIENT; CYTOKINE RELEASE; DISEASE ASSOCIATION; DISEASE SEVERITY; DISSEMINATED INTRAVASCULAR CLOTTING; DOWN REGULATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENDOTHELIUM CELL; FIBRIN DEPOSITION; GASTROINTESTINAL TRACT FUNCTION; HUMAN; IMMUNOMODULATION; IN VIVO STUDY; INFECTION; INFLAMMATION; INTRACELLULAR SIGNALING; KIDNEY FUNCTION; LIVER FUNCTION; LUNG FUNCTION; MULTIPLE ORGAN FAILURE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; SEPSIS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THROMBOCYTE ACTIVATION; BLOOD; CRITICAL ILLNESS; FIBRINOLYSIS; IMMUNOLOGY; METABOLISM; MONONUCLEAR CELL; PATHOLOGY;

CRITICAL ILLNESS; ENDOTHELIAL CELLS; FIBRINOLYSIS; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; MULTIPLE ORGAN FAILURE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THROMBIN;

EID: 84859733874     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-011-0283-7     Document Type: Review

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